-
1
-
-
72149125838
-
The transcellular spread of cytosolic amyloids, prions, and prionoids
-
Aguzzi, A., and Rajendran, L. (2009). The transcellular spread of cytosolic amyloids, prions, and prionoids. Neuron 64, 783-790. doi: 10.1016/j.neuron.2009.12.016
-
(2009)
Neuron
, vol.64
, pp. 783-790
-
-
Aguzzi, A.1
Rajendran, L.2
-
2
-
-
77957375690
-
Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene
-
Alzualde, A., Moreno, F., Martínez-Lage, P., Ferrer, I., Gorostidi, A., Otaegui, D., et al. (2010). Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B, 1283-1291. doi: 10.1002/ajmg.b.31099
-
(2010)
Am. J. Med. Genet. B Neuropsychiatr. Genet
, vol.153B
, pp. 1283-1291
-
-
Alzualde, A.1
Moreno, F.2
Martínez-Lage, P.3
Ferrer, I.4
Gorostidi, A.5
Otaegui, D.6
-
3
-
-
4143139576
-
APOE genotype effects on Alzheimer's disease onset and epidemiology
-
Ashford, J. W. (2004). APOE genotype effects on Alzheimer's disease onset and epidemiology. J. Mol. Neurosci. 23, 157-165. doi: 10.1385/JMN:23:3:157
-
(2004)
J. Mol. Neurosci
, vol.23
, pp. 157-165
-
-
Ashford, J.W.1
-
4
-
-
84866530316
-
Role of genes linked to sporadic Alzheimer's disease risk in the production of β-amyloid peptides
-
Bali, J., Gheinani, A. H., Zurbriggen, S., and Rajendran, L. (2012). Role of genes linked to sporadic Alzheimer's disease risk in the production of β-amyloid peptides. Proc. Natl. Acad. Sci. U.S.A. 109, 15307-15311. doi: 10.1073/pnas.1201632109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 15307-15311
-
-
Bali, J.1
Gheinani, A.H.2
Zurbriggen, S.3
Rajendran, L.4
-
5
-
-
4544322045
-
Free radicals and aging
-
Barja, G. (2004). Free radicals and aging. Trends Neurosci. 27, 595-600. doi: 10.1016/j.tins.2004.07.005
-
(2004)
Trends Neurosci
, vol.27
, pp. 595-600
-
-
Barja, G.1
-
6
-
-
3042856300
-
Somatic and germline mosaicism in sporadic early-onset Alzheimer's disease
-
Beck, J. A., Poulter, M., Campbell, T. A., Uphill, J. B., Adamson, G., Geddes, J. F., et al. (2004). Somatic and germline mosaicism in sporadic early-onset Alzheimer's disease. Hum. Mol. Genet. 13, 1219-1224. doi: 10.1093/hmg/ddh134
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 1219-1224
-
-
Beck, J.A.1
Poulter, M.2
Campbell, T.A.3
Uphill, J.B.4
Adamson, G.5
Geddes, J.F.6
-
7
-
-
84903366979
-
Missense variant in TREML2 protects against Alzheimer's disease
-
Benitez, B. A., Jin, S. C., Guerreiro, R., Graham, R., Lord, J., Harold, D., et al. (2014). Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol. Aging 35, 1510. doi: 10.1016/j.neurobiolaging.2013.12.010
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1510
-
-
Benitez, B.A.1
Jin, S.C.2
Guerreiro, R.3
Graham, R.4
Lord, J.5
Harold, D.6
-
8
-
-
79952787104
-
"Early-Onset Familial Alzheimer Disease,"
-
eds R. A. Pagon, M. P. Adam, H. H. Ardinger, T. D. Bird, C. R. Dolan, and C. T. Fong (Seattle, WA; University of Washington, Seattle)
-
® [Internet], eds R. A. Pagon, M. P. Adam, H. H. Ardinger, T. D. Bird, C. R. Dolan, and C. T. Fong (Seattle, WA; University of Washington, Seattle), 1993-2014.
-
(1999)
® [Internet]
, pp. 1993-2014
-
-
Bird, T.D.1
-
9
-
-
38349138030
-
Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease
-
Blom, E. S., Viswanathan, J., Kilander, L., Helisalmi, S., Soininen, H., Lannfelt, L., et al. (2008). Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease. Eur. J. Hum. Genet. 16, 171-175. doi: 10.1038/sj.ejhg.5201966
-
(2008)
Eur. J. Hum. Genet
, vol.16
, pp. 171-175
-
-
Blom, E.S.1
Viswanathan, J.2
Kilander, L.3
Helisalmi, S.4
Soininen, H.5
Lannfelt, L.6
-
10
-
-
84872314298
-
Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease
-
Bullock, J. M., Medway, C., Cortina-Borja, M., Turton, J. C., Prince, J. A., Ibrahim-Verbaas, C. A., et al. (2013). Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiol. Aging 34, 1309.e1-1309.e7. doi: 10.1016/j.neurobiolaging.2012.08.010
-
(2013)
Neurobiol. Aging
, vol.34
-
-
Bullock, J.M.1
Medway, C.2
Cortina-Borja, M.3
Turton, J.C.4
Prince, J.A.5
Ibrahim-Verbaas, C.A.6
-
11
-
-
79960629063
-
Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases
-
Calero, O., Bullido, M. J., Clarimón, J., Frank-García, A., Martínez-Martín, P., Lleó, A., et al. (2011). Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases. PLoS ONE 6:e22090. doi: 10.1371/journal.pone.0022090
-
(2011)
PLoS ONE
, vol.6
-
-
Calero, O.1
Bullido, M.J.2
Clarimón, J.3
Frank-García, A.4
Martínez-Martín, P.5
Lleó, A.6
-
12
-
-
33744478880
-
Endophenotypes in the genetic analyses of mental disorders
-
Cannon, T. D., and Keller, M. C. (2006). Endophenotypes in the genetic analyses of mental disorders. Annu. Rev. Clin. Psychol. 2, 267-290. doi: 10.1146/annurev.clinpsy.2.022305.095232
-
(2006)
Annu. Rev. Clin. Psychol
, vol.2
, pp. 267-290
-
-
Cannon, T.D.1
Keller, M.C.2
-
13
-
-
84899907308
-
Exome array study did not identify novel variants in Alzheimer's disease
-
Chung, S. J., Kim, M. J., Kim, J., Kim, Y. J., You, S., Koh, J., et al. (2014). Exome array study did not identify novel variants in Alzheimer's disease. Neurobiol. Aging 35, 1958.e13-1958.e14. doi: 10.1016/j.neurobiolaging.2014.03.007
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Chung, S.J.1
Kim, M.J.2
Kim, J.3
Kim, Y.J.4
You, S.5
Koh, J.6
-
14
-
-
67650470272
-
Epistasis in sporadic Alzheimer's disease
-
Combarros, O., Cortina-Borja, M., Smith, A. D., and Lehmann, D. J. (2009). Epistasis in sporadic Alzheimer's disease. Neurobiol. Aging 30, 1333-1349. doi: 10.1016/j.neurobiolaging.2007.11.027
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 1333-1349
-
-
Combarros, O.1
Cortina-Borja, M.2
Smith, A.D.3
Lehmann, D.J.4
-
15
-
-
67349166946
-
Detecting gene-gene interactions that underlie human diseases
-
Cordell, H. J. (2009). Detecting gene-gene interactions that underlie human diseases. Nat. Rev. Genet. 10, 392-404. doi: 10.1038/nrg2579
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 392-404
-
-
Cordell, H.J.1
-
16
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
Corder, E. H., Saunders, A. M., Risch, N. J., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C. Jr., et al. (1994). Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat. Genet. 7, 180-184. doi: 10.1038/ng0694-180
-
(1994)
Nat. Genet
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
Schmechel, D.E.5
Gaskell, P.C.6
-
17
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., et al. (1993). Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923. doi: 10.1126/science.8346443
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
-
18
-
-
84892819277
-
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease
-
Cruchaga, C., Karch, C. M., Jin, S. C., Benitez, B. A., Cai, Y., Guerreiro, R., et al. (2014). Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature 505, 550-554. doi: 10.1038/nature12825
-
(2014)
Nature
, vol.505
, pp. 550-554
-
-
Cruchaga, C.1
Karch, C.M.2
Jin, S.C.3
Benitez, B.A.4
Cai, Y.5
Guerreiro, R.6
-
19
-
-
84889590173
-
Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
-
Cuyvers, E., Bettens, K., Philtjens, S., Van Langenhove, T., Gijselinck, I., van der Zee, J., et al. (2014). Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia. Neurobiol. Aging 35, 726.e11-726.e19. doi: 10.1016/j.neurobiolaging.2013.09.009
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Cuyvers, E.1
Bettens, K.2
Philtjens, S.3
Van Langenhove, T.4
Gijselinck, I.5
van der Zee, J.6
-
20
-
-
62449330486
-
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis
-
Di Fede, G., Catania, M., Morbin, M., Rossi, G., Suardi, S., Mazzoleni, G., et al. (2009). A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science 323, 1473-1477. doi: 10.1126/science.1168979
-
(2009)
Science
, vol.323
, pp. 1473-1477
-
-
Di Fede, G.1
Catania, M.2
Morbin, M.3
Rossi, G.4
Suardi, S.5
Mazzoleni, G.6
-
21
-
-
77956130453
-
Worldwide allele frequencies of the human apolipoprotein E gene: Climate, local adaptations, and evolutionary history
-
Eisenberg, D. T., Kuzawa, C. W., and Hayes, M. G. (2010). Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history. Am. J. Phys. Anthropol. 143, 100-111. doi: 10.1002/ajpa.21298
-
(2010)
Am. J. Phys. Anthropol
, vol.143
, pp. 100-111
-
-
Eisenberg, D.T.1
Kuzawa, C.W.2
Hayes, M.G.3
-
22
-
-
77953647392
-
A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR)
-
Frade, J. M., and López-Sánchez, N. (2010). A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR). Cell Cycle 9, 1934-1941. doi: 10.4161/cc.9.10.11582
-
(2010)
Cell Cycle
, vol.9
, pp. 1934-1941
-
-
Frade, J.M.1
López-Sánchez, N.2
-
23
-
-
84903711600
-
Similarities and differences between exome sequences found in a variety of tissues from the same individual
-
Gómez-Ramos, A., Sanchez-Sanchez, R., Muhaisen, A., Rábano, A., Soriano, E., and Avila, J. (2014). Similarities and differences between exome sequences found in a variety of tissues from the same individual. PLoS ONE 9:e101412. doi: 10.1371/journal.pone.0101412
-
(2014)
PLoS ONE
, vol.9
-
-
Gómez-Ramos, A.1
Sanchez-Sanchez, R.2
Muhaisen, A.3
Rábano, A.4
Soriano, E.5
Avila, J.6
-
24
-
-
84887963698
-
SnapShot: Genetics of Alzheimer's disease
-
Guerreiro, R., Brás, J., and Hardy, J. (2013a). SnapShot: genetics of Alzheimer's disease. Cell 155, 968-968. doi: 10.1016/j.cell.2013.10.037
-
(2013)
Cell
, vol.155
-
-
Guerreiro, R.1
Brás, J.2
Hardy, J.3
-
25
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., et al. (2013b). TREM2 variants in Alzheimer's disease. N. Engl. J. Med. 368, 117-127. doi: 10.1056/NEJMoa1211851
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
-
26
-
-
84922916943
-
A nonsense mutation in PRNP associated with clinical Alzheimer's disease
-
Guerreiro, R., Brás, J., Wojtas, A., Rademakers, R., Hardy, J., and Graff-Radford, N. (2014). A nonsense mutation in PRNP associated with clinical Alzheimer's disease. Neurobiol. Aging 35, 2656.e13-2656.e16. doi: 10.1016/j.neurobiolaging.2014.05.013
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Guerreiro, R.1
Brás, J.2
Wojtas, A.3
Rademakers, R.4
Hardy, J.5
Graff-Radford, N.6
-
27
-
-
84855819016
-
The genetic architecture of Alzheimer's disease: Beyond APP, PSENs and APOE
-
Guerreiro, R. J., Gustafson, D. R., and Hardy, J. (2012). The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE. Neurobiol. Aging 33, 437-456. doi: 10.1016/j.neurobiolaging.2010.03.025
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 437-456
-
-
Guerreiro, R.J.1
Gustafson, D.R.2
Hardy, J.3
-
28
-
-
84885761556
-
TREM2 and neurodegenerative disease
-
Guerreiro, R., and Hardy, J. (2013). TREM2 and neurodegenerative disease. N. Engl. J. Med. 369, 1569-1570. doi: 10.1056/NEJMc1306509#SA1
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 1569-1570
-
-
Guerreiro, R.1
Hardy, J.2
-
29
-
-
84922938637
-
Genome-wide association interaction analysis for Alzheimer's disease
-
Gusareva, E. S., Carrasquillo, M. M., Bellenguez, C., Cuyvers, E., Colon, S., Graff-Radford, N. R., et al. (2014). Genome-wide association interaction analysis for Alzheimer's disease. Neurobiol. Aging 35, 2436-2443. doi: 10.1016/j.neurobiolaging.2014.05.014
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 2436-2443
-
-
Gusareva, E.S.1
Carrasquillo, M.M.2
Bellenguez, C.3
Cuyvers, E.4
Colon, S.5
Graff-Radford, N.R.6
-
30
-
-
84931070277
-
Down syndrome and Alzheimer's disease: Common pathways, common goals
-
[Epub ahead of print]
-
Hartley, D., Blumenthal, T., Carrillo, M., DiPaolo, G., Esralew, L., Gardiner, K.et al. (2014). Down syndrome and Alzheimer's disease: common pathways, common goals. Alzheimers Dement. doi: 10.1016/j.jalz.2014.10.007 [Epub ahead of print].
-
(2014)
Alzheimers Dement
-
-
Hartley, D.1
Blumenthal, T.2
Carrillo, M.3
DiPaolo, G.4
Esralew, L.5
Gardiner, K.6
-
31
-
-
0035135490
-
Limited somatic mosaicism for Friedreich's ataxia GAA triplet repeat expansions identified by small pool PCR in blood leukocytes
-
Hellenbroich, Y., Schwinger, E., and Zühlke, C. (2001). Limited somatic mosaicism for Friedreich's ataxia GAA triplet repeat expansions identified by small pool PCR in blood leukocytes. Acta Neurol. Scand. 103, 188-192. doi: 10.1034/j.1600-0404.2001.103003188.x
-
(2001)
Acta Neurol. Scand
, vol.103
, pp. 188-192
-
-
Hellenbroich, Y.1
Schwinger, E.2
Zühlke, C.3
-
32
-
-
84894094478
-
Epistatic genetic effects among Alzheimer's candidate genes
-
Hohman, T. J., Koran, M. E., Thornton-Wells, T., and Alzheimer's Neuroimaging Initiative. (2013). Epistatic genetic effects among Alzheimer's candidate genes. PLoS ONE 8:e80839. doi: 10.1371/journal.pone.0080839
-
(2013)
PLoS ONE
, vol.8
-
-
Hohman, T.J.1
Koran, M.E.2
Thornton-Wells, T.3
Alzheimer's Neuroimaging Initiative4
-
33
-
-
64449088956
-
Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning
-
Iourov, I. Y., Vorsanova, S. G., Liehr, T., and Yurov, Y. B. (2009). Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: differential expression and pathological meaning. Neurobiol. Dis. 34, 212-220. doi: 10.1016/j.nbd.2009.01.003
-
(2009)
Neurobiol. Dis
, vol.34
, pp. 212-220
-
-
Iourov, I.Y.1
Vorsanova, S.G.2
Liehr, T.3
Yurov, Y.B.4
-
34
-
-
84877578202
-
Somatic cell genomics of brain disorders: A new opportunity to clarify genetic-environmental interactions
-
Iourov, I. Y., Vorsanova, S. G., and Yurov, Y. B. (2013). Somatic cell genomics of brain disorders: a new opportunity to clarify genetic-environmental interactions. Cytogenet. Genome. Res. 139, 181-188. doi: 10.1159/000347053
-
(2013)
Cytogenet. Genome. Res
, vol.139
, pp. 181-188
-
-
Iourov, I.Y.1
Vorsanova, S.G.2
Yurov, Y.B.3
-
35
-
-
84861628224
-
Detectable clonal mosaicism and its relationship to aging and cancer
-
Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., et al. (2012). Detectable clonal mosaicism and its relationship to aging and cancer. Nat. Genet. 44, 651-658. doi: 10.1038/ng.2270
-
(2012)
Nat. Genet
, vol.44
, pp. 651-658
-
-
Jacobs, K.B.1
Yeager, M.2
Zhou, W.3
Wacholder, S.4
Wang, Z.5
Rodriguez-Santiago, B.6
-
36
-
-
79956205888
-
DNA repair deficiency in neurodegeneration
-
Jeppesen, D. K., Bohr, V. A., and Stevnsner, T. (2011). DNA repair deficiency in neurodegeneration. Prog. Neurobiol. 94, 166-200. doi: 10.1016/j.pneurobio.2011.04.013
-
(2011)
Prog. Neurobiol
, vol.94
, pp. 166-200
-
-
Jeppesen, D.K.1
Bohr, V.A.2
Stevnsner, T.3
-
37
-
-
84868030363
-
Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort
-
Jin, S. C., Pastor, P., Cooper, B., Cervantes, S., Benitez, B. A., Razquin, C., et al. (2012). Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort. Alzheimers Res. Ther. 4, 34. doi: 10.1186/alzrt137
-
(2012)
Alzheimers Res. Ther
, vol.4
, pp. 34
-
-
Jin, S.C.1
Pastor, P.2
Cooper, B.3
Cervantes, S.4
Benitez, B.A.5
Razquin, C.6
-
38
-
-
84864471159
-
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
-
Jonsson, T., Atwal, J. K., Steinberg, S., Snaedal, J., Jonsson, P. V., Bjornsson, S., et al. (2012). A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 488, 96-99. doi: 10.1038/nature11283
-
(2012)
Nature
, vol.488
, pp. 96-99
-
-
Jonsson, T.1
Atwal, J.K.2
Steinberg, S.3
Snaedal, J.4
Jonsson, P.V.5
Bjornsson, S.6
-
39
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
Jonsson, T., Stefansson, H., Steinberg, S., Jonsdottir, I., Jonsson, P. V., Snaedal, J., et al. (2013). Variant of TREM2 associated with the risk of Alzheimer's disease. N. Engl. J. Med. 368, 107-116. doi: 10.1056/NEJMoa1211103
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
-
40
-
-
0034625562
-
The expanded CAG repeat associated with juvenile Huntington disease shows a common origin of most or all neurons and glia in human cerebrum
-
Kahlem, P., and Djian, P. (2000). The expanded CAG repeat associated with juvenile Huntington disease shows a common origin of most or all neurons and glia in human cerebrum. Neurosci. Lett. 286, 203-207. doi: 10.1016/S0304-3940(00)01029-6
-
(2000)
Neurosci. Lett
, vol.286
, pp. 203-207
-
-
Kahlem, P.1
Djian, P.2
-
41
-
-
84903627137
-
Alzheimer's disease genetics: From the bench to the clinic
-
Karch, C. M., Cruchaga, C., and Goate, A. M. (2014). Alzheimer's disease genetics: from the bench to the clinic. Neuron 83, 11-26. doi: 10.1016/j.neuron.2014.05.041
-
(2014)
Neuron
, vol.83
, pp. 11-26
-
-
Karch, C.M.1
Cruchaga, C.2
Goate, A.M.3
-
42
-
-
84920703987
-
Alzheimer's disease risk genes and mechanisms of disease pathogenesis
-
Karch, C. M., and Goate, A. M. (2015). Alzheimer's disease risk genes and mechanisms of disease pathogenesis. Biol. Psychiatry 77, 43-51. doi: 10.1016/j.biopsych.2014.05.006
-
(2015)
Biol. Psychiatry
, vol.77
, pp. 43-51
-
-
Karch, C.M.1
Goate, A.M.2
-
43
-
-
69449108391
-
Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease
-
Kasuga, K., Shimohata, T., Nishimura, A., Shiga, A., Mizuguchi, T., Tokunaga, J., et al. (2009). Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease. J. Neurol. Neurosurg. Psychiatry 80, 1050-1052. doi: 10.1136/jnnp.2008.161703
-
(2009)
J. Neurol. Neurosurg. Psychiatry
, vol.80
, pp. 1050-1052
-
-
Kasuga, K.1
Shimohata, T.2
Nishimura, A.3
Shiga, A.4
Mizuguchi, T.5
Tokunaga, J.6
-
44
-
-
84908311475
-
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: Significant associations with proteins involved in amyloid processing and inflammation
-
Kauwe, J. S., Bailey, M. H., Ridge, P. G., Perry, R., Wadsworth, M. E., Hoyt, K. L., et al. (2014). Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation. PLoS Genet. 10:e1004758. doi: 10.1371/journal.pgen.1004758
-
(2014)
PLoS Genet
, vol.10
-
-
Kauwe, J.S.1
Bailey, M.H.2
Ridge, P.G.3
Perry, R.4
Wadsworth, M.E.5
Hoyt, K.L.6
-
45
-
-
79951798741
-
Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease
-
Kauwe, J. S., Cruchaga, C., Karch, C. M., Sadler, B., Lee, M., Mayo, K., et al. (2011). Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease. PLoS ONE 6:e15918. doi: 10.1371/journal.pone.0015918
-
(2011)
PLoS ONE
, vol.6
-
-
Kauwe, J.S.1
Cruchaga, C.2
Karch, C.M.3
Sadler, B.4
Lee, M.5
Mayo, K.6
-
46
-
-
84860775115
-
Somatic mutations in aging, cancer and neurodegeneration
-
Kennedy, S. R., Loeb, L. A., and Herr, A. J. (2012). Somatic mutations in aging, cancer and neurodegeneration. Mech. Ageing Dev. 133, 118-126. doi: 10.1016/j.mad.2011.10.009
-
(2012)
Mech. Ageing Dev
, vol.133
, pp. 118-126
-
-
Kennedy, S.R.1
Loeb, L.A.2
Herr, A.J.3
-
47
-
-
70349569016
-
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity
-
Kim, M., Suh, J., Romano, D., Truong, M. H., Mullin, K., Hooli, B., et al. (2009). Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum. Mol. Genet. 18, 3987-3996. doi: 10.1093/hmg/ddp323
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 3987-3996
-
-
Kim, M.1
Suh, J.2
Romano, D.3
Truong, M.H.4
Mullin, K.5
Hooli, B.6
-
48
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert, J. C., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 45, 1452-1458. doi: 10.1038/ng.2802
-
(2013)
Nat. Genet
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
-
49
-
-
84903776641
-
Homozygous TREM2 mutation in a family with atypical frontotemporal dementia
-
Le Ber, I., De Septenville, A., Guerreiro, R., Bras, J., Camuzat, A., Caroppo, P., et al. (2014). Homozygous TREM2 mutation in a family with atypical frontotemporal dementia. Neurobiol. Aging 35, 2419.e23-2419.e25. doi: 10.1016/j.neurobiolaging.2014.04.010
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Le Ber, I.1
De Septenville, A.2
Guerreiro, R.3
Bras, J.4
Camuzat, A.5
Caroppo, P.6
-
50
-
-
84927590524
-
Disease-related mutations among Caribbean Hispanics with familial dementia
-
Lee, J. H., Kahn, A., Cheng, R., Reitz, C., Vardarajan, B., Lantigua, R., et al. (2014). Disease-related mutations among Caribbean Hispanics with familial dementia. Mol. Genet. Genomic Med. 2, 430-437. doi: 10.1002/mgg3.85
-
(2014)
Mol. Genet. Genomic Med
, vol.2
, pp. 430-437
-
-
Lee, J.H.1
Kahn, A.2
Cheng, R.3
Reitz, C.4
Vardarajan, B.5
Lantigua, R.6
-
51
-
-
81355123253
-
Transferrin and HFE genes interact in Alzheimer's disease risk: The Epistasis Project
-
Lehmann, D. J., Schuur, M., Warden, D. R., Hammond, N., Belbin, O., Kölsch, H., et al. (2012). Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiol. Aging 33, 202.e1-202.e13. doi: 10.1016/j.neurobiolaging.2010.07.018
-
(2012)
Neurobiol. Aging
, vol.33
-
-
Lehmann, D.J.1
Schuur, M.2
Warden, D.R.3
Hammond, N.4
Belbin, O.5
Kölsch, H.6
-
52
-
-
84927158295
-
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans
-
Logue, M. W., Schu, M., Vardarajan, B. N., Farrell, J., Bennett, D. A., Buxbaum, J. D., et al. (2014). Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans. Alzheimers Dement 10, 609-618. doi: 10.1016/j.jalz.2014.06.010
-
(2014)
Alzheimers Dement
, vol.10
, pp. 609-618
-
-
Logue, M.W.1
Schu, M.2
Vardarajan, B.N.3
Farrell, J.4
Bennett, D.A.5
Buxbaum, J.D.6
-
53
-
-
84917694860
-
Identification of rare variants in Alzheimer's disease
-
Lord, J., Lu, A. J., and Cruchaga, C. (2014). Identification of rare variants in Alzheimer's disease. Front. Genet. 5:369. doi: 10.3389/fgene.2014.00369
-
(2014)
Front. Genet
, vol.5
, pp. 369
-
-
Lord, J.1
Lu, A.J.2
Cruchaga, C.3
-
54
-
-
77955090647
-
Evolution of the mutation rate
-
Lynch, M. (2010). Evolution of the mutation rate. Trends Genet. 26, 345-352. doi: 10.1016/j.tig.2010.05.003
-
(2010)
Trends Genet
, vol.26
, pp. 345-352
-
-
Lynch, M.1
-
55
-
-
84874775052
-
Gene-based testing of interactions in association studies of quantitative traits
-
Ma, L., Clark, A. G., and Keinan, A. (2013). Gene-based testing of interactions in association studies of quantitative traits. PLoS Genet. 9:e1003321. doi: 10.1371/journal.pgen.1003321
-
(2013)
PLoS Genet
, vol.9
-
-
Ma, L.1
Clark, A.G.2
Keinan, A.3
-
56
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley, R. W. (1988). Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240, 622-630. doi: 10.1126/science.3283935
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
57
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., et al. (2009). Finding the missing heritability of complex diseases. Nature 461, 747-753. doi: 10.1038/nature08494
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
-
59
-
-
0038771182
-
RIPped out by presenilin-dependent gamma-secretase
-
Medina, M., and Dotti, C. G. (2003). RIPped out by presenilin-dependent gamma-secretase. Cell. Signal. 15, 829-841. doi: 10.1016/S0898-6568(03)00041-X
-
(2003)
Cell. Signal
, vol.15
, pp. 829-841
-
-
Medina, M.1
Dotti, C.G.2
-
60
-
-
78650706363
-
Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice
-
Møllersen, L., Rowe, A. D., Larsen, E., Rognes, T., and Klungland, A. (2010). Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice. PLoS Genet. 6:e1001242. doi: 10.1371/journal.pgen.1001242
-
(2010)
PLoS Genet
, vol.6
-
-
Møllersen, L.1
Rowe, A.D.2
Larsen, E.3
Rognes, T.4
Klungland, A.5
-
61
-
-
84872333268
-
A novel mutation I215V in the PRNP gene associated with Creutzfeldt-Jakob and Alzheimer's diseases in three patients with divergent clinical phenotypes
-
Muñoz-Nieto, M., Ramonet, N., López-Gastón, J. I., Cuadrado-Corrales, N., Calero, O., Díaz-Hurtado, M., et al. (2013). A novel mutation I215V in the PRNP gene associated with Creutzfeldt-Jakob and Alzheimer's diseases in three patients with divergent clinical phenotypes. J. Neurol. 260, 77-84. doi: 10.1007/s00415-012-6588-1
-
(2013)
J. Neurol
, vol.260
, pp. 77-84
-
-
Muñoz-Nieto, M.1
Ramonet, N.2
López-Gastón, J.I.3
Cuadrado-Corrales, N.4
Calero, O.5
Díaz-Hurtado, M.6
-
62
-
-
84919392782
-
Effects of multiple genetic Loci on age at onset in late-onset Alzheimer disease: A genome-wide association study
-
Naj, A. C., Jun, G., Reitz, C., Kunkle, B. W., Perry, W., Park, Y. S., et al. (2014). Effects of multiple genetic Loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 71, 1394-1404. doi: 10.1001/jamaneurol.2014.1491
-
(2014)
JAMA Neurol
, vol.71
, pp. 1394-1404
-
-
Naj, A.C.1
Jun, G.2
Reitz, C.3
Kunkle, B.W.4
Perry, W.5
Park, Y.S.6
-
63
-
-
84907970240
-
Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease
-
Parcerisas, A., Rubio, S. E., Muhaisen, A., Gómez-Ramos, A., Pujadas, L., Puiggros, M., et al. (2014). Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease. J. Alzheimers. Dis. 42, 1357-1382. doi: 10.3233/JAD-140891
-
(2014)
J. Alzheimers. Dis
, vol.42
, pp. 1357-1382
-
-
Parcerisas, A.1
Rubio, S.E.2
Muhaisen, A.3
Gómez-Ramos, A.4
Pujadas, L.5
Puiggros, M.6
-
64
-
-
84897516307
-
Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects
-
Pedraza, O., Allen, M., Jennette, K., Carrasquillo, M., Crook, J., Serie, D., et al. (2014). Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects. Alzheimers Dement 10, 205-213. doi: 10.1016/j.jalz.2013.01.016
-
(2014)
Alzheimers Dement
, vol.10
, pp. 205-213
-
-
Pedraza, O.1
Allen, M.2
Jennette, K.3
Carrasquillo, M.4
Crook, J.5
Serie, D.6
-
65
-
-
54149088214
-
Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips, P. C. (2008). Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet. 9, 855-867. doi: 10.1038/nrg2452
-
(2008)
Nat. Rev. Genet
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
66
-
-
70450223891
-
Common disorders are quantitative traits
-
Plomin, R., Haworth, C. M., and Davis, O. S. (2009). Common disorders are quantitative traits. Nat. Rev. Genet. 10, 872-878. doi: 10.1038/nrg2670
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 872-878
-
-
Plomin, R.1
Haworth, C.M.2
Davis, O.S.3
-
67
-
-
84879756120
-
Somatic mutation, genomic variation, and neurological disease
-
Poduri, A., Evrony, G. D., Cai, X., and Walsh, C. A. (2013). Somatic mutation, genomic variation, and neurological disease. Science 341:1237758. doi: 10.1126/science.1237758
-
(2013)
Science
, vol.341
, pp. 1237758
-
-
Poduri, A.1
Evrony, G.D.2
Cai, X.3
Walsh, C.A.4
-
68
-
-
84980053612
-
Pathways to neurodegeneration: Mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders
-
Ramanan, V. K., and Saykin, A. J. (2013). Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders. Am. J. Neurodegener. Dis. 2, 145-175.
-
(2013)
Am. J. Neurodegener. Dis
, vol.2
, pp. 145-175
-
-
Ramanan, V.K.1
Saykin, A.J.2
-
69
-
-
26944475934
-
Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: An update
-
Raux, G., Guyant-Maréchal, L., Martin, C., Bou, J., Penet, C., Brice, A., et al. (2005). Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: an update. J. Med. Genet. 42, 793-795. doi: 10.1136/jmg.2005.033456
-
(2005)
J. Med. Genet
, vol.42
, pp. 793-795
-
-
Raux, G.1
Guyant-Maréchal, L.2
Martin, C.3
Bou, J.4
Penet, C.5
Brice, A.6
-
70
-
-
84879113935
-
TREM2 in neurodegeneration: Evidence for association of the p. R47H variant with frontotemporal dementia and Parkinson's disease
-
Rayaprolu, S., Mullen, B., Baker, M., Lynch, T., Finger, E., Seeley, W. W., et al. (2013). TREM2 in neurodegeneration: evidence for association of the p. R47H variant with frontotemporal dementia and Parkinson's disease. Mol. Neurodegener. 8, 19. doi: 10.1186/1750-1326-8-19
-
(2013)
Mol. Neurodegener
, vol.8
, pp. 19
-
-
Rayaprolu, S.1
Mullen, B.2
Baker, M.3
Lynch, T.4
Finger, E.5
Seeley, W.W.6
-
71
-
-
20044379205
-
Constitutional aneuploidy in the normal human brain
-
Rehen, S. K., Yung, Y. C., McCreight, M. P., Kaushal, D., Yang, A. H., Almeida, B. S., et al. (2005). Constitutional aneuploidy in the normal human brain. J. Neurosci. 25, 2176-2180. doi: 10.1523/JNEUROSCI.4560-04.2005
-
(2005)
J. Neurosci
, vol.25
, pp. 2176-2180
-
-
Rehen, S.K.1
Yung, Y.C.2
McCreight, M.P.3
Kaushal, D.4
Yang, A.H.5
Almeida, B.S.6
-
72
-
-
84897954407
-
Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers
-
Reitz, C., and Mayeux, R. (2014). Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers. Biochem. Pharmacol. 88, 640-651. doi: 10.1016/j.bcp.2013.12.024
-
(2014)
Biochem. Pharmacol
, vol.88
, pp. 640-651
-
-
Reitz, C.1
Mayeux, R.2
-
73
-
-
84881476107
-
Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease
-
Rhinn, H., Fujita, R., Qiang, L., Cheng, R., Lee, J. H., and Abeliovich, A. (2013). Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease. Nature 500, 45-50. doi: 10.1038/nature12415
-
(2013)
Nature
, vol.500
, pp. 45-50
-
-
Rhinn, H.1
Fujita, R.2
Qiang, L.3
Cheng, R.4
Lee, J.H.5
Abeliovich, A.6
-
74
-
-
84892407135
-
Alzheimer's disease: Analyzing the missing heritability
-
Ridge, P. G., Mukherjee, S., Crane, P. K., Kauwe, J. S., and Alzheimer's Disease Genetics Consortium. (2013). Alzheimer's disease: analyzing the missing heritability. PLoS ONE 8:e79771. doi: 10.1371/journal.pone.0079771
-
(2013)
PLoS ONE
, vol.8
-
-
Ridge, P.G.1
Mukherjee, S.2
Crane, P.K.3
Kauwe, J.S.4
Alzheimer's Disease Genetics Consortium5
-
75
-
-
84920759928
-
Finding the epistasis needles in the genome-wide haystack
-
Ritchie, M. D. (2015). Finding the epistasis needles in the genome-wide haystack. Methods Mol. Biol. 1253, 19-33. doi: 10.1007/978-1-4939-2155-3_2
-
(2015)
Methods Mol. Biol
, vol.1253
, pp. 19-33
-
-
Ritchie, M.D.1
-
76
-
-
1942469548
-
Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease
-
Robson, K. J., Lehmann, D. J., Wimhurst, V. L., Livesey, K. J., Combrinck, M., and Merryweather-Clarke, A. T.et al. (2004). Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease. J. Med. Genet. 41, 261-265. doi: 10.1136/jmg.2003.015552
-
(2004)
J. Med. Genet
, vol.41
, pp. 261-265
-
-
Robson, K.J.1
Lehmann, D.J.2
Wimhurst, V.L.3
Livesey, K.J.4
Combrinck, M.5
Merryweather-Clarke, A.T.6
-
77
-
-
84903818205
-
Exome sequencing identifies 2 novel presenilin 1 mutations (p. L166V and p.S230R) in British early-onset Alzheimer's disease
-
Sassi, C., Guerreiro, R., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., et al. (2014a). Exome sequencing identifies 2 novel presenilin 1 mutations (p. L166V and p.S230R) in British early-onset Alzheimer's disease. Neurobiol. Aging 35, 2422.e13-2422.e16. doi: 10.1016/j.neurobiolaging.2014.04.026
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Sassi, C.1
Guerreiro, R.2
Gibbs, R.3
Ding, J.4
Lupton, M.K.5
Troakes, C.6
-
78
-
-
84911430470
-
Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease
-
Sassi, C., Guerreiro, R., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., et al. (2014b). Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease. Neurobiol. Aging 35, 2881.e1-2881.e6. doi: 10.1016/j.neurobiolaging.2014.06.002
-
(2014)
Neurobiol. Aging
, vol.35
-
-
Sassi, C.1
Guerreiro, R.2
Gibbs, R.3
Ding, J.4
Lupton, M.K.5
Troakes, C.6
-
79
-
-
84899809381
-
Genetic analysis of quantitative phenotypes in AD and MCI: Imaging, cognition and biomarkers
-
Shen, L., Thompson, P. M., Potkin, S. G., Bertram, L., Farrer, L. A., Foroud, T. M., et al. (2014). Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imag. Behav. 8, 183-207. doi: 10.1007/s11682-013-9262-z
-
(2014)
Brain Imag. Behav
, vol.8
, pp. 183-207
-
-
Shen, L.1
Thompson, P.M.2
Potkin, S.G.3
Bertram, L.4
Farrer, L.A.5
Foroud, T.M.6
-
80
-
-
0029120035
-
Apolipoprotein E: An important gene and protein to follow in laboratory medicine
-
Siest, G., Pillot, T., Régis-Bailly, A., Leininger-Muller, B., Steinmetz, J., Galteau, M. M., et al. (1995). Apolipoprotein E: an important gene and protein to follow in laboratory medicine. Clin. Chem. 41(Pt 1), 1068-1086.
-
(1995)
Clin. Chem
, vol.41
, pp. 1068-1086
-
-
Siest, G.1
Pillot, T.2
Régis-Bailly, A.3
Leininger-Muller, B.4
Steinmetz, J.5
Galteau, M.M.6
-
81
-
-
84927137044
-
R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia
-
Slattery, C. F., Beck, J. A., Harper, L., Adamson, G., Abdi, Z., Uphill, J., et al. (2014). R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia. Alzheimers Dement 10, 602-608. doi: 10.1016/j.jalz.2014.05.1751
-
(2014)
Alzheimers Dement
, vol.10
, pp. 602-608
-
-
Slattery, C.F.1
Beck, J.A.2
Harper, L.3
Adamson, G.4
Abdi, Z.5
Uphill, J.6
-
82
-
-
33750579333
-
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy
-
Sleegers, K., Brouwers, N., Gijselinck, I., Theuns, J., Goossens, D., Wauters, J., et al. (2006). APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy. Brain 129(Pt 11), 2977-2983. doi: 10.1093/brain/awl203
-
(2006)
Brain
, vol.129
, pp. 2977-2983
-
-
Sleegers, K.1
Brouwers, N.2
Gijselinck, I.3
Theuns, J.4
Goossens, D.5
Wauters, J.6
-
83
-
-
0029001744
-
Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease
-
Sorbi, S., Nacmias, B., Forleo, P., Piacentini, S., Latorraca, S., and Amaducci, L. (1995). Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease. Ann. Neurol. 38, 124-127. doi: 10.1002/ana.410380120
-
(1995)
Ann. Neurol
, vol.38
, pp. 124-127
-
-
Sorbi, S.1
Nacmias, B.2
Forleo, P.3
Piacentini, S.4
Latorraca, S.5
Amaducci, L.6
-
84
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W. J., Saunders, A. M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G. S., et al. (1993). Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90, 1977-1981. doi: 10.1073/pnas.90.5.1977
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
-
85
-
-
41749096713
-
A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia
-
Tomiyama, T., Nagata, T., Shimada, H., Teraoka, R., Fukushima, A., Kanemitsu, H., et al. (2008). A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia. Ann. Neurol. 63, 377-387. doi: 10.1002/ana.21321
-
(2008)
Ann. Neurol
, vol.63
, pp. 377-387
-
-
Tomiyama, T.1
Nagata, T.2
Shimada, H.3
Teraoka, R.4
Fukushima, A.5
Kanemitsu, H.6
-
86
-
-
84908162497
-
Detecting epistasis in human complex traits
-
Wei, W. H., Hemani, G., and Haley, C. S. (2014). Detecting epistasis in human complex traits. Nat. Rev. Genet. 15, 722-733. doi: 10.1038/nrg3747
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 722-733
-
-
Wei, W.H.1
Hemani, G.2
Haley, C.S.3
-
87
-
-
84879324656
-
Pitfalls of predicting complex traits from SNPs
-
Wray, N. R., Yang, J., Hayes, B. J., Price, A. L., Goddard, M. E., and Visscher, P. M. (2013). Pitfalls of predicting complex traits from SNPs. Nat. Rev. Genet. 14, 507-515. doi: 10.1038/nrg3457
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 507-515
-
-
Wray, N.R.1
Yang, J.2
Hayes, B.J.3
Price, A.L.4
Goddard, M.E.5
Visscher, P.M.6
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