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Volumn 137, Issue 11, 2014, Pages 2938-2950

Serum microRNAs in patients with genetic amyotrophic lateral sclerosis and pre-manifest mutation carriers

Author keywords

Amyotrophic lateral sclerosis; C9ORF72; MicroRNA; Mutation carriers; SOD1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MICRORNA; MICRORNA 1281; MICRORNA 149; MICRORNA 1825; MICRORNA 1915; MICRORNA 2861; MICRORNA 3185; MICRORNA 3196; MICRORNA 3613; MICRORNA 4270; MICRORNA 4466; MICRORNA 4508; MICRORNA 4516; MICRORNA 4530; MICRORNA 4532; MICRORNA 455; MICRORNA 4707; MICRORNA 4725; MICRORNA 4734; MICRORNA 4745; MICRORNA 638; UNCLASSIFIED DRUG; C9ORF72 PROTEIN, HUMAN; PROTEIN; SUPEROXIDE DISMUTASE;

EID: 84927566123     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu249     Document Type: Article
Times cited : (86)

References (80)
  • 2
    • 0030272143 scopus 로고    scopus 로고
    • Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS
    • Aman P, Panagopoulos I, Lassen C, Fioretos T, Mencinger M, Toresson H, et al. Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS. Genomics 1996; 37: 1-8.
    • (1996) Genomics , vol.37 , pp. 1-8
    • Aman, P.1    Panagopoulos, I.2    Lassen, C.3    Fioretos, T.4    Mencinger, M.5    Toresson, H.6
  • 3
    • 79958090979 scopus 로고    scopus 로고
    • DREME: Motif discovery in transcription factor ChIP-seq data
    • Bailey TL. DREME: motif discovery in transcription factor ChIP-seq data. Bioinformatics 2011; 27: 1653-9.
    • (2011) Bioinformatics , vol.27 , pp. 1653-1659
    • Bailey, T.L.1
  • 5
    • 84876581756 scopus 로고    scopus 로고
    • Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing
    • Burgos KL, Javaherian A, Bomprezzi R, Ghaffari L, Rhodes S, Courtright A, et al. Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing. RNA 2013; 19: 712-22.
    • (2013) RNA , vol.19 , pp. 712-722
    • Burgos, K.L.1    Javaherian, A.2    Bomprezzi, R.3    Ghaffari, L.4    Rhodes, S.5    Courtright, A.6
  • 6
    • 84865987121 scopus 로고    scopus 로고
    • Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
    • Butovsky O, Siddiqui S, Gabriely G, Lanser AJ, Dake B, Murugaiyan G, et al. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J Clin Invest 2012; 122: 3063-87.
    • (2012) J Clin Invest , vol.122 , pp. 3063-3087
    • Butovsky, O.1    Siddiqui, S.2    Gabriely, G.3    Lanser, A.J.4    Dake, B.5    Murugaiyan, G.6
  • 7
    • 84878005741 scopus 로고    scopus 로고
    • Altered microRNA expression profile in amyotrophic lateral sclerosis: A role in the regulation of NFL mRNA levels
    • Campos-Melo D, Droppelmann CA, He Z, Volkening K, Strong MJ. Altered microRNA expression profile in Amyotrophic Lateral Sclerosis: a role in the regulation of NFL mRNA levels. Mol Brain 2013; 6: 26.
    • (2013) Mol Brain , vol.6 , pp. 26
    • Campos-Melo, D.1    Droppelmann, C.A.2    He, Z.3    Volkening, K.4    Strong, M.J.5
  • 8
    • 77953503937 scopus 로고    scopus 로고
    • Riluzole, neuroprotection and amyotrophic lateral sclerosis
    • Cheah BC, Vucic S, Krishnan AV, Kiernan MC. Riluzole, neuroprotection and amyotrophic lateral sclerosis. Curr Med Chem 2010; 17: 1942-199.
    • (2010) Curr Med Chem , vol.17 , pp. 1942-1999
    • Cheah, B.C.1    Vucic, S.2    Krishnan, A.V.3    Kiernan, M.C.4
  • 9
    • 2442658908 scopus 로고    scopus 로고
    • DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
    • Chen YZ, Bennett CL, Huynh HM, Blair IP, Puls I, Irobi J, et al. DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Am J Hum Genet 2004; 74: 1128-35.
    • (2004) Am J Hum Genet , vol.74 , pp. 1128-1135
    • Chen, Y.Z.1    Bennett, C.L.2    Huynh, H.M.3    Blair, I.P.4    Puls, I.5    Irobi, J.6
  • 10
    • 84878757129 scopus 로고    scopus 로고
    • Plasma processing conditions substantially influence circulating microRNA bio-marker levels
    • Cheng HH, Yi HS, Kim Y, Kroh EM, Chien JW, Eaton KD, et al. Plasma processing conditions substantially influence circulating microRNA bio-marker levels. PLoS One 2013; 8: e64795.
    • (2013) PLoS One , vol.8
    • Cheng, H.H.1    Yi, H.S.2    Kim, Y.3    Kroh, E.M.4    Chien, J.W.5    Eaton, K.D.6
  • 13
    • 33751003820 scopus 로고    scopus 로고
    • Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis
    • Crosio C, Casciati A, Iaccarino C, Rotilio G, Carri MT. Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis. Cell Death Differ 2006; 13: 2150-3.
    • (2006) Cell Death Differ , vol.13 , pp. 2150-2153
    • Crosio, C.1    Casciati, A.2    Iaccarino, C.3    Rotilio, G.4    Carri, M.T.5
  • 14
    • 76649122794 scopus 로고    scopus 로고
    • Sensitivity of electrophysiological tests for upper and lower motor neuron dysfunction in ALS: A six-month longitudinal study
    • de Carvalho M, Swash M. Sensitivity of electrophysiological tests for upper and lower motor neuron dysfunction in ALS: a six-month longitudinal study. Muscle Nerve 2010; 41: 208-11.
    • (2010) Muscle Nerve , vol.41 , pp. 208-211
    • De Carvalho, M.1    Swash, M.2
  • 15
    • 84865536102 scopus 로고    scopus 로고
    • A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis
    • De Felice B, Guida M, Coppola C, De Mieri G, Cotrufo R. A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene 2012; 508: 35-40.
    • (2012) Gene , vol.508 , pp. 35-40
    • De Felice, B.1    Guida, M.2    Coppola, C.3    De Mieri, G.4    Cotrufo, R.5
  • 16
    • 80054832080 scopus 로고    scopus 로고
    • Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
    • DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011; 72: 245-56.
    • (2011) Neuron , vol.72 , pp. 245-256
    • DeJesus-Hernandez, M.1    Mackenzie, I.R.2    Boeve, B.F.3    Boxer, A.L.4    Baker, M.5    Rutherford, N.J.6
  • 17
    • 3343020674 scopus 로고    scopus 로고
    • Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: Benefit of a high-energy diet in a transgenic mouse model
    • Dupuis L, Oudart H, Rene F, Gonzalez de Aguilar JL, Loeffler JP. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proc Natl Acad Sci USA 2004; 101: 11159-64.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11159-11164
    • Dupuis, L.1    Oudart, H.2    Rene, F.3    Gonzalez De Aguilar, J.L.4    Loeffler, J.P.5
  • 18
    • 77956155218 scopus 로고    scopus 로고
    • Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
    • Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, et al. Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature 2010; 466: 1069-75.
    • (2010) Nature , vol.466 , pp. 1069-1075
    • Elden, A.C.1    Kim, H.J.2    Hart, M.P.3    Chen-Plotkin, A.S.4    Johnson, B.S.5    Fang, X.6
  • 22
    • 0345184327 scopus 로고    scopus 로고
    • Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord
    • Hu JH, Zhang H, Wagey R, Krieger C, Pelech SL. Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord. J Neurochem 2003; 85: 432-42.
    • (2003) J Neurochem , vol.85 , pp. 432-442
    • Hu, J.H.1    Zhang, H.2    Wagey, R.3    Krieger, C.4    Pelech, S.L.5
  • 23
    • 79953327693 scopus 로고    scopus 로고
    • A runx2/MIR-3960/MIR-2861 regulatory feedback loop during mouse osteoblast differentiation
    • Hu R, Liu W, Li H, Yang L, Chen C, Xia ZY, et al. A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation. J Biol Chem 2011; 286: 12328-39.
    • (2011) J Biol Chem , vol.286 , pp. 12328-12339
    • Hu, R.1    Liu, W.2    Li, H.3    Yang, L.4    Chen, C.5    Xia, Z.Y.6
  • 24
    • 84893718348 scopus 로고    scopus 로고
    • Polymerase chain reaction and Southern blot-based analysis of the C9orf72 hexanucleotide repeat in different motor neuron diseases
    • Hubers A, Marroquin N, Schmoll B, Vielhaber S, Just M, Mayer B, et al. Polymerase chain reaction and Southern blot-based analysis of the C9orf72 hexanucleotide repeat in different motor neuron diseases. Neurobiol Aging 2014; 35: 1214.
    • (2014) Neurobiol Aging , vol.35 , pp. 1214
    • Hubers, A.1    Marroquin, N.2    Schmoll, B.3    Vielhaber, S.4    Just, M.5    Mayer, B.6
  • 25
    • 84875251623 scopus 로고    scopus 로고
    • A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts
    • Ingre C, Landers JE, Rizik N, Volk AE, Akimoto C, Birve A, et al. A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, Nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts. Neurobiol Aging 2013; 34: 1708.
    • (2013) Neurobiol Aging , vol.34 , pp. 1708
    • Ingre, C.1    Landers, J.E.2    Rizik, N.3    Volk, A.E.4    Akimoto, C.5    Birve, A.6
  • 28
    • 0028881190 scopus 로고
    • Cell type-specific expression of hnRNP proteins
    • Kamma H, Portman DS, Dreyfuss G. Cell type-specific expression of hnRNP proteins. Exp Cell Res 1995; 221: 187-96.
    • (1995) Exp Cell Res , vol.221 , pp. 187-196
    • Kamma, H.1    Portman, D.S.2    Dreyfuss, G.3
  • 29
    • 84857772495 scopus 로고    scopus 로고
    • TDP-43 promotes microRNA biogenesis as a component of the drosha and dicer complexes
    • Kawahara Y, Mieda-Sato A. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc Natl Acad Sci USA 2012; 109: 3347-52.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3347-3352
    • Kawahara, Y.1    Mieda-Sato, A.2
  • 30
    • 84875605133 scopus 로고    scopus 로고
    • Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
    • Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature 2013; 495: 467-73.
    • (2013) Nature , vol.495 , pp. 467-473
    • Kim, H.J.1    Kim, N.C.2    Wang, Y.D.3    Scarborough, E.A.4    Moore, J.5    Diaz, Z.6
  • 33
    • 67650094927 scopus 로고    scopus 로고
    • Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age
    • Kok E, Haikonen S, Luoto T, Huhtala H, Goebeler S, Haapasalo H, et al. Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol 2009; 65: 650-7.
    • (2009) Ann Neurol , vol.65 , pp. 650-657
    • Kok, E.1    Haikonen, S.2    Luoto, T.3    Huhtala, H.4    Goebeler, S.5    Haapasalo, H.6
  • 34
    • 0029881099 scopus 로고    scopus 로고
    • Skin involvement in amyotrophic lateral sclerosis
    • Kolde G, Bachus R, Ludolph AC. Skin involvement in amyotrophic lateral sclerosis. Lancet 1996; 347: 1226-7.
    • (1996) Lancet , vol.347 , pp. 1226-1227
    • Kolde, G.1    Bachus, R.2    Ludolph, A.C.3
  • 35
    • 3042552023 scopus 로고    scopus 로고
    • Controlling the number of false discoveries: Application to high-dimensional genomic data
    • Korn EL, Troendleb JF, McShanea LM, Simon R. Controlling the number of false discoveries: application to high-dimensional genomic data. J Stat Plan Inference 2004; 124: 379-98.
    • (2004) J Stat Plan Inference , vol.124 , pp. 379-398
    • Korn, E.L.1    Troendleb, J.F.2    McShanea, L.M.3    Simon, R.4
  • 37
    • 84884712642 scopus 로고    scopus 로고
    • Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
    • Koval ED, Shaner C, Zhang P, du Maine X, Fischer K, Tay J, et al. Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice. Hum Mol Genet 2013; 22: 4127-35.
    • (2013) Hum Mol Genet , vol.22 , pp. 4127-4135
    • Koval, E.D.1    Shaner, C.2    Zhang, P.3    Du Maine, X.4    Fischer, K.5    Tay, J.6
  • 38
    • 84885960715 scopus 로고    scopus 로고
    • Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells
    • Kuehner S, Holzmann K, Speit G. Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells. Arch Toxicol 2013; 87: 1999-2012.
    • (2013) Arch Toxicol , vol.87 , pp. 1999-2012
    • Kuehner, S.1    Holzmann, K.2    Speit, G.3
  • 39
    • 61349156118 scopus 로고    scopus 로고
    • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
    • Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009; 323: 1205-8.
    • (2009) Science , vol.323 , pp. 1205-1208
    • Kwiatkowski, T.J.1    Bosco, D.A.2    Leclerc, A.L.3    Tamrazian, E.4    Vanderburg, C.R.5    Russ, C.6
  • 43
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25: 402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 44
    • 84879476159 scopus 로고    scopus 로고
    • Integrated miRNA-mRNA analysis revealing the potential roles of miRNAs in chordomas
    • Long C, Jiang L, Wei F, Ma C, Zhou H, Yang S, et al. Integrated miRNA-mRNA analysis revealing the potential roles of miRNAs in chordomas. PLoS One 2013; 8: e66676.
    • (2013) PLoS One , vol.8
    • Long, C.1    Jiang, L.2    Wei, F.3    Ma, C.4    Zhou, H.5    Yang, S.6
  • 45
    • 84901608994 scopus 로고    scopus 로고
    • Loss of MIR-638 in vitro promotes cell invasion and a mesenchymal-like transition by influencing SOX2 expression in colorectal carcinoma cells
    • Ma K, Pan X, Fan P, He Y, Gu J, Wang W, et al. Loss of miR-638 in vitro promotes cell invasion and a mesenchymal-like transition by influencing SOX2 expression in colorectal carcinoma cells. Mol Cancer 2014; 13: 118.
    • (2014) Mol Cancer , vol.13 , pp. 118
    • Ma, K.1    Pan, X.2    Fan, P.3    He, Y.4    Gu, J.5    Wang, W.6
  • 46
    • 34249946466 scopus 로고    scopus 로고
    • Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
    • Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol 2007; 61: 427-34.
    • (2007) Ann Neurol , vol.61 , pp. 427-434
    • Mackenzie, I.R.1    Bigio, E.H.2    Ince, P.G.3    Geser, F.4    Neumann, M.5    Cairns, N.J.6
  • 47
    • 84858622829 scopus 로고    scopus 로고
    • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: A cross-sectional study
    • Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol 2012; 11: 323-30.
    • (2012) Lancet Neurol , vol.11 , pp. 323-330
    • Majounie, E.1    Renton, A.E.2    Mok, K.3    Dopper, E.G.4    Waite, A.5    Rollinson, S.6
  • 48
    • 0014691242 scopus 로고
    • Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
    • McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244: 6049-55.
    • (1969) J Biol Chem , vol.244 , pp. 6049-6055
    • McCord, J.M.1    Fridovich, I.2
  • 49
    • 84858379476 scopus 로고    scopus 로고
    • MicroRNAs in stress signaling and human disease
    • Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell 2012; 148: 1172-87.
    • (2012) Cell , vol.148 , pp. 1172-1187
    • Mendell, J.T.1    Olson, E.N.2
  • 50
    • 34250208597 scopus 로고    scopus 로고
    • Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
    • Miller RG, Mitchell JD, Moore DH. Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). Cochrane Database Syst Rev 2012: CD001447.
    • Cochrane Database Syst Rev , vol.2012
    • Miller, R.G.1    Mitchell, J.D.2    Moore, D.H.3
  • 52
    • 84871002507 scopus 로고    scopus 로고
    • FUS stimulates microRNA biogenesis by facilitating co-transcriptional drosha recruitment
    • Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J 2012; 31: 4502-10.
    • (2012) EMBO J , vol.31 , pp. 4502-4510
    • Morlando, M.1    Dini Modigliani, S.2    Torrelli, G.3    Rosa, A.4    Di Carlo, V.5    Caffarelli, E.6
  • 53
    • 84891768855 scopus 로고    scopus 로고
    • Expression atlas update - A database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments
    • Petryszak R, Burdett T, Fiorelli B, Fonseca NA, Gonzalez-Porta M, Hastings E, et al. Expression Atlas update - a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments. Nucleic Acids Res 2014; 42: D926-32.
    • (2014) Nucleic Acids Res , vol.42 , pp. D926-D932
    • Petryszak, R.1    Burdett, T.2    Fiorelli, B.3    Fonseca, N.A.4    Gonzalez-Porta, M.5    Hastings, E.6
  • 54
  • 55
    • 84893649256 scopus 로고    scopus 로고
    • State of play in amyotrophic lateral sclerosis genetics
    • Renton AE, Chio A, Traynor BJ. State of play in amyotrophic lateral sclerosis genetics. Nat Neurosci 2014; 17: 17-23.
    • (2014) Nat Neurosci , vol.17 , pp. 17-23
    • Renton, A.E.1    Chio, A.2    Traynor, B.J.3
  • 56
    • 80054837386 scopus 로고    scopus 로고
    • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
    • Renton AE, Majounie E, Waite A, Simon-Sanchez J, Rollinson S, Gibbs JR, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011; 72: 257-68.
    • (2011) Neuron , vol.72 , pp. 257-268
    • Renton, A.E.1    Majounie, E.2    Waite, A.3    Simon-Sanchez, J.4    Rollinson, S.5    Gibbs, J.R.6
  • 58
    • 0021364776 scopus 로고
    • Increased fragility of erythrocytes from amyotrophic lateral sclerosis (ALS) patients provoked by mechanical stress
    • Ronnevi LO, Conradi S. Increased fragility of erythrocytes from amyotrophic lateral sclerosis (ALS) patients provoked by mechanical stress. Acta Neurol Scand 1984; 69: 20-6.
    • (1984) Acta Neurol Scand , vol.69 , pp. 20-26
    • Ronnevi, L.O.1    Conradi, S.2
  • 59
    • 0742323507 scopus 로고    scopus 로고
    • Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis
    • Sach M, Winkler G, Glauche V, Liepert J, Heimbach B, Koch MA, et al. Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis. Brain 2004; 127: 340-50.
    • (2004) Brain , vol.127 , pp. 340-350
    • Sach, M.1    Winkler, G.2    Glauche, V.3    Liepert, J.4    Heimbach, B.5    Koch, M.A.6
  • 61
    • 65749093295 scopus 로고    scopus 로고
    • Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex
    • Sethi P, Lukiw WJ. Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer's disease temporal lobe neocortex. Neurosci Lett 2009; 459: 100-4.
    • (2009) Neurosci Lett , vol.459 , pp. 100-104
    • Sethi, P.1    Lukiw, W.J.2
  • 62
    • 41149180753 scopus 로고    scopus 로고
    • TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
    • Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 2008; 319: 1668-72.
    • (2008) Science , vol.319 , pp. 1668-1672
    • Sreedharan, J.1    Blair, I.P.2    Tripathi, V.B.3    Hu, X.4    Vance, C.5    Rogelj, B.6
  • 63
    • 84872812457 scopus 로고    scopus 로고
    • Expression of MIR-150 and MIR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features
    • Sun Y, Su B, Zhang P, Xie H, Zheng H, Xu Y, et al. Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features. Oncol Rep 2013; 29: 704-12.
    • (2013) Oncol Rep , vol.29 , pp. 704-712
    • Sun, Y.1    Su, B.2    Zhang, P.3    Xie, H.4    Zheng, H.5    Xu, Y.6
  • 64
    • 84865536932 scopus 로고    scopus 로고
    • Hepatic activation of IKK/NFkappaB signaling induces liver fibrosis via macrophage-mediated chronic inflammation
    • Sunami Y, Leithauser F, Gul S, Fiedler K, Guldiken N, Espenlaub S, et al. Hepatic activation of IKK/NFkappaB signaling induces liver fibrosis via macrophage-mediated chronic inflammation. Hepatology 2012; 56: 1117-28.
    • (2012) Hepatology , vol.56 , pp. 1117-1128
    • Sunami, Y.1    Leithauser, F.2    Gul, S.3    Fiedler, K.4    Guldiken, N.5    Espenlaub, S.6
  • 66
    • 84867915488 scopus 로고    scopus 로고
    • Extracellular miRNAs: The mystery of their origin and function
    • Turchinovich A, Weiz L, Burwinkel B. Extracellular miRNAs: the mystery of their origin and function. Trends Biochem Sci 2012; 37: 460-5.
    • (2012) Trends Biochem Sci , vol.37 , pp. 460-465
    • Turchinovich, A.1    Weiz, L.2    Burwinkel, B.3
  • 70
    • 82555200943 scopus 로고    scopus 로고
    • MicroRNAs modulate schwann cell response to nerve injury by reinforcing tran-scriptional silencing of dedifferentiation-related genes
    • Viader A, Chang LW, Fahrner T, Nagarajan R, Milbrandt J. MicroRNAs modulate Schwann cell response to nerve injury by reinforcing tran-scriptional silencing of dedifferentiation-related genes. J Neurosci 2011; 31: 17358-69.
    • (2011) J Neurosci , vol.31 , pp. 17358-17369
    • Viader, A.1    Chang, L.W.2    Fahrner, T.3    Nagarajan, R.4    Milbrandt, J.5
  • 72
    • 84873988724 scopus 로고    scopus 로고
    • Truncating mutations in FUS/TLS give rise to a more aggressive ALS-phenotype than missense mutations: A clinico-genetic study in Germany
    • Waibel S, Neumann M, Rosenbohm A, Birve A, Volk AE, Weishaupt JH, et al. Truncating mutations in FUS/TLS give rise to a more aggressive ALS-phenotype than missense mutations: a clinico-genetic study in Germany. Eur J Neurol 2013; 20: 540-6.
    • (2013) Eur J Neurol , vol.20 , pp. 540-546
    • Waibel, S.1    Neumann, M.2    Rosenbohm, A.3    Birve, A.4    Volk, A.E.5    Weishaupt, J.H.6
  • 73
    • 84876287870 scopus 로고    scopus 로고
    • Upregulation of MIR-2861 and MIR-451 expression in papillary thyroid carcinoma with lymph node metastasis
    • Wang Z, Zhang H, Zhang P, Li J, Shan Z, Teng W. Upregulation of miR-2861 and miR-451 expression in papillary thyroid carcinoma with lymph node metastasis. Med Oncol 2013; 30: 577.
    • (2013) Med Oncol , vol.30 , pp. 577
    • Wang, Z.1    Zhang, H.2    Zhang, P.3    Li, J.4    Shan, Z.5    Teng, W.6
  • 74
    • 72149131804 scopus 로고    scopus 로고
    • MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
    • Williams AH, Valdez G, Moresi V, Qi X, McAnally J, Elliott JL, et al. MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 2009; 326: 1549-54.
    • (2009) Science , vol.326 , pp. 1549-1554
    • Williams, A.H.1    Valdez, G.2    Moresi, V.3    Qi, X.4    McAnally, J.5    Elliott, J.L.6
  • 75
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • Wright GW, Simon RM. A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 2003; 19: 2448-55.
    • (2003) Bioinformatics , vol.19 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 76
    • 84865235172 scopus 로고    scopus 로고
    • Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
    • Wu CH, Fallini C, Ticozzi N, Keagle PJ, Sapp PC, Piotrowska K, et al. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature 2012; 488: 499-503.
    • (2012) Nature , vol.488 , pp. 499-503
    • Wu, C.H.1    Fallini, C.2    Ticozzi, N.3    Keagle, P.J.4    Sapp, P.C.5    Piotrowska, K.6
  • 77
    • 84865128457 scopus 로고    scopus 로고
    • Circulating microRNAs: Novel biomarkers for cardiovascular diseases
    • Xu J, Zhao J, Evan G, Xiao C, Cheng Y, Xiao J. Circulating microRNAs: novel biomarkers for cardiovascular diseases. J Mol Med (Berl) 2012; 90: 865-75.
    • (2012) J Mol Med (Berl) , vol.90 , pp. 865-875
    • Xu, J.1    Zhao, J.2    Evan, G.3    Xiao, C.4    Cheng, Y.5    Xiao, J.6
  • 78
    • 84871276136 scopus 로고    scopus 로고
    • MIR-1915 inhibits bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells
    • Xu K, Liang X, Cui D, Wu Y, Shi W, Liu J. miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells. Mol Carcinog 2013; 52: 70-8.
    • (2013) Mol Carcinog , vol.52 , pp. 70-78
    • Xu, K.1    Liang, X.2    Cui, D.3    Wu, Y.4    Shi, W.5    Liu, J.6
  • 79
    • 84868153116 scopus 로고    scopus 로고
    • FUS-SMN protein interactions link the motor neuron diseases ALS and SMA
    • Yamazaki T, Chen S, Yu Y, Yan B, Haertlein TC, Carrasco MA, et al. FUS-SMN protein interactions link the motor neuron diseases ALS and SMA. Cell Rep 2012; 2: 799-806.
    • (2012) Cell Rep , vol.2 , pp. 799-806
    • Yamazaki, T.1    Chen, S.2    Yu, Y.3    Yan, B.4    Haertlein, T.C.5    Carrasco, M.A.6
  • 80
    • 84885444052 scopus 로고    scopus 로고
    • Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations
    • Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, et al. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. PLoS One 2013; 8: e76055.
    • (2013) PLoS One , vol.8
    • Zhang, Z.1    Almeida, S.2    Lu, Y.3    Nishimura, A.L.4    Peng, L.5    Sun, D.6


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