Missense variant in TREML2 protects against Alzheimer's disease

Neurobiology of Aging

Volumn 35, Issue 6, 2014, Pages 1510.e19-1510.e26

  Benitez, Bruno A ^a   Jin, Sheng Chih ^a   Guerreiro, Rita ^d,e   Graham, Rob ^c   Lord, Jenny ⁿ   Harold, Denise ^b   Sims, Rebecca ^b   Lambert, Jean Charles ^p,q,r   Gibbs, J Raphael ^d,e   Bras, Jose ^d   Sassi, Celeste ^d,e   Harari, Oscar ^a   Bertelsen, Sarah ^a   Lupton, Michelle K ^o   Powell, John ^o   Bellenguez, Celine ^p,q,r   Brown, Kristelle ⁿ   Medway, Christopher ⁿ   Haddick, Patrick CG ^c   Van der Brug, Marcel P ^c   Bhangale, Tushar ^c   Ortmann, Ward ^c   Behrens, Tim ^c   Mayeux, Richard ^g,h   Pericak Vance, Margaret A ⁱ   Farrer, Lindsay A ^j,k   Schellenberg, Gerard D ^l   Haines, Jonathan L ^m   Turton, Jim ⁿ   Braae, Anne ⁿ   Barber, Imelda ⁿ   Fagan, Anne M ^a   Holtzman, David M ^a   Morris, John C ^a   Williams, Julie ^b   Kauwe, John S K ^f   Amouyel, Philippe ^p,q,r   Morgan, Kevin ⁿ   Singleton, Andy ^c   Hardy, John ^c   Goate, Alison M ^a   Cruchaga, Carlos ^a,q   more..

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c GENENTECH INC   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f BRIGHAM YOUNG UNIVERSITY   (United States)

^g Och Spine at New York Presbyterian Hospitals   (United States)

^h Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

ⁱ UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^j BOSTON UNIVERSITY   (United States)

^k BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l UNIVERSITY OF PENNSYLVANIA   (United States)

^m VANDERBILT UNIVERSITY   (United States)

ⁿ UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^o KING'S COLLEGE LONDON   (United Kingdom)

^p INSERM   (France)

^q UNIV LILLE   (France)

^r INSTITUT PASTEUR DE LILLE   (France)

more..

Author keywords

Alzheimer's disease; Association; Conditional analysis; Endophenotype; Gene; Genome wide association studies; TREM2

Indexed keywords

TAU PROTEIN; BIOLOGICAL MARKER; IMMUNOGLOBULIN RECEPTOR; TREML2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; EXOME; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MICROGLIA; MISSENSE MUTATION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TREML2 GENE; CEREBROSPINAL FLUID; CHROMOSOME 6; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; META ANALYSIS (TOPIC); PHYSIOLOGY; RISK;

ALZHEIMER DISEASE; BIOMARKERS; CHROMOSOMES, HUMAN, PAIR 6; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; META-ANALYSIS AS TOPIC; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, IMMUNOLOGIC; RISK;

EID: 84903366979     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.12.010     Document Type: Article

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