-
1
-
-
5444271023
-
Thyroid development and its disorders: Genetics and molecular mechanisms
-
De Felice, M. & Di Lauro, R. Thyroid development and its disorders: genetics and molecular mechanisms. Endocr. Rev. 25, 722-746 (2004)
-
(2004)
Endocr. Rev
, vol.25
, pp. 722-746
-
-
De Felice, M.1
Di Lauro, R.2
-
2
-
-
24644499978
-
Thyroid development and effect on the nervous system
-
Santisteban, P. & Bernal, J. Thyroid development and effect on the nervous system. Rev. Endocr. Metab. Disord. 6, 217-228 (2005)
-
(2005)
Rev. Endocr. Metab. Disord
, vol.6
, pp. 217-228
-
-
Santisteban, P.1
Bernal, J.2
-
3
-
-
77952888303
-
Morphogenesis of the thyroid gland
-
Fagman, H. & Nilsson, M. Morphogenesis of the thyroid gland. Mol. Cell. Endocrinol. 323, 35-54 (2010)
-
(2010)
Mol. Cell. Endocrinol
, vol.323
, pp. 35-54
-
-
Fagman, H.1
Nilsson, M.2
-
4
-
-
0034161299
-
Endoderm development: From patterning to organogenesis
-
Grapin-Botton, A. & Melton, D. A. Endoderm development: from patterning to organogenesis. Trends Genet. 16, 124-130 (2000)
-
(2000)
Trends Genet
, vol.16
, pp. 124-130
-
-
Grapin-Botton, A.1
Melton, D.A.2
-
5
-
-
84891768365
-
Ensembl 2014
-
Flicek, P. et al. Ensembl 2014. Nucleic Acids Res. 42, D749-D755 (2014)
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D749-D755
-
-
Flicek, P.1
-
6
-
-
0019798972
-
Thyroid development and disorders of thyroid function in the newborn
-
Fisher, D. A. & Klein, A. H. Thyroid development and disorders of thyroid function in the newborn. N. Engl. J. Med. 304, 702-712 (1981)
-
(1981)
N. Engl. J. Med
, vol.304
, pp. 702-712
-
-
Fisher, D.A.1
Klein, A.H.2
-
7
-
-
84856445495
-
Detection and treatment of congenital hypothyroidism
-
Gruters, A. & Krude, H. Detection and treatment of congenital hypothyroidism. Nat. Rev. Endocrinol. 8, 104-113 (2011)
-
(2011)
Nat. Rev. Endocrinol
, vol.8
, pp. 104-113
-
-
Gruters, A.1
Krude, H.2
-
8
-
-
18844400822
-
Genetics of congenital hypothyroidism
-
Park, S. M. & Chatterjee, V. K. Genetics of congenital hypothyroidism. J. Med. Genet. 42, 379-389 (2005)
-
(2005)
J. Med. Genet
, vol.42
, pp. 379-389
-
-
Park, S.M.1
Chatterjee, V.K.2
-
9
-
-
0042632714
-
Development of the thyroid gland: Lessons from congenitally hypothyroid mice and men
-
Van Vliet, G. Development of the thyroid gland: lessons from congenitally hypothyroid mice and men. Clin. Genet. 63, 445-455 (2003)
-
(2003)
Clin. Genet
, vol.63
, pp. 445-455
-
-
Van Vliet, G.1
-
10
-
-
84871182766
-
Thyroid-specific transcription factors and their roles in thyroid cancer
-
Kimura, S. Thyroid-specific transcription factors and their roles in thyroid cancer. J. Thyroid Res. 2011, 710213 (2011)
-
(2011)
J. Thyroid Res
, vol.2011
, pp. 710213
-
-
Kimura, S.1
-
11
-
-
0024425390
-
A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
-
Civitareale, D., Lonigro, R., Sinclair, A. J. & Di Lauro, R. A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter. EMBO J. 8, 2537-2542 (1989)
-
(1989)
EMBO J
, vol.8
, pp. 2537-2542
-
-
Civitareale, D.1
Lonigro, R.2
Sinclair, A.J.3
Di Lauro, R.4
-
12
-
-
0025010740
-
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity
-
Guazzi, S. et al. Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J. 9, 3631-3639 (1990)
-
(1990)
EMBO J
, vol.9
, pp. 3631-3639
-
-
Guazzi, S.1
-
13
-
-
0026049382
-
Thyroid-specific enhancer-binding protein (T/EBP): CDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1
-
Mizuno, K., Gonzalez, F. J. & Kimura, S. Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1. Mol. Cell. Biol. 11, 4927-4933 (1991)
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 4927-4933
-
-
Mizuno, K.1
Gonzalez, F.J.2
Kimura, S.3
-
14
-
-
0028964324
-
Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells
-
Ikeda, K. et al. Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells. J. Biol. Chem. 270, 8108-8114 (1995)
-
(1995)
J. Biol. Chem
, vol.270
, pp. 8108-8114
-
-
Ikeda, K.1
-
15
-
-
0032513081
-
Structure of the human Nkx2.1 gene
-
Hamdan, H. et al. Structure of the human Nkx2.1 gene. Biochim. Biophys. Acta 1396, 336-348 (1998)
-
(1998)
Biochim. Biophys. Acta
, vol.1396
, pp. 336-348
-
-
Hamdan, H.1
-
16
-
-
0035944549
-
Immunohistochemical analyses of thyroid-specific enhancer-binding protein in the fetal and adult rat hypothalami and pituitary glands
-
Nakamura, K. et al. Immunohistochemical analyses of thyroid-specific enhancer-binding protein in the fetal and adult rat hypothalami and pituitary glands. Brain Res. Dev. Brain Res. 130, 159-166 (2001)
-
(2001)
Brain Res. Dev. Brain Res
, vol.130
, pp. 159-166
-
-
Nakamura, K.1
-
17
-
-
18344404449
-
TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation
-
Zannini, M. et al. TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J. 16, 3185-3197 (1997)
-
(1997)
EMBO J
, vol.16
, pp. 3185-3197
-
-
Zannini, M.1
-
18
-
-
0031149301
-
FKHL15, a new human member of the forkhead gene family located on chromosome 9q22
-
Chadwick, B. P., Obermayr, F. & Frischauf, A. M. FKHL15, a new human member of the forkhead gene family located on chromosome 9q22. Genomics 41, 390-396 (1997)
-
(1997)
Genomics
, vol.41
, pp. 390-396
-
-
Chadwick, B.P.1
Obermayr, F.2
Frischauf, A.M.3
-
19
-
-
35148815265
-
The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure
-
Cuesta, I., Zaret, K. S. & Santisteban, P. The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure. Mol. Cell. Biol. 27, 7302-7314 (2007)
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 7302-7314
-
-
Cuesta, I.1
Zaret, K.S.2
Santisteban, P.3
-
20
-
-
80455144479
-
Pioneer transcription factors: Establishing competence for gene expression
-
Zaret, K. S. & Carroll, J. S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25, 2227-2241 (2011)
-
(2011)
Genes Dev
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
21
-
-
0031820442
-
Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia
-
Clifton-Bligh, R. J. et al. Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia. Nat. Genet. 19, 399-401 (1998)
-
(1998)
Nat. Genet
, vol.19
, pp. 399-401
-
-
Clifton-Bligh, R.J.1
-
22
-
-
0242331182
-
Production and application of polyclonal antibody to human thyroid transcription factor 2 reveals thyroid transcription factor 2 protein expression in adult thyroid and hair follicles and prepubertal testis
-
Sequeira, M. et al. Production and application of polyclonal antibody to human thyroid transcription factor 2 reveals thyroid transcription factor 2 protein expression in adult thyroid and hair follicles and prepubertal testis. Thyroid 13, 927-932 (2003)
-
(2003)
Thyroid
, vol.13
, pp. 927-932
-
-
Sequeira, M.1
-
23
-
-
2442423841
-
FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma
-
Eichberger, T. et al. FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma. J. Invest. Dermatol. 122, 1180-1187 (2004)
-
(2004)
J. Invest. Dermatol
, vol.122
, pp. 1180-1187
-
-
Eichberger, T.1
-
24
-
-
0025084237
-
Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
-
Plachov, D. et al. Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development 110, 643-651 (1990)
-
(1990)
Development
, vol.110
, pp. 643-651
-
-
Plachov, D.1
-
25
-
-
0022904751
-
Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila
-
Bopp, D., Burri, M., Baumgartner, S., Frigerio, G. & Noll, M. Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila. Cell 47, 1033-1040 (1986)
-
(1986)
Cell
, vol.47
, pp. 1033-1040
-
-
Bopp, D.1
Burri, M.2
Baumgartner, S.3
Frigerio, G.4
Noll, M.5
-
26
-
-
81355148626
-
PAX2 and PAX8 expression in primary and metastatic Müllerian epithelial tumors: A comprehensive comparison
-
Ozcan, A., Liles, N., Coffey, D., Shen, S. S. & Truong, L. D. PAX2 and PAX8 expression in primary and metastatic Müllerian epithelial tumors: a comprehensive comparison. Am. J. Surg. Pathol. 35, 1837-1847 (2011)
-
(2011)
Am. J. Surg. Pathol
, vol.35
, pp. 1837-1847
-
-
Ozcan, A.1
Liles, N.2
Coffey, D.3
Shen, S.S.4
Truong, L.D.5
-
27
-
-
0026497586
-
PAX8, a human paired box gene: Isolation and expression in developing thyroid, kidney and Wilms' tumors
-
Poleev, A. et al. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors. Development 116, 611-623 (1992)
-
(1992)
Development
, vol.116
, pp. 611-623
-
-
Poleev, A.1
-
28
-
-
84904045314
-
NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer
-
Riesco-Eizaguirre, G. et al. NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer. J. Clin. Endocrinol. Metab. 99, E1199-E1208 (2014)
-
(2014)
J. Clin. Endocrinol. Metab
, vol.99
, pp. E1199-E1208
-
-
Riesco-Eizaguirre, G.1
-
29
-
-
0026462854
-
Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells
-
Crompton, M. R. et al. Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells. Nucleic Acids Res. 20, 5661-5667 (1992)
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 5661-5667
-
-
Crompton, M.R.1
-
30
-
-
0027205023
-
HEX: A novel homeobox gene expressed during haematopoiesis and conserved between mouse and human
-
Bedford, F. K., Ashworth, A., Enver, T. & Wiedemann, L. M. HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human. Nucleic Acids Res. 21, 1245-1249 (1993)
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 1245-1249
-
-
Bedford, F.K.1
Ashworth, A.2
Enver, T.3
Wiedemann, L.M.4
-
31
-
-
0031984524
-
Hex: A homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors
-
Thomas, P. Q., Brown, A. & Beddington, R. S. Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development 125, 85-94 (1998)
-
(1998)
Development
, vol.125
, pp. 85-94
-
-
Thomas, P.Q.1
Brown, A.2
Beddington, R.S.3
-
32
-
-
0033843244
-
Hex expression suggests a role in the development and function of organs derived from foregut endoderm
-
Bogue, C. W., Ganea, G. R., Sturm, E., Ianucci, R. & Jacobs, H. C. Hex expression suggests a role in the development and function of organs derived from foregut endoderm. Dev. Dyn. 219, 84-89 (2000)
-
(2000)
Dev. Dyn
, vol.219
, pp. 84-89
-
-
Bogue, C.W.1
Ganea, G.R.2
Sturm, E.3
Ianucci, R.4
Jacobs, H.C.5
-
33
-
-
79960721972
-
Minireview: Intrinsic and extrinsic factors in thyroid gland development: An update
-
De Felice, M. & Di Lauro, R. Minireview: Intrinsic and extrinsic factors in thyroid gland development: an update. Endocrinology 152, 2948-2956 (2011)
-
(2011)
Endocrinology
, vol.152
, pp. 2948-2956
-
-
De Felice, M.1
Di Lauro, R.2
-
35
-
-
0033049567
-
The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription
-
Ohno, M., Zannini, M., Levy, O., Carrasco, N. & di Lauro, R. The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol. Cell. Biol. 19, 2051-2060 (1999)
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 2051-2060
-
-
Ohno, M.1
Zannini, M.2
Levy, O.3
Carrasco, N.4
Di Lauro, R.5
-
36
-
-
0035202331
-
A unique combination of transcription factors controls differentiation of thyroid cells
-
Damante, G., Tell, G. & Di Lauro, R. A unique combination of transcription factors controls differentiation of thyroid cells. Prog. Nucleic Acid Res. Mol. Biol. 66, 307-356 (2001)
-
(2001)
Prog. Nucleic Acid Res. Mol. Biol
, vol.66
, pp. 307-356
-
-
Damante, G.1
Tell, G.2
Di Lauro, R.3
-
37
-
-
0034235464
-
Expression and function of the homeodomain-containing protein Hex in thyroid cells
-
Pellizzari, L. et al. Expression and function of the homeodomain-containing protein Hex in thyroid cells. Nucleic Acids Res. 28, 2503-2511 (2000)
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 2503-2511
-
-
Pellizzari, L.1
-
38
-
-
0037180569
-
Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland
-
Postiglione, M. P. et al. Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland. Proc. Natl Acad. Sci. USA 99, 15462-15467 (2002)
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 15462-15467
-
-
Postiglione, M.P.1
-
39
-
-
80052534205
-
Clinical review: The emerging cell biology of thyroid stem cells
-
Davies, T. F., Latif, R., Minsky, N. C. & Ma, R. Clinical review: The emerging cell biology of thyroid stem cells. J. Clin. Endocrinol. Metab. 96, 2692-2702 (2011)
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, pp. 2692-2702
-
-
Davies, T.F.1
Latif, R.2
Minsky, N.C.3
Ma, R.4
-
40
-
-
79551696195
-
Morphogenetics of early thyroid development
-
Fagman, H. & Nilsson, M. Morphogenetics of early thyroid development. J. Mol. Endocrinol. 46, R33-R42 (2011)
-
(2011)
J. Mol. Endocrinol
, vol.46
, pp. R33-R42
-
-
Fagman, H.1
Nilsson, M.2
-
41
-
-
0026340586
-
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
-
Lazzaro, D., Price, M., de Felice, M. & Di Lauro, R. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113, 1093-1104 (1991)
-
(1991)
Development
, vol.113
, pp. 1093-1104
-
-
Lazzaro, D.1
Price, M.2
De Felice, M.3
Di Lauro, R.4
-
42
-
-
0031730138
-
Identification of thyroid transcription factor-1 in C cells and parathyroid cells
-
Suzuki, K., Kobayashi, Y., Katoh, R., Kohn, L. D. & Kawaoi, A. Identification of thyroid transcription factor-1 in C cells and parathyroid cells. Endocrinology 139, 3014-3017 (1998)
-
(1998)
Endocrinology
, vol.139
, pp. 3014-3017
-
-
Suzuki, K.1
Kobayashi, Y.2
Katoh, R.3
Kohn, L.D.4
Kawaoi, A.5
-
43
-
-
0030057596
-
The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
-
Kimura, S. et al. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10, 60-69 (1996)
-
(1996)
Genes Dev
, vol.10
, pp. 60-69
-
-
Kimura, S.1
-
44
-
-
50849121011
-
Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors
-
Nobrega-Pereira, S. et al. Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron 59, 733-745 (2008)
-
(2008)
Neuron
, vol.59
, pp. 733-745
-
-
Nobrega-Pereira, S.1
-
45
-
-
34447131535
-
Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1
-
Tanaka, H. et al. Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1. Cancer Res. 67, 6007-6011 (2007)
-
(2007)
Cancer Res
, vol.67
, pp. 6007-6011
-
-
Tanaka, H.1
-
46
-
-
0032707150
-
Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia
-
Kimura, S., Ward, J. M. & Minoo, P. Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia. Biochimie 81, 321-327 (1999)
-
(1999)
Biochimie
, vol.81
, pp. 321-327
-
-
Kimura, S.1
Ward, J.M.2
Minoo, P.3
-
47
-
-
0033135419
-
Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos
-
Minoo, P., Su, G., Drum, H., Bringas, P. & Kimura, S. Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 209, 60-71 (1999)
-
(1999)
Dev. Biol
, vol.209
, pp. 60-71
-
-
Minoo, P.1
Su, G.2
Drum, H.3
Bringas, P.4
Kimura, S.5
-
48
-
-
9944248248
-
An integrated regulatory network controlling survival and migration in thyroid organogenesis
-
Parlato, R. et al. An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev. Biol. 276, 464-475 (2004)
-
(2004)
Dev. Biol
, vol.276
, pp. 464-475
-
-
Parlato, R.1
-
49
-
-
33746607692
-
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid
-
Kusakabe, T. et al. Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Mol. Endocrinol. 20, 1796-1809 (2006)
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 1796-1809
-
-
Kusakabe, T.1
-
50
-
-
0032841612
-
Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: Evidence for a transformation of the pallidum into the striatum
-
Sussel, L., Marin, O., Kimura, S. & Rubenstein, J. L. Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126, 3359-3370 (1999)
-
(1999)
Development
, vol.126
, pp. 3359-3370
-
-
Sussel, L.1
Marin, O.2
Kimura, S.3
Rubenstein, J.L.4
-
51
-
-
84892748994
-
Lung development: Orchestrating the generation and regeneration of a complex organ
-
Herriges, M. & Morrisey, E. E. Lung development: orchestrating the generation and regeneration of a complex organ. Development 141, 502-513 (2014)
-
(2014)
Development
, vol.141
, pp. 502-513
-
-
Herriges, M.1
Morrisey, E.E.2
-
52
-
-
44449127533
-
NKX2.1 specifies cortical interneuron fate by activating Lhx6
-
Du, T., Xu, Q., Ocbina, P. J. & Anderson, S. A. NKX2.1 specifies cortical interneuron fate by activating Lhx6. Development 135, 1559-1567 (2008)
-
(2008)
Development
, vol.135
, pp. 1559-1567
-
-
Du, T.1
Xu, Q.2
Ocbina, P.J.3
Anderson, S.A.4
-
53
-
-
50849093561
-
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes
-
Butt, S. J. et al. The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron 59, 722-732 (2008)
-
(2008)
Neuron
, vol.59
, pp. 722-732
-
-
Butt, S.J.1
-
54
-
-
0036022315
-
Distribution of the titf2/foxe1 gene product is consistent with an important role in the development of foregut endoderm palate and hair
-
Dathan, N., Parlato, R., Rosica, A., De Felice, M. & Di Lauro, R. Distribution of the titf2/foxe1 gene product is consistent with an important role in the development of foregut endoderm, palate, and hair. Dev. Dyn. 224, 450-456 (2002)
-
(2002)
Dev. Dyn
, vol.224
, pp. 450-456
-
-
Dathan, N.1
Parlato, R.2
Rosica, A.3
De Felice, M.4
Di Lauro, R.5
-
55
-
-
17344366813
-
A mouse model for hereditary thyroid dysgenesis and cleft palate
-
De Felice, M. et al. A mouse model for hereditary thyroid dysgenesis and cleft palate. Nat. Genet. 19, 395-398 (1998)
-
(1998)
Nat. Genet
, vol.19
, pp. 395-398
-
-
De Felice, M.1
-
56
-
-
30744475470
-
The developing mouse thyroid: Embryonic vessel contacts and parenchymal growth pattern during specification, budding, migration, and lobulation
-
Fagman, H., Andersson, L. & Nilsson, M. The developing mouse thyroid: embryonic vessel contacts and parenchymal growth pattern during specification, budding, migration, and lobulation. Dev. Dyn. 235, 444-455 (2006)
-
(2006)
Dev. Dyn
, vol.235
, pp. 444-455
-
-
Fagman, H.1
Andersson, L.2
Nilsson, M.3
-
57
-
-
0031777309
-
Follicular cells of the thyroid gland require Pax8 gene function
-
Mansouri, A., Chowdhury, K. & Gruss, P. Follicular cells of the thyroid gland require Pax8 gene function. Nat. Genet. 19, 87-90 (1998)
-
(1998)
Nat. Genet
, vol.19
, pp. 87-90
-
-
Mansouri, A.1
Chowdhury, K.2
Gruss, P.3
-
58
-
-
33947381472
-
Male congenital hypothyroid Pax8-/-mice are infertile despite adequate treatment with thyroid hormone
-
Wistuba, J. et al. Male congenital hypothyroid Pax8-/-mice are infertile despite adequate treatment with thyroid hormone. J. Endocrinol. 192, 99-109 (2007)
-
(2007)
J. Endocrinol
, vol.192
, pp. 99-109
-
-
Wistuba, J.1
-
59
-
-
82455175320
-
Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning
-
Fagman, H. et al. Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning. Dev. Biol. 359, 163-175 (2011)
-
(2011)
Dev. Biol
, vol.359
, pp. 163-175
-
-
Fagman, H.1
-
60
-
-
0025118546
-
Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system
-
Dressler, G. R., Deutsch, U., Chowdhury, K., Nornes, H. O. & Gruss, P. Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development 109, 787-795 (1990)
-
(1990)
Development
, vol.109
, pp. 787-795
-
-
Dressler, G.R.1
Deutsch, U.2
Chowdhury, K.3
Nornes, H.O.4
Gruss, P.5
-
61
-
-
0027053496
-
Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development
-
Asano, M. & Gruss, P. Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development. Mech. Dev. 39, 29-39 (1992)
-
(1992)
Mech. Dev
, vol.39
, pp. 29-39
-
-
Asano, M.1
Gruss, P.2
-
62
-
-
0037112237
-
Nephric lineage specification by Pax2 and Pax8
-
Bouchard, M., Souabni, A., Mandler, M., Neubuser, A. & Busslinger, M. Nephric lineage specification by Pax2 and Pax8. Genes Dev. 16, 2958-2970 (2002)
-
(2002)
Genes Dev
, vol.16
, pp. 2958-2970
-
-
Bouchard, M.1
Souabni, A.2
Mandler, M.3
Neubuser, A.4
Busslinger, M.5
-
63
-
-
12944305958
-
Pax8 has a key role in thyroid cell differentiation
-
Pasca di Magliano, M., Di Lauro, R. & Zannini, M. Pax8 has a key role in thyroid cell differentiation. Proc. Natl Acad. Sci. USA 97, 13144-13149 (2000)
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 13144-13149
-
-
Pasca Di Magliano, M.1
Di Lauro, R.2
Zannini, M.3
-
64
-
-
0034124779
-
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation
-
Martinez Barbera, J. P. et al. The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development 127, 2433-2445 (2000)
-
(2000)
Development
, vol.127
, pp. 2433-2445
-
-
Martinez Barbera, J.P.1
-
65
-
-
30544442260
-
Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development
-
Bort, R., Signore, M., Tremblay, K., Martinez Barbera, J. P. & Zaret, K. S. Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development. Dev. Biol. 290, 44-56 (2006)
-
(2006)
Dev. Biol
, vol.290
, pp. 44-56
-
-
Bort, R.1
Signore, M.2
Tremblay, K.3
Martinez Barbera, J.P.4
Zaret, K.S.5
-
66
-
-
84868374724
-
Generation of functional thyroid from embryonic stem cells
-
Antonica, F. et al. Generation of functional thyroid from embryonic stem cells. Nature 491, 66-71 (2012)
-
(2012)
Nature
, vol.491
, pp. 66-71
-
-
Antonica, F.1
-
67
-
-
84862216535
-
Genome-wide analysis of Pax8 binding provides new insights into thyroid functions
-
Ruiz-Llorente, S. et al. Genome-wide analysis of Pax8 binding provides new insights into thyroid functions. BMC Genomics 13, 147 (2012)
-
(2012)
BMC Genomics
, vol.13
, pp. 147
-
-
Ruiz-Llorente, S.1
-
68
-
-
0025051411
-
The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors
-
Sinclair, A. J., Lonigro, R., Civitareale, D., Ghibelli, L. & Di Lauro, R. The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors. Eur. J. Biochem. 193, 311-318 (1990)
-
(1990)
Eur. J. Biochem
, vol.193
, pp. 311-318
-
-
Sinclair, A.J.1
Lonigro, R.2
Civitareale, D.3
Ghibelli, L.4
Di Lauro, R.5
-
69
-
-
0028786558
-
Redundant domains contribute to the transcriptional activity of the thyroid transcription factor 1
-
De Felice, M., Damante, G., Zannini, M., Francis-Lang, H. & Di Lauro, R. Redundant domains contribute to the transcriptional activity of the thyroid transcription factor 1. J. Biol. Chem. 270, 26649-26656 (1995)
-
(1995)
J. Biol. Chem
, vol.270
, pp. 26649-26656
-
-
De Felice, M.1
Damante, G.2
Zannini, M.3
Francis-Lang, H.4
Di Lauro, R.5
-
70
-
-
57749190560
-
TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation
-
Di Palma, T. et al. TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation. Exp. Cell Res. 315, 162-175 (2009)
-
(2009)
Exp. Cell Res
, vol.315
, pp. 162-175
-
-
Di Palma, T.1
-
71
-
-
0026593301
-
Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression
-
Francis-Lang, H., Price, M., Polycarpou-Schwarz, M. & Di Lauro, R. Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Mol. Cell. Biol. 12, 576-588 (1992)
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 576-588
-
-
Francis-Lang, H.1
Price, M.2
Polycarpou-Schwarz, M.3
Di Lauro, R.4
-
72
-
-
85003066115
-
Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene
-
Civitareale, D., Castelli, M. P., Falasca, P. & Saiardi, A. Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene. Mol. Endocrinol. 7, 1589-1595 (1993)
-
(1993)
Mol. Endocrinol
, vol.7
, pp. 1589-1595
-
-
Civitareale, D.1
Castelli, M.P.2
Falasca, P.3
Saiardi, A.4
-
73
-
-
0027943177
-
Identification of a novel insulin-responsive element in the rat thyrotropin receptor promoter
-
Shimura, Y., Shimura, H., Ohmori, M., Ikuyama, S. & Kohn, L. D. Identification of a novel insulin-responsive element in the rat thyrotropin receptor promoter. J. Biol. Chem. 269, 31908-31914 (1994)
-
(1994)
J. Biol. Chem
, vol.269
, pp. 31908-31914
-
-
Shimura, Y.1
Shimura, H.2
Ohmori, M.3
Ikuyama, S.4
Kohn, L.D.5
-
74
-
-
0030880728
-
Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene
-
Endo, T. et al. Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene. Mol. Endocrinol. 11, 1747-1755 (1997)
-
(1997)
Mol. Endocrinol
, vol.11
, pp. 1747-1755
-
-
Endo, T.1
-
75
-
-
0037389787
-
Thyroid-specific transcription factors control Hex promoter activity
-
Puppin, C. et al. Thyroid-specific transcription factors control Hex promoter activity. Nucleic Acids Res. 31, 1845-1852 (2003)
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1845-1852
-
-
Puppin, C.1
-
76
-
-
27644592904
-
Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells
-
Dentice, M. et al. Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells. Mol. Cell. Biol. 25, 10171-10182 (2005)
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10171-10182
-
-
Dentice, M.1
-
77
-
-
84860470401
-
Functional inactivation of thyroid transcription factor-1 in PCCl3 thyroid cells
-
Christophe-Hobertus, C., Lefort, A., Libert, F. & Christophe, D. Functional inactivation of thyroid transcription factor-1 in PCCl3 thyroid cells. Mol. Cell. Endocrinol. 358, 36-45 (2012)
-
(2012)
Mol. Cell. Endocrinol
, vol.358
, pp. 36-45
-
-
Christophe-Hobertus, C.1
Lefort, A.2
Libert, F.3
Christophe, D.4
-
78
-
-
0031764280
-
Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: Evidence of autoregulation
-
Oguchi, H. & Kimura, S. Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: evidence of autoregulation. Endocrinology 139, 1999-2006 (1998)
-
(1998)
Endocrinology
, vol.139
, pp. 1999-2006
-
-
Oguchi, H.1
Kimura, S.2
-
79
-
-
0031590297
-
Transcription of the thyroid transcription factor-1 (TTF-1) gene from a newly defined start site: Positive regulation by TTF-1 in the thyroid
-
Nakazato, M., Endo, T., Saito, T., Harii, N. & Onaya, T. Transcription of the thyroid transcription factor-1 (TTF-1) gene from a newly defined start site: positive regulation by TTF-1 in the thyroid. Biochem. Biophys. Res. Commun. 238, 748-752 (1997)
-
(1997)
Biochem. Biophys. Res. Commun
, vol.238
, pp. 748-752
-
-
Nakazato, M.1
Endo, T.2
Saito, T.3
Harii, N.4
Onaya, T.5
-
80
-
-
33746629382
-
Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction
-
D'Andrea, B. et al. Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction. Mol. Endocrinol. 20, 1810-1824 (2006)
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 1810-1824
-
-
D'andrea, B.1
-
81
-
-
0028148114
-
Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain
-
Damante, G. et al. Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain. Nucleic Acids Res. 22, 3075-3083 (1994)
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3075-3083
-
-
Damante, G.1
-
82
-
-
0036789946
-
Sequence-specific DNA binding by the vnd/NK-2 homeodomain of Drosophila
-
Wang, L. H., Chmelik, R. & Nirenberg, M. Sequence-specific DNA binding by the vnd/NK-2 homeodomain of Drosophila. Proc. Natl Acad. Sci. USA 99, 12721-12726 (2002)
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 12721-12726
-
-
Wang, L.H.1
Chmelik, R.2
Nirenberg, M.3
-
83
-
-
84874788481
-
Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
-
Watanabe, H. et al. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. Genes Dev. 27, 197-210 (2013)
-
(2013)
Genes Dev
, vol.27
, pp. 197-210
-
-
Watanabe, H.1
-
84
-
-
60549094652
-
Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung
-
Boggaram, V. Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung. Clin. Sci. (Lond.) 116, 27-35 (2009)
-
(2009)
Clin. Sci. (Lond.)
, vol.116
, pp. 27-35
-
-
Boggaram, V.1
-
85
-
-
84857189404
-
MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis
-
Hosono, Y. et al. MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis. EMBO J. 31, 481-493 (2012)
-
(2012)
EMBO J
, vol.31
, pp. 481-493
-
-
Hosono, Y.1
-
86
-
-
0442323558
-
NKX2.1 regulates transcription of the gene for human bone morphogenetic protein-4 in lung epithelial cells
-
Zhu, N. L., Li, C., Xiao, J. & Minoo, P. NKX2.1 regulates transcription of the gene for human bone morphogenetic protein-4 in lung epithelial cells. Gene 327, 25-36 (2004)
-
(2004)
Gene
, vol.327
, pp. 25-36
-
-
Zhu, N.L.1
Li, C.2
Xiao, J.3
Minoo, P.4
-
87
-
-
84865262164
-
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1
-
Runkle, E. A. et al. Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1) J. Biol. Chem. 287. 28790-28801 (2012)
-
(2012)
J. Biol. Chem
, vol.287
, pp. 28790-28801
-
-
Runkle, E.A.1
-
88
-
-
84855369392
-
Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors
-
Tagne, J. B. et al. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors. PLoS ONE 7, e29907 (2012)
-
(2012)
PLoS ONE
, vol.7
, pp. e29907
-
-
Tagne, J.B.1
-
89
-
-
70350070157
-
Transcriptional regulation of RET by Nkx2-1, Phox2b, Sox10, and Pax3
-
Leon, T. Y. et al. Transcriptional regulation of RET by Nkx2-1, Phox2b, Sox10, and Pax3. J. Pediatr. Surg. 44, 1904-1912 (2009)
-
(2009)
J. Pediatr. Surg
, vol.44
, pp. 1904-1912
-
-
Leon, T.Y.1
-
90
-
-
77952940255
-
Large scale analysis of transcription factor TTF-1/NKX2.1 target genes in GnRH secreting cell line GT1-7
-
Provenzano, C., Pascucci, B., Lupari, E. & Civitareale, D. Large scale analysis of transcription factor TTF-1/NKX2.1 target genes in GnRH secreting cell line GT1-7. Mol. Cell. Endocrinol. 323, 215-223 (2010)
-
(2010)
Mol. Cell. Endocrinol
, vol.323
, pp. 215-223
-
-
Provenzano, C.1
Pascucci, B.2
Lupari, E.3
Civitareale, D.4
-
91
-
-
84883476818
-
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
-
Satoh, A. et al. Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab. 18, 416-430 (2013)
-
(2013)
Cell Metab
, vol.18
, pp. 416-430
-
-
Satoh, A.1
-
92
-
-
38749120924
-
TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin
-
Pelizzoli, R. et al. TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin. Int. J. Dev. Biol. 52, 55-62 (2008)
-
(2008)
Int. J. Dev. Biol
, vol.52
, pp. 55-62
-
-
Pelizzoli, R.1
-
93
-
-
0026662799
-
Insulin and insulin-like growth factor i regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter
-
Santisteban, P., Acebron, A., Polycarpou-Schwarz, M. & Di Lauro, R. Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter. Mol. Endocrinol. 6, 1310-1317 (1992)
-
(1992)
Mol. Endocrinol
, vol.6
, pp. 1310-1317
-
-
Santisteban, P.1
Acebron, A.2
Polycarpou-Schwarz, M.3
Di Lauro, R.4
-
94
-
-
0027507599
-
Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity
-
Aza-Blanc, P., Di Lauro, R. & Santisteban, P. Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity. Mol. Endocrinol. 7, 1297-1306 (1993)
-
(1993)
Mol. Endocrinol
, vol.7
, pp. 1297-1306
-
-
Aza-Blanc, P.1
Di Lauro, R.2
Santisteban, P.3
-
95
-
-
0030770823
-
Transcriptional control of the forkhead thyroid transcription factor TTF-2 by thyrotropin, insulin, and insulin-like growth factor i
-
Ortiz, L., Zannini, M., Di Lauro, R. & Santisteban, P. Transcriptional control of the forkhead thyroid transcription factor TTF-2 by thyrotropin, insulin, and insulin-like growth factor I. J. Biol. Chem. 272, 23334-23339 (1997)
-
(1997)
J. Biol. Chem
, vol.272
, pp. 23334-23339
-
-
Ortiz, L.1
Zannini, M.2
Di Lauro, R.3
Santisteban, P.4
-
96
-
-
0034682927
-
The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor
-
Perrone, L., Pasca di Magliano, M., Zannini, M. & Di Lauro, R. The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor. Biochem. Biophys. Res. Commun. 275, 203-208 (2000)
-
(2000)
Biochem. Biophys. Res. Commun
, vol.275
, pp. 203-208
-
-
Perrone, L.1
Pasca Di Magliano, M.2
Zannini, M.3
Di Lauro, R.4
-
97
-
-
0033591246
-
The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription
-
Ortiz, L., Aza-Blanc, P., Zannini, M., Cato, A. C. & Santisteban, P. The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription. J. Biol. Chem. 274, 15213-15221 (1999)
-
(1999)
J. Biol. Chem
, vol.274
, pp. 15213-15221
-
-
Ortiz, L.1
Aza-Blanc, P.2
Zannini, M.3
Cato, A.C.4
Santisteban, P.5
-
98
-
-
84877692624
-
New insights into FoxE1 functions: Identification of direct FoxE1 targets in thyroid cells
-
Fernandez, L. P., Lopez-Marquez, A., Martinez, A. M., Gomez-Lopez, G. & Santisteban, P. New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells. PLoS ONE 8, e62849 (2013)
-
(2013)
PLoS ONE
, vol.8
, pp. e62849
-
-
Fernandez, L.P.1
Lopez-Marquez, A.2
Martinez, A.M.3
Gomez-Lopez, G.4
Santisteban, P.5
-
99
-
-
3042656861
-
TTF-2 stimulates expression of 17 genes, including one novel thyroid-specific gene which might be involved in thyroid development
-
Hishinuma, A., Ohmika, N., Namatame, T. & Ieiri, T. TTF-2 stimulates expression of 17 genes, including one novel thyroid-specific gene which might be involved in thyroid development. Mol. Cell. Endocrinol. 221, 33-46 (2004)
-
(2004)
Mol. Cell. Endocrinol
, vol.221
, pp. 33-46
-
-
Hishinuma, A.1
Ohmika, N.2
Namatame, T.3
Ieiri, T.4
-
100
-
-
79551585995
-
MSX1 and TGF-β3 are novel target genes functionally regulated by FOXE1
-
Venza, I. et al. MSX1 and TGF-β3 are novel target genes functionally regulated by FOXE1. Hum. Mol. Genet. 20, 1016-1025 (2010)
-
(2010)
Hum. Mol. Genet
, vol.20
, pp. 1016-1025
-
-
Venza, I.1
-
101
-
-
0026738482
-
Pax-8 a paired domain-containing protein binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters
-
Zannini, M., Francis-Lang, H., Plachov, D. & Di Lauro, R. Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters. Mol. Cell. Biol. 12, 4230-4241 (1992)
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 4230-4241
-
-
Zannini, M.1
Francis-Lang, H.2
Plachov, D.3
Di Lauro, R.4
-
102
-
-
0032055851
-
PAX 8 activates the enhancer of the human thyroperoxidase gene
-
Esposito, C., Miccadei, S., Saiardi, A. & Civitareale, D. PAX 8 activates the enhancer of the human thyroperoxidase gene. Biochem. J. 331 (Pt 1), 37-40 (1998)
-
(1998)
Biochem. J
, vol.331
, pp. 37-40
-
-
Esposito, C.1
Miccadei, S.2
Saiardi, A.3
Civitareale, D.4
-
103
-
-
0027426925
-
DNA sequence recognition by Pax proteins: Bipartite structure of the paired domain and its binding site
-
Czerny, T., Schaffner, G. & Busslinger, M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7, 2048-2061 (1993)
-
(1993)
Genes Dev
, vol.7
, pp. 2048-2061
-
-
Czerny, T.1
Schaffner, G.2
Busslinger, M.3
-
104
-
-
0029873480
-
A network of specific minor-groove contacts is a common characteristic of paired-domain-DNA interactions
-
Pellizzari, L., Fabbro, D., Lonigro, R., Di Lauro, R. & Damante, G. A network of specific minor-groove contacts is a common characteristic of paired-domain-DNA interactions. Biochem. J. 315 (Pt 2), 363-367 (1996)
-
(1996)
Biochem. J
, vol.315
, pp. 363-367
-
-
Pellizzari, L.1
Fabbro, D.2
Lonigro, R.3
Di Lauro, R.4
Damante, G.5
-
105
-
-
0037474242
-
The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription
-
Di Palma, T. et al. The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription. J. Biol. Chem. 278, 3395-3402 (2003)
-
(2003)
J. Biol. Chem
, vol.278
, pp. 3395-3402
-
-
Di Palma, T.1
-
106
-
-
22444436353
-
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity
-
Grasberger, H. et al. Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. Mol. Endocrinol. 19, 1779-1791 (2005)
-
(2005)
Mol. Endocrinol
, vol.19
, pp. 1779-1791
-
-
Grasberger, H.1
-
107
-
-
0034602249
-
Role for p300 in Pax 8 induction of thyroperoxidase gene expression
-
De Leo, R., Miccadei, S., Zammarchi, E. & Civitareale, D. Role for p300 in Pax 8 induction of thyroperoxidase gene expression. J. Biol. Chem. 275, 34100-34105 (2000)
-
(2000)
J. Biol. Chem
, vol.275
, pp. 34100-34105
-
-
De Leo, R.1
Miccadei, S.2
Zammarchi, E.3
Civitareale, D.4
-
108
-
-
84899755132
-
Wnt-independent role of β-catenin in thyroid cell proliferation and differentiation
-
Sastre-Perona, A. & Santisteban, P. Wnt-independent role of β-catenin in thyroid cell proliferation and differentiation. Mol. Endocrinol. 28, 681-695 (2014)
-
(2014)
Mol. Endocrinol
, vol.28
, pp. 681-695
-
-
Sastre-Perona, A.1
Santisteban, P.2
-
109
-
-
1142273379
-
Functional interaction among thyroid-specific transcription factors: Pax8 regulates the activity of Hex promoter
-
Puppin, C. et al. Functional interaction among thyroid-specific transcription factors: Pax8 regulates the activity of Hex promoter. Mol. Cell. Endocrinol. 214, 117-125 (2004)
-
(2004)
Mol. Cell. Endocrinol
, vol.214
, pp. 117-125
-
-
Puppin, C.1
-
110
-
-
80053103995
-
Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis
-
Di Palma, T. et al. Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis. PLoS ONE 6, e25162 (2011)
-
(2011)
PLoS ONE
, vol.6
, pp. e25162
-
-
Di Palma, T.1
-
111
-
-
33846333871
-
Human thyroid oxidases genes promoter activity in thyrocytes does not appear to be functionally dependent on thyroid transcription factor-1 or Pax8
-
Christophe-Hobertus, C. & Christophe, D. Human thyroid oxidases genes promoter activity in thyrocytes does not appear to be functionally dependent on thyroid transcription factor-1 or Pax8. Mol. Cell. Endocrinol. 264, 157-163 (2007)
-
(2007)
Mol. Cell. Endocrinol
, vol.264
, pp. 157-163
-
-
Christophe-Hobertus, C.1
Christophe, D.2
-
112
-
-
84875731143
-
Functional analysis of the murine Pax8 promoter reveals autoregulation and the presence of a novel thyroid-specific DNA-binding activity
-
di Gennaro, A., Spadaro, O., Baratta, M. G., De Felice, M. & Di Lauro, R. Functional analysis of the murine Pax8 promoter reveals autoregulation and the presence of a novel thyroid-specific DNA-binding activity. Thyroid 23, 488-496 (2013)
-
(2013)
Thyroid
, vol.23
, pp. 488-496
-
-
Di Gennaro, A.1
Spadaro, O.2
Baratta, M.G.3
De Felice, M.4
Di Lauro, R.5
-
113
-
-
0028809870
-
Loss of p53 function through PAX-mediated transcriptional repression
-
Stuart, E. T., Haffner, R., Oren, M. & Gruss, P. Loss of p53 function through PAX-mediated transcriptional repression. EMBO J. 14, 5638-5645 (1995)
-
(1995)
EMBO J
, vol.14
, pp. 5638-5645
-
-
Stuart, E.T.1
Haffner, R.2
Oren, M.3
Gruss, P.4
-
114
-
-
0029756801
-
PAX8-mediated activation of the wt1 tumor suppressor gene
-
Dehbi, M. & Pelletier, J. PAX8-mediated activation of the wt1 tumor suppressor gene. EMBO J. 15, 4297-4306 (1996)
-
(1996)
EMBO J
, vol.15
, pp. 4297-4306
-
-
Dehbi, M.1
Pelletier, J.2
-
115
-
-
82455209048
-
PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein
-
Li, C. G., Nyman, J. E., Braithwaite, A. W. & Eccles, M. R. PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein. Oncogene 30, 4824-4834 (2011)
-
(2011)
Oncogene
, vol.30
, pp. 4824-4834
-
-
Li, C.G.1
Nyman, J.E.2
Braithwaite, A.W.3
Eccles, M.R.4
-
116
-
-
84881072034
-
Pax8 has a critical role in epithelial cell survival and proliferation
-
Di Palma, T. et al. Pax8 has a critical role in epithelial cell survival and proliferation. Cell Death Dis. 4, e729 (2013)
-
(2013)
Cell Death Dis
, vol.4
, pp. e729
-
-
Di Palma, T.1
-
117
-
-
8444234265
-
A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels
-
Hallaq, H. et al. A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels. Development 131, 5197-5209 (2004)
-
(2004)
Development
, vol.131
, pp. 5197-5209
-
-
Hallaq, H.1
-
118
-
-
0033739229
-
Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish
-
Liao, W., Ho, C. Y., Yan, Y. L., Postlethwait, J. & Stainier, D. Y. Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127, 4303-4313 (2000)
-
(2000)
Development
, vol.127
, pp. 4303-4313
-
-
Liao, W.1
Ho, C.Y.2
Yan, Y.L.3
Postlethwait, J.4
Stainier, D.Y.5
-
119
-
-
33750326784
-
Hex acts with β-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal
-
Zamparini, A. L. et al. Hex acts with β-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal. Development 133, 3709-3722 (2006)
-
(2006)
Development
, vol.133
, pp. 3709-3722
-
-
Zamparini, A.L.1
-
120
-
-
84887547270
-
PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin
-
Kershaw, R. M., Siddiqui, Y. H., Roberts, D., Jayaraman, P. S. & Gaston, K. PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin. Oncogene http://dx.doi.org/10.1038/onc.2013.496.
-
Oncogene
-
-
Kershaw, R.M.1
Siddiqui, Y.H.2
Roberts, D.3
Jayaraman, P.S.4
Gaston, K.5
-
121
-
-
84888805501
-
Mechanisms of thyroid development and dysgenesis: An analysis based on developmental stages and concurrent embryonic anatomy
-
Nilsson, M. & Fagman, H. Mechanisms of thyroid development and dysgenesis: an analysis based on developmental stages and concurrent embryonic anatomy. Curr. Top. Dev. Biol. 106, 123-170 (2013)
-
(2013)
Curr. Top. Dev. Biol
, vol.106
, pp. 123-170
-
-
Nilsson, M.1
Fagman, H.2
-
122
-
-
84885657237
-
The molecular causes of thyroid dysgenesis: A systematic review
-
Nettore, I. C., Cacace, V., De Fusco, C., Colao, A. & Macchia, P. E. The molecular causes of thyroid dysgenesis: a systematic review. J. Endocrinol. Invest. 36, 654-664 (2013)
-
(2013)
J. Endocrinol. Invest
, vol.36
, pp. 654-664
-
-
Nettore, I.C.1
Cacace, V.2
De Fusco, C.3
Colao, A.4
Macchia, P.E.5
-
123
-
-
27844552888
-
Thyroid dysgenesis: Multigenic or epigenetic. or both?
-
Vassart, G. & Dumont, J. E. Thyroid dysgenesis: multigenic or epigenetic. or both? Endocrinology 146, 5035-5037 (2005)
-
(2005)
Endocrinology
, vol.146
, pp. 5035-5037
-
-
Vassart, G.1
Dumont, J.E.2
-
124
-
-
35148864922
-
Possible non-Mendelian mechanisms of thyroid dysgenesis
-
Deladoey, J., Vassart, G. & Van Vliet, G. Possible non-Mendelian mechanisms of thyroid dysgenesis. Endocr. Dev. 10, 29-42 (2007)
-
(2007)
Endocr. Dev
, vol.10
, pp. 29-42
-
-
Deladoey, J.1
Vassart, G.2
Van Vliet, G.3
-
125
-
-
78149433455
-
Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands
-
Abu-Khudir, R. et al. Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands. PLoS ONE 5, e13420 (2010)
-
(2010)
PLoS ONE
, vol.5
, pp. e13420
-
-
Abu-Khudir, R.1
-
126
-
-
84878872683
-
Identification and functional characterization of a novel mutation in the NKX2-1 gene: Comparison with the data in the literature
-
Nettore, I. C. et al. Identification and functional characterization of a novel mutation in the NKX2-1 gene: comparison with the data in the literature. Thyroid 23, 675-682 (2013)
-
(2013)
Thyroid
, vol.23
, pp. 675-682
-
-
Nettore, I.C.1
-
127
-
-
84901454226
-
Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum
-
Thorwarth, A. et al. Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum. J. Med. Genet. 51, 375-387 (2014)
-
(2014)
J. Med. Genet
, vol.51
, pp. 375-387
-
-
Thorwarth, A.1
-
129
-
-
0036181474
-
Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency
-
Krude, H. et al. Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency. J. Clin. Invest. 109, 475-480 (2002)
-
(2002)
J. Clin. Invest
, vol.109
, pp. 475-480
-
-
Krude, H.1
-
130
-
-
12144277942
-
Brain-Thyroid-Lung syndrome: A patient with a severe multi-system disorder due to a de novo mutation in the thyroid transcription factor 1 gene
-
Willemsen, M. A. et al. Brain-Thyroid-Lung syndrome: a patient with a severe multi-system disorder due to a de novo mutation in the thyroid transcription factor 1 gene. Eur. J. Pediatr. 164, 28-30 (2005)
-
(2005)
Eur. J. Pediatr
, vol.164
, pp. 28-30
-
-
Willemsen, M.A.1
-
131
-
-
66149122629
-
Five new TTF1/NKX2.1 mutations in brain-lung-thyroid syndrome: Rescue by PAX8 synergism in one case
-
Carre, A. et al. Five new TTF1/NKX2.1 mutations in brain-lung-thyroid syndrome: rescue by PAX8 synergism in one case. Hum. Mol. Genet. 18, 2266-2276 (2009)
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 2266-2276
-
-
Carre, A.1
-
132
-
-
33646411749
-
Functional study of a novel single deletion in the TITF1/NKX2.1 homeobox gene that produces congenital hypothyroidism and benign chorea but not pulmonary distress
-
Moya, C. M. et al. Functional study of a novel single deletion in the TITF1/NKX2.1 homeobox gene that produces congenital hypothyroidism and benign chorea but not pulmonary distress. J. Clin. Endocrinol. Metab. 91, 1832-1841 (2006)
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 1832-1841
-
-
Moya, C.M.1
-
133
-
-
75149175193
-
NKX2-1 mutations leading to surfactant protein promoter dysregulation cause interstitial lung disease in Brain-lung-thyroid syndrome
-
Guillot, L. et al. NKX2-1 mutations leading to surfactant protein promoter dysregulation cause interstitial lung disease in "Brain-Lung-Thyroid Syndrome". Hum. Mutat. 31, E1146-E1162 (2010)
-
(2010)
Hum. Mutat
, vol.31
, pp. E1146-E1162
-
-
Guillot, L.1
-
134
-
-
77952304081
-
Spectrum of Human Foxe1/TTF2 Mutations
-
Castanet, M. & Polak, M. Spectrum of Human Foxe1/TTF2 Mutations. Horm. Res. Paediatr. 73, 423-429 (2010)
-
(2010)
Horm. Res. Paediatr
, vol.73
, pp. 423-429
-
-
Castanet, M.1
Polak, M.2
-
135
-
-
84898468689
-
A novel FOXE1 mutation (R73S) in Bamforth-Lazarus syndrome causing increased thyroidal gene expression
-
Carre, A. et al. A novel FOXE1 mutation (R73S) in Bamforth-Lazarus syndrome causing increased thyroidal gene expression. Thyroid 24, 649-654 (2014)
-
(2014)
Thyroid
, vol.24
, pp. 649-654
-
-
Carre, A.1
-
136
-
-
36348935021
-
Polymorphic length of FOXE1 alanine stretch: Evidence for genetic susceptibility to thyroid dysgenesis
-
Carre, A. et al. Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis. Hum. Genet. 122, 467-476 (2007)
-
(2007)
Hum. Genet
, vol.122
, pp. 467-476
-
-
Carre, A.1
-
137
-
-
33947512641
-
TTF-2/FOXE1 gene polymorphisms in Sicilian patients with permanent primary congenital hypothyroidism
-
Santarpia, L. et al. TTF-2/FOXE1 gene polymorphisms in Sicilian patients with permanent primary congenital hypothyroidism. J. Endocrinol. Invest. 30, 13-19 (2007)
-
(2007)
J. Endocrinol. Invest
, vol.30
, pp. 13-19
-
-
Santarpia, L.1
-
138
-
-
79955702016
-
FOXE1 polyalanine tract length polymorphism in patients with thyroid hemiagenesis and subjects with normal thyroid
-
Szczepanek, E. et al. FOXE1 polyalanine tract length polymorphism in patients with thyroid hemiagenesis and subjects with normal thyroid. Horm. Res. Paediatr. 75, 329-334 (2011)
-
(2011)
Horm. Res. Paediatr
, vol.75
, pp. 329-334
-
-
Szczepanek, E.1
-
139
-
-
5444272310
-
Polyalanine expansions in human
-
Amiel, J., Trochet, D., Clement-Ziza, M., Munnich, A. & Lyonnet, S. Polyalanine expansions in human. Hum. Mol. Genet. 13 (Suppl. 2), R235-R243 (2004)
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. R235-R243
-
-
Amiel, J.1
Trochet, D.2
Clement-Ziza, M.3
Munnich, A.4
Lyonnet, S.5
-
140
-
-
58149263375
-
Clinical and molecular analysis of thyroid hypoplasia: A population-based approach in southern Brazil
-
Ramos, H. E. et al. Clinical and molecular analysis of thyroid hypoplasia: a population-based approach in southern Brazil. Thyroid 19, 61-68 (2009)
-
(2009)
Thyroid
, vol.19
, pp. 61-68
-
-
Ramos, H.E.1
-
141
-
-
79956331473
-
Mutations in the NKX2.5 gene and the PAX8 promoter in a girl with thyroid dysgenesis
-
Hermanns, P., Grasberger, H., Refetoff, S. & Pohlenz, J. Mutations in the NKX2.5 gene and the PAX8 promoter in a girl with thyroid dysgenesis. J. Clin. Endocrinol. Metab. 96, E977-E981 (2011)
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, pp. E977-E981
-
-
Hermanns, P.1
Grasberger, H.2
Refetoff, S.3
Pohlenz, J.4
-
142
-
-
84902164495
-
A new mutation in the promoter region of the PAX8 gene causes true congenital hypothyroidism with thyroid hypoplasia in a girl with Down's syndrome
-
Hermanns, P. et al. A new mutation in the promoter region of the PAX8 gene causes true congenital hypothyroidism with thyroid hypoplasia in a girl with Down's syndrome. Thyroid 24, 939-944 (2014)
-
(2014)
Thyroid
, vol.24
, pp. 939-944
-
-
Hermanns, P.1
-
143
-
-
17344374131
-
PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis
-
Macchia, P. E. et al. PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis. Nat. Genet. 19, 83-86 (1998)
-
(1998)
Nat. Genet
, vol.19
, pp. 83-86
-
-
Macchia, P.E.1
-
144
-
-
84867487106
-
Functional characterization of four novel PAX8 mutations causing congenital hypothyroidism: New evidence for haploinsufficiency as a disease mechanism
-
Narumi, S. et al. Functional characterization of four novel PAX8 mutations causing congenital hypothyroidism: new evidence for haploinsufficiency as a disease mechanism. Eur. J. Endocrinol. 167, 625-632 (2012)
-
(2012)
Eur. J. Endocrinol
, vol.167
, pp. 625-632
-
-
Narumi, S.1
-
145
-
-
23044482192
-
Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: Clinical characterization and exclusion of candidate loci
-
Grasberger, H. et al. Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci. J. Clin. Endocrinol. Metab. 90, 4025-4034 (2005)
-
(2005)
J. Clin. Endocrinol. Metab
, vol.90
, pp. 4025-4034
-
-
Grasberger, H.1
-
146
-
-
84884125512
-
A new PAX8 mutation causing congenital hypothyroidism in three generations of a family is associated with abnormalities in the urogenital tract
-
Carvalho, A. et al. A new PAX8 mutation causing congenital hypothyroidism in three generations of a family is associated with abnormalities in the urogenital tract. Thyroid 23, 1074-1078 (2013)
-
(2013)
Thyroid
, vol.23
, pp. 1074-1078
-
-
Carvalho, A.1
-
147
-
-
4544229648
-
Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid
-
Meeus, L. et al. Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. J. Clin. Endocrinol. Metab. 89, 4285-4291 (2004)
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, pp. 4285-4291
-
-
Meeus, L.1
-
148
-
-
27844536962
-
A mouse model demonstrates a multigenic origin of congenital hypothyroidism
-
Amendola, E. et al. A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology 146, 5038-5047 (2005)
-
(2005)
Endocrinology
, vol.146
, pp. 5038-5047
-
-
Amendola, E.1
-
149
-
-
81455140607
-
The microRNA-processing enzyme Dicer is essential for thyroid function
-
Frezzetti, D. et al. The microRNA-processing enzyme Dicer is essential for thyroid function. PLoS ONE 6, e27648 (2011)
-
(2011)
PLoS ONE
, vol.6
, pp. e27648
-
-
Frezzetti, D.1
-
150
-
-
84855391733
-
Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations
-
Rodriguez, W. et al. Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations. PLoS ONE 7, e29929 (2012)
-
(2012)
PLoS ONE
, vol.7
, pp. e29929
-
-
Rodriguez, W.1
-
151
-
-
0036739991
-
Discordance of monozygotic twins for thyroid dysgenesis: Implications for screening and for molecular pathophysiology
-
Perry, R. et al. Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology. J. Clin. Endocrinol. Metab. 87, 4072-4077 (2002)
-
(2002)
J. Clin. Endocrinol. Metab
, vol.87
, pp. 4072-4077
-
-
Perry, R.1
-
152
-
-
84902324944
-
Role for tissue-dependent methylation differences in the expression of FOXE1 in non-tumoral thyroid glands
-
Abu-Khudir, R. et al. Role for tissue-dependent methylation differences in the expression of FOXE1 in non-tumoral thyroid glands. J. Clin. Endocrinol. Metab. 99, E1120-E1129 (2014)
-
(2014)
J. Clin. Endocrinol. Metab
, vol.99
, pp. E1120-E1129
-
-
Abu-Khudir, R.1
-
153
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay, J. et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127, 2893-2917 (2010)
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
-
154
-
-
80053150200
-
Molecular genetics and diagnosis of thyroid cancer
-
Nikiforov, Y. E. & Nikiforova, M. N. Molecular genetics and diagnosis of thyroid cancer. Nat. Rev. Endocrinol. 7, 569-580 (2011)
-
(2011)
Nat. Rev. Endocrinol
, vol.7
, pp. 569-580
-
-
Nikiforov, Y.E.1
Nikiforova, M.N.2
-
155
-
-
3142705737
-
The role of TTF-1 in differentiating primary and metastatic lung adenocarcinomas
-
Moldvay, J. et al. The role of TTF-1 in differentiating primary and metastatic lung adenocarcinomas. Pathol. Oncol. Res. 10, 85-88 (2004)
-
(2004)
Pathol. Oncol. Res
, vol.10
, pp. 85-88
-
-
Moldvay, J.1
-
156
-
-
0037531707
-
Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: A high-throughput tissue microarray and immunohistochemistry study
-
Tan, D. et al. Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: a high-throughput tissue microarray and immunohistochemistry study. Hum. Pathol. 34, 597-604 (2003)
-
(2003)
Hum. Pathol
, vol.34
, pp. 597-604
-
-
Tan, D.1
-
157
-
-
0347419411
-
Thyroid transcription factor-1 (TTF-1) expression in human lung carcinomas: Its prognostic implication and relationship with expressions of p53 and Ki-67 proteins
-
Myong, N. H. Thyroid transcription factor-1 (TTF-1) expression in human lung carcinomas: its prognostic implication and relationship with expressions of p53 and Ki-67 proteins. J. Korean Med. Sci. 18, 494-500 (2003)
-
(2003)
J. Korean Med. Sci
, vol.18
, pp. 494-500
-
-
Myong, N.H.1
-
158
-
-
69349095714
-
Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma
-
Barletta, J. A. et al. Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma. J. Cell. Mol. Med. 13, 1977-1986 (2009)
-
(2009)
J. Cell. Mol. Med
, vol.13
, pp. 1977-1986
-
-
Barletta, J.A.1
-
159
-
-
84878965845
-
NKX2-1/TTF-1: An enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression
-
Yamaguchi, T., Hosono, Y., Yanagisawa, K. & Takahashi, T. NKX2-1/TTF-1: an enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression. Cancer Cell 23, 718-723 (2013)
-
(2013)
Cancer Cell
, vol.23
, pp. 718-723
-
-
Yamaguchi, T.1
Hosono, Y.2
Yanagisawa, K.3
Takahashi, T.4
-
160
-
-
84883651787
-
The complexity of thyroid transcription factor 1 with both pro-and anti-oncogenic activities
-
Mu, D. The complexity of thyroid transcription factor 1 with both pro-and anti-oncogenic activities. J. Biol. Chem. 288, 24992-25000 (2013)
-
(2013)
J. Biol. Chem
, vol.288
, pp. 24992-25000
-
-
Mu, D.1
-
161
-
-
33645771184
-
Immunohistochemical analysis of thyroid-specific transcription factors in thyroid tumors
-
Zhang, P. et al. Immunohistochemical analysis of thyroid-specific transcription factors in thyroid tumors. Pathol. Int. 56, 240-245 (2006)
-
(2006)
Pathol. Int
, vol.56
, pp. 240-245
-
-
Zhang, P.1
-
162
-
-
0034145199
-
Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas
-
Ordonez, N. G. Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas. Adv. Anat. Pathol. 7, 123-127 (2000)
-
(2000)
Adv. Anat. Pathol
, vol.7
, pp. 123-127
-
-
Ordonez, N.G.1
-
163
-
-
0034105756
-
Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomas
-
Katoh, R. et al. Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomas. Hum. Pathol. 31, 386-393 (2000)
-
(2000)
Hum. Pathol
, vol.31
, pp. 386-393
-
-
Katoh, R.1
-
164
-
-
63449092713
-
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
-
Gudmundsson, J. et al. Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat. Genet. 41, 460-464 (2009)
-
(2009)
Nat. Genet
, vol.41
, pp. 460-464
-
-
Gudmundsson, J.1
-
165
-
-
59749093841
-
A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma
-
Ngan, E. S. et al. A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma. J. Natl Cancer Inst. 101, 162-175 (2009)
-
(2009)
J. Natl Cancer Inst
, vol.101
, pp. 162-175
-
-
Ngan, E.S.1
-
166
-
-
79953735093
-
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia
-
Homminga, I. et al. Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell 19, 484-497 (2011)
-
(2011)
Cancer Cell
, vol.19
, pp. 484-497
-
-
Homminga, I.1
-
167
-
-
70349690194
-
The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors
-
Landa, I. et al. The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. PLoS Genet. 5, e1000637 (2009)
-
(2009)
PLoS Genet
, vol.5
, pp. e1000637
-
-
Landa, I.1
-
168
-
-
77955301455
-
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl
-
Takahashi, M. et al. The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. Hum. Mol. Genet. 19, 2516-2523 (2010)
-
(2010)
Hum. Mol. Genet
, vol.19
, pp. 2516-2523
-
-
Takahashi, M.1
-
169
-
-
38649127254
-
Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms
-
Nonaka, D., Tang, Y., Chiriboga, L., Rivera, M. & Ghossein, R. Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms. Mod. Pathol. 21, 192-200 (2008)
-
(2008)
Mod. Pathol
, vol.21
, pp. 192-200
-
-
Nonaka, D.1
Tang, Y.2
Chiriboga, L.3
Rivera, M.4
Ghossein, R.5
-
170
-
-
0035185882
-
Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions
-
Sequeira, M. J. et al. Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions. Thyroid 11, 995-1001 (2001)
-
(2001)
Thyroid
, vol.11
, pp. 995-1001
-
-
Sequeira, M.J.1
-
171
-
-
84881442899
-
Patterns of FOXE1 expression in papillary thyroid carcinoma by immunohistochemistry
-
Bychkov, A. et al. Patterns of FOXE1 expression in papillary thyroid carcinoma by immunohistochemistry. Thyroid 23, 817-828 (2013)
-
(2013)
Thyroid
, vol.23
, pp. 817-828
-
-
Bychkov, A.1
-
172
-
-
0030015888
-
Differential allele loss on chromosome 9q22.3 in human non-melanoma skin cancer
-
Holmberg, E., Rozell, B. L. & Toftgard, R. Differential allele loss on chromosome 9q22.3 in human non-melanoma skin cancer. Br. J. Cancer 74, 246-250 (1996)
-
(1996)
Br. J. Cancer
, vol.74
, pp. 246-250
-
-
Holmberg, E.1
Rozell, B.L.2
Toftgard, R.3
-
173
-
-
77951240348
-
FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma
-
Venza, I. et al. FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma. Br. J. Dermatol. 162, 1093-1097 (2009)
-
(2009)
Br. J. Dermatol
, vol.162
, pp. 1093-1097
-
-
Venza, I.1
-
174
-
-
76949090280
-
Investigation into FOXE1 genetic variations in cutaneous squamous cell carcinoma
-
Venza, I. et al. Investigation into FOXE1 genetic variations in cutaneous squamous cell carcinoma. Br. J. Dermatol. 162, 681-683 (2009)
-
(2009)
Br. J. Dermatol
, vol.162
, pp. 681-683
-
-
Venza, I.1
-
175
-
-
57449111916
-
Genetic and epigenetic alterations of familial pancreatic cancers
-
Brune, K. et al. Genetic and epigenetic alterations of familial pancreatic cancers. Cancer Epidemiol. Biomarkers Prev. 17, 3536-3542 (2008)
-
(2008)
Cancer Epidemiol. Biomarkers Prev
, vol.17
, pp. 3536-3542
-
-
Brune, K.1
-
176
-
-
49249091385
-
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight
-
Weisenberger, D. J. et al. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Res. 36, 4689-4698 (2008)
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4689-4698
-
-
Weisenberger, D.J.1
-
177
-
-
69549116604
-
Expression of PAX8 in normal and neoplastic renal tissues: An immunohistochemical study
-
Tong, G. X. et al. Expression of PAX8 in normal and neoplastic renal tissues: an immunohistochemical study. Mod. Pathol. 22, 1218-1227 (2009)
-
(2009)
Mod. Pathol
, vol.22
, pp. 1218-1227
-
-
Tong, G.X.1
-
178
-
-
77951822119
-
PAX8 reliably distinguishes ovarian serous tumors from malignant mesothelioma
-
Laury, A. R. et al. PAX8 reliably distinguishes ovarian serous tumors from malignant mesothelioma. Am. J. Surg. Pathol. 34, 627-635 (2010)
-
(2010)
Am. J. Surg. Pathol
, vol.34
, pp. 627-635
-
-
Laury, A.R.1
-
179
-
-
80051771821
-
Diagnostic utility of PAX8 and PAX2 immunohistochemistry in the identification of metastatic Mullerian carcinoma in effusions
-
Wiseman, W., Michael, C. W. & Roh, M. H. Diagnostic utility of PAX8 and PAX2 immunohistochemistry in the identification of metastatic Mullerian carcinoma in effusions. Diagn. Cytopathol. 39, 651-656 (2011)
-
(2011)
Diagn. Cytopathol
, vol.39
, pp. 651-656
-
-
Wiseman, W.1
Michael, C.W.2
Roh, M.H.3
-
180
-
-
0034714190
-
PAX8-PPARγ1 fusion oncogene in human thyroid carcinoma [corrected]
-
Kroll, T. G. et al. PAX8-PPARγ1 fusion oncogene in human thyroid carcinoma [corrected]. Science 289, 1357-1360 (2000)
-
(2000)
Science
, vol.289
, pp. 1357-1360
-
-
Kroll, T.G.1
-
181
-
-
2442697906
-
The PAX8/PPARγ fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARγ inhibition
-
Gregory Powell, J. et al. The PAX8/PPARγ fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARγ inhibition. Oncogene 23, 3634-3641 (2004)
-
(2004)
Oncogene
, vol.23
, pp. 3634-3641
-
-
Gregory Powell, J.1
-
182
-
-
55949130900
-
The role of the PAX8/PPARγ fusion oncogene in thyroid cancer
-
Placzkowski, K. A., Reddi, H. V., Grebe, S. K., Eberhardt, N. L. & McIver, B. The role of the PAX8/PPARγ fusion oncogene in thyroid cancer. PPAR Res. 2008, 672829 (2008)
-
(2008)
PPAR Res
, vol.2008
, pp. 672829
-
-
Placzkowski, K.A.1
Reddi, H.V.2
Grebe, S.K.3
Eberhardt, N.L.4
McIver, B.5
-
183
-
-
0036344885
-
Expression of PAX8-PPARγ1 rearrangements in both follicular thyroid carcinomas and adenomas
-
Marques, A. R. et al. Expression of PAX8-PPARγ1 rearrangements in both follicular thyroid carcinomas and adenomas. J. Clin. Endocrinol. Metab. 87, 3947-3952 (2002)
-
(2002)
J. Clin. Endocrinol. Metab
, vol.87
, pp. 3947-3952
-
-
Marques, A.R.1
-
184
-
-
0037238701
-
Detection of the PAX8-PPARγ fusion oncogene in both follicular thyroid carcinomas and adenomas
-
Cheung, L. et al. Detection of the PAX8-PPARγ fusion oncogene in both follicular thyroid carcinomas and adenomas. J. Clin. Endocrinol. Metab. 88, 354-357 (2003)
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 354-357
-
-
Cheung, L.1
-
185
-
-
84884508113
-
An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility
-
Landa, I. et al. An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility. PLoS ONE 8, e74765 (2013)
-
(2013)
PLoS ONE
, vol.8
, pp. e74765
-
-
Landa, I.1
-
186
-
-
0036959993
-
Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors
-
D'Elia, A. V. et al. Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors. J. Clin. Endocrinol. Metab. 87, 1376-1383 (2002)
-
(2002)
J. Clin. Endocrinol. Metab
, vol.87
, pp. 1376-1383
-
-
D'elia, A.V.1
-
187
-
-
47049115637
-
Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia
-
Jankovic, D. et al. Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia. Blood 111, 5672-5682 (2008)
-
(2008)
Blood
, vol.111
, pp. 5672-5682
-
-
Jankovic, D.1
-
188
-
-
33747403822
-
HEX expression and localization in normal mammary gland and breast carcinoma
-
Puppin, C. et al. HEX expression and localization in normal mammary gland and breast carcinoma. BMC Cancer 6, 192 (2006)
-
(2006)
BMC Cancer
, vol.6
, pp. 192
-
-
Puppin, C.1
-
189
-
-
0033988367
-
Recent advances in understanding the molecular basis of primary congenital hypothyroidism
-
Macchia, P. E. Recent advances in understanding the molecular basis of primary congenital hypothyroidism. Mol. Med. Today 6, 36-42 (2000)
-
(2000)
Mol. Med. Today
, vol.6
, pp. 36-42
-
-
Macchia, P.E.1
|