-
1
-
-
33746565431
-
Lineage dependency and lineage- survival oncogenes in human cancer
-
Garraway, L. A., and Sellers, W. R. (2006) Lineage dependency and lineage- survival oncogenes in human cancer. Nat. Rev. Cancer 6, 593-602
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 593-602
-
-
Garraway, L.A.1
Sellers, W.R.2
-
2
-
-
0034145199
-
Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas
-
Ordóñez, N. G. (2000) Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas. Adv. Anat. Pathol. 7, 123-127
-
(2000)
Adv. Anat. Pathol
, vol.7
, pp. 123-127
-
-
Ordóñez, N.G.1
-
3
-
-
1842507147
-
Thyroid transcription factor 1 in pulmonary adenocarcinoma
-
Stenhouse, G., Fyfe, N., King, G., Chapman, A., and Kerr, K. M. (2004) Thyroid transcription factor 1 in pulmonary adenocarcinoma. J. Clin. Pathol. 57, 383-387
-
(2004)
J. Clin. Pathol
, vol.57
, pp. 383-387
-
-
Stenhouse, G.1
Fyfe, N.2
King, G.3
Chapman, A.4
Kerr, K.M.5
-
4
-
-
0028024585
-
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
-
Bohinski, R. J., Di Lauro, R., and Whitsett, J. A. (1994) The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol. Cell. Biol. 14, 5671-5681
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 5671-5681
-
-
Bohinski, R.J.1
Di Lauro, R.2
Whitsett, J.A.3
-
5
-
-
0030057596
-
The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
-
Kimura, S., Hara, Y., Pineau, T., Fernandez-Salguero, P., Fox, C. H., Ward, J. M., and Gonzalez, F. J. (1996) The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10, 60-69
-
(1996)
Genes Dev
, vol.10
, pp. 60-69
-
-
Kimura, S.1
Hara, Y.2
Pineau, T.3
Fernandez-Salguero, P.4
Fox, C.H.5
Ward, J.M.6
Gonzalez, F.J.7
-
6
-
-
0033135419
-
Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos
-
Minoo, P., Su, G., Drum, H., Bringas, P., and Kimura, S. (1999) Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 209, 60-71
-
(1999)
Dev. Biol
, vol.209
, pp. 60-71
-
-
Minoo, P.1
Su, G.2
Drum, H.3
Bringas, P.4
Kimura, S.5
-
7
-
-
36749068356
-
Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer
-
Kendall, J., Liu, Q., Bakleh, A., Krasnitz, A., Nguyen, K. C., Lakshmi, B., Gerald, W. L., Powers, S., and Mu, D. (2007) Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer. Proc. Natl. Acad. Sci. U.S.A. 104, 16663-16668
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 16663-16668
-
-
Kendall, J.1
Liu, Q.2
Bakleh, A.3
Krasnitz, A.4
Nguyen, K.C.5
Lakshmi, B.6
Gerald, W.L.7
Powers, S.8
Mu, D.9
-
8
-
-
44449178497
-
Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer
-
Kwei, K. A., Kim, Y. H., Girard, L., Kao, J., Pacyna-Gengelbach, M., Salari, K., Lee, J., Choi, Y. L., Sato, M., Wang, P., Hernandez-Boussard, T., Gazdar, A. F., Petersen, I., Minna, J. D., and Pollack, J. R. (2008) Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene 27, 3635-3640
-
(2008)
Oncogene
, vol.27
, pp. 3635-3640
-
-
Kwei, K.A.1
Kim, Y.H.2
Girard, L.3
Kao, J.4
Pacyna-Gengelbach, M.5
Salari, K.6
Lee, J.7
Choi, Y.L.8
Sato, M.9
Wang, P.10
Hernandez-Boussard, T.11
Gazdar, A.F.12
Petersen, I.13
Minna, J.D.14
Pollack, J.R.15
-
9
-
-
34447131535
-
Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1
-
Tanaka, H., Yanagisawa, K., Shinjo, K., Taguchi, A., Maeno, K., Tomida, S., Shimada, Y., Osada, H., Kosaka, T., Matsubara, H., Mitsudomi, T., Sekido, Y., Tanimoto, M., Yatabe, Y., and Takahashi, T. (2007) Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1. Cancer Res. 67, 6007-6011
-
(2007)
Cancer Res
, vol.67
, pp. 6007-6011
-
-
Tanaka, H.1
Yanagisawa, K.2
Shinjo, K.3
Taguchi, A.4
Maeno, K.5
Tomida, S.6
Shimada, Y.7
Osada, H.8
Kosaka, T.9
Matsubara, H.10
Mitsudomi, T.11
Sekido, Y.12
Tanimoto, M.13
Yatabe, Y.14
Takahashi, T.15
-
10
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
Weir, B. A., Woo, M. S., Getz, G., Perner, S., Ding, L., Beroukhim, R., Lin, W. M., Province, M. A., Kraja, A., Johnson, L. A., Shah, K., Sato, M., Thomas, R. K., Barletta, J. A., Borecki, I. B., Broderick, S., Chang, A. C., Chiang, D. Y., Chirieac, L. R., Cho, J., Fujii, Y., Gazdar, A. F., Giordano, T., Greulich, H., Hanna, M., Johnson, B. E., Kris, M. G., Lash, A., Lin, L., Lindeman, N., Mardis, E. R., McPherson, J. D., Minna, J. D., Morgan, M. B., Nadel, M., Orringer, M. B., Osborne, J. R., Ozenberger, B., Ramos, A. H., Robinson, J., Roth, J. A., Rusch, V., Sasaki, H., Shepherd, F., Sougnez, C., Spitz, M. R., Tsao, M. S., Twomey, D., Verhaak, R. G., Weinstock, G. M., Wheeler, D. A., Winckler, W., Yoshizawa, A., Yu, S., Zakowski, M. F., Zhang, Q., Beer, D. G., Wistuba, I. I., Watson, M. A., Garraway, L. A., Ladanyi, M., Travis, W. D., Pao, W., Rubin, M. A., Gabriel, S. B., Gibbs, R. A., Varmus, H. E., Wilson, R. K., Lander, E. S., and Meyerson, M. (2007) Characterizing the cancer genome in lung adenocarcinoma. Nature 450, 893-898
-
(2007)
Nature
, vol.450
, pp. 893-898
-
-
Weir, B.A.1
Woo, M.S.2
Getz, G.3
Perner, S.4
Ding, L.5
Beroukhim, R.6
Lin, W.M.7
Province, M.A.8
Kraja, A.9
Johnson, L.A.10
Shah, K.11
Sato, M.12
Thomas, R.K.13
Barletta, J.A.14
Borecki, I.B.15
Broderick, S.16
Chang, A.C.17
Chiang, D.Y.18
Chirieac, L.R.19
Cho, J.20
Fujii, Y.21
Gazdar, A.F.22
Giordano, T.23
Greulich, H.24
Hanna, M.25
Johnson, B.E.26
Kris, M.G.27
Lash, A.28
Lin, L.29
Lindeman, N.30
Mardis, E.R.31
McPherson, J.D.32
Minna, J.D.33
Morgan, M.B.34
Nadel, M.35
Orringer, M.B.36
Osborne, J.R.37
Ozenberger, B.38
Ramos, A.H.39
Robinson, J.40
Roth, J.A.41
Rusch, V.42
Sasaki, H.43
Shepherd, F.44
Sougnez, C.45
Spitz, M.R.46
Tsao, M.S.47
Twomey, D.48
Verhaak, R.G.49
Weinstock, G.M.50
Wheeler, D.A.51
Winckler, W.52
Yoshizawa, A.53
Yu, S.54
Zakowski, M.F.55
Zhang, Q.56
Beer, D.G.57
Wistuba, I.I.58
Watson, M.A.59
Garraway, L.A.60
Ladanyi, M.61
Travis, W.D.62
Pao, W.63
Rubin, M.A.64
Gabriel, S.B.65
Gibbs, R.A.66
Varmus, H.E.67
Wilson, R.K.68
Lander, E.S.69
Meyerson, M.70
more..
-
11
-
-
79955584983
-
Suppression of lung adenocarcinoma progression by Nkx2-1
-
Winslow, M. M., Dayton, T. L., Verhaak, R. G., Kim-Kiselak, C., Snyder, E. L., Feldser, D. M., Hubbard, D. D., DuPage, M. J., Whittaker, C. A., Hoersch, S., Yoon, S., Crowley, D., Bronson, R. T., Chiang, D. Y., Meyerson, M., and Jacks, T. (2011) Suppression of lung adenocarcinoma progression by Nkx2-1. Nature 473, 101-104
-
(2011)
Nature
, vol.473
, pp. 101-104
-
-
Winslow, M.M.1
Dayton, T.L.2
Verhaak, R.G.3
Kim-Kiselak, C.4
Snyder, E.L.5
Feldser, D.M.6
Hubbard, D.D.7
Dupage, M.J.8
Whittaker, C.A.9
Hoersch, S.10
Yoon, S.11
Crowley, D.12
Bronson, R.T.13
Chiang, D.Y.14
Meyerson, M.15
Jacks, T.16
-
12
-
-
84861592850
-
MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits
-
Liu, H., Radisky, D. C., Yang, D., Xu, R., Radisky, E. S., Bissell, M. J., and Bishop, J. M. (2012) MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat. Cell Biol. 14, 567-574
-
(2012)
Nat Cell Biol
, vol.14
, pp. 567-574
-
-
Liu, H.1
Radisky, D.C.2
Yang, D.3
Xu, R.4
Radisky, E.S.5
Bissell, M.J.6
Bishop, J.M.7
-
13
-
-
33645213629
-
Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2
-
Liu, H., Radisky, D. C., Nelson, C. M., Zhang, H., Fata, J. E., Roth, R. A., and Bissell, M. J. (2006) Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. Proc. Natl. Acad. Sci. U.S.A. 103, 4134-4139
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 4134-4139
-
-
Liu, H.1
Radisky, D.C.2
Nelson, C.M.3
Zhang, H.4
Fata, J.E.5
Roth, R.A.6
Bissell, M.J.7
-
14
-
-
77955871461
-
The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor
-
Manfredi, J. J. (2010) The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. Genes Dev. 24, 1580-1589
-
(2010)
Genes Dev
, vol.24
, pp. 1580-1589
-
-
Manfredi, J.J.1
-
15
-
-
34247579714
-
A tumor suppressor and oncogene: The WT1 story
-
Yang, L., Han, Y., Saurez Saiz, F., and Minden, M. D. (2007) A tumor suppressor and oncogene: the WT1 story. Leukemia 21, 868-876
-
(2007)
Leukemia
, vol.21
, pp. 868-876
-
-
Yang, L.1
Han, Y.2
Saurez Saiz, F.3
Minden, M.D.4
-
16
-
-
84878138458
-
REST: An oncogene or a tumor suppressor?
-
Negrini, S., Prada, I., D'Alessandro, R., and Meldolesi, J. (2013) REST: an oncogene or a tumor suppressor Trends Cell Biol. 23, 289-295
-
(2013)
Trends Cell Biol
, vol.23
, pp. 289-295
-
-
Negrini, S.1
Prada, I.2
D'Alessandro, R.3
Meldolesi, J.4
-
17
-
-
0037105775
-
The hepatocyte nuclear factor 3α gene, HNF3α (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas
-
Lin, L., Miller, C. T., Contreras, J. I., Prescott, M. S., Dagenais, S. L., Wu, R., Yee, J., Orringer, M. B., Misek, D. E., Hanash, S. M., Glover, T. W., and Beer, D. G. (2002) The hepatocyte nuclear factor 3α gene, HNF3α (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. Cancer Res. 62, 5273-5279
-
(2002)
Cancer Res
, vol.62
, pp. 5273-5279
-
-
Lin, L.1
Miller, C.T.2
Contreras, J.I.3
Prescott, M.S.4
Dagenais, S.L.5
Wu, R.6
Yee, J.7
Orringer, M.B.8
Misek, D.E.9
Hanash, S.M.10
Glover, T.W.11
Beer, D.G.12
-
18
-
-
33644525896
-
High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH
-
Garnis, C., Lockwood, W. W., Vucic, E., Ge, Y., Girard, L., Minna, J. D., Gazdar, A. F., Lam, S., MacAulay, C., and Lam, W. L. (2006) High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int. J. Cancer 118, 1556-1564
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1556-1564
-
-
Garnis, C.1
Lockwood, W.W.2
Vucic, E.3
Ge, Y.4
Girard, L.5
Minna, J.D.6
Gazdar, A.F.7
Lam, S.8
Macaulay, C.9
Lam, W.L.10
-
19
-
-
0036100810
-
TTF-1 expression in pulmonary adenocarcinomas
-
Yatabe, Y., Mitsudomi, T., and Takahashi, T. (2002) TTF-1 expression in pulmonary adenocarcinomas. Am. J. Surg. Pathol. 26, 767-773
-
(2002)
Am. J. Surg. Pathol
, vol.26
, pp. 767-773
-
-
Yatabe, Y.1
Mitsudomi, T.2
Takahashi, T.3
-
20
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
Beroukhim, R., Getz, G., Nghiemphu, L., Barretina, J., Hsueh, T., Linhart, D., Vivanco, I., Lee, J. C., Huang, J. H., Alexander, S., Du, J., Kau, T., Thomas, R. K., Shah, K., Soto, H., Perner, S., Prensner, J., Debiasi, R. M., Demichelis, F., Hatton, C., Rubin, M. A., Garraway, L. A., Nelson, S. F., Liau, L., Mischel, P. S., Cloughesy, T. F., Meyerson, M., Golub, T. A., Lander, E. S., Mellinghoff, I. K., and Sellers, W. R. (2007) Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc. Natl. Acad. Sci. U.S.A. 104, 20007-20012
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
Linhart, D.6
Vivanco, I.7
Lee, J.C.8
Huang, J.H.9
Alexander, S.10
Du, J.11
Kau, T.12
Thomas, R.K.13
Shah, K.14
Soto, H.15
Perner, S.16
Prensner, J.17
Debiasi, R.M.18
Demichelis, F.19
Hatton, C.20
Rubin, M.A.21
Garraway, L.A.22
Nelson, S.F.23
Liau, L.24
Mischel, P.S.25
Cloughesy, T.F.26
Meyerson, M.27
Golub, T.A.28
Lander, E.S.29
Mellinghoff, I.K.30
Sellers, W.R.31
more..
-
21
-
-
65249131825
-
Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer
-
Hsu, D. S., Acharya, C. R., Balakumaran, B. S., Riedel, R. F., Kim, M. K., Stevenson, M., Tuchman, S., Mukherjee, S., Barry, W., Dressman, H. K., Nevins, J. R., Powers, S., Mu, D., and Potti, A. (2009) Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proc. Natl. Acad. Sci. U.S.A. 106, 5312-5317
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 5312-5317
-
-
Hsu, D.S.1
Acharya, C.R.2
Balakumaran, B.S.3
Riedel, R.F.4
Kim, M.K.5
Stevenson, M.6
Tuchman, S.7
Mukherjee, S.8
Barry, W.9
Dressman, H.K.10
Nevins, J.R.11
Powers, S.12
Mu, D.13
Potti, A.14
-
22
-
-
84870547933
-
KrasG12D and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung
-
Maeda, Y., Tsuchiya, T., Hao, H., Tompkins, D. H., Xu, Y., Mucenski, M. L., Du, L., Keiser, A. R., Fukazawa, T., Naomoto, Y., Nagayasu, T., and Whitsett, J. A. (2012) KrasG12D and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung. J. Clin. Invest. 122, 4388-4400
-
(2012)
J. Clin. Invest
, vol.122
, pp. 4388-4400
-
-
Maeda, Y.1
Tsuchiya, T.2
Hao, H.3
Tompkins, D.H.4
Xu, Y.5
Mucenski, M.L.6
Du, L.7
Keiser, A.R.8
Fukazawa, T.9
Naomoto, Y.10
Nagayasu, T.11
Whitsett, J.A.12
-
23
-
-
33644507072
-
Multiple oncogenic changes (K-RASV12, p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells
-
Sato, M., Vaughan, M. B., Girard, L., Peyton, M., Lee, W., Shames, D. S., Ramirez, R. D., Sunaga, N., Gazdar, A. F., Shay, J. W., and Minna, J. D. (2006) Multiple oncogenic changes (K-RASV12, p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. Cancer Res. 66, 2116-2128
-
(2006)
Cancer Res
, vol.66
, pp. 2116-2128
-
-
Sato, M.1
Vaughan, M.B.2
Girard, L.3
Peyton, M.4
Lee, W.5
Shames, D.S.6
Ramirez, R.D.7
Sunaga, N.8
Gazdar, A.F.9
Shay, J.W.10
Minna, J.D.11
-
24
-
-
0035041598
-
Transcription factors in mouse lung development and function
-
Costa, R. H., Kalinichenko, V. V., and Lim, L. (2001) Transcription factors in mouse lung development and function. Am. J. Physiol. Lung Cell. Mol. Physiol. 280, L823-L8388
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.280
-
-
Costa, R.H.1
Kalinichenko, V.V.2
Lim, L.3
-
25
-
-
33846834049
-
Transcriptional control of lung morphogenesis
-
Maeda, Y., Davé, V., and Whitsett, J. A. (2007) Transcriptional control of lung morphogenesis. Physiol. Rev. 87, 219-244
-
(2007)
Physiol. Rev
, vol.87
, pp. 219-244
-
-
Maeda, Y.1
Davé, V.2
Whitsett, J.A.3
-
26
-
-
0034581320
-
Transcriptional regulation of lung development: Emergence of specificity
-
Minoo, P. (2000) Transcriptional regulation of lung development: emergence of specificity. Respir. Res. 1, 109-115
-
(2000)
Respir. Res
, vol.1
, pp. 109-115
-
-
Minoo, P.1
-
27
-
-
15744373791
-
-
IARC Press, Lyon, Francee
-
Travis, W. D., Brambilla, E., Muller-Hermelink, H. K., Harris, C. C. (2004) Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart, IARC Press, Lyon, Francee
-
(2004)
Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart
-
-
Travis, W.D.1
Brambilla, E.2
Muller-Hermelink, H.K.3
Harris, C.C.4
-
28
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium, Dunham, I., Kundaje, A., Aldred, S. F., Collins, P. J., Davis, C. A., Doyle, F., Epstein, C. B., Frietze, S., Harrow, J., Kaul, R., Khatun, J., Lajoie, B. R., Landt, S. G., Lee, B. K., Pauli, F., Rosenbloom, K. R., Sabo, P., Safi, A., Sanyal, A., Shoresh, N., Simon, J. M., Song, L., Trinklein, N. D., Altshuler, R. C., Birney, E., Brown, J. B., Cheng, C., Djebali, S., Dong, X., Dunham, I., Ernst, J., Furey, T. S., Gerstein, M., Giardine, B., Greven, M., Hardison, R. C., Harris, R. S., Herrero, J., Hoffman, M. M., Iyer, S., Kelllis, M., Khatun, J., Kheradpour, P., Kundaje, A., Lassmann, T., Li, Q., Lin, X., Marinov, G. K., Merkel, A., Mortazavi, A., Parker, S. C., Sisu, C., Snow, C., Steward, C., Tanzer, A., Tapanari, E., Tress, M. L., van Baren, M. J., Walters, N., Washieti, S., Wilming, L., Zadissa, A., Zhengdong, Z., Brent, M., Haussler, D., Kellis, M., Valencia, A., Gerstein, M., Raymond, A., Guigo, R., Harrow, J., Hubbard, T. J., Landt, S. G., Frietze, S., Abyzov, A., Addleman, N., Alexander, R. P., Auerbach, R. K., Balasubramanian, S., Bettinger, K., Bhardwaj, N., Boyle, A. P., Cao, A. R., Cayting, P., Charos, A., Cheng, Y., Cheng, C., Eastman, C., Euskirchen, G., Fleming, J. D., Grubert, F., Habegger, L., Hariharan, M., Harmanci, A., Iyenger, S., Jin, V. X., Karczewski, K. J., Kasowski, M., Lacroute, P., Lam, H., Larnarre-Vincent, N., Leng, J., Lian, J., Lindahl-Allen, M., Min, R., Miotto, B., Monahan, H., Moqtaderi, Z., Mu, X. J., O'Geen, H., Ouyang, Z., Patacsil, D., Pei, B., Raha, D., Ramirez, L., Reed, B., Rozowsky, J., Sboner, A., Shi, M., Sisu, C., Slifer, T., Witt, H., Wu, L., Xu, X., Yan, K. K., Yang, X., Yip, K. Y., Zhang, Z., Struhl, K., Weissman, S. M., Gerstein, M., Farnham, P. J., Snyder, M., Tenebaum, S. A., Penalva, L. O., Doyle, F., Karmakar, S., Landt, S. G., Bhanvadia, R. R., Choudhury, A., Domanus, M., Ma, L., Moran, J., Patacsil, D., Slifer, T., Victorsen, A., Yang, X., Snyder, M., White, K. P., Auer, T., Centarin, L., Eichenlaub, M., Gruhl, F., Heerman, S., Hoeckendorf, B., Inoue, D., Kellner, T., Kirchmaier, S., Mueller, C., Reinhardt, R., Schertel, L., Schneider, S., Sinn, R., Wittbrodt, B., Wittbrodt, J., Weng, Z., Whitfield, T. W., Wang, J., Collins, P. J., Aldred, S. F., Trinklein, N. D., Partridge, E. C., Myers, R. M., Dekker, J., Jain, G., Lajoie, B. R., Sanyal, A., Balasundaram, G., Bates, D. L., Byron, R., Canfield, T. K., Diegel, M. J., Dunn, D., Ebersol, A. K., Ebersol, A. K., Frum, T., Garg, K., Gist, E., Hansen, R. S., Boatman, L., Haugen, E., Humbert, R., Jain, G., Johnson, A. K., Johnson, E. M., Kutyavin, T. M., Lajoie, B. R., Lee, K., Lotakis, D., Maurano, M. T., Neph, S. J., Neri, F. V., Nguyen, E. D., Qu, H., Reynolds, A. P., Roach, V., Rynes, E., Sabo, P., Sanchez, M. E., Sandstrom, R. S., Sanyal, A., Shafer, A. O., Stergachis, A. B., Thomas, S., Thurman, R. E., Vernot, B., Vierstra, J., Vong, S., Wang, H., Weaver, M. A., Yan, Y., Zhang, M., Akey, J. A., Bender, M., Dorschner, M. O., Groudine, M., MacCoss, M. J., Navas, P., Stamatoyannopoulos, G., Kaul, R., Dekker, J., Stamatoyannopoulos, J. A., Dunham, I., Beal, K., Brazma, A., Flicek, P., Herrero, J., Johnson, N., Keefe, D., Lukk, M., Luscombe, N. M., Sobral, D., Vaquerizas, J. M., Wilder, S. P., Batzoglou, S., Sidow, A., Hussami, N., Kyriazopoulou-Panagiotopoulou, S., Libbrecht, M. W., Schaub, M. A., Kundaje, A., Hardison, R. C., Miller, W., Giardine, B., Harris, R. S., Wu, W., Bickel, P. J., Banfai, B., Boley, N. P., Brown, J. B., Huang, H., Li, Q., Li, J. J., Noble, W. S., Bilmes, J. A., Buske, O. J., Hoffman, M. M., Sahu, A. O., Kharchenko, P. V., Park, P. J., Baker, D., Taylor, J., Weng, Z., Iyer, S., Dong, X., Greven, M., Lin, X., Wang, J., Xi, H. S., Zhuang, J., Gerstein, M., Alexander, R. P., Balasubramanian, S., Cheng, C., Harmanci, A., Lochovsky, L., Min, R., Mu, X. J., Rozowsky, J., Yan, K. K., Yip, K. Y., and Birney, E. (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Dunham, I.1
Kundaje, A.2
Aldred, S.F.3
Collins, P.J.4
Davis, C.A.5
Doyle, F.6
Epstein, C.B.7
Frietze, S.8
Harrow, J.9
Kaul, R.10
Khatun, J.11
Lajoie, B.R.12
Landt, S.G.13
Lee, B.K.14
Pauli, F.15
Rosenbloom, K.R.16
Sabo, P.17
Safi, A.18
Sanyal, A.19
Shoresh, N.20
Simon, J.M.21
Song, L.22
Trinklein, N.D.23
Altshuler, R.C.24
Birney, E.25
Brown, J.B.26
Cheng, C.27
Djebali, S.28
Dong, X.29
Dunham, I.30
Ernst, J.31
Furey, T.S.32
Gerstein, M.33
Giardine, B.34
Greven, M.35
Hardison, R.C.36
Harris, R.S.37
Herrero, J.38
Hoffman, M.M.39
Iyer, S.40
Kelllis, M.41
Khatun, J.42
Kheradpour, P.43
Kundaje, A.44
Lassmann, T.45
Li, Q.46
Lin, X.47
Marinov, G.K.48
Merkel, A.49
Mortazavi, A.50
Parker, S.C.51
Reddy, T.E.52
Rozowsky, J.53
Schlesinger, F.54
Thurman, R.E.55
Wang, J.56
Ward, L.D.57
Whitfield, T.W.58
Wilder, S.P.59
Wu, W.60
Xi, H.S.61
Yip, K.Y.62
Zhuang, J.63
Bernstein, B.E.64
Birney, E.65
Dunham, I.66
Green, E.D.67
Gunter, C.68
Snyder, M.69
Pazin, M.J.70
Lowdon, R.F.71
Dillon, L.A.72
Adams, L.B.73
Kelly, C.J.74
Zhang, J.75
Wexler, J.R.76
Green, E.D.77
Good, P.J.78
Feingold, E.A.79
Bernstein, B.E.80
Birney, E.81
Crawford, G.E.82
Dekker, J.83
Elinitski, L.84
Farnham, P.J.85
Gerstein, M.86
Giddings, M.C.87
Gingeras, T.R.88
Green, E.D.89
Guigo, R.90
Hardison, R.C.91
Hubbard, T.J.92
Kellis, M.93
Kent, W.J.94
Lieb, J.D.95
Margulies, E.H.96
Myers, R.M.97
Snyder, M.98
Starnatoyannopoulos, J.A.99
more..
-
29
-
-
80555134650
-
Molecular biology of lung cancer clinical implications
-
Larsen, J. E., and Minna, J. D. (2011) Molecular biology of lung cancer: clinical implications. Clin. Chest Med. 32, 703-740
-
(2011)
Clin Chest Med
, vol.32
, pp. 703-740
-
-
Larsen, J.E.1
Minna, J.D.2
-
30
-
-
84860532031
-
Squamous cell carcinoma of the lung molecular subtypes and therapeutic opportunities
-
Perez-Moreno, P., Brambilla, E., Thomas, R., and Soria, J. C. (2012) Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities. Clin. Cancer Res. 18, 2443-2451
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2443-2451
-
-
Perez-Moreno, P.1
Brambilla, E.2
Thomas, R.3
Soria, J.C.4
-
31
-
-
84857794792
-
P40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma
-
Bishop, J. A., Teruya-Feldstein, J., Westra, W. H., Pelosi, G., Travis, W. D., and Rekhtman, N. (2012) p40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma. Mod. Pathol. 25, 405-415
-
(2012)
Mod. Pathol
, vol.25
, pp. 405-415
-
-
Bishop, J.A.1
Teruya-Feldstein, J.2
Westra, W.H.3
Pelosi, G.4
Travis, W.D.5
Rekhtman, N.6
-
32
-
-
79551563284
-
International association for the study of lung cancer/american thoracic society/ european respiratory society international multidisciplinary classification of lung adenocarcinoma
-
Travis, W. D., Brambilla, E., Noguchi, M., Nicholson, A. G., Geisinger, K. R., Yatabe, Y., Beer, D. G., Powell, C. A., Riely, G. J., Van Schil, P. E., Garg, K., Austin, J. H., Asamura, H., Rusch, V. W., Hirsch, F. R., Scagliotti, G., Mitsudomi, T., Huber, R. M., Ishikawa, Y., Jett, J., Sanchez-Cespedes, M., Sculier, J. P., Takahashi, T., Tsuboi, M., Vansteenkiste, J., Wistuba, I., Yang, P. C., Aberle, D., Brambilla, C., Flieder, D., Franklin, W., Gazdar, A., Gould, M., Hasleton, P., Henderson, D., Johnson, B., Johnson, D., Kerr, K., Kuriyama, K., Lee, J. S., Miller, V. A., Petersen, I., Roggli, V., Rosell, R., Saijo, N., Thunnissen, E., Tsao, M., and Yankelewitz, D. (2011) International association for the study of lung cancer/american thoracic society/ european respiratory society international multidisciplinary classification of lung adenocarcinoma. J. Thorac. Oncol. 6, 244-285
-
(2011)
J. Thorac. Oncol
, vol.6
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
Nicholson, A.G.4
Geisinger, K.R.5
Yatabe, Y.6
Beer, D.G.7
Powell, C.A.8
Riely, G.J.9
Van Schil, P.E.10
Garg, K.11
Austin, J.H.12
Asamura, H.13
Rusch, V.W.14
Hirsch, F.R.15
Scagliotti, G.16
Mitsudomi, T.17
Huber, R.M.18
Ishikawa, Y.19
Jett, J.20
Sanchez-Cespedes, M.21
Sculier, J.P.22
Takahashi, T.23
Tsuboi, M.24
Vansteenkiste, J.25
Wistuba, I.26
Yang, P.C.27
Aberle, D.28
Brambilla, C.29
Flieder, D.30
Franklin, W.31
Gazdar, A.32
Gould, M.33
Hasleton, P.34
Henderson, D.35
Johnson, B.36
Johnson, D.37
Kerr, K.38
Kuriyama, K.39
Lee, J.S.40
Miller, V.A.41
Petersen, I.42
Roggli, V.43
Rosell, R.44
Saijo, N.45
Thunnissen, E.46
Tsao, M.47
Yankelewitz, D.48
more..
-
33
-
-
0029932829
-
TTF-1 gene expression in human lung tumours
-
Fabbro, D., Di Loreto, C., Stamerra, O., Beltrami, C. A., Lonigro, R., and Damante, G. (1996) TTF-1 gene expression in human lung tumours. Eur. J. Cancer 32, 512-517
-
(1996)
Eur. J. Cancer
, vol.32
, pp. 512-517
-
-
Fabbro, D.1
Di Loreto, C.2
Stamerra, O.3
Beltrami, C.A.4
Lonigro, R.5
Damante, G.6
-
34
-
-
77649174473
-
Comparison of thyroid transcription factor-1 expression by 2 monoclonal antibodies in pulmonary and nonpulmonary primary tumors
-
Matoso, A., Singh, K., Jacob, R., Greaves, W. O., Tavares, R., Noble, L., Resnick, M. B., Delellis, R. A., and Wang, L. J. (2010) Comparison of thyroid transcription factor-1 expression by 2 monoclonal antibodies in pulmonary and nonpulmonary primary tumors. Appl. Immunohistochem. Mol. Morphol. 18, 142-149
-
(2010)
Appl. Immunohistochem. Mol. Morphol
, vol.18
, pp. 142-149
-
-
Matoso, A.1
Singh, K.2
Jacob, R.3
Greaves, W.O.4
Tavares, R.5
Noble, L.6
Resnick, M.B.7
Delellis, R.A.8
Wang, L.J.9
-
35
-
-
0032970313
-
Prognostic value of thyroid transcription factor-1 in primary, resected, non-small cell lung carcinoma
-
Puglisi, F., Barbone, F., Damante, G., Bruckbauer, M., Di Lauro, V., Beltrami, C. A., and Di Loreto, C. (1999) Prognostic value of thyroid transcription factor-1 in primary, resected, non-small cell lung carcinoma. Mod. Pathol. 12, 318-324
-
(1999)
Mod. Pathol
, vol.12
, pp. 318-324
-
-
Puglisi, F.1
Barbone, F.2
Damante, G.3
Bruckbauer, M.4
Di Lauro, V.5
Beltrami, C.A.6
Di Loreto, C.7
-
36
-
-
84870448257
-
Thyroid transcription factor-1 is not expressed in squamous cell carcinomas of the lung: An immunohistochemical study with review of the literature
-
Ordóñez, N. G. (2012) Thyroid transcription factor-1 is not expressed in squamous cell carcinomas of the lung: an immunohistochemical study with review of the literature. Appl. Immunohistochem. Mol. Morphol. 20, 525-530
-
(2012)
Appl. Immunohistochem. Mol. Morphol
, vol.20
, pp. 525-530
-
-
Ordóñez, N.G.1
-
37
-
-
70350641014
-
SOX2 is an amplified lineagesurvival oncogene in lung and esophageal squamous cell carcinomas
-
U. R
-
Bass, A. J., Watanabe, H., Mermel, C. H., Yu, S., Perner, S., Verhaak, R. G., Kim, S. Y., Wardwell, L., Tamayo, P., Gat-Viks, I., Ramos, A. H., Woo, M. S., Weir, B. A., Getz, G., Beroukhim, R., O'Kelly, M., Dutt, A., Rozenblatt-Rosen, O., Dziunycz, P., Komisarof, J., Chirieac, L. R., Lafargue, C. J., Scheble, V., Wilbertz, T., Ma, C., Rao, S., Nakagawa, H., Stairs, D. B., Lin, L., Giordano, T. J., Wagner, P., Minna, J. D., Gazdar, A. F., Zhu, C. Q., Brose, M. S., Cecconello, I., Jr., U. R., Marie, S. K., Dahl, O., Shivdasani, R. A., Tsao, M. S., Rubin, M. A., Wong, K. K., Regev, A., Hahn, W. C., Beer, D. G., Rustgi, A. K., and Meyerson, M. (2009) SOX2 is an amplified lineagesurvival oncogene in lung and esophageal squamous cell carcinomas. Nat. Genet. 41, 1238-1242
-
(2009)
Nat. Genet
, vol.41
, pp. 1238-1242
-
-
Bass, A.J.1
Watanabe, H.2
Mermel, C.H.3
Yu, S.4
Perner, S.5
Verhaak, R.G.6
Kim, S.Y.7
Wardwell, L.8
Tamayo, P.9
Gat-Viks, I.10
Ramos, A.H.11
Woo, M.S.12
Weir, B.A.13
Getz, G.14
Beroukhim, R.15
O'Kelly, M.16
Dutt, A.17
Rozenblatt-Rosen, O.18
Dziunycz, P.19
Komisarof, J.20
Chirieac, L.R.21
Lafargue, C.J.22
Scheble, V.23
Wilbertz, T.24
Ma, C.25
Rao, S.26
Nakagawa, H.27
Stairs, D.B.28
Lin, L.29
Giordano, T.J.30
Wagner, P.31
Minna, J.D.32
Gazdar, A.F.33
Zhu, C.Q.34
Brose, M.S.35
Cecconello Jr., I.36
Marie, S.K.37
Dahl, O.38
Shivdasani, R.A.39
Tsao, M.S.40
Rubin, M.A.41
Wong, K.K.42
Regev, A.43
Hahn, W.C.44
Beer, D.G.45
Rustgi, A.K.46
Meyerson, M.47
more..
-
38
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network (2012) Comprehensive genomic characterization of squamous cell lung cancers. Nature 489, 519-525
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
39
-
-
58449090870
-
TTF1 expression in non-small cell lung carcinoma: Association with TTF1 gene amplification and improved survival
-
Perner, S., Wagner, P. L., Soltermann, A., LaFargue, C., Tischler, V., Weir, B. A., Weder, W., Meyerson, M., Giordano, T. J., Moch, H., and Rubin, M. A. (2009) TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival. J. Pathol. 217, 65-72
-
(2009)
J. Pathol
, vol.217
, pp. 65-72
-
-
Perner, S.1
Wagner, P.L.2
Soltermann, A.3
Lafargue, C.4
Tischler, V.5
Weir, B.A.6
Weder, W.7
Meyerson, M.8
Giordano, T.J.9
Moch, H.10
Rubin, M.A.11
-
40
-
-
79954583049
-
Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC implications in lung cancer pathogenesis and prognosis
-
Tang, X., Kadara, H., Behrens, C., Liu, D. D., Xiao, Y., Rice, D., Gazdar, A. F., Fujimoto, J., Moran, C., Varella-Garcia, M., Lee, J. J., Hong, W. K., and Wistuba, I. I. (2011) Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis. Clin. Cancer Res. 17, 2434-2443
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 2434-2443
-
-
Tang, X.1
Kadara, H.2
Behrens, C.3
Liu, D.D.4
Xiao, Y.5
Rice, D.6
Gazdar, A.F.7
Fujimoto, J.8
Moran, C.9
Varella-Garcia, M.10
Lee, J.J.11
Hong, W.K.12
Wistuba, I.I.13
-
41
-
-
69349095714
-
Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma
-
Barletta, J. A., Perner, S., Iafrate, A. J., Yeap, B. Y., Weir, B. A., Johnson, L. A., Johnson, B. E., Meyerson, M., Rubin, M. A., Travis, W. D., Loda, M., and Chirieac, L. R. (2009) Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma. J. Cell. Mol. Med. 13, 1977-1986
-
(2009)
J. Cell. Mol. Med
, vol.13
, pp. 1977-1986
-
-
Barletta, J.A.1
Perner, S.2
Iafrate, A.J.3
Yeap, B.Y.4
Weir, B.A.5
Johnson, L.A.6
Johnson, B.E.7
Meyerson, M.8
Rubin, M.A.9
Travis, W.D.10
Loda, M.11
Chirieac, L.R.12
-
42
-
-
84875404794
-
The UCSC Genome Browser database: Extensions and updates 2013
-
Meyer, L. R., Zweig, A. S., Hinrichs, A. S., Karolchik, D., Kuhn, R. M., Wong, M., Sloan, C. A., Rosenbloom, K. R., Roe, G., Rhead, B., Raney, B. J., Pohl, A., Malladi, V. S., Li, C. H., Lee, B. T., Learned, K., Kirkup, V., Hsu, F., Heitner, S., Harte, R. A., Haeussler, M., Guruvadoo, L., Goldman, M., Giardine, B. M., Fujita, P. A., Dreszer, T. R., Diekhans, M., Cline, M. S., Clawson, H., Barber, G. P., Haussler, D., and Kent, W. J. (2013) The UCSC Genome Browser database: extensions and updates 2013. Nucleic Acids Res. 41, D64-D699
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Meyer, L.R.1
Zweig, A.S.2
Hinrichs, A.S.3
Karolchik, D.4
Kuhn, R.M.5
Wong, M.6
Sloan, C.A.7
Rosenbloom, K.R.8
Roe, G.9
Rhead, B.10
Raney, B.J.11
Pohl, A.12
Malladi, V.S.13
Li, C.H.14
Lee, B.T.15
Learned, K.16
Kirkup, V.17
Hsu, F.18
Heitner, S.19
Harte, R.A.20
Haeussler, M.21
Guruvadoo, L.22
Goldman, M.23
Giardine, B.M.24
Fujita, P.A.25
Dreszer, T.R.26
Diekhans, M.27
Cline, M.S.28
Clawson, H.29
Barber, G.P.30
Haussler, D.31
Kent, W.J.32
more..
-
43
-
-
84874634893
-
A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells
-
Fan, M., Li, X., Jiang, W., Huang, Y., Li, J., and Wang, Z. (2013) A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells. Exp. Ther. Med. 5, 1143-1146
-
(2013)
Exp. Ther. Med
, vol.5
, pp. 1143-1146
-
-
Fan, M.1
Li, X.2
Jiang, W.3
Huang, Y.4
Li, J.5
Wang, Z.6
-
44
-
-
82155186923
-
The emergence of lncRNAs in cancer biology
-
Prensner, J. R., and Chinnaiyan, A. M. (2011) The emergence of lncRNAs in cancer biology. Cancer Discov. 1, 391-407
-
(2011)
Cancer Discov
, vol.1
, pp. 391-407
-
-
Prensner, J.R.1
Chinnaiyan, A.M.2
-
45
-
-
84867900638
-
Long non-coding RNAs and cancer: A new frontier of translational research?
-
Spizzo, R., Almeida, M. I., Colombatti, A., and Calin, G. A. (2012) Long non-coding RNAs and cancer: a new frontier of translational research Oncogene 31, 4577-4587
-
(2012)
Oncogene
, vol.31
, pp. 4577-4587
-
-
Spizzo, R.1
Almeida, M.I.2
Colombatti, A.3
Calin, G.A.4
-
46
-
-
84859444521
-
Opposite roles of FOXA1 and NKX2-1 in lung cancer progression
-
Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K., and Wikman, H. (2012) Opposite roles of FOXA1 and NKX2-1 in lung cancer progression. Genes Chromosomes Cancer 51, 618-629
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 618-629
-
-
Deutsch, L.1
Wrage, M.2
Koops, S.3
Glatzel, M.4
Uzunoglu, F.G.5
Kutup, A.6
Hinsch, A.7
Sauter, G.8
Izbicki, J.R.9
Pantel, K.10
Wikman, H.11
-
47
-
-
79951847988
-
Both gene amplification and allelic loss occur at 14q13.3 in lung cancer
-
Harris, T., Pan, Q., Sironi, J., Lutz, D., Tian, J., Sapkar, J., Perez-Soler, R., Keller, S., and Locker, J. (2011) Both gene amplification and allelic loss occur at 14q13.3 in lung cancer. Clin. Cancer Res. 17, 690-699
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 690-699
-
-
Harris, T.1
Pan, Q.2
Sironi, J.3
Lutz, D.4
Tian, J.5
Sapkar, J.6
Perez-Soler, R.7
Keller, S.8
Locker, J.9
-
48
-
-
33751271722
-
Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia
-
Tian, J., Mahmood, R., Hnasko, R., and Locker, J. (2006) Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 66, 10399-10407
-
(2006)
Cancer Res
, vol.66
, pp. 10399-10407
-
-
Tian, J.1
Mahmood, R.2
Hnasko, R.3
Locker, J.4
-
49
-
-
84863384604
-
NKX2-1/TITF1/TTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
-
Yamaguchi, T., Yanagisawa, K., Sugiyama, R., Hosono, Y., Shimada, Y., Arima, C., Kato, S., Tomida, S., Suzuki, M., Osada, H., and Takahashi, T. (2012) NKX2-1/TITF1/TTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma. Cancer Cell 21, 348-361
-
(2012)
Cancer Cell
, vol.21
, pp. 348-361
-
-
Yamaguchi, T.1
Yanagisawa, K.2
Sugiyama, R.3
Hosono, Y.4
Shimada, Y.5
Arima, C.6
Kato, S.7
Tomida, S.8
Suzuki, M.9
Osada, H.10
Takahashi, T.11
-
50
-
-
84874788481
-
Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
-
Watanabe, H., Francis, J. M., Woo, M. S., Etemad, B., Lin, W., Fries, D. F., Peng, S., Snyder, E. L., Tata, P. R., Izzo, F., Schinzel, A. C., Cho, J., Hammerman, P. S., Verhaak, R. G., Hahn, W. C., Rajagopal, J., Jacks, T., and Meyerson, M. (2013) Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target. Genes Dev. 27, 197-210
-
(2013)
Genes Dev
, vol.27
, pp. 197-210
-
-
Watanabe, H.1
Francis, J.M.2
Woo, M.S.3
Etemad, B.4
Lin, W.5
Fries, D.F.6
Peng, S.7
Snyder, E.L.8
Tata, P.R.9
Izzo, F.10
Schinzel, A.C.11
Cho, J.12
Hammerman, P.S.13
Verhaak, R.G.14
Hahn, W.C.15
Rajagopal, J.16
Jacks, T.17
Meyerson, M.18
-
51
-
-
0024039802
-
Acluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor δ chain gene
-
Boehm, T., Buluwela, L., Williams, D., White, L., and Rabbitts, T. H. (1988) Acluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor δ chain gene. EMBO J. 7, 2011-2017
-
(1988)
EMBO J
, vol.7
, pp. 2011-2017
-
-
Boehm, T.1
Buluwela, L.2
Williams, D.3
White, L.4
Rabbitts, T.H.5
-
52
-
-
0024564420
-
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein
-
McGuire, E. A., Hockett, R. D., Pollock, K. M., Bartholdi, M. F., O'Brien, S. J., and Korsmeyer, S. J. (1989) The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. Mol. Cell. Biol. 9, 2124-2132
-
(1989)
Mol. Cell. Biol
, vol.9
, pp. 2124-2132
-
-
McGuire, E.A.1
Hockett, R.D.2
Pollock, K.M.3
Bartholdi, M.F.4
O'Brien, S.J.5
Korsmeyer, S.J.6
-
53
-
-
79953735093
-
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia
-
Homminga, I., Pieters, R., Langerak, A. W., de Rooi, J. J., Stubbs, A., Verstegen, M., Vuerhard, M., Buijs-Gladdines, J., Kooi, C., Klous, P., van Vlierberghe, P., Ferrando, A. A., Cayuela, J. M., Verhaaf, B., Beverloo, H. B., Horstmann, M., de Haas, V., Wiekmeijer, A. S., Pike-Overzet, K., Staal, F. J., de Laat, W., Soulier, J., Sigaux, F., and Meijerink, J. P. (2011) Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell 19, 484-497
-
(2011)
Cancer Cell
, vol.19
, pp. 484-497
-
-
Homminga, I.1
Pieters, R.2
Langerak, A.W.3
De Rooi, J.J.4
Stubbs, A.5
Verstegen, M.6
Vuerhard, M.7
Buijs-Gladdines, J.8
Kooi, C.9
Klous, P.10
Van Vlierberghe, P.11
Ferrando, A.A.12
Cayuela, J.M.13
Verhaaf, B.14
Beverloo, H.B.15
Horstmann, M.16
De Haas, V.17
Wiekmeijer, A.S.18
Pike-Overzet, K.19
Staal, F.J.20
De Laat, W.21
Soulier, J.22
Sigaux, F.23
Meijerink, J.P.24
more..
-
54
-
-
84859811127
-
TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression
-
Dadi, S., Le Noir, S., Payet-Bornet, D., Lhermitte, L., Zacarias-Cabeza, J., Bergeron, J., Villarèse, P., Vachez, E., Dik, W. A., Millien, C., Radford, I., Verhoeyen, E., Cosset, F. L., Petit, A., Ifrah, N., Dombret, H., Hermine, O., Spicuglia, S., Langerak, A. W., Macintyre, E. A., Nadel, B., Ferrier, P., and Asnafi, V. (2012) TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression. Cancer Cell 21, 563-576
-
(2012)
Cancer Cell
, vol.21
, pp. 563-576
-
-
Dadi, S.1
Le Noir, S.2
Payet-Bornet, D.3
Lhermitte, L.4
Zacarias-Cabeza, J.5
Bergeron, J.6
Villarèse, P.7
Vachez, E.8
Dik, W.A.9
Millien, C.10
Radford, I.11
Verhoeyen, E.12
Cosset, F.L.13
Petit, A.14
Ifrah, N.15
Dombret, H.16
Hermine, O.17
Spicuglia, S.18
Langerak, A.W.19
Macintyre, E.A.20
Nadel, B.21
Ferrier, P.22
Asnafi, V.23
more..
-
55
-
-
84876892163
-
Ectopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications
-
Nagel, S., Ehrentraut, S., Tomasch, J., Quentmeier, H., Meyer, C., Kaufmann, M., Drexler, H. G., and Macleod, R. A. (2013) Ectopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications. PLoS ONE 8, e614477
-
(2013)
PLoS ONE
, vol.8
-
-
Nagel, S.1
Ehrentraut, S.2
Tomasch, J.3
Quentmeier, H.4
Meyer, C.5
Kaufmann, M.6
Drexler, H.G.7
Macleod, R.A.8
-
56
-
-
80052581514
-
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models
-
Taguchi, A., Politi, K., Pitteri, S. J., Lockwood, W. W., Faça, V. M., Kelly-Spratt, K., Wong, C. H., Zhang, Q., Chin, A., Park, K. S., Goodman, G., Gazdar, A. F., Sage, J., Dinulescu, D. M., Kucherlapati, R., Depinho, R. A., Kemp, C. J., Varmus, H. E., and Hanash, S. M. (2011) Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell 20, 289-299
-
(2011)
Cancer Cell
, vol.20
, pp. 289-299
-
-
Taguchi, A.1
Politi, K.2
Pitteri, S.J.3
Lockwood, W.W.4
Faça, V.M.5
Kelly-Spratt, K.6
Wong, C.H.7
Zhang, Q.8
Chin, A.9
Park, K.S.10
Goodman, G.11
Gazdar, A.F.12
Sage, J.13
Dinulescu, D.M.14
Kucherlapati, R.15
Depinho, R.A.16
Kemp, C.J.17
Varmus, H.E.18
Hanash, S.M.19
-
57
-
-
59749093841
-
A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma
-
Ngan, E. S. W., Lang, B. H. H., Liu, T., Shum, C. K. Y., So, M.-T., Lau, D. K. C., Leon, T. Y. Y., Cherny, S. S., Tsai, S. Y., Lo, C.-Y., Khoo, U.-S., Tam, P. K. H., and Garcia-Barcelo, M.-M. (2009) A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma. J. Natl. Cancer Inst. 101, 162-175
-
(2009)
J. Natl. Cancer Inst
, vol.101
, pp. 162-175
-
-
Ngan, E.S.W.1
Lang, B.H.H.2
Liu, T.3
Shum, C.K.Y.4
So, M.-T.5
Lau, D.K.C.6
Leon, T.Y.Y.7
Cherny, S.S.8
Tsai, S.Y.9
Lo, C.-Y.10
Khoo, U.-S.11
Tam, P.K.H.12
Garcia-Barcelo, M.-M.13
-
58
-
-
84868374724
-
Generation of functional thyroid from embryonic stem cells
-
Antonica, F., Kasprzyk, D. F., Opitz, R., Iacovino, M., Liao, X. H., Dumitrescu, A. M., Refetoff, S., Peremans, K., Manto, M., Kyba, M., and Costagliola, S. (2012) Generation of functional thyroid from embryonic stem cells. Nature 491, 66-71
-
(2012)
Nature
, vol.491
, pp. 66-71
-
-
Antonica, F.1
Kasprzyk, D.F.2
Opitz, R.3
Iacovino, M.4
Liao, X.H.5
Dumitrescu, A.M.6
Refetoff, S.7
Peremans, K.8
Manto, M.9
Kyba, M.10
Costagliola, S.11
-
59
-
-
84871182766
-
Thyroid-specific transcription factors and their roles in thyroid cancer
-
Kimura, S. (2011) Thyroid-specific transcription factors and their roles in thyroid cancer. J. Thyroid Res. 2011, 7102133
-
(2011)
J. Thyroid Res
, vol.2011
, pp. 7102133
-
-
Kimura, S.1
-
60
-
-
33746607692
-
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid
-
Kusakabe, T., Kawaguchi, A., Hoshi, N., Kawaguchi, R., Hoshi, S., and Kimura, S. (2006) Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Mol. Endocrinol. 20, 1796-1809
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 1796-1809
-
-
Kusakabe, T.1
Kawaguchi, A.2
Hoshi, N.3
Kawaguchi, R.4
Hoshi, S.5
Kimura, S.6
-
61
-
-
63449092713
-
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
-
Gudmundsson, J., Sulem, P., Gudbjartsson, D. F., Jonasson, J. G., Sigurdsson, A., Bergthorsson, J. T., He, H., Blondal, T., Geller, F., Jakobsdottir, M., Magnusdottir, D. N., Matthiasdottir, S., Stacey, S. N., Skarphedinsson, O. B., Helgadottir, H., Li, W., Nagy, R., Aguillo, E., Faure, E., Prats, E., Saez, B., Martinez, M., Eyjolfsson, G. I., Bjornsdottir, U. S., Holm, H., Kristjansson, K., Frigge, M. L., Kristvinsson, H., Gulcher, J. R., Jonsson, T., Rafnar, T., Hjartarsson, H., Mayordomo, J. I., de la Chapelle, A., Hrafnkelsson, J., Thorsteinsdottir, U., Kong, A., and Stefansson, K. (2009) Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat. Genet. 41, 460-464
-
(2009)
Nat. Genet
, vol.41
, pp. 460-464
-
-
Gudmundsson, J.1
Sulem, P.2
Gudbjartsson, D.F.3
Jonasson, J.G.4
Sigurdsson, A.5
Bergthorsson, J.T.6
He, H.7
Blondal, T.8
Geller, F.9
Jakobsdottir, M.10
Magnusdottir, D.N.11
Matthiasdottir, S.12
Stacey, S.N.13
Skarphedinsson, O.B.14
Helgadottir, H.15
Li, W.16
Nagy, R.17
Aguillo, E.18
Faure, E.19
Prats, E.20
Saez, B.21
Martinez, M.22
Eyjolfsson, G.I.23
Bjornsdottir, U.S.24
Holm, H.25
Kristjansson, K.26
Frigge, M.L.27
Kristvinsson, H.28
Gulcher, J.R.29
Jonsson, T.30
Rafnar, T.31
Hjartarsson, H.32
Mayordomo, J.I.33
De La Chapelle, A.34
Hrafnkelsson, J.35
Thorsteinsdottir, U.36
Kong, A.37
Stefansson, K.38
more..
-
62
-
-
4043076215
-
Nkx2.1 transcription factor in lung cells and a transforming growth factor-β1 heterozygous mouse model of lung carcinogenesis
-
Kang, Y., Hebron, H., Ozbun, L., Mariano, J., Minoo, P., and Jakowlew, S. B. (2004) Nkx2.1 transcription factor in lung cells and a transforming growth factor-β1 heterozygous mouse model of lung carcinogenesis. Mol. Carcinog. 40, 212-231
-
(2004)
Mol. Carcinog
, vol.40
, pp. 212-231
-
-
Kang, Y.1
Hebron, H.2
Ozbun, L.3
Mariano, J.4
Minoo, P.5
Jakowlew, S.B.6
-
63
-
-
70249105786
-
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine- induced thyroid adenoma in mice
-
Hoshi, S., Hoshi, N., Okamoto, M., Paiz, J., Kusakabe, T., Ward, J. M., and Kimura, S. (2009) Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine- induced thyroid adenoma in mice. Carcinogenesis 30, 1614-1619
-
(2009)
Carcinogenesis
, vol.30
, pp. 1614-1619
-
-
Hoshi, S.1
Hoshi, N.2
Okamoto, M.3
Paiz, J.4
Kusakabe, T.5
Ward, J.M.6
Kimura, S.7
-
64
-
-
84876835924
-
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma
-
Snyder, E. L., Watanabe, H., Magendantz, M., Hoersch, S., Chen, T. A., Wang, D. G., Crowley, D., Whittaker, C. A., Meyerson, M., Kimura, S., and Jacks, T. (2013) Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Mol. Cell 50, 185-199
-
(2013)
Mol. Cell
, vol.50
, pp. 185-199
-
-
Snyder, E.L.1
Watanabe, H.2
Magendantz, M.3
Hoersch, S.4
Chen, T.A.5
Wang, D.G.6
Crowley, D.7
Whittaker, C.A.8
Meyerson, M.9
Kimura, S.10
Jacks, T.11
-
65
-
-
11244287542
-
Dose-dependent inhibition of thyroid differentiation by RAS oncogenes
-
De Vita, G., Bauer, L., da Costa, V. M., De Felice, M., Baratta, M. G., De Menna, M., and Di Lauro, R. (2005) Dose-dependent inhibition of thyroid differentiation by RAS oncogenes. Mol. Endocrinol. 19, 76-89
-
(2005)
Mol. Endocrinol
, vol.19
, pp. 76-89
-
-
De Vita, G.1
Bauer, L.2
Da Costa, V.M.3
De Felice, M.4
Baratta, M.G.5
De Menna, M.6
Di Lauro, R.7
-
66
-
-
0034079564
-
Multiple Ras downstream pathways mediate functional repression of the homeobox gene product TTF-1
-
Missero, C., Pirro, M. T., and Di Lauro, R. (2000) Multiple Ras downstream pathways mediate functional repression of the homeobox gene product TTF-1. Mol. Cell. Biol. 20, 2783-2793
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2783-2793
-
-
Missero, C.1
Pirro, M.T.2
Di Lauro, R.3
-
67
-
-
84857189404
-
MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis
-
Hosono, Y., Yamaguchi, T., Mizutani, E., Yanagisawa, K., Arima, C., Tomida, S., Shimada, Y., Hiraoka, M., Kato, S., Yokoi, K., Suzuki, M., and Takahashi, T. (2012) MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis. EMBO J. 31, 481-493
-
(2012)
EMBO J
, vol.31
, pp. 481-493
-
-
Hosono, Y.1
Yamaguchi, T.2
Mizutani, E.3
Yanagisawa, K.4
Arima, C.5
Tomida, S.6
Shimada, Y.7
Hiraoka, M.8
Kato, S.9
Yokoi, K.10
Suzuki, M.11
Takahashi, T.12
-
68
-
-
66149094710
-
Thyroid transcription factor-1 inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells
-
Saito, R. A., Watabe, T., Horiguchi, K., Kohyama, T., Saitoh, M., Nagase, T., and Miyazono, K. (2009) Thyroid transcription factor-1 inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells. Cancer Res. 69, 2783-2791
-
(2009)
Cancer Res
, vol.69
, pp. 2783-2791
-
-
Saito, R.A.1
Watabe, T.2
Horiguchi, K.3
Kohyama, T.4
Saitoh, M.5
Nagase, T.6
Miyazono, K.7
-
69
-
-
0037064066
-
Transforming growth factor-β inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors
-
Li, C., Zhu, N. L., Tan, R. C., Ballard, P. L., Derynck, R., and Minoo, P. (2002) Transforming growth factor-β inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors. J. Biol. Chem. 277, 38399-38408
-
(2002)
J. Biol. Chem
, vol.277
, pp. 38399-38408
-
-
Li, C.1
Zhu, N.L.2
Tan, R.C.3
Ballard, P.L.4
Derynck, R.5
Minoo, P.6
-
70
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
-
Ocaña, O. H., Córcoles, R., Fabra, A., Moreno-Bueno, G., Acloque, H., Vega, S., Barrallo-Gimeno, A., Cano, A., and Nieto, M. A. (2012) Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22, 709-724
-
(2012)
Cancer Cell
, vol.22
, pp. 709-724
-
-
Ocaña, O.H.1
Córcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
Barrallo-Gimeno, A.7
Cano, A.8
Nieto, M.A.9
-
71
-
-
84870845421
-
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
-
Tsai, J. H., Donaher, J. L., Murphy, D. A., Chau, S., and Yang, J. (2012) Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22, 725-736
-
(2012)
Cancer Cell
, vol.22
, pp. 725-736
-
-
Tsai, J.H.1
Donaher, J.L.2
Murphy, D.A.3
Chau, S.4
Yang, J.5
-
72
-
-
84865262164
-
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1)
-
Runkle, E. A., Rice, S. J., Qi, J., Masser, D., Antonetti, D. A., Winslow, M. M., and Mu, D. (2012) Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J. Biol. Chem. 287, 28790-28801
-
(2012)
J. Biol. Chem
, vol.287
, pp. 28790-28801
-
-
Runkle, E.A.1
Rice, S.J.2
Qi, J.3
Masser, D.4
Antonetti, D.A.5
Winslow, M.M.6
Mu, D.7
-
73
-
-
0034787457
-
Claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lungand stomach-specific isoforms through alternative splicing
-
Niimi, T., Nagashima, K., Ward, J. M., Minoo, P., Zimonjic, D. B., Popescu, N. C., and Kimura, S. (2001) claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lungand stomach-specific isoforms through alternative splicing. Mol. Cell. Biol. 21, 7380-7390
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 7380-7390
-
-
Niimi, T.1
Nagashima, K.2
Ward, J.M.3
Minoo, P.4
Zimonjic, D.B.5
Popescu, N.C.6
Kimura, S.7
-
74
-
-
84880044601
-
Tight junction proteins: From barrier to tumorigenesis
-
Runkle, E. A., and Mu, D. (2013) Tight junction proteins: from barrier to tumorigenesis. Cancer Lett. 337, 41-48
-
(2013)
Cancer Lett
, vol.337
, pp. 41-48
-
-
Runkle, E.A.1
Mu, D.2
-
75
-
-
66349096981
-
MicroRNA-127 modulates fetal lung development
-
Bhaskaran, M., Wang, Y., Zhang, H., Weng, T., Baviskar, P., Guo, Y., Gou, D., and Liu, L. (2009) MicroRNA-127 modulates fetal lung development. Physiol. Genomics 37, 268-278
-
(2009)
Physiol. Genomics
, vol.37
, pp. 268-278
-
-
Bhaskaran, M.1
Wang, Y.2
Zhang, H.3
Weng, T.4
Baviskar, P.5
Guo, Y.6
Gou, D.7
Liu, L.8
-
76
-
-
78649846540
-
MicroRNA- 449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia
-
Lizé, M., Herr, C., Klimke, A., Bals, R., and Dobbelstein, M. (2010) MicroRNA- 449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia. Cell Cycle 9, 4579-4583
-
(2010)
Cell Cycle
, vol.9
, pp. 4579-4583
-
-
Lizé, M.1
Herr, C.2
Klimke, A.3
Bals, R.4
Dobbelstein, M.5
-
77
-
-
84863429647
-
MicroRNAs and lung cancers: From pathogenesis to clinical implications
-
Qi, J., and Mu, D. (2012) MicroRNAs and lung cancers: from pathogenesis to clinical implications. Front Med. 6, 134-155
-
(2012)
Front Med
, vol.6
, pp. 134-155
-
-
Qi, J.1
Mu, D.2
-
78
-
-
79959923298
-
MicroRNAs and lung cancer: From markers to targets
-
Sozzi, G., Pastorino, U., and Croce, C. M. (2011) MicroRNAs and lung cancer: from markers to targets. Cell Cycle 10, 2045-2046
-
(2011)
Cell Cycle
, vol.10
, pp. 2045-2046
-
-
Sozzi, G.1
Pastorino, U.2
Croce, C.M.3
-
79
-
-
37349096992
-
MicroRNA signature predicts survival and relapse in lung cancer
-
Yu, S. L., Chen, H. Y., Chang, G. C., Chen, C. Y., Chen, H. W., Singh, S., Cheng, C. L., Yu, C. J., Lee, Y. C., Chen, H. S., Su, T. J., Chiang, C. C., Li, H. N., Hong, Q. S., Su, H. Y., Chen, C. C., Chen, W. J., Liu, C. C., Chan, W. K., Chen, W. J., Li, K. C., Chen, J. J., and Yang, P. C. (2008) MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 13, 48-57
-
(2008)
Cancer Cell
, vol.13
, pp. 48-57
-
-
Yu, S.L.1
Chen, H.Y.2
Chang, G.C.3
Chen, C.Y.4
Chen, H.W.5
Singh, S.6
Cheng, C.L.7
Yu, C.J.8
Lee, Y.C.9
Chen, H.S.10
Su, T.J.11
Chiang, C.C.12
Li, H.N.13
Hong, Q.S.14
Su, H.Y.15
Chen, C.C.16
Chen, W.J.17
Liu, C.C.18
Chan, W.K.19
Chen, W.J.20
Li, K.C.21
Chen, J.J.22
Yang, P.C.23
more..
-
80
-
-
77956270748
-
MicroRNA networks in mouse lung organogenesis
-
Dong, J., Jiang, G., Asmann, Y. W., Tomaszek, S., Jen, J., Kislinger, T., and Wigle, D. A. (2010) MicroRNA networks in mouse lung organogenesis. PLoS ONE 5, e108544
-
(2010)
PLoS ONE
, vol.5
-
-
Dong, J.1
Jiang, G.2
Asmann, Y.W.3
Tomaszek, S.4
Jen, J.5
Kislinger, T.6
Wigle, D.A.7
-
81
-
-
34250805982
-
MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
-
Grimson, A., Farh, K. K., Johnston, W. K., Garrett-Engele, P., Lim, L. P., and Bartel, D. P. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 27, 91-105
-
(2007)
Mol. Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
82
-
-
84855685246
-
MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1
-
Qi, J., Rice, S. J., Salzberg, A. C., Runkle, E. A., Liao, J., Zander, D. S., and Mu, D. (2012) MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. Cell Cycle 11, 177-186
-
(2012)
Cell Cycle
, vol.11
, pp. 177-186
-
-
Qi, J.1
Rice, S.J.2
Salzberg, A.C.3
Runkle, E.A.4
Liao, J.5
Zander, D.S.6
Mu, D.7
-
83
-
-
84878236937
-
MicroRNA-365 regulates NKX2-1, a key mediator of lung cancer
-
Kang, S. M., Lee, H. J., and Cho, J. Y. (2013) MicroRNA-365 regulates NKX2-1, a key mediator of lung cancer. Cancer Lett. 335, 487-494
-
(2013)
Cancer Lett
, vol.335
, pp. 487-494
-
-
Kang, S.M.1
Lee, H.J.2
Cho, J.Y.3
-
84
-
-
84878760251
-
MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1)
-
Rice, S. J., Lai, S. C., Wood, L. W., Helsley, K. R., Runkle, E. A., Winslow, M. M., and Mu, D. (2013) MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1). J. Biol. Chem. 288, 16348-16360
-
(2013)
J. Biol. Chem
, vol.288
, pp. 16348-16360
-
-
Rice, S.J.1
Lai, S.C.2
Wood, L.W.3
Helsley, K.R.4
Runkle, E.A.5
Winslow, M.M.6
Mu, D.7
-
85
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown, M. S., and Goldstein, J. L. (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
86
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton, J. D., Goldstein, J. L., and Brown, M. S. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109, 1125-1131
-
(2002)
J. Clin. Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
87
-
-
77958553499
-
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation
-
Gerin, I., Clerbaux, L. A., Haumont, O., Lanthier, N., Das, A. K., Burant, C. F., Leclercq, I. A., MacDougald, O. A., and Bommer, G. T. (2010) Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J. Biol. Chem. 285, 33652-33661
-
(2010)
J. Biol. Chem
, vol.285
, pp. 33652-33661
-
-
Gerin, I.1
Clerbaux, L.A.2
Haumont, O.3
Lanthier, N.4
Das, A.K.5
Burant, C.F.6
Leclercq, I.A.7
Macdougald, O.A.8
Bommer, G.T.9
-
88
-
-
77955456415
-
MiR-33 links SREBP-2 induction to repression of sterol transporters
-
Marquart, T. J., Allen, R. M., Ory, D. S., and Baldán, A. (2010) miR-33 links SREBP-2 induction to repression of sterol transporters. Proc. Natl. Acad. Sci. U.S.A. 107, 12228-12232
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 12228-12232
-
-
Marquart, T.J.1
Allen, R.M.2
Ory, D.S.3
Baldán, A.4
-
89
-
-
77953780835
-
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
-
Najafi-Shoushtari, S. H., Kristo, F., Li, Y., Shioda, T., Cohen, D. E., Gerszten, R. E., and Näär, A. M. (2010) MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328, 1566-1569
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
Kristo, F.2
Li, Y.3
Shioda, T.4
Cohen, D.E.5
Gerszten, R.E.6
Näär, A.M.7
-
90
-
-
77953787211
-
MiR-33 contributes to the regulation of cholesterol homeostasis
-
Rayner, K. J., Suárez, Y., Dávalos, A., Parathath, S., Fitzgerald, M. L., Tamehiro, N., Fisher, E. A., Moore, K. J., and Fernández-Hernando, C. (2010) MiR-33 contributes to the regulation of cholesterol homeostasis. Science 328, 1570-1573
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
Suárez, Y.2
Dávalos, A.3
Parathath, S.4
Fitzgerald, M.L.5
Tamehiro, N.6
Fisher, E.A.7
Moore, K.J.8
Fernández-Hernando, C.9
-
91
-
-
33646366123
-
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma
-
Smith, R., Owen, L. A., Trem, D. J., Wong, J. S., Whangbo, J. S., Golub, T. R., and Lessnick, S. L. (2006) Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell 9, 405-416
-
(2006)
Cancer Cell
, vol.9
, pp. 405-416
-
-
Smith, R.1
Owen, L.A.2
Trem, D.J.3
Wong, J.S.4
Whangbo, J.S.5
Golub, T.R.6
Lessnick, S.L.7
-
92
-
-
79551572113
-
NKX2.2 suppresses self-renewal of glioma-initiating cells
-
Muraguchi, T., Tanaka, S., Yamada, D., Tamase, A., Nakada, M., Nakamura, H., Hoshii, T., Ooshio, T., Tadokoro, Y., Naka, K., Ino, Y., Todo, T., Kuratsu, J., Saya, H., Hamada, J., and Hirao, A. (2011) NKX2.2 suppresses self-renewal of glioma-initiating cells. Cancer Res. 71, 1135-1145
-
(2011)
Cancer Res
, vol.71
, pp. 1135-1145
-
-
Muraguchi, T.1
Tanaka, S.2
Yamada, D.3
Tamase, A.4
Nakada, M.5
Nakamura, H.6
Hoshii, T.7
Ooshio, T.8
Tadokoro, Y.9
Naka, K.10
Ino, Y.11
Todo, T.12
Kuratsu, J.13
Saya, H.14
Hamada, J.15
Hirao, A.16
-
93
-
-
24944524154
-
Positive thyroid transcription factor 1 staining strongly correlates with survival of patients with adenocarcinoma of the lung
-
Barlési, F., Pinot, D., Legoffic, A., Doddoli, C., Chetaille, B., Torre, J. P., and Astoul, P. (2005) Positive thyroid transcription factor 1 staining strongly correlates with survival of patients with adenocarcinoma of the lung. Br. J. Cancer 93, 450-452
-
(2005)
Br. J. Cancer
, vol.93
, pp. 450-452
-
-
Barlési, F.1
Pinot, D.2
Legoffic, A.3
Doddoli, C.4
Chetaille, B.5
Torre, J.P.6
Astoul, P.7
-
94
-
-
33750584521
-
Thyroid transcription factor 1 - A new prognostic factor in lung cancer: A meta-analysis
-
Berghmans, T., Paesmans, M., Mascaux, C., Martin, B., Meert, A. P., Haller, A., Lafitte, J. J., and Sculier, J. P. (2006) Thyroid transcription factor 1-a new prognostic factor in lung cancer: a meta-analysis. Ann. Oncol. 17, 1673-1676
-
(2006)
Ann. Oncol
, vol.17
, pp. 1673-1676
-
-
Berghmans, T.1
Paesmans, M.2
Mascaux, C.3
Martin, B.4
Meert, A.P.5
Haller, A.6
Lafitte, J.J.7
Sculier, J.P.8
-
95
-
-
84859436530
-
NCBI Reference Sequences (RefSeq): Current status, new features and genome annotation policy
-
Pruitt, K. D., Tatusova, T., Brown, G. R., and Maglott, D. R. (2012) NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy. Nucleic Acids Res. 40, D130-D1355
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Pruitt, K.D.1
Tatusova, T.2
Brown, G.R.3
Maglott, D.R.4
-
96
-
-
84880878241
-
HMGA2 is a driver of tumor metastasis
-
10.1158/0008-5472.CAN-12-3848
-
Morishita, A., Zaidi, M. R., Mitoro, A., Sankarasharma, D., Szabolcs, M., Okada, Y., D'Armiento, J., and Chada, K. (2013) HMGA2 is a driver of tumor metastasis. Cancer Res. 10.1158/0008-5472.CAN-12-3848
-
(2013)
Cancer Res
-
-
Morishita, A.1
Zaidi, M.R.2
Mitoro, A.3
Sankarasharma, D.4
Szabolcs, M.5
Okada, Y.6
D'Armiento, J.7
Chada, K.8
|