-
1
-
-
84885366143
-
CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
-
Abdelmegeed MA, Banerjee A, Jang S, Yoo SH, Yun JW, Gonzalez FJ, Keshavarzian A, Song BJ (2013) CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. Free Radic Biol Med 65:1238-1245.
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 1238-1245
-
-
Abdelmegeed, M.A.1
Banerjee, A.2
Jang, S.3
Yoo, S.H.4
Yun, J.W.5
Gonzalez, F.J.6
Keshavarzian, A.7
Song, B.J.8
-
2
-
-
0028108372
-
Inactivation of Kupffer cells prevents early alcohol-induced liver injury
-
Adachi Y, Bradford BU, Gao W, Bojes HK, Thurman RG (1994) Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20:453-460.
-
(1994)
Hepatology
, vol.20
, pp. 453-460
-
-
Adachi, Y.1
Bradford, B.U.2
Gao, W.3
Bojes, H.K.4
Thurman, R.G.5
-
3
-
-
0028796860
-
Antibiotics prevent liver injury in rats following long-term exposure to ethanol
-
Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG (1995) Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 108:218-224.
-
(1995)
Gastroenterology
, vol.108
, pp. 218-224
-
-
Adachi, Y.1
Moore, L.E.2
Bradford, B.U.3
Gao, W.4
Thurman, R.G.5
-
4
-
-
0030848926
-
Influence of alcohol on gastrointestinal motility: lactulose breath hydrogen testing in orocecal transit time in chronic alcoholics, social drinkers and teetotaler subjects
-
Addolorato G, Montalto M, Capristo E, Certo M, Fedeli G, Gentiloni N, Stefanini GF, Gasbarrini G (1997) Influence of alcohol on gastrointestinal motility: lactulose breath hydrogen testing in orocecal transit time in chronic alcoholics, social drinkers and teetotaler subjects. Hepatogastroenterology 44:1076-1081.
-
(1997)
Hepatogastroenterology
, vol.44
, pp. 1076-1081
-
-
Addolorato, G.1
Montalto, M.2
Capristo, E.3
Certo, M.4
Fedeli, G.5
Gentiloni, N.6
Stefanini, G.F.7
Gasbarrini, G.8
-
5
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
6
-
-
77957327198
-
Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis
-
Arvaniti V, D'Amico G, Fede G, Manousou P, Tsochatzis E, Pleguezuelo M, Burroughs AK (2010) Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis. Gastroenterology 139:1246-1256, 1256.e1-5.
-
(2010)
Gastroenterology
, vol.139
, pp. 1246-1256
-
-
Arvaniti, V.1
D'Amico, G.2
Fede, G.3
Manousou, P.4
Tsochatzis, E.5
Pleguezuelo, M.6
Burroughs, A.K.7
-
7
-
-
84922392216
-
Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function
-
Bajaj JS, Cox IJ, Betrapally NS, Heuman DM, Schubert ML, Ratneswaran M, Hylemon PB, White MB, Daita K, Noble NA, Sikaroodi M, Williams R, Crossey MM, Taylor-Robinson SD, Gillevet PM (2014a) Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function. Am J Physiol Gastrointest Liver Physiol 307:G951-G957.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.307
, pp. G951-G957
-
-
Bajaj, J.S.1
Cox, I.J.2
Betrapally, N.S.3
Heuman, D.M.4
Schubert, M.L.5
Ratneswaran, M.6
Hylemon, P.B.7
White, M.B.8
Daita, K.9
Noble, N.A.10
Sikaroodi, M.11
Williams, R.12
Crossey, M.M.13
Taylor-Robinson, S.D.14
Gillevet, P.M.15
-
8
-
-
84899046306
-
Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis
-
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, Puri P, Sterling RK, Luketic V, Stravitz RT, Siddiqui MS, Fuchs M, Thacker LR, Wade JB, Daita K, Sistrun S, White MB, Noble NA, Thorpe C, Kakiyama G, Pandak WM, Sikaroodi M, Gillevet PM (2014b) Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Aliment Pharmacol Ther 39:1113-1125.
-
(2014)
Aliment Pharmacol Ther
, vol.39
, pp. 1113-1125
-
-
Bajaj, J.S.1
Heuman, D.M.2
Hylemon, P.B.3
Sanyal, A.J.4
Puri, P.5
Sterling, R.K.6
Luketic, V.7
Stravitz, R.T.8
Siddiqui, M.S.9
Fuchs, M.10
Thacker, L.R.11
Wade, J.B.12
Daita, K.13
Sistrun, S.14
White, M.B.15
Noble, N.A.16
Thorpe, C.17
Kakiyama, G.18
Pandak, W.M.19
Sikaroodi, M.20
Gillevet, P.M.21
more..
-
9
-
-
84898830272
-
Altered profile of human gut microbiome is associated with cirrhosis and its complications
-
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, White MB, Monteith P, Noble NA, Unser AB, Daita K, Fisher AR, Sikaroodi M, Gillevet PM (2014c) Altered profile of human gut microbiome is associated with cirrhosis and its complications. J Hepatol 60:940-947.
-
(2014)
J Hepatol
, vol.60
, pp. 940-947
-
-
Bajaj, J.S.1
Heuman, D.M.2
Hylemon, P.B.3
Sanyal, A.J.4
White, M.B.5
Monteith, P.6
Noble, N.A.7
Unser, A.B.8
Daita, K.9
Fisher, A.R.10
Sikaroodi, M.11
Gillevet, P.M.12
-
10
-
-
84875670330
-
Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy
-
Bajaj JS, Heuman DM, Sanyal AJ, Hylemon PB, Sterling RK, Stravitz RT, Fuchs M, Ridlon JM, Daita K, Monteith P, Noble NA, White MB, Fisher A, Sikaroodi M, Rangwala H, Gillevet PM (2013) Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. PLoS One 8:e60042.
-
(2013)
PLoS One
, vol.8
, pp. e60042
-
-
Bajaj, J.S.1
Heuman, D.M.2
Sanyal, A.J.3
Hylemon, P.B.4
Sterling, R.K.5
Stravitz, R.T.6
Fuchs, M.7
Ridlon, J.M.8
Daita, K.9
Monteith, P.10
Noble, N.A.11
White, M.B.12
Fisher, A.13
Sikaroodi, M.14
Rangwala, H.15
Gillevet, P.M.16
-
11
-
-
84866396844
-
Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation
-
Bajaj JS, Hylemon PB, Ridlon JM, Heuman DM, Daita K, White MB, Monteith P, Noble NA, Sikaroodi M, Gillevet PM (2012a) Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation. Am J Physiol Gastrointest Liver Physiol 303:G675-G685.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.303
, pp. G675-G685
-
-
Bajaj, J.S.1
Hylemon, P.B.2
Ridlon, J.M.3
Heuman, D.M.4
Daita, K.5
White, M.B.6
Monteith, P.7
Noble, N.A.8
Sikaroodi, M.9
Gillevet, P.M.10
-
12
-
-
83755186465
-
Linkage of gut microbiome with cognition in hepatic encephalopathy
-
Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, Heuman DM, Smith S, Sikaroodi M, Gillevet PM (2012b) Linkage of gut microbiome with cognition in hepatic encephalopathy. Am J Physiol Gastrointest Liver Physiol 302:G168-G175.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
, pp. G168-G175
-
-
Bajaj, J.S.1
Ridlon, J.M.2
Hylemon, P.B.3
Thacker, L.R.4
Heuman, D.M.5
Smith, S.6
Sikaroodi, M.7
Gillevet, P.M.8
-
13
-
-
0032753747
-
Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms
-
Banan A, Choudhary S, Zhang Y, Fields JZ, Keshavarzian A (1999) Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms. J Pharmacol Exp Ther 291:1075-1085.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 1075-1085
-
-
Banan, A.1
Choudhary, S.2
Zhang, Y.3
Fields, J.Z.4
Keshavarzian, A.5
-
14
-
-
0033841219
-
Diagnosis of small intestinal bacterial overgrowth in patients with cirrhosis of the liver: poor performance of the glucose breath hydrogen test
-
Bauer TM, Schwacha H, Steinbruckner B, Brinkmann FE, Ditzen AK, Kist M, Blum HE (2000) Diagnosis of small intestinal bacterial overgrowth in patients with cirrhosis of the liver: poor performance of the glucose breath hydrogen test. J Hepatol 33:382-386.
-
(2000)
J Hepatol
, vol.33
, pp. 382-386
-
-
Bauer, T.M.1
Schwacha, H.2
Steinbruckner, B.3
Brinkmann, F.E.4
Ditzen, A.K.5
Kist, M.6
Blum, H.E.7
-
15
-
-
0018404843
-
Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model
-
Berg RD, Garlington AW (1979) Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model. Infect Immun 23:403-411.
-
(1979)
Infect Immun
, vol.23
, pp. 403-411
-
-
Berg, R.D.1
Garlington, A.W.2
-
16
-
-
18244431246
-
Effect of treatment with paromomycin on endotoxemia in patients with alcoholic liver disease-a double-blind, placebo-controlled trial
-
Bode C, Schafer C, Fukui H, Bode JC (1997) Effect of treatment with paromomycin on endotoxemia in patients with alcoholic liver disease-a double-blind, placebo-controlled trial. Alcohol Clin Exp Res 21:1367-1373.
-
(1997)
Alcohol Clin Exp Res
, vol.21
, pp. 1367-1373
-
-
Bode, C.1
Schafer, C.2
Fukui, H.3
Bode, J.C.4
-
17
-
-
0021235523
-
Jejunal microflora in patients with chronic alcohol abuse
-
Bode JC, Bode C, Heidelbach R, Durr HK, Martini GA (1984) Jejunal microflora in patients with chronic alcohol abuse. Hepatogastroenterology 31:30-34.
-
(1984)
Hepatogastroenterology
, vol.31
, pp. 30-34
-
-
Bode, J.C.1
Bode, C.2
Heidelbach, R.3
Durr, H.K.4
Martini, G.A.5
-
18
-
-
84923849535
-
Implication of gut microbiota in nonalcoholic fatty liver disease
-
Boursier J, Diehl AM (2015) Implication of gut microbiota in nonalcoholic fatty liver disease. PLoS Pathog 11:e1004559.
-
(2015)
PLoS Pathog
, vol.11
, pp. e1004559
-
-
Boursier, J.1
Diehl, A.M.2
-
19
-
-
84872246853
-
Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment
-
Bull-Otterson L, Feng W, Kirpich I, Wang Y, Qin X, Liu Y, Gobejishvili L, Joshi-Barve S, Ayvaz T, Petrosino J, Kong M, Barker D, McClain C, Barve S (2013) Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment. PLoS One 8:e53028.
-
(2013)
PLoS One
, vol.8
, pp. e53028
-
-
Bull-Otterson, L.1
Feng, W.2
Kirpich, I.3
Wang, Y.4
Qin, X.5
Liu, Y.6
Gobejishvili, L.7
Joshi-Barve, S.8
Ayvaz, T.9
Petrosino, J.10
Kong, M.11
Barker, D.12
McClain, C.13
Barve, S.14
-
20
-
-
84908128911
-
Comparing the effects of acute alcohol consumption in germ-free and conventional mice: the role of the gut microbiota
-
Campos Canesso M, Lacerda Queiroz N, Marcantonio C, Lauar J, Almeida D, Gamba C, Cassali G, Pedroso S, Moreira C, Santos Martins F, Nicoli J, Martins Teixeira M, Brunialti Godard A, Thomaz Vieira A (2014) Comparing the effects of acute alcohol consumption in germ-free and conventional mice: the role of the gut microbiota. BMC Microbiol 14:240.
-
(2014)
BMC Microbiol
, vol.14
, pp. 240
-
-
Campos Canesso, M.1
Lacerda Queiroz, N.2
Marcantonio, C.3
Lauar, J.4
Almeida, D.5
Gamba, C.6
Cassali, G.7
Pedroso, S.8
Moreira, C.9
Santos Martins, F.10
Nicoli, J.11
Martins Teixeira, M.12
Brunialti Godard, A.13
Thomaz Vieira, A.14
-
21
-
-
9244231742
-
Small bowel bacterial overgrowth in patients with alcoholic cirrhosis
-
Casafont Morencos F, De Las Heras Castano G, Martin Ramos L, Lopez Arias MJ, Ledesma F, Pons Romero F (1996) Small bowel bacterial overgrowth in patients with alcoholic cirrhosis. Dig Dis Sci 41:552-556.
-
(1996)
Dig Dis Sci
, vol.41
, pp. 552-556
-
-
Casafont Morencos, F.1
De Las Heras Castano, G.2
Martin Ramos, L.3
Lopez Arias, M.J.4
Ledesma, F.5
Pons Romero, F.6
-
22
-
-
0027322336
-
Alcohol and gastric acid secretion in humans
-
Chari S, Teyssen S, Singer MV (1993) Alcohol and gastric acid secretion in humans. Gut 34:843-847.
-
(1993)
Gut
, vol.34
, pp. 843-847
-
-
Chari, S.1
Teyssen, S.2
Singer, M.V.3
-
23
-
-
84923468701
-
Dysbiosis-induced intestinal inflammation activates TNFRI and mediates alcoholic liver disease in mice
-
Chen P, Starkel P, Turner JR, Ho SB, Schnabl B (2015a) Dysbiosis-induced intestinal inflammation activates TNFRI and mediates alcoholic liver disease in mice. Hepatology 61:883-894.
-
(2015)
Hepatology
, vol.61
, pp. 883-894
-
-
Chen, P.1
Starkel, P.2
Turner, J.R.3
Ho, S.B.4
Schnabl, B.5
-
24
-
-
84922630906
-
Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice
-
e16
-
Chen P, Torralba M, Tan J, Embree M, Zengler K, Starkel P, Van Pijkeren JP, Depew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B (2015b) Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. Gastroenterology 148:203-214 e16.
-
(2015)
Gastroenterology
, vol.148
, pp. 203-214
-
-
Chen, P.1
Torralba, M.2
Tan, J.3
Embree, M.4
Zengler, K.5
Starkel, P.6
Van Pijkeren, J.P.7
Depew, J.8
Loomba, R.9
Ho, S.B.10
Bajaj, J.S.11
Mutlu, E.A.12
Keshavarzian, A.13
Tsukamoto, H.14
Nelson, K.E.15
Fouts, D.E.16
Schnabl, B.17
-
25
-
-
79960714764
-
Characterization of fecal microbial communities in patients with liver cirrhosis
-
Chen Y, Yang F, Lu H, Wang B, Lei D, Wang Y, Zhu B, Li L (2011) Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology 54:562-572.
-
(2011)
Hepatology
, vol.54
, pp. 562-572
-
-
Chen, Y.1
Yang, F.2
Lu, H.3
Wang, B.4
Lei, D.5
Wang, Y.6
Zhu, B.7
Li, L.8
-
26
-
-
84865477413
-
Antibiotics in early life alter the murine colonic microbiome and adiposity
-
Cho I, Yamanishi S, Cox L, Methe BA, Zavadil J, Li K, Gao Z, Mahana D, Raju K, Teitler I, Li H, Alekseyenko AV, Blaser MJ (2012) Antibiotics in early life alter the murine colonic microbiome and adiposity. Nature 488:621-626.
-
(2012)
Nature
, vol.488
, pp. 621-626
-
-
Cho, I.1
Yamanishi, S.2
Cox, L.3
Methe, B.A.4
Zavadil, J.5
Li, K.6
Gao, Z.7
Mahana, D.8
Raju, K.9
Teitler, I.10
Li, H.11
Alekseyenko, A.V.12
Blaser, M.J.13
-
27
-
-
84916624047
-
Postbiotic activities of lactobacilli-derived factors
-
Cicenia A, Scirocco A, Carabotti M, Pallotta L, Marignani M, Severi C (2014) Postbiotic activities of lactobacilli-derived factors. J Clin Gastroenterol 48(Suppl 1):S18-S22.
-
(2014)
J Clin Gastroenterol
, vol.48
, pp. S18-S22
-
-
Cicenia, A.1
Scirocco, A.2
Carabotti, M.3
Pallotta, L.4
Marignani, M.5
Severi, C.6
-
28
-
-
84887227527
-
Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury
-
Cresci G, Nagy LE, Ganapathy V (2013) Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury. J Parenter Enteral Nutr 37:763-774.
-
(2013)
J Parenter Enteral Nutr
, vol.37
, pp. 763-774
-
-
Cresci, G.1
Nagy, L.E.2
Ganapathy, V.3
-
29
-
-
84901932901
-
Tributyrin supplementation protects mice from acute ethanol-induced gut injury
-
Cresci GA, Bush K, Nagy LE (2014) Tributyrin supplementation protects mice from acute ethanol-induced gut injury. Alcohol Clin Exp Res 38:1489-1501.
-
(2014)
Alcohol Clin Exp Res
, vol.38
, pp. 1489-1501
-
-
Cresci, G.A.1
Bush, K.2
Nagy, L.E.3
-
30
-
-
84913553798
-
Probiotic VSL#3 reduces liver disease severity and hospitalization in patients with cirrhosis: a randomized, controlled trial
-
e3
-
Dhiman RK, Rana B, Agrawal S, Garg A, Chopra M, Thumburu KK, Khattri A, Malhotra S, Duseja A, Chawla YK (2014) Probiotic VSL#3 reduces liver disease severity and hospitalization in patients with cirrhosis: a randomized, controlled trial. Gastroenterology 147:1327-1337.e3.
-
(2014)
Gastroenterology
, vol.147
, pp. 1327-1337
-
-
Dhiman, R.K.1
Rana, B.2
Agrawal, S.3
Garg, A.4
Chopra, M.5
Thumburu, K.K.6
Khattri, A.7
Malhotra, S.8
Duseja, A.9
Chawla, Y.K.10
-
31
-
-
0015435219
-
Gastric secretion and gastric mucosal morphology in chronic alcoholics
-
Dinoso VP Jr, Chey WY, Braverman SP, Rosen AP, Ottenberg D, Lorber SH (1972) Gastric secretion and gastric mucosal morphology in chronic alcoholics. Arch Intern Med 130:715-719.
-
(1972)
Arch Intern Med
, vol.130
, pp. 715-719
-
-
Dinoso Jr, V.P.1
Chey, W.Y.2
Braverman, S.P.3
Rosen, A.P.4
Ottenberg, D.5
Lorber, S.H.6
-
32
-
-
12844250743
-
Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar Typhimurium systemic infection
-
Fadl AA, Sha J, Klimpel GR, Olano JP, Niesel DW, Chopra AK (2005) Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar Typhimurium systemic infection. Infect Immun 73:1081-1096.
-
(2005)
Infect Immun
, vol.73
, pp. 1081-1096
-
-
Fadl, A.A.1
Sha, J.2
Klimpel, G.R.3
Olano, J.P.4
Niesel, D.W.5
Chopra, A.K.6
-
33
-
-
33645449666
-
Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents
-
Ferrier L, Berard F, Debrauwer L, Chabo C, Langella P, Bueno L, Fioramonti J (2006) Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents. Am J Pathol 168:1148-1154.
-
(2006)
Am J Pathol
, vol.168
, pp. 1148-1154
-
-
Ferrier, L.1
Berard, F.2
Debrauwer, L.3
Chabo, C.4
Langella, P.5
Bueno, L.6
Fioramonti, J.7
-
34
-
-
0035049639
-
Pro- and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol
-
Fleming S, Toratani S, Shea-Donohue T, Kashiwabara Y, Vogel SN, Metcalf ES (2001) Pro- and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol. Alcohol Clin Exp Res 25:579-589.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 579-589
-
-
Fleming, S.1
Toratani, S.2
Shea-Donohue, T.3
Kashiwabara, Y.4
Vogel, S.N.5
Metcalf, E.S.6
-
35
-
-
84896731920
-
The impact of alcohol consumption and cholecystectomy on small intestinal bacterial overgrowth
-
Gabbard SL, Lacy BE, Levine GM, Crowell MD (2014) The impact of alcohol consumption and cholecystectomy on small intestinal bacterial overgrowth. Dig Dis Sci 59:638-644.
-
(2014)
Dig Dis Sci
, vol.59
, pp. 638-644
-
-
Gabbard, S.L.1
Lacy, B.E.2
Levine, G.M.3
Crowell, M.D.4
-
36
-
-
80054872790
-
Alcoholic liver disease: pathogenesis and new therapeutic targets
-
Gao B, Bataller R (2011) Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 141:1572-1585.
-
(2011)
Gastroenterology
, vol.141
, pp. 1572-1585
-
-
Gao, B.1
Bataller, R.2
-
37
-
-
33744804299
-
Metagenomic analysis of the human distal gut microbiome
-
Gill SR, Pop M, Deboy RT, Eckburg PB, Turnbaugh PJ, Samuel BS, Gordon JI, Relman DA, Fraser-Liggett CM, Nelson KE (2006) Metagenomic analysis of the human distal gut microbiome. Science 312:1355-1359.
-
(2006)
Science
, vol.312
, pp. 1355-1359
-
-
Gill, S.R.1
Pop, M.2
Deboy, R.T.3
Eckburg, P.B.4
Turnbaugh, P.J.5
Samuel, B.S.6
Gordon, J.I.7
Relman, D.A.8
Fraser-Liggett, C.M.9
Nelson, K.E.10
-
38
-
-
84910096224
-
Human genetics shape the gut microbiome
-
Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark AG, Ley RE (2014) Human genetics shape the gut microbiome. Cell 159:789-799.
-
(2014)
Cell
, vol.159
, pp. 789-799
-
-
Goodrich, J.K.1
Waters, J.L.2
Poole, A.C.3
Sutter, J.L.4
Koren, O.5
Blekhman, R.6
Beaumont, M.7
Van Treuren, W.8
Knight, R.9
Bell, J.T.10
Spector, T.D.11
Clark, A.G.12
Ley, R.E.13
-
39
-
-
0030874289
-
Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites
-
Guarner C, Runyon BA, Young S, Heck M, Sheikh MY (1997) Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites. J Hepatol 26:1372-1378.
-
(1997)
J Hepatol
, vol.26
, pp. 1372-1378
-
-
Guarner, C.1
Runyon, B.A.2
Young, S.3
Heck, M.4
Sheikh, M.Y.5
-
40
-
-
77957345947
-
Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathy
-
Gupta A, Dhiman RK, Kumari S, Rana S, Agarwal R, Duseja A, Chawla Y (2010) Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathy. J Hepatol 53:849-855.
-
(2010)
J Hepatol
, vol.53
, pp. 849-855
-
-
Gupta, A.1
Dhiman, R.K.2
Kumari, S.3
Rana, S.4
Agarwal, R.5
Duseja, A.6
Chawla, Y.7
-
41
-
-
84879600829
-
Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice
-
Hartmann P, Chen P, Wang HJ, Wang L, McCole DF, Brandl K, Starkel P, Belzer C, Hellerbrand C, Tsukamoto H, Ho SB, Schnabl B (2013) Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice. Hepatology 58:108-119.
-
(2013)
Hepatology
, vol.58
, pp. 108-119
-
-
Hartmann, P.1
Chen, P.2
Wang, H.J.3
Wang, L.4
McCole, D.F.5
Brandl, K.6
Starkel, P.7
Belzer, C.8
Hellerbrand, C.9
Tsukamoto, H.10
Ho, S.B.11
Schnabl, B.12
-
42
-
-
84870880811
-
The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease
-
Hartmann P, Chen WC, Schnabl B (2012) The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease. Front Physiol 3:402.
-
(2012)
Front Physiol
, vol.3
, pp. 402
-
-
Hartmann, P.1
Chen, W.C.2
Schnabl, B.3
-
43
-
-
54449092214
-
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88
-
Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G (2008) The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology 48:1224-1231.
-
(2008)
Hepatology
, vol.48
, pp. 1224-1231
-
-
Hritz, I.1
Mandrekar, P.2
Velayudham, A.3
Catalano, D.4
Dolganiuc, A.5
Kodys, K.6
Kurt-Jones, E.7
Szabo, G.8
-
44
-
-
33644867569
-
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
-
Inagaki T, Moschetta A, Lee YK, Peng L, Zhao G, Downes M, Yu RT, Shelton JM, Richardson JA, Repa JJ, Mangelsdorf DJ, Kliewer SA (2006) Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci USA 103:3920-3925.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3920-3925
-
-
Inagaki, T.1
Moschetta, A.2
Lee, Y.K.3
Peng, L.4
Zhao, G.5
Downes, M.6
Yu, R.T.7
Shelton, J.M.8
Richardson, J.A.9
Repa, J.J.10
Mangelsdorf, D.J.11
Kliewer, S.A.12
-
45
-
-
79959811718
-
Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice
-
Inokuchi S, Tsukamoto H, Park E, Liu ZX, Brenner DA, Seki E (2011) Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res 35:1509-1518.
-
(2011)
Alcohol Clin Exp Res
, vol.35
, pp. 1509-1518
-
-
Inokuchi, S.1
Tsukamoto, H.2
Park, E.3
Liu, Z.X.4
Brenner, D.A.5
Seki, E.6
-
46
-
-
84901697873
-
Colonic inflammation and secondary bile acids in alcoholic cirrhosis
-
Kakiyama G, Hylemon PB, Zhou H, Pandak WM, Heuman DM, Kang DJ, Takei H, Nittono H, Ridlon JM, Fuchs M, Gurley EC, Wang Y, Liu R, Sanyal AJ, Gillevet PM, Bajaj JS (2014) Colonic inflammation and secondary bile acids in alcoholic cirrhosis. Am J Physiol Gastrointest Liver Physiol 306:G929-G937.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.306
, pp. G929-G937
-
-
Kakiyama, G.1
Hylemon, P.B.2
Zhou, H.3
Pandak, W.M.4
Heuman, D.M.5
Kang, D.J.6
Takei, H.7
Nittono, H.8
Ridlon, J.M.9
Fuchs, M.10
Gurley, E.C.11
Wang, Y.12
Liu, R.13
Sanyal, A.J.14
Gillevet, P.M.15
Bajaj, J.S.16
-
47
-
-
84876294967
-
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
-
Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, Sikaroodi M, Bajaj JS (2013) Modulation of the fecal bile acid profile by gut microbiota in cirrhosis. J Hepatol 58:949-955.
-
(2013)
J Hepatol
, vol.58
, pp. 949-955
-
-
Kakiyama, G.1
Pandak, W.M.2
Gillevet, P.M.3
Hylemon, P.B.4
Heuman, D.M.5
Daita, K.6
Takei, H.7
Muto, A.8
Nittono, H.9
Ridlon, J.M.10
White, M.B.11
Noble, N.A.12
Monteith, P.13
Fuchs, M.14
Thacker, L.R.15
Sikaroodi, M.16
Bajaj, J.S.17
-
48
-
-
52149084370
-
S-adenosyl-l-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model
-
Karaa A, Thompson KJ, McKillop IH, Clemens MG, Schrum LW (2008) S-adenosyl-l-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model. Shock 30:197-205.
-
(2008)
Shock
, vol.30
, pp. 197-205
-
-
Karaa, A.1
Thompson, K.J.2
McKillop, I.H.3
Clemens, M.G.4
Schrum, L.W.5
-
49
-
-
0023805369
-
Breath hydrogen testing in bacterial overgrowth of the small intestine
-
Kerlin P, Wong L (1988) Breath hydrogen testing in bacterial overgrowth of the small intestine. Gastroenterology 95:982-988.
-
(1988)
Gastroenterology
, vol.95
, pp. 982-988
-
-
Kerlin, P.1
Wong, L.2
-
50
-
-
84860433691
-
The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease
-
Kirpich IA, Feng W, Wang Y, Liu Y, Barker DF, Barve SS, McClain CJ (2012) The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease. Alcohol Clin Exp Res 36:835-846.
-
(2012)
Alcohol Clin Exp Res
, vol.36
, pp. 835-846
-
-
Kirpich, I.A.1
Feng, W.2
Wang, Y.3
Liu, Y.4
Barker, D.F.5
Barve, S.S.6
McClain, C.J.7
-
51
-
-
56349169101
-
Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study
-
Kirpich IA, Solovieva NV, Leikhter SN, Shidakova NA, Lebedeva OV, Sidorov PI, Bazhukova TA, Soloviev AG, Barve SS, McClain CJ, Cave M (2008) Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study. Alcohol 42:675-682.
-
(2008)
Alcohol
, vol.42
, pp. 675-682
-
-
Kirpich, I.A.1
Solovieva, N.V.2
Leikhter, S.N.3
Shidakova, N.A.4
Lebedeva, O.V.5
Sidorov, P.I.6
Bazhukova, T.A.7
Soloviev, A.G.8
Barve, S.S.9
McClain, C.J.10
Cave, M.11
-
52
-
-
67349139869
-
Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model
-
Kudo H, Takahara T, Yata Y, Kawai K, Zhang W, Sugiyama T (2009) Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model. J Hepatol 51:168-175.
-
(2009)
J Hepatol
, vol.51
, pp. 168-175
-
-
Kudo, H.1
Takahara, T.2
Yata, Y.3
Kawai, K.4
Zhang, W.5
Sugiyama, T.6
-
53
-
-
36249031636
-
The effect of probiotics on gut flora, level of endotoxin and Child-Pugh score in cirrhotic patients: results of a double-blind randomized study
-
Lata J, Novotny I, Pribramska V, Jurankova J, Fric P, Kroupa R, Stiburek O (2007) The effect of probiotics on gut flora, level of endotoxin and Child-Pugh score in cirrhotic patients: results of a double-blind randomized study. Eur J Gastro Hepatol 19:1111-1113.
-
(2007)
Eur J Gastro Hepatol
, vol.19
, pp. 1111-1113
-
-
Lata, J.1
Novotny, I.2
Pribramska, V.3
Jurankova, J.4
Fric, P.5
Kroupa, R.6
Stiburek, O.7
-
54
-
-
84908043065
-
Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
-
Leclercq S, Matamoros S, Cani PD, Neyrinck AM, Jamar F, Starkel P, Windey K, Tremaroli V, Backhed F, Verbeke K, De Timary P, Delzenne NM (2014) Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity. Proc Natl Acad Sci USA 111:E4485-E4493.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E4485-E4493
-
-
Leclercq, S.1
Matamoros, S.2
Cani, P.D.3
Neyrinck, A.M.4
Jamar, F.5
Starkel, P.6
Windey, K.7
Tremaroli, V.8
Backhed, F.9
Verbeke, K.10
De Timary, P.11
Delzenne, N.M.12
-
55
-
-
84864390922
-
The epidemiology, pathogenesis and histopathology of fatty liver disease
-
Levene AP, Goldin RD (2012) The epidemiology, pathogenesis and histopathology of fatty liver disease. Histopathology 61:141-152.
-
(2012)
Histopathology
, vol.61
, pp. 141-152
-
-
Levene, A.P.1
Goldin, R.D.2
-
56
-
-
33845901507
-
Microbial ecology: human gut microbes associated with obesity
-
Ley RE, Turnbaugh PJ, Klein S, Gordon JI (2006) Microbial ecology: human gut microbes associated with obesity. Nature 444:1022-1023.
-
(2006)
Nature
, vol.444
, pp. 1022-1023
-
-
Ley, R.E.1
Turnbaugh, P.J.2
Klein, S.3
Gordon, J.I.4
-
57
-
-
0025136962
-
Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth
-
Lichtman SN, Sartor RB, Keku J, Schwab JH (1990) Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth. Gastroenterology 98:414-423.
-
(1990)
Gastroenterology
, vol.98
, pp. 414-423
-
-
Lichtman, S.N.1
Sartor, R.B.2
Keku, J.3
Schwab, J.H.4
-
58
-
-
0000156898
-
Effects of prolonged ethanol intake: production of fatty liver despite adequate diets
-
Lieber CS, Jones DP, Decarli LM (1965) Effects of prolonged ethanol intake: production of fatty liver despite adequate diets. J Clin Invest 44:1009-1021.
-
(1965)
J Clin Invest
, vol.44
, pp. 1009-1021
-
-
Lieber, C.S.1
Jones, D.P.2
Decarli, L.M.3
-
59
-
-
0028934072
-
Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation
-
Lin RS, Lee FY, Lee SD, Tsai YT, Lin HC, Lu RH, Hsu WC, Huang CC, Wang SS, Lo KJ (1995) Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation. J Hepatol 22:165-172.
-
(1995)
J Hepatol
, vol.22
, pp. 165-172
-
-
Lin, R.S.1
Lee, F.Y.2
Lee, S.D.3
Tsai, Y.T.4
Lin, H.C.5
Lu, R.H.6
Hsu, W.C.7
Huang, C.C.8
Wang, S.S.9
Lo, K.J.10
-
60
-
-
84910646076
-
Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver
-
Liu J (2014) Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver. World J Gastroenterol 20:14672-14685.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 14672-14685
-
-
Liu, J.1
-
61
-
-
2342580955
-
Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis
-
Liu Q, Duan ZP, Ha DK, Bengmark S, Kurtovic J, Riordan SM (2004) Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis. Hepatology 39:1441-1449.
-
(2004)
Hepatology
, vol.39
, pp. 1441-1449
-
-
Liu, Q.1
Duan, Z.P.2
Ha, D.K.3
Bengmark, S.4
Kurtovic, J.5
Riordan, S.M.6
-
62
-
-
20844440555
-
Beneficial effects of a probiotic VSL#3 on parameters of liver dysfunction in chronic liver diseases
-
Loguercio C, Federico A, Tuccillo C, Terracciano F, D'Auria MV, De Simone C, Del Vecchio Blanco C (2005) Beneficial effects of a probiotic VSL#3 on parameters of liver dysfunction in chronic liver diseases. J Clin Gastroenterol 39:540-543.
-
(2005)
J Clin Gastroenterol
, vol.39
, pp. 540-543
-
-
Loguercio, C.1
Federico, A.2
Tuccillo, C.3
Terracciano, F.4
D'Auria, M.V.5
De Simone, C.6
Del Vecchio Blanco, C.7
-
63
-
-
70350752461
-
Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: the Rancho Bernardo Study
-
Loomba R, Bettencourt R, Barrett-Connor E (2009) Synergistic association between alcohol intake and body mass index with serum alanine and aspartate aminotransferase levels in older adults: the Rancho Bernardo Study. Aliment Pharmacol Ther 30:1137-1149.
-
(2009)
Aliment Pharmacol Ther
, vol.30
, pp. 1137-1149
-
-
Loomba, R.1
Bettencourt, R.2
Barrett-Connor, E.3
-
64
-
-
0037372737
-
Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
-
Lorenzo-Zuniga V, Bartoli R, Planas R, Hofmann AF, Vinado B, Hagey LR, Hernandez JM, Mane J, Alvarez MA, Ausina V, Gassull MA (2003) Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats. Hepatology 37:551-557.
-
(2003)
Hepatology
, vol.37
, pp. 551-557
-
-
Lorenzo-Zuniga, V.1
Bartoli, R.2
Planas, R.3
Hofmann, A.F.4
Vinado, B.5
Hagey, L.R.6
Hernandez, J.M.7
Mane, J.8
Alvarez, M.A.9
Ausina, V.10
Gassull, M.A.11
-
65
-
-
84901200252
-
Probiotics prevent hepatic encephalopathy in patients with cirrhosis: a randomized controlled trial
-
e1
-
Lunia MK, Sharma BC, Sharma P, Sachdeva S, Srivastava S (2014) Probiotics prevent hepatic encephalopathy in patients with cirrhosis: a randomized controlled trial. Clin Gastroenterol Hepatol 12:1003-1008.e1.
-
(2014)
Clin Gastroenterol Hepatol
, vol.12
, pp. 1003-1008
-
-
Lunia, M.K.1
Sharma, B.C.2
Sharma, P.3
Sachdeva, S.4
Srivastava, S.5
-
66
-
-
0035046242
-
Long-Term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function
-
Madrid AM, Hurtado C, Venegas M, Cumsille F, Defilippi C (2001) Long-Term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function. Am J Gastroenterol 96:1251-1255.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 1251-1255
-
-
Madrid, A.M.1
Hurtado, C.2
Venegas, M.3
Cumsille, F.4
Defilippi, C.5
-
67
-
-
84927644391
-
Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice
-
Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B (2015) Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB J 29:1043-1055.
-
(2015)
FASEB J
, vol.29
, pp. 1043-1055
-
-
Mazagova, M.1
Wang, L.2
Anfora, A.T.3
Wissmueller, M.4
Lesley, S.A.5
Miyamoto, Y.6
Eckmann, L.7
Dhungana, S.8
Pathmasiri, W.9
Sumner, S.10
Westwater, C.11
Brenner, D.A.12
Schnabl, B.13
-
68
-
-
79955606197
-
Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma
-
quiz 1108-1109.
-
McLoughlin RM, Mills KH (2011) Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma. J Allergy Clin Immunol 127:1097-1107; quiz 1108-1109.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1097-1107
-
-
McLoughlin, R.M.1
Mills, K.H.2
-
69
-
-
0035318251
-
Genetic determinants of ethanol-induced liver damage
-
Monzoni A, Masutti F, Saccoccio G, Bellentani S, Tiribelli C, Giacca M (2001) Genetic determinants of ethanol-induced liver damage. Mol Med 7:255-262.
-
(2001)
Mol Med
, vol.7
, pp. 255-262
-
-
Monzoni, A.1
Masutti, F.2
Saccoccio, G.3
Bellentani, S.4
Tiribelli, C.5
Giacca, M.6
-
70
-
-
70349335851
-
Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats
-
Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P (2009) Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Alcohol Clin Exp Res 33:1836-1846.
-
(2009)
Alcohol Clin Exp Res
, vol.33
, pp. 1836-1846
-
-
Mutlu, E.1
Keshavarzian, A.2
Engen, P.3
Forsyth, C.B.4
Sikaroodi, M.5
Gillevet, P.6
-
71
-
-
84860515098
-
Colonic microbiome is altered in alcoholism
-
Mutlu EA, Gillevet PM, Rangwala H, Sikaroodi M, Naqvi A, Engen PA, Kwasny M, Lau CK, Keshavarzian A (2012) Colonic microbiome is altered in alcoholism. Am J Physiol Gastrointest Liver Physiol 302:G966-G978.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
, pp. G966-G978
-
-
Mutlu, E.A.1
Gillevet, P.M.2
Rangwala, H.3
Sikaroodi, M.4
Naqvi, A.5
Engen, P.A.6
Kwasny, M.7
Lau, C.K.8
Keshavarzian, A.9
-
72
-
-
0027404469
-
Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2
-
Nanji AA, Khettry U, Sadrzadeh SM, Yamanaka T (1993) Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. Am J Pathol 142:367-373.
-
(1993)
Am J Pathol
, vol.142
, pp. 367-373
-
-
Nanji, A.A.1
Khettry, U.2
Sadrzadeh, S.M.3
Yamanaka, T.4
-
73
-
-
0029099274
-
Dietary saturated fatty acids: a novel treatment for alcoholic liver disease
-
Nanji AA, Sadrzadeh SM, Yang EK, Fogt F, Meydani M, Dannenberg AJ (1995) Dietary saturated fatty acids: a novel treatment for alcoholic liver disease. Gastroenterology 109:547-554.
-
(1995)
Gastroenterology
, vol.109
, pp. 547-554
-
-
Nanji, A.A.1
Sadrzadeh, S.M.2
Yang, E.K.3
Fogt, F.4
Meydani, M.5
Dannenberg, A.J.6
-
74
-
-
0030665615
-
Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat
-
Nanji AA, Zakim D, Rahemtulla A, Daly T, Miao L, Zhao S, Khwaja S, Tahan SR, Dannenberg AJ (1997) Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat. Hepatology 26:1538-1545.
-
(1997)
Hepatology
, vol.26
, pp. 1538-1545
-
-
Nanji, A.A.1
Zakim, D.2
Rahemtulla, A.3
Daly, T.4
Miao, L.5
Zhao, S.6
Khwaja, S.7
Tahan, S.R.8
Dannenberg, A.J.9
-
76
-
-
0342699553
-
Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease
-
Parlesak A, Schafer C, Schutz T, Bode JC, Bode C (2000) Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease. J Hepatol 32:742-747.
-
(2000)
J Hepatol
, vol.32
, pp. 742-747
-
-
Parlesak, A.1
Schafer, C.2
Schutz, T.3
Bode, J.C.4
Bode, C.5
-
77
-
-
46449126460
-
Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium
-
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR (2008) Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol 42:349-361.
-
(2008)
Alcohol
, vol.42
, pp. 349-361
-
-
Purohit, V.1
Bode, J.C.2
Bode, C.3
Brenner, D.A.4
Choudhry, M.A.5
Hamilton, F.6
Kang, Y.J.7
Keshavarzian, A.8
Rao, R.9
Sartor, R.B.10
Swanson, C.11
Turner, J.R.12
-
78
-
-
0020539554
-
Hepatic secretion of bilirubin and biliary lipids in patients with alcoholic cirrhosis of the liver
-
Raedsch R, Stiehl A, Gundert-Remy U, Walker S, Sieg A, Czygan P, Kommerell B (1983) Hepatic secretion of bilirubin and biliary lipids in patients with alcoholic cirrhosis of the liver. Digestion 26:80-88.
-
(1983)
Digestion
, vol.26
, pp. 80-88
-
-
Raedsch, R.1
Stiehl, A.2
Gundert-Remy, U.3
Walker, S.4
Sieg, A.5
Czygan, P.6
Kommerell, B.7
-
79
-
-
0031761303
-
Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer
-
Rao RK (1998) Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Alcohol Clin Exp Res 22:1724-1730.
-
(1998)
Alcohol Clin Exp Res
, vol.22
, pp. 1724-1730
-
-
Rao, R.K.1
-
81
-
-
1842425830
-
Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition
-
Ronis MJ, Korourian S, Zipperman M, Hakkak R, Badger TM (2004) Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition. J Nutr 134:904-912.
-
(2004)
J Nutr
, vol.134
, pp. 904-912
-
-
Ronis, M.J.1
Korourian, S.2
Zipperman, M.3
Hakkak, R.4
Badger, T.M.5
-
82
-
-
33645327743
-
Role of intestinal bacterial overgrowth and intestinal motility in bacterial translocation in experimental cirrhosis
-
Sanchez E, Casafont F, Guerra A, De Benito I, Pons-Romero F (2005) Role of intestinal bacterial overgrowth and intestinal motility in bacterial translocation in experimental cirrhosis. Rev Esp Enferm Dig 97:805-814.
-
(2005)
Rev Esp Enferm Dig
, vol.97
, pp. 805-814
-
-
Sanchez, E.1
Casafont, F.2
Guerra, A.3
De Benito, I.4
Pons-Romero, F.5
-
83
-
-
0034965118
-
Sex difference in alcohol-related organ injury
-
Sato N, Lindros KO, Baraona E, Ikejima K, Mezey E, Jarvelainen HA, Ramchandani VA (2001) Sex difference in alcohol-related organ injury. Alcohol Clin Exp Res 25:40S-45S.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 40S-45S
-
-
Sato, N.1
Lindros, K.O.2
Baraona, E.3
Ikejima, K.4
Mezey, E.5
Jarvelainen, H.A.6
Ramchandani, V.A.7
-
84
-
-
84898824175
-
Interactions between the intestinal microbiome and liver diseases
-
Schnabl B, Brenner DA (2014) Interactions between the intestinal microbiome and liver diseases. Gastroenterology 146:1513-1524.
-
(2014)
Gastroenterology
, vol.146
, pp. 1513-1524
-
-
Schnabl, B.1
Brenner, D.A.2
-
85
-
-
84856350648
-
Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut
-
Seki E, Schnabl B (2012) Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut. J Physiol 590:447-458.
-
(2012)
J Physiol
, vol.590
, pp. 447-458
-
-
Seki, E.1
Schnabl, B.2
-
86
-
-
0027441084
-
A syndrome of cirrhosis, achlorhydria, small intestinal bacterial overgrowth, and fat malabsorption
-
Shindo K, Machida M, Miyakawa K, Fukumura M (1993) A syndrome of cirrhosis, achlorhydria, small intestinal bacterial overgrowth, and fat malabsorption. Am J Gastroenterol 88:2084-2091.
-
(1993)
Am J Gastroenterol
, vol.88
, pp. 2084-2091
-
-
Shindo, K.1
Machida, M.2
Miyakawa, K.3
Fukumura, M.4
-
87
-
-
33144476425
-
Use and abuse of hydrogen breath tests
-
Simren M, Stotzer PO (2006) Use and abuse of hydrogen breath tests. Gut 55:297-303.
-
(2006)
Gut
, vol.55
, pp. 297-303
-
-
Simren, M.1
Stotzer, P.O.2
-
88
-
-
84922868050
-
Gut-liver axis in alcoholic liver disease
-
Szabo G (2015) Gut-liver axis in alcoholic liver disease. Gastroenterology 148:30-36.
-
(2015)
Gastroenterology
, vol.148
, pp. 30-36
-
-
Szabo, G.1
-
89
-
-
0036708852
-
Bacterial translocation and peptidoglycan translocation by acute ethanol administration
-
Tabata T, Tani T, Endo Y, Hanasawa K (2002) Bacterial translocation and peptidoglycan translocation by acute ethanol administration. J Gastroenterol 37:726-731.
-
(2002)
J Gastroenterol
, vol.37
, pp. 726-731
-
-
Tabata, T.1
Tani, T.2
Endo, Y.3
Hanasawa, K.4
-
90
-
-
0034073962
-
Effect of acute ethanol administration on the intestinal absorption of endotoxin in rats
-
Tamai H, Kato S, Horie Y, Ohki E, Yokoyama H, Ishii H (2000) Effect of acute ethanol administration on the intestinal absorption of endotoxin in rats. Alcohol Clin Exp Res 24:390-394.
-
(2000)
Alcohol Clin Exp Res
, vol.24
, pp. 390-394
-
-
Tamai, H.1
Kato, S.2
Horie, Y.3
Ohki, E.4
Yokoyama, H.5
Ishii, H.6
-
91
-
-
66749123764
-
Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damage
-
Tang Y, Forsyth CB, Farhadi A, Rangan J, Jakate S, Shaikh M, Banan A, Fields JZ, Keshavarzian A (2009) Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damage. Alcohol Clin Exp Res 33:1220-1230.
-
(2009)
Alcohol Clin Exp Res
, vol.33
, pp. 1220-1230
-
-
Tang, Y.1
Forsyth, C.B.2
Farhadi, A.3
Rangan, J.4
Jakate, S.5
Shaikh, M.6
Banan, A.7
Fields, J.Z.8
Keshavarzian, A.9
-
92
-
-
0033630511
-
Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids
-
Theisen J, Nehra D, Citron D, Johansson J, Hagen JA, Crookes PF, Demeester SR, Bremner CG, Demeester TR, Peters JH (2000) Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J Gastrointest Surg 4:50-54.
-
(2000)
J Gastrointest Surg
, vol.4
, pp. 50-54
-
-
Theisen, J.1
Nehra, D.2
Citron, D.3
Johansson, J.4
Hagen, J.A.5
Crookes, P.F.6
Demeester, S.R.7
Bremner, C.G.8
Demeester, T.R.9
Peters, J.H.10
-
93
-
-
73349111259
-
Variant in PNPLA3 is associated with alcoholic liver disease
-
Tian C, Stokowski RP, Kershenobich D, Ballinger DG, Hinds DA (2010) Variant in PNPLA3 is associated with alcoholic liver disease. Nat Genet 42:21-23.
-
(2010)
Nat Genet
, vol.42
, pp. 21-23
-
-
Tian, C.1
Stokowski, R.P.2
Kershenobich, D.3
Ballinger, D.G.4
Hinds, D.A.5
-
94
-
-
0034950477
-
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
-
Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG (2001) Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 34:101-108.
-
(2001)
Hepatology
, vol.34
, pp. 101-108
-
-
Uesugi, T.1
Froh, M.2
Arteel, G.E.3
Bradford, B.U.4
Thurman, R.G.5
-
95
-
-
84890614712
-
Veillonella, Firmicutes: microbes disguised as Gram negatives
-
Vesth T, Ozen A, Andersen SC, Kaas RS, Lukjancenko O, Bohlin J, Nookaew I, Wassenaar TM, Ussery DW (2013) Veillonella, Firmicutes: microbes disguised as Gram negatives. Stand Genomic Sci 9:431-448.
-
(2013)
Stand Genomic Sci
, vol.9
, pp. 431-448
-
-
Vesth, T.1
Ozen, A.2
Andersen, S.C.3
Kaas, R.S.4
Lukjancenko, O.5
Bohlin, J.6
Nookaew, I.7
Wassenaar, T.M.8
Ussery, D.W.9
-
96
-
-
84883395327
-
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption
-
Xie G, Zhong W, Li H, Li Q, Qiu Y, Zheng X, Chen H, Zhao X, Zhang S, Zhou Z, Zeisel SH, Jia W (2013a) Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J 27:3583-3593.
-
(2013)
FASEB J
, vol.27
, pp. 3583-3593
-
-
Xie, G.1
Zhong, W.2
Li, H.3
Li, Q.4
Qiu, Y.5
Zheng, X.6
Chen, H.7
Zhao, X.8
Zhang, S.9
Zhou, Z.10
Zeisel, S.H.11
Jia, W.12
-
97
-
-
84879952841
-
Chronic ethanol consumption alters mammalian gastrointestinal content metabolites
-
Xie G, Zhong W, Zheng X, Li Q, Qiu Y, Li H, Chen H, Zhou Z, Jia W (2013b) Chronic ethanol consumption alters mammalian gastrointestinal content metabolites. J Proteome Res 12:3297-3306.
-
(2013)
J Proteome Res
, vol.12
, pp. 3297-3306
-
-
Xie, G.1
Zhong, W.2
Zheng, X.3
Li, Q.4
Qiu, Y.5
Li, H.6
Chen, H.7
Zhou, Z.8
Jia, W.9
-
98
-
-
84860389258
-
Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK
-
Xu J, Lai KK, Verlinsky A, Lugea A, French SW, Cooper MP, Ji C, Tsukamoto H (2011) Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK. J Hepatol 55:673-682.
-
(2011)
J Hepatol
, vol.55
, pp. 673-682
-
-
Xu, J.1
Lai, K.K.2
Verlinsky, A.3
Lugea, A.4
French, S.W.5
Cooper, M.P.6
Ji, C.7
Tsukamoto, H.8
-
99
-
-
78751537350
-
Enteric dysbiosis associated with a mouse model of alcoholic liver disease
-
Yan AW, Fouts DE, Brandl J, Starkel P, Torralba M, Schott E, Tsukamoto H, Nelson KE, Brenner DA, Schnabl B (2011) Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Hepatology 53:96-105.
-
(2011)
Hepatology
, vol.53
, pp. 96-105
-
-
Yan, A.W.1
Fouts, D.E.2
Brandl, J.3
Starkel, P.4
Torralba, M.5
Schott, E.6
Tsukamoto, H.7
Nelson, K.E.8
Brenner, D.A.9
Schnabl, B.10
-
100
-
-
0035313376
-
Reduced early alcohol-induced liver injury in CD14-deficient mice
-
Yin M, Bradford BU, Wheeler MD, Uesugi T, Froh M, Goyert SM, Thurman RG (2001) Reduced early alcohol-induced liver injury in CD14-deficient mice. J Immunol 166:4737-4742.
-
(2001)
J Immunol
, vol.166
, pp. 4737-4742
-
-
Yin, M.1
Bradford, B.U.2
Wheeler, M.D.3
Uesugi, T.4
Froh, M.5
Goyert, S.M.6
Thurman, R.G.7
-
101
-
-
24144496133
-
Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice
-
You M, Considine RV, Leone TC, Kelly DP, Crabb DW (2005) Role of adiponectin in the protective action of dietary saturated fat against alcoholic fatty liver in mice. Hepatology 42:568-577.
-
(2005)
Hepatology
, vol.42
, pp. 568-577
-
-
You, M.1
Considine, R.V.2
Leone, T.C.3
Kelly, D.P.4
Crabb, D.W.5
-
102
-
-
2342640188
-
Intestinal microflora in patients with liver cirrhosis
-
Zhao HY, Wang HJ, Lu Z, Xu SZ (2004) Intestinal microflora in patients with liver cirrhosis. Chin J Dig Dis 5:64-67.
-
(2004)
Chin J Dig Dis
, vol.5
, pp. 64-67
-
-
Zhao, H.Y.1
Wang, H.J.2
Lu, Z.3
Xu, S.Z.4
-
103
-
-
84890376379
-
Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats
-
Zhong W, Li Q, Xie G, Sun X, Tan X, Jia W, Zhou Z (2013) Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats. Am J Physiol Gastrointest Liver Physiol 305:G919-G932.
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.305
, pp. G919-G932
-
-
Zhong, W.1
Li, Q.2
Xie, G.3
Sun, X.4
Tan, X.5
Jia, W.6
Zhou, Z.7
|