-
2
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs G, Paterson JK, Ludwig JA, Booth GC, Gottesman MM. Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006; 5: 219-234.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth, G.C.4
Gottesman, M.M.5
-
3
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP dependent transporters
-
Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: Role of ATP dependent transporters. Nat Rev Cancer 2002; 2: 48-58.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
4
-
-
0026570652
-
The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo
-
Roninson IB. The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo. Biochem Pharmacol 1992; 43: 95-102.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 95-102
-
-
Roninson, I.B.1
-
5
-
-
0031939392
-
Glutathione-related mechanisms in cellular resistance to anticancer drugs
-
Zhang K, Mack P, Wong KP. Glutathione-related mechanisms in cellular resistance to anticancer drugs. Int J Oncol 1998; 12: 871-882.
-
(1998)
Int J Oncol
, vol.12
, pp. 871-882
-
-
Zhang, K.1
Mack, P.2
Wong, K.P.3
-
6
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: A link between cancer genetics and chemotherapy. Cell 2002; 108: 153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
7
-
-
84984765629
-
Strategies to determine the biological function of microRNAs
-
Krutzfeldt J, Poy MN, Stoffel M. Strategies to determine the biological function of microRNAs. Nat Genet 2006; 38: S14-S19.
-
(2006)
Nat Genet
, vol.38
-
-
Krutzfeldt, J.1
Poy, M.N.2
Stoffel, M.3
-
8
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
9
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP. Vertebrate microRNA genes. Science 2003; 299: 1540.
-
(2003)
Science
, vol.299
, pp. 1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
10
-
-
11844262661
-
Phylogenetic shadowing and computational identification of human microRNA genes
-
Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E. Phylogenetic shadowing and computational identification of human microRNA genes. Cell 2005; 120: 21-24.
-
(2005)
Cell
, vol.120
, pp. 21-24
-
-
Berezikov, E.1
Guryev, V.2
van de Belt, J.3
Wienholds, E.4
Plasterk, R.H.5
Cuppen, E.6
-
11
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
12
-
-
15244358503
-
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
-
Xie X, Lu J, Kulbokas EJ, et al. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 2005; 434: 338-345.
-
(2005)
Nature
, vol.434
, pp. 338-345
-
-
Xie, X.1
Lu, J.2
Kulbokas, E.J.3
-
13
-
-
27244433702
-
Real-time expression profiling of microRNA precursors in human cancer cell lines
-
Jiang J, Lee EJ, Gusev Y, Schmittgen TD. Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res 2005; 33: 5394-5403.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5394-5403
-
-
Jiang, J.1
Lee, E.J.2
Gusev, Y.3
Schmittgen, T.D.4
-
14
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004; 64: 3753-3756.
-
(2004)
Cancer Res
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
Tomida, S.4
Osada, H.5
Endoh, H.6
-
15
-
-
49149114863
-
Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression inhuman cancer cells
-
Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG. Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression inhuman cancer cells. Biochem Pharmacol 2008; 76: 582-588.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 582-588
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Evans, B.R.4
Medina, D.J.5
Liu, C.G.6
-
16
-
-
51049104524
-
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
-
Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther 2008; 7: 2152-2159.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2152-2159
-
-
Kovalchuk, O.1
Filkowski, J.2
Meservy, J.3
Ilnytskyy, Y.4
Tryndyak, V.P.5
Chekhun, V.F.6
-
17
-
-
74149092809
-
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1
-
Zhong XL, Hui W, James X, et al. Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1. Biochem Pharmacol 2010; 79: 817-824.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 817-824
-
-
Zhong, X.L.1
Hui, W.2
James, X.3
-
18
-
-
33646178285
-
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)
-
Castoldi M, Schmidt S, Benes V, et al. A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA 2006; 12: 913-920.
-
(2006)
RNA
, vol.12
, pp. 913-920
-
-
Castoldi, M.1
Schmidt, S.2
Benes, V.3
-
19
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen C, Ridzon DA, Broomer AJ, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 2005; 33: e179.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Chen, C.1
Ridzon, D.A.2
Broomer, A.J.3
-
20
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003; 115: 787-798.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
21
-
-
22244467087
-
MicroRNA-21 is an anti-apoptotic factor in human glioblastoma cells
-
Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an anti-apoptotic factor in human glioblastoma cells. Cancer Res 2005; 65: 6029-6033.
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
22
-
-
18144365478
-
MicroRNA biogenesis and cancer
-
Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Res 2005; 65: 3509-3512.
-
(2005)
Cancer Res
, vol.65
, pp. 3509-3512
-
-
Gregory, R.I.1
Shiekhattar, R.2
-
23
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005; 102: 13944-13949.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
-
24
-
-
49149114863
-
Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
-
Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG. Role of microRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 2008; 76: 582-588.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 582-588
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Evans, B.R.4
Medina, D.J.5
Liu, C.G.6
-
25
-
-
66849113786
-
microRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
-
Pan YZ, Morris ME, Yu AM. microRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. Mol Pharmacol 2009; 75: 1374-1379.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1374-1379
-
-
Pan, Y.Z.1
Morris, M.E.2
Yu, A.M.3
-
26
-
-
34247495591
-
miR-21-mediated tumor growth
-
Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY. miR-21-mediated tumor growth. Oncogene 2007; 26: 2799-2803.
-
(2007)
Oncogene
, vol.26
, pp. 2799-2803
-
-
Si, M.L.1
Zhu, S.2
Wu, H.3
Lu, Z.4
Wu, F.5
Mo, Y.Y.6
-
27
-
-
44949249814
-
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
-
Xia L, Zhang D, Du R, Pan Y, Zhao L, Sun S. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 2008; 123: 372-379.
-
(2008)
Int J Cancer
, vol.123
, pp. 372-379
-
-
Xia, L.1
Zhang, D.2
Du, R.3
Pan, Y.4
Zhao, L.5
Sun, S.6
-
28
-
-
33749507943
-
A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes
-
Kent OA, Mendell JT. A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene 2006; 25: 6188-6196.
-
(2006)
Oncogene
, vol.25
, pp. 6188-6196
-
-
Kent, O.A.1
Mendell, J.T.2
-
29
-
-
40249092910
-
microRNA-21 targets tumor suppressor genes in invasion and metastasis
-
Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. microRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008; 18: 350-359.
-
(2008)
Cell Res
, vol.18
, pp. 350-359
-
-
Zhu, S.1
Wu, H.2
Wu, F.3
Nie, D.4
Sheng, S.5
Mo, Y.Y.6
-
30
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie SF, Alarcon C, Oskarsson T, Padua D, Wang Q, Bos PD. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451: 147-152.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
-
31
-
-
38849107424
-
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
-
Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 2008; 10: 202-210.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 202-210
-
-
Huang, Q.1
Gumireddy, K.2
Schrier, M.3
le Sage, C.4
Nagel, R.5
Nair, S.6
-
32
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
Ma L, Teruya FJ, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449: 682-688.
-
(2007)
Nature
, vol.449
, pp. 682-688
-
-
Ma, L.1
Teruya, F.J.2
Weinberg, R.A.3
-
33
-
-
20544437817
-
Unknotting the roles of Bcl-2 and Bcl-xL in cell death
-
Kim R. Unknotting the roles of Bcl-2 and Bcl-xL in cell death. Biochem Biophys Res Commun 2005; 333: 336-343.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 336-343
-
-
Kim, R.1
-
34
-
-
0031842787
-
Bcl-2 family proteins and leukemia
-
Kusenda J. Bcl-2 family proteins and leukemia. Minirev Neoplasma 1998; 45: 117-122.
-
(1998)
Minirev Neoplasma
, vol.45
, pp. 117-122
-
-
Kusenda, J.1
-
35
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000; 256: 42-49.
-
(2000)
Exp Cell Res
, vol.256
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
36
-
-
0030808385
-
Thymineless death in colon carcinoma cells is mediated via Fas signaling
-
Houghton JA, Harwood FG, Tillman DM. Thymineless death in colon carcinoma cells is mediated via Fas signaling. Proc Natl Acad Sci USA 1997; 94: 8144-8149.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8144-8149
-
-
Houghton, J.A.1
Harwood, F.G.2
Tillman, D.M.3
-
37
-
-
0033044686
-
A Fas dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells
-
Tillman DM, Petak I, Houghton JA. A Fas dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells. Clin Cancer Res 1999; 5: 425-430.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 425-430
-
-
Tillman, D.M.1
Petak, I.2
Houghton, J.A.3
-
38
-
-
34848826227
-
Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA
-
Liang Z, Wu H, Reddy S, Zhu A, Wang S, Blevins D. Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA. Biochem Biophys Res Commun 2007; 363: 542-546.
-
(2007)
Biochem Biophys Res Commun
, vol.363
, pp. 542-546
-
-
Liang, Z.1
Wu, H.2
Reddy, S.3
Zhu, A.4
Wang, S.5
Blevins, D.6
-
39
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins RA, Hemann MT, Zilfou JT, Simpson DR, Ibarra I, Hannon GJ. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet 2005; 37: 1289-1295.
-
(2005)
Nat Genet
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
Simpson, D.R.4
Ibarra, I.5
Hannon, G.J.6
-
40
-
-
33644638088
-
Synthetic microRNA and double-stranded RNA targeting the 30-untranslated region of HER-2/neu mRNA inhibit HER-2 protein expression in ovarian cancer cells
-
Tsuda N, Kawano K, Efferson CL, Ioannides CG. Synthetic microRNA and double-stranded RNA targeting the 30-untranslated region of HER-2/neu mRNA inhibit HER-2 protein expression in ovarian cancer cells. Int J Oncol 2005; 27: 1299-1306.
-
(2005)
Int J Oncol
, vol.27
, pp. 1299-1306
-
-
Tsuda, N.1
Kawano, K.2
Efferson, C.L.3
Ioannides, C.G.4
|