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Volumn 20, Issue 8, 2006, Pages 1796-1809

Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CRE RECOMBINASE; THYROID PEROXIDASE; THYROID SPECIFIC ENHANCER BINDING PROTEIN; THYROTROPIN; UNCLASSIFIED DRUG;

EID: 33746607692     PISSN: 08888809     EISSN: 08888809     Source Type: Journal    
DOI: 10.1210/me.2005-0327     Document Type: Article
Times cited : (89)

References (45)
  • 2
    • 0032030895 scopus 로고    scopus 로고
    • Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands
    • Manley NR, Capecchi MR 1998 Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Dev Biol 195:1-15
    • (1998) Dev Biol , vol.195 , pp. 1-15
    • Manley, N.R.1    Capecchi, M.R.2
  • 3
    • 0011797324 scopus 로고    scopus 로고
    • Thyroid gland: Anatomy and development
    • DeGroot L, Jameson J, eds. Philadelphia: Saunders
    • Di Lauro R, De Felice M 2001 Thyroid gland: anatomy and development. In: DeGroot L, Jameson J, eds. Endocrinology. Philadelphia: Saunders; 1268-1278
    • (2001) Endocrinology , pp. 1268-1278
    • Di Lauro, R.1    De Felice, M.2
  • 4
    • 0032565733 scopus 로고    scopus 로고
    • Molecular events involved in differentiation of thyroid follicular cells
    • Missero C, Cobellis G, De Felice M, Di Lauro R 1998 Molecular events involved in differentiation of thyroid follicular cells. Mol Cell Endocrinol 140:37-43
    • (1998) Mol Cell Endocrinol , vol.140 , pp. 37-43
    • Missero, C.1    Cobellis, G.2    De Felice, M.3    Di Lauro, R.4
  • 5
    • 33744918272 scopus 로고    scopus 로고
    • Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid
    • Kusakabe T, Hoshi N, Kimura S 2006 Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid. Dev Dyn 235:1300-1309
    • (2006) Dev Dyn , vol.235 , pp. 1300-1309
    • Kusakabe, T.1    Hoshi, N.2    Kimura, S.3
  • 6
    • 0000938912 scopus 로고    scopus 로고
    • The thyroid gland
    • Kovacs K, Asa SL, eds. Malden, MA: Blackwell Science, Inc.
    • Murray D 1998 The thyroid gland. In: Kovacs K, Asa SL, eds. Functional endocrine pathology. Malden, MA: Blackwell Science, Inc.; 295-380
    • (1998) Functional Endocrine Pathology , pp. 295-380
    • Murray, D.1
  • 7
    • 0035202331 scopus 로고    scopus 로고
    • A unique combination of transcription factors controls differentiation of thyroid cells
    • Damante G, Tell G, Di Lauro R 2001 A unique combination of transcription factors controls differentiation of thyroid cells. Prog Nucleic Acid Res Mol Biol 66:307-356
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.66 , pp. 307-356
    • Damante, G.1    Tell, G.2    Di Lauro, R.3
  • 8
    • 0035118721 scopus 로고    scopus 로고
    • Microtubule integrity is essential for apical polarization and epithelial morphogenesis in the thyroid
    • Yap AS, Manley SW 2001 Microtubule integrity is essential for apical polarization and epithelial morphogenesis in the thyroid. Cell Motil Cytoskeleton 48:201-212
    • (2001) Cell Motil Cytoskeleton , vol.48 , pp. 201-212
    • Yap, A.S.1    Manley, S.W.2
  • 9
    • 0033017843 scopus 로고    scopus 로고
    • Influence of transforming growth factor β1 (TGF-β1) on the behaviour of porcine thyroid epithelial cells in primary culture through thrombospondin-1 synthesis
    • Claisse D, Martiny I, Chaqour B, Wegrowski Y, Petitfrere E, Schneider C, Haye B, Bellon G 1999 Influence of transforming growth factor β1 (TGF-β1) on the behaviour of porcine thyroid epithelial cells in primary culture through thrombospondin-1 synthesis. J Cell Sci 112:1405-1416
    • (1999) J Cell Sci , vol.112 , pp. 1405-1416
    • Claisse, D.1    Martiny, I.2    Chaqour, B.3    Wegrowski, Y.4    Petitfrere, E.5    Schneider, C.6    Haye, B.7    Bellon, G.8
  • 11
    • 0032911227 scopus 로고    scopus 로고
    • Regulation of the three-dimensional organization of thyroid epithelial cells into follicle structures by the matricellular protein, thrombospondin-1
    • Pellerin S, Croizet K, Rabilloud R, Feige JJ, Rousset B 1999 Regulation of the three-dimensional organization of thyroid epithelial cells into follicle structures by the matricellular protein, thrombospondin-1. Endocrinology 140:1094-1103
    • (1999) Endocrinology , vol.140 , pp. 1094-1103
    • Pellerin, S.1    Croizet, K.2    Rabilloud, R.3    Feige, J.J.4    Rousset, B.5
  • 12
    • 0034944464 scopus 로고    scopus 로고
    • Thyrocyte integration, and thyroid folliculogenesis and tissue regeneration: Perspective for thyroid tissue engineering
    • Toda S, Koike N, Sugihara H 2001 Thyrocyte integration, and thyroid folliculogenesis and tissue regeneration: perspective for thyroid tissue engineering. Pathol Int 51:403-417
    • (2001) Pathol Int , vol.51 , pp. 403-417
    • Toda, S.1    Koike, N.2    Sugihara, H.3
  • 13
    • 0027938487 scopus 로고
    • Thyroid epithelial morphogenesis in vitro: A role for bumetanide-sensitive Cl- secretion during follicular lumen development
    • Yap AS, Stevenson BR, Armstrong JW, Keast JR, Manley SW 1994 Thyroid epithelial morphogenesis in vitro: a role for bumetanide-sensitive Cl- secretion during follicular lumen development. Exp Cell Res 213:319-326
    • (1994) Exp Cell Res , vol.213 , pp. 319-326
    • Yap, A.S.1    Stevenson, B.R.2    Armstrong, J.W.3    Keast, J.R.4    Manley, S.W.5
  • 14
    • 0034457484 scopus 로고    scopus 로고
    • Formation of three-dimensional thyroid follicle-like structures by polarized FRT cells made communication competent by transfection and stable expression of the connexin-32 gene
    • Tonoli H, Flachon V, Audebet C, Calle A, Jarry-Guichard T, Statuto M, Rousset B, Munari-Silem Y 2000 Formation of three-dimensional thyroid follicle-like structures by polarized FRT cells made communication competent by transfection and stable expression of the connexin-32 gene. Endocrinology 141:1403-1413
    • (2000) Endocrinology , vol.141 , pp. 1403-1413
    • Tonoli, H.1    Flachon, V.2    Audebet, C.3    Calle, A.4    Jarry-Guichard, T.5    Statuto, M.6    Rousset, B.7    Munari-Silem, Y.8
  • 15
    • 0025010740 scopus 로고
    • Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity
    • Guazzi S, Price M, De Felice M, Damante G, Mattei MG, Di Lauro R 1990 Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J 9:3631-3639
    • (1990) EMBO J , vol.9 , pp. 3631-3639
    • Guazzi, S.1    Price, M.2    De Felice, M.3    Damante, G.4    Mattei, M.G.5    Di Lauro, R.6
  • 16
    • 0026049382 scopus 로고
    • Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1
    • Mizuno K, Gonzalez FJ, Kimura S 1991 Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1. Mol Cell Biol 11:4927-4933
    • (1991) Mol Cell Biol , vol.11 , pp. 4927-4933
    • Mizuno, K.1    Gonzalez, F.J.2    Kimura, S.3
  • 17
    • 18344404449 scopus 로고    scopus 로고
    • TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation
    • Zannini M, Avantaggiato V, Biffali E, Arnone MI, Sato K, Pischetola M, Taylor BA, Phillips SJ, Simeone A, Di Lauro R 1997 TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J 16:3185-3197
    • (1997) EMBO J , vol.16 , pp. 3185-3197
    • Zannini, M.1    Avantaggiato, V.2    Biffali, E.3    Arnone, M.I.4    Sato, K.5    Pischetola, M.6    Taylor, B.A.7    Phillips, S.J.8    Simeone, A.9    Di Lauro, R.10
  • 18
    • 0025084237 scopus 로고
    • Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
    • Plachov D, Chowdhury K, Walther C, Simon D, Guenet JL, Gruss P 1990 Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development 110:643-651
    • (1990) Development , vol.110 , pp. 643-651
    • Plachov, D.1    Chowdhury, K.2    Walther, C.3    Simon, D.4    Guenet, J.L.5    Gruss, P.6
  • 20
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • Kimura S, Hara Y, Pineau T, Fernandez-Salguero P, Fox CH, Ward JM, Gonzalez FJ 1996 The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev 10:60-69
    • (1996) Genes Dev , vol.10 , pp. 60-69
    • Kimura, S.1    Hara, Y.2    Pineau, T.3    Fernandez-Salguero, P.4    Fox, C.H.5    Ward, J.M.6    Gonzalez, F.J.7
  • 21
    • 0031777309 scopus 로고    scopus 로고
    • Follicular cells of the thyroid gland require Pax8 gene function
    • Mansouri A, Chowdhury K, Gruss P 1998 Follicular cells of the thyroid gland require Pax8 gene function. Nat Genet 19:87-90
    • (1998) Nat Genet , vol.19 , pp. 87-90
    • Mansouri, A.1    Chowdhury, K.2    Gruss, P.3
  • 22
    • 0033135419 scopus 로고    scopus 로고
    • Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos
    • Minoo P, Su G, Drum H, Bringas P, Kimura S 1999 Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev Biol 209:60-71
    • (1999) Dev Biol , vol.209 , pp. 60-71
    • Minoo, P.1    Su, G.2    Drum, H.3    Bringas, P.4    Kimura, S.5
  • 23
    • 0032707150 scopus 로고    scopus 로고
    • Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia
    • Kimura S, Ward JM, Minoo P 1999 Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia. Biochimie 81:321-327
    • (1999) Biochimie , vol.81 , pp. 321-327
    • Kimura, S.1    Ward, J.M.2    Minoo, P.3
  • 25
    • 0242267051 scopus 로고    scopus 로고
    • Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor
    • Moeller LC, Kimura S, Kusakabe T, Liao XH, Van Sande J, Refetoff S 2003 Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor. Mol Endocrinol 17:2295-2302
    • (2003) Mol Endocrinol , vol.17 , pp. 2295-2302
    • Moeller, L.C.1    Kimura, S.2    Kusakabe, T.3    Liao, X.H.4    Van Sande, J.5    Refetoff, S.6
  • 27
    • 0033396462 scopus 로고    scopus 로고
    • Improved radioimmunoassay for measurement of mouse thyrotropin in serum: Strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone
    • Pohlenz J, Maqueem A, Cua K, Weiss RE, Van Sande J, Refetoff S 1999 Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone. Thyroid 9:1265-1271
    • (1999) Thyroid , vol.9 , pp. 1265-1271
    • Pohlenz, J.1    Maqueem, A.2    Cua, K.3    Weiss, R.E.4    Van Sande, J.5    Refetoff, S.6
  • 28
    • 0025344063 scopus 로고
    • Reconstruction of thyroid follicles from isolated porcine follicle cells in three-dimensional collagen gel culture
    • Toda S, Sugihara H 1990 Reconstruction of thyroid follicles from isolated porcine follicle cells in three-dimensional collagen gel culture. Endocrinology 126:2027-2034
    • (1990) Endocrinology , vol.126 , pp. 2027-2034
    • Toda, S.1    Sugihara, H.2
  • 29
    • 0031058344 scopus 로고    scopus 로고
    • Role of the thyroid-specific enhancer-binding protein in transcription, development and differentiation
    • Kimura S 1997 Role of the thyroid-specific enhancer-binding protein in transcription, development and differentiation. Eur J Endocrinol 136:128-136
    • (1997) Eur J Endocrinol , vol.136 , pp. 128-136
    • Kimura, S.1
  • 30
    • 0033005644 scopus 로고    scopus 로고
    • In vivo expression of thyroid transcription factor-1 RNA and its relation to thyroid function and follicular heterogeneity: Identification of follicular thyroglobulin as a feedback suppressor of thyroid transcription factor-1 RNA levels and thyroglobulin synthesis
    • Suzuki K, Mori A, Lavaroni S, Miyagi E, Ulianich L, Katoh R, Kawaoi A, Kohn LD 1999 In vivo expression of thyroid transcription factor-1 RNA and its relation to thyroid function and follicular heterogeneity: identification of follicular thyroglobulin as a feedback suppressor of thyroid transcription factor-1 RNA levels and thyroglobulin synthesis. Thyroid 9:319-331
    • (1999) Thyroid , vol.9 , pp. 319-331
    • Suzuki, K.1    Mori, A.2    Lavaroni, S.3    Miyagi, E.4    Ulianich, L.5    Katoh, R.6    Kawaoi, A.7    Kohn, L.D.8
  • 31
    • 0026593301 scopus 로고
    • Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression
    • Francis-Lang H, Price M, Polycarpou-Schwarz M, Di Lauro R 1992 Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Mol Cell Biol 12:576-588
    • (1992) Mol Cell Biol , vol.12 , pp. 576-588
    • Francis-Lang, H.1    Price, M.2    Polycarpou-Schwarz, M.3    Di Lauro, R.4
  • 32
    • 0025200299 scopus 로고
    • Characterization of a thyroid-specific enhancer located 5.5 kilobase pairs upstream of the human thyroid peroxidase gene
    • Kikkawa F, Gonzalez FJ, Kimura S 1990 Characterization of a thyroid-specific enhancer located 5.5 kilobase pairs upstream of the human thyroid peroxidase gene. Mol Cell Biol 10:6216-6224
    • (1990) Mol Cell Biol , vol.10 , pp. 6216-6224
    • Kikkawa, F.1    Gonzalez, F.J.2    Kimura, S.3
  • 33
    • 0024425390 scopus 로고
    • A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
    • Civitareale D, Lonigro R, Sinclair AJ, Di Lauro R 1989 A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter. EMBO J 8:2537-2542
    • (1989) EMBO J , vol.8 , pp. 2537-2542
    • Civitareale, D.1    Lonigro, R.2    Sinclair, A.J.3    Di Lauro, R.4
  • 34
    • 85003066115 scopus 로고
    • Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene
    • Civitareale D, Castelli MP, Falasca P, Saiardi A 1993 Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene. Mol Endocrinol 7:1589-1595
    • (1993) Mol Endocrinol , vol.7 , pp. 1589-1595
    • Civitareale, D.1    Castelli, M.P.2    Falasca, P.3    Saiardi, A.4
  • 35
    • 0027933717 scopus 로고
    • Thyroid-specific expression and cyclic adenosine 3′,5′- monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1
    • Shimura H, Okajima F, Ikuyama S, Shimura Y, Kimura S, Saji M, Kohn LD 1994 Thyroid-specific expression and cyclic adenosine 3′,5′- monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1. Mol Endocrinol 8:1049-1069
    • (1994) Mol Endocrinol , vol.8 , pp. 1049-1069
    • Shimura, H.1    Okajima, F.2    Ikuyama, S.3    Shimura, Y.4    Kimura, S.5    Saji, M.6    Kohn, L.D.7
  • 36
    • 0030880728 scopus 로고    scopus 로고
    • Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene
    • Endo T, Kaneshige M, Nakazato M, Ohmori M, Harii N, Onaya T 1997 Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene. Mol Endocrinol 11:1747-1755
    • (1997) Mol Endocrinol , vol.11 , pp. 1747-1755
    • Endo, T.1    Kaneshige, M.2    Nakazato, M.3    Ohmori, M.4    Harii, N.5    Onaya, T.6
  • 37
    • 0034687754 scopus 로고    scopus 로고
    • An alternative, nonapoptotic form of programmed cell death
    • USA
    • Sperandio S, de Belle I, Bredesen DE 2000 An alternative, nonapoptotic form of programmed cell death. Proc Natl Acad Sci USA 97:14376-14381
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 14376-14381
    • Sperandio, S.1    De Belle, I.2    Bredesen, D.E.3
  • 38
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ, Emr SD 2000 Autophagy as a regulated pathway of cellular degradation. Science 290:1717-1721
    • (2000) Science , vol.290 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 39
    • 0032971161 scopus 로고    scopus 로고
    • Caspase-independent programmed cell death with necrotic morphology
    • Kitanaka C, Kuchino Y 1999 Caspase-independent programmed cell death with necrotic morphology. Cell Death Differ 6:508-515
    • (1999) Cell Death Differ , vol.6 , pp. 508-515
    • Kitanaka, C.1    Kuchino, Y.2
  • 41
    • 0031764280 scopus 로고    scopus 로고
    • Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: Evidence of autoregulation
    • Oguchi H, Kimura S 1998 Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: evidence of autoregulation. Endocrinology 139:1999-2006
    • (1998) Endocrinology , vol.139 , pp. 1999-2006
    • Oguchi, H.1    Kimura, S.2


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