-
1
-
-
84864392111
-
Suicide gene therapy in cancer: Where do we stand now?
-
Duarte S, Carle G, Faneca H, de Lima MC, Pierrefite-Carle V. Suicide gene therapy in cancer: where do we stand now? Cancer Lett 2012; 324(2): 160-170.
-
(2012)
Cancer Lett
, vol.324
, Issue.2
, pp. 160-170
-
-
Duarte, S.1
Carle, G.2
Faneca, H.3
De Lima, M.C.4
Pierrefite-Carle, V.5
-
2
-
-
84881108625
-
Biological delivery approaches for gene therapy: Strategies to potentiate efficacy and enhance specificity
-
Mohit E, Rafati S. Biological delivery approaches for gene therapy: strategies to potentiate efficacy and enhance specificity. Mol Immunol 2013; 56(4): 599-611.
-
(2013)
Mol Immunol
, vol.56
, Issue.4
, pp. 599-611
-
-
Mohit, E.1
Rafati, S.2
-
3
-
-
80455162464
-
Inducible apoptosis as a safety switch for adoptive cell therapy
-
Di Stasi A, Tey SK, Dotti G, Fujita Y, Kennedy-Nasser A, Martinez C et al. Inducible apoptosis as a safety switch for adoptive cell therapy. N Engl J Med 2011; 365(18): 1673-1683.
-
(2011)
N Engl J Med
, vol.365
, Issue.18
, pp. 1673-1683
-
-
Di Stasi, A.1
Tey, S.K.2
Dotti, G.3
Fujita, Y.4
Kennedy-Nasser, A.5
Martinez, C.6
-
4
-
-
77956627600
-
An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies
-
Ramos CA, Asgari Z, Liu E, Yvon E, Heslop HE, Rooney CM et al. An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies. Stem Cells 2010; 28(6): 1107-1115.
-
(2010)
Stem Cells
, vol.28
, Issue.6
, pp. 1107-1115
-
-
Ramos, C.A.1
Asgari, Z.2
Liu, E.3
Yvon, E.4
Heslop, H.E.5
Rooney, C.M.6
-
5
-
-
19344365874
-
An inducible caspase 9 safety switch for t-cell therapy
-
Straathof KC, Pule MA, Yotnda P, Dotti G, Vanin EF, Brenner MK et al. An inducible caspase 9 safety switch for T-cell therapy. Blood 2005; 105(11): 4247-4254.
-
(2005)
Blood
, vol.105
, Issue.11
, pp. 4247-4254
-
-
Straathof, K.C.1
Pule, M.A.2
Yotnda, P.3
Dotti, G.4
Vanin, E.F.5
Brenner, M.K.6
-
6
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM et al. A unified model for apical caspase activation. Mol Cell 2003; 11(2): 529-541.
-
(2003)
Mol Cell
, vol.11
, Issue.2
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
7
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007; 8(5): 405-413.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.5
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
8
-
-
0031036872
-
Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997; 275 (5303): 1129-1132.
-
(1997)
Science
, vol.275
, Issue.5303
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
-
9
-
-
79955992274
-
Bortezomib primes neuroblastoma cells for trail-induced apoptosis by linking the death receptor to the mitochondrial pathway
-
Naumann I, Kappler R, von Schweinitz D, Debatin KM, Fulda S. Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway. Clin Cancer Res 2011; 17(10): 3204-3218.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.10
, pp. 3204-3218
-
-
Naumann, I.1
Kappler, R.2
Von Schweinitz, D.3
Debatin, K.M.4
Fulda, S.5
-
10
-
-
0642378063
-
Overcoming drug resistance in multiple myeloma: The emergence of therapeutic approaches to induce apoptosis
-
Yang HH, Ma MH, Vescio RA, Berenson JR. Overcoming drug resistance in multiple myeloma: the emergence of therapeutic approaches to induce apoptosis. J Clin Oncol 2003; 21(22): 4239-4247.
-
(2003)
J Clin Oncol
, vol.21
, Issue.22
, pp. 4239-4247
-
-
Yang, H.H.1
Ma, M.H.2
Vescio, R.A.3
Berenson, J.R.4
-
11
-
-
34347375499
-
Npi-0052, a novel proteasome inhibitor, induces caspase-8 and ros-dependent apoptosis alone and in combination with hdac inhibitors in leukemia cells
-
Miller CP, Ban K, Dujka ME, McConkey DJ, Munsell M, Palladino M et al. NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells. Blood 2007; 110(1): 267-277.
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 267-277
-
-
Miller, C.P.1
Ban, K.2
Dujka, M.E.3
McConkey, D.J.4
Munsell, M.5
Palladino, M.6
-
12
-
-
20444491066
-
Ps-341-mediated selective targeting of multiple myeloma cells by synergistic increase in ionizing radiation-induced apoptosis
-
Goel A, Dispenzieri A, Greipp PR, Witzig TE, Mesa RA, Russell SJ. PS-341-mediated selective targeting of multiple myeloma cells by synergistic increase in ionizing radiation-induced apoptosis. Exp Hematol 2005; 33(7): 784-795.
-
(2005)
Exp Hematol
, vol.33
, Issue.7
, pp. 784-795
-
-
Goel, A.1
Dispenzieri, A.2
Greipp, P.R.3
Witzig, T.E.4
Mesa, R.A.5
Russell, S.J.6
-
13
-
-
53049083867
-
Mechanisms of proteasome inhibitor action and resistance in cancer
-
McConkey DJ, Zhu K. Mechanisms of proteasome inhibitor action and resistance in cancer. Drug Resist Updat 2008; 11(4-5): 164-179.
-
(2008)
Drug Resist Updat
, vol.11
, Issue.4-5
, pp. 164-179
-
-
McConkey, D.J.1
Zhu, K.2
-
14
-
-
77649185403
-
Therapeutic potential of human mesenchymal stem cells producing il-12 in a mouse xenograft model of renal cell carcinoma
-
Gao P, Ding Q, Wu Z, Jiang H, Fang Z. Therapeutic potential of human mesenchymal stem cells producing IL-12 in a mouse xenograft model of renal cell carcinoma. Cancer Lett 2010; 290(2): 157-166.
-
(2010)
Cancer Lett
, vol.290
, Issue.2
, pp. 157-166
-
-
Gao, P.1
Ding, Q.2
Wu, Z.3
Jiang, H.4
Fang, Z.5
-
15
-
-
77951749301
-
Adiposederived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy
-
Grisendi G, Bussolari R, Cafarelli L, Petak I, Rasini V, Veronesi E et al. Adiposederived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy. Cancer Res 2010; 70(9): 3718-3729.
-
(2010)
Cancer Res
, vol.70
, Issue.9
, pp. 3718-3729
-
-
Grisendi, G.1
Bussolari, R.2
Cafarelli, L.3
Petak, I.4
Rasini, V.5
Veronesi, E.6
-
16
-
-
77249122967
-
Hsv-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells
-
Matuskova M, Hlubinova K, Pastorakova A, Hunakova L, Altanerova V, Altaner C et al. HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. Cancer Lett 2010; 290(1): 58-67.
-
(2010)
Cancer Lett
, vol.290
, Issue.1
, pp. 58-67
-
-
Matuskova, M.1
Hlubinova, K.2
Pastorakova, A.3
Hunakova, L.4
Altanerova, V.5
Altaner, C.6
-
17
-
-
0036644833
-
Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
-
Studeny M, Marini FC, Champlin RE, Zompetta C, Fidler IJ, Andreeff M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 2002; 62(13): 3603-3608.
-
(2002)
Cancer Res
, vol.62
, Issue.13
, pp. 3603-3608
-
-
Studeny, M.1
Marini, F.C.2
Champlin, R.E.3
Zompetta, C.4
Fidler, I.J.5
Andreeff, M.6
-
18
-
-
1242289002
-
Systemic dissemination of viral vectors during intratumoral injection
-
Wang Y, Hu JK, Krol A, Li YP, Li CY, Yuan F. Systemic dissemination of viral vectors during intratumoral injection. Mol Cancer Ther 2003; 2(11): 1233-1242.
-
(2003)
Mol Cancer Ther
, vol.2
, Issue.11
, pp. 1233-1242
-
-
Wang, Y.1
Hu, J.K.2
Krol, A.3
Li, Y.P.4
Li, C.Y.5
Yuan, F.6
-
19
-
-
0031034030
-
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
-
Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum Gene Ther 1997; 8(1): 37-44.
-
(1997)
Hum Gene Ther
, vol.8
, Issue.1
, pp. 37-44
-
-
Worgall, S.1
Wolff, G.2
Falck-Pedersen, E.3
Crystal, R.G.4
-
20
-
-
77949659742
-
Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells
-
Dembinski JL, Spaeth EL, Fueyo J, Gomez-Manzano C, Studeny M, Andreeff M et al. Reduction of nontarget infection and systemic toxicity by targeted delivery of conditionally replicating viruses transported in mesenchymal stem cells. Cancer Gene Ther 2010; 17(4): 289-297.
-
(2010)
Cancer Gene Ther
, vol.17
, Issue.4
, pp. 289-297
-
-
Dembinski, J.L.1
Spaeth, E.L.2
Fueyo, J.3
Gomez-Manzano, C.4
Studeny, M.5
Andreeff, M.6
-
21
-
-
66249096305
-
Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect
-
Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev 2009; 18(5): 683-692.
-
(2009)
Stem Cells Dev
, vol.18
, Issue.5
, pp. 683-692
-
-
Fischer, U.M.1
Harting, M.T.2
Jimenez, F.3
Monzon-Posadas, W.O.4
Xue, H.5
Savitz, S.I.6
-
22
-
-
77950909661
-
Stem cells as vectors for antitumour therapy
-
Loebinger MR, Janes SM. Stem cells as vectors for antitumour therapy. Thorax 2010; 65(4): 362-369.
-
(2010)
Thorax
, vol.65
, Issue.4
, pp. 362-369
-
-
Loebinger, M.R.1
Janes, S.M.2
-
23
-
-
42549114180
-
Mesenchymal stem cells: An emerging tool for cancer targeting and therapy
-
Fritz V, Jorgensen C. Mesenchymal stem cells: an emerging tool for cancer targeting and therapy. Curr Stem Cell Res Ther 2008; 3(1): 32-42.
-
(2008)
Curr Stem Cell Res Ther
, vol.3
, Issue.1
, pp. 32-42
-
-
Fritz, V.1
Jorgensen, C.2
-
24
-
-
71549114206
-
Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles
-
Loebinger MR, Kyrtatos PG, Turmaine M, Price AN, Pankhurst Q, Lythgoe MF et al. Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles. Cancer Res 2009; 69(23): 8862-8867.
-
(2009)
Cancer Res
, vol.69
, Issue.23
, pp. 8862-8867
-
-
Loebinger, M.R.1
Kyrtatos, P.G.2
Turmaine, M.3
Price, A.N.4
Pankhurst, Q.5
Lythgoe, M.F.6
-
25
-
-
34447310075
-
Inducible caspase 9 suicide gene to improve the safety of allodepleted t cells after haploidentical stem cell transplantation
-
Tey SK, Dotti G, Rooney CM, Heslop HE, Brenner MK. Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation. Biol Blood Marrow Transplant 2007; 13(8): 913-924.
-
(2007)
Biol Blood Marrow Transplant
, vol.13
, Issue.8
, pp. 913-924
-
-
Tey, S.K.1
Dotti, G.2
Rooney, C.M.3
Heslop, H.E.4
Brenner, M.K.5
-
26
-
-
33845256434
-
T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature b lymphocyte-derived malignant cells
-
Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C et al. T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 2006; 108(12): 3890-3897.
-
(2006)
Blood
, vol.108
, Issue.12
, pp. 3890-3897
-
-
Vera, J.1
Savoldo, B.2
Vigouroux, S.3
Biagi, E.4
Pule, M.5
Rossig, C.6
-
27
-
-
0025868555
-
Structure and domain organization of the cd19 antigen of human, mouse, and guinea pig b lymphocytes. Conservation of the extensive cytoplasmic domain
-
Zhou LJ, Ord DC, Hughes AL, Tedder TF. Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. J Immunol 1991; 147(4): 1424-1432.
-
(1991)
J Immunol
, vol.147
, Issue.4
, pp. 1424-1432
-
-
Zhou, L.J.1
Ord, D.C.2
Hughes, A.L.3
Tedder, T.F.4
-
28
-
-
0034919257
-
Intravenous safety and pharmacokinetics of a novel dimerizer drug, ap1903, in healthy volunteers
-
Iuliucci JD, Oliver SD, Morley S, Ward C, Ward J, Dalgarno D et al. Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteers. J Clin Pharmacol 2001; 41(8): 870-879.
-
(2001)
J Clin Pharmacol
, vol.41
, Issue.8
, pp. 870-879
-
-
Iuliucci, J.D.1
Oliver, S.D.2
Morley, S.3
Ward, C.4
Ward, J.5
Dalgarno, D.6
-
29
-
-
28444436266
-
Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma
-
Lonial S, Waller EK, Richardson PG, Jagannath S, Orlowski RZ, Giver CR et al. Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma. Blood 2005; 106(12): 3777-3784.
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3777-3784
-
-
Lonial, S.1
Waller, E.K.2
Richardson, P.G.3
Jagannath, S.4
Orlowski, R.Z.5
Giver, C.R.6
-
30
-
-
0035902601
-
Ubiquitin-protein ligase activity of x-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-Apoptotic effect in fas-induced cell death
-
Suzuki Y, Nakabayashi Y, Takahashi R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-Apoptotic effect in Fas-induced cell death. Proc Natl Acad Sci USA 2001; 98(15): 8662-8667.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.15
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
31
-
-
41549132691
-
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells
-
Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger PK. Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol Cell 2008; 30(1): 11-25.
-
(2008)
Mol Cell
, vol.30
, Issue.1
, pp. 11-25
-
-
Albeck, J.G.1
Burke, J.M.2
Aldridge, B.B.3
Zhang, M.4
Lauffenburger, D.A.5
Sorger, P.K.6
-
32
-
-
33748941571
-
Systems analysis of effector caspase activation and its control by x-linked inhibitor of apoptosis protein
-
Rehm M, Huber HJ, Dussmann H, Prehn JH. Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J 2006; 25(18): 4338-4349.
-
(2006)
EMBO J
, vol.25
, Issue.18
, pp. 4338-4349
-
-
Rehm, M.1
Huber, H.J.2
Dussmann, H.3
Prehn, J.H.4
-
33
-
-
17344365922
-
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase i clinical trial in malignant mesothelioma
-
Sterman DH, Treat J, Litzky LA, Amin KM, Coonrod L, Molnar-Kimber K et al. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum Gene Ther 1998; 9(7): 1083-1092.
-
(1998)
Hum Gene Ther
, vol.9
, Issue.7
, pp. 1083-1092
-
-
Sterman, D.H.1
Treat, J.2
Litzky, L.A.3
Amin, K.M.4
Coonrod, L.5
Molnar-Kimber, K.6
-
34
-
-
68949197421
-
Phase i and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors
-
Xu F, Li S, Li XL, Guo Y, Zou BY, Xu R et al. Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors. Cancer Gene Ther 2009; 16(9): 723-730.
-
(2009)
Cancer Gene Ther
, vol.16
, Issue.9
, pp. 723-730
-
-
Xu, F.1
Li, S.2
Li, X.L.3
Guo, Y.4
Zou, B.Y.5
Xu, R.6
-
35
-
-
0034320107
-
Adenoviral-mediated suicide gene therapy for ovarian cancer
-
Alvarez RD, Gomez-Navarro J, Wang M, Barnes MN, Strong TV, Arani RB et al. Adenoviral-mediated suicide gene therapy for ovarian cancer. Mol Ther 2000; 2(5): 524-530.
-
(2000)
Mol Ther
, vol.2
, Issue.5
, pp. 524-530
-
-
Alvarez, R.D.1
Gomez-Navarro, J.2
Wang, M.3
Barnes, M.N.4
Strong, T.V.5
Arani, R.B.6
-
36
-
-
80053614471
-
In vivo tracking of 111in-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis
-
Gholamrezanezhad A, Mirpour S, Bagheri M, Mohamadnejad M, Alimoghaddam K, Abdolahzadeh L et al. In vivo tracking of 111In-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis. Nucl Med Biol 2011; 38 (7): 961-967.
-
(2011)
Nucl Med Biol
, vol.38
, Issue.7
, pp. 961-967
-
-
Gholamrezanezhad, A.1
Mirpour, S.2
Bagheri, M.3
Mohamadnejad, M.4
Alimoghaddam, K.5
Abdolahzadeh, L.6
-
37
-
-
2342514719
-
The expansion and biological characteristics of human mesenchymal stem cells]
-
Zhou DH, Huang SL, Wu YF, Wei J, Chen GY, Li Y et al. [The expansion and biological characteristics of human mesenchymal stem cells]. Zhonghua Er Ke Za Zhi 2003; 41(8): 607-610.
-
(2003)
Zhonghua Er Ke Za Zhi
, vol.41
, Issue.8
, pp. 607-610
-
-
Zhou, D.H.1
Huang, S.L.2
Wu, Y.F.3
Wei, J.4
Chen, G.Y.5
Li, Y.6
-
38
-
-
68549117003
-
Histocompatibility testing of cultivated human bone marrow stromal cells-A promising step towards pre-clinical screening for allogeneic stem cell therapy
-
Koppula PR, Chelluri LK, Polisetti N, Vemuganti GK. Histocompatibility testing of cultivated human bone marrow stromal cells-A promising step towards pre-clinical screening for allogeneic stem cell therapy. Cell Immunol 2009; 259(1): 61-65.
-
(2009)
Cell Immunol
, vol.259
, Issue.1
, pp. 61-65
-
-
Koppula, P.R.1
Chelluri, L.K.2
Polisetti, N.3
Vemuganti, G.K.4
-
39
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46(10): 5276-5281.
-
(1986)
Cancer Res
, vol.46
, Issue.10
, pp. 5276-5281
-
-
Moolten, F.L.1
-
40
-
-
0033119291
-
Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts
-
Kievit E, Bershad E, Ng E, Sethna P, Dev I, Lawrence TS et al. Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts. Cancer Res 1999; 59(7): 1417-1421.
-
(1999)
Cancer Res
, vol.59
, Issue.7
, pp. 1417-1421
-
-
Kievit, E.1
Bershad, E.2
Ng, E.3
Sethna, P.4
Dev, I.5
Lawrence, T.S.6
-
41
-
-
0026599586
-
Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
-
Mullen CA, Kilstrup M, Blaese RM. Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. Proc Natl Acad Sci USA 1992; 89(1): 33-37.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.1
, pp. 33-37
-
-
Mullen, C.A.1
Kilstrup, M.2
Blaese, R.M.3
-
42
-
-
0027483695
-
The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman SM, Abboud CN, Whartenby KA, Packman CH, Koeplin DS, Moolten FL et al. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53(21): 5274-5283.
-
(1993)
Cancer Res
, vol.53
, Issue.21
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
Packman, C.H.4
Koeplin, D.S.5
Moolten, F.L.6
-
43
-
-
0030956975
-
Limitations of retrovirus-mediated hsv-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo
-
Zhang L, Wikenheiser KA, Whitsett JA. Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo. Hum Gene Ther 1997; 8(5): 563-574.
-
(1997)
Hum Gene Ther
, vol.8
, Issue.5
, pp. 563-574
-
-
Zhang, L.1
Wikenheiser, K.A.2
Whitsett, J.A.3
-
44
-
-
0035106088
-
Immunedependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
-
Agard C, Ligeza C, Dupas B, Izembart A, El Kouri C, Moullier P et al. Immunedependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther 2001; 8(2): 128-136.
-
(2001)
Cancer Gene Ther
, vol.8
, Issue.2
, pp. 128-136
-
-
Agard, C.1
Ligeza, C.2
Dupas, B.3
Izembart, A.4
El Kouri, C.5
Moullier, P.6
-
45
-
-
34249748406
-
The potential immunogenicity of the tk suicide gene does not prevent full clinical benefit associated with the use of tk-transduced donor lymphocytes in hsct for hematologic malignancies
-
Traversari C, Marktel S, Magnani Z, Mangia P, Russo V, Ciceri F et al. The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies. Blood 2007; 109(11): 4708-4715.
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4708-4715
-
-
Traversari, C.1
Marktel, S.2
Magnani, Z.3
Mangia, P.4
Russo, V.5
Ciceri, F.6
-
46
-
-
79952033116
-
Drug interactions and toxicities associated with the antiviral management of cytomegalovirus infection
-
Jacobsen T, Sifontis N. Drug interactions and toxicities associated with the antiviral management of cytomegalovirus infection. Am J Health Syst Pharm 2010; 67(17): 1417-1425.
-
(2010)
Am J Health Syst Pharm
, vol.67
, Issue.17
, pp. 1417-1425
-
-
Jacobsen, T.1
Sifontis, N.2
-
47
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000; 256(1): 42-49.
-
(2000)
Exp Cell Res
, vol.256
, Issue.1
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
48
-
-
35148825003
-
Extended follow-up of a phase 3 trial in relapsed multiple myeloma: Final time-toevent results of the apex trial
-
Richardson PG, Sonneveld P, Schuster M, Irwin D, Stadtmauer E, Facon T et al. Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-toevent results of the APEX trial. Blood 2007; 110(10): 3557-3560.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3557-3560
-
-
Richardson, P.G.1
Sonneveld, P.2
Schuster, M.3
Irwin, D.4
Stadtmauer, E.5
Facon, T.6
-
49
-
-
70349754173
-
A phase ii evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: A gynecologic oncology group study
-
Aghajanian C, Blessing JA, Darcy KM, Reid G, DeGeest K, Rubin SC et al. A phase II evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group study. Gynecol Oncol 2009; 115(2): 215-220.
-
(2009)
Gynecol Oncol
, vol.115
, Issue.2
, pp. 215-220
-
-
Aghajanian, C.1
Blessing, J.A.2
Darcy, K.M.3
Reid, G.4
Degeest, K.5
Rubin, S.C.6
-
50
-
-
84899061436
-
Vorinostat and bortezomib as third-line therapy in patients with advanced non-small cell lung cancer: A wisconsin oncology network phase ii study
-
Hoang T, Campbell TC, Zhang C, Kim K, Kolesar JM, Oettel KR et al. Vorinostat and bortezomib as third-line therapy in patients with advanced non-small cell lung cancer: a Wisconsin Oncology Network Phase II study. Invest New Drugs 2013; 32(1): 195-199.
-
(2013)
Invest New Drugs
, vol.32
, Issue.1
, pp. 195-199
-
-
Hoang, T.1
Campbell, T.C.2
Zhang, C.3
Kim, K.4
Kolesar, J.M.5
Oettel, K.R.6
-
51
-
-
70349243697
-
Bortezomib induces canonical nuclear factor-kappab activation in multiple myeloma cells
-
Hideshima T, Ikeda H, Chauhan D, Okawa Y, Raje N, Podar K et al. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells. Blood 2009; 114(5): 1046-1052.
-
(2009)
Blood
, vol.114
, Issue.5
, pp. 1046-1052
-
-
Hideshima, T.1
Ikeda, H.2
Chauhan, D.3
Okawa, Y.4
Raje, N.5
Podar, K.6
-
52
-
-
84904283182
-
Bortezomib inhibits proteasomal degradation of ikappabalpha and induces mitochondrial dependent apoptosis in activated b-cell diffuse large b-cell lymphoma
-
Bu R, Hussain AR, Al-Obaisi KA, Ahmed M, Uddin S, Al-Kuraya KS. Bortezomib inhibits proteasomal degradation of IkappaBalpha and induces mitochondrial dependent apoptosis in activated B-cell diffuse large B-cell lymphoma. Leuk Lymphoma 2013; 55(2): 415-424.
-
(2013)
Leuk Lymphoma
, vol.55
, Issue.2
, pp. 415-424
-
-
Bu, R.1
Hussain, A.R.2
Al-Obaisi, K.A.3
Ahmed, M.4
Uddin, S.5
Al-Kuraya, K.S.6
-
53
-
-
70949102233
-
Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system
-
Foti C, Florean C, Pezzutto A, Roncaglia P, Tomasella A, Gustincich S et al. Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system. Mol Cancer Ther 2009; 8(11): 3140-3150.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.11
, pp. 3140-3150
-
-
Foti, C.1
Florean, C.2
Pezzutto, A.3
Roncaglia, P.4
Tomasella, A.5
Gustincich, S.6
-
54
-
-
34548299555
-
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171(2): 513-524.
-
(2007)
Am J Pathol
, vol.171
, Issue.2
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
-
55
-
-
34447509647
-
Combination of the oncolytic adenovirus icovir-5 with chemotherapy provides enhanced anti-glioma effect in vivo
-
Alonso MM, Gomez-Manzano C, Jiang H, Bekele NB, Piao Y, Yung WK et al. Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo. Cancer Gene Ther 2007; 14(8): 756-761.
-
(2007)
Cancer Gene Ther
, vol.14
, Issue.8
, pp. 756-761
-
-
Alonso, M.M.1
Gomez-Manzano, C.2
Jiang, H.3
Bekele, N.B.4
Piao, Y.5
Yung, W.K.6
-
56
-
-
0030810926
-
X-linked iap is a direct inhibitor of cell-death proteases
-
Deveraux QL, Takahashi R, Salvesen GS, Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997; 388(6639): 300-304.
-
(1997)
Nature
, vol.388
, Issue.6639
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
57
-
-
0041842553
-
Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: Any single lysine or lysine pair of the small subunit is sufficient for ubiquitination
-
Chen L, Smith L, Wang Z, Smith JB. Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination. Mol Pharmacol 2003; 64(2): 334-345.
-
(2003)
Mol Pharmacol
, vol.64
, Issue.2
, pp. 334-345
-
-
Chen, L.1
Smith, L.2
Wang, Z.3
Smith, J.B.4
-
58
-
-
0032490670
-
Nuclear factor (nf)-kappab-regulated x-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis
-
Stehlik C, de Martin R, Kumabashiri I, Schmid JA, Binder BR, Lipp J. Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J Exp Med 1998; 188(1): 211-216.
-
(1998)
J Exp Med
, vol.188
, Issue.1
, pp. 211-216
-
-
Stehlik, C.1
De Martin, R.2
Kumabashiri, I.3
Schmid, J.A.4
Binder, B.R.5
Lipp, J.6
-
59
-
-
84863233878
-
Xiap is a predictor of cisplatin-based chemotherapy response and prognosis for patients with advanced head and neck cancer
-
Yang XH, Feng ZE, Yan M, Hanada S, Zuo H, Yang CZ et al. XIAP is a predictor of cisplatin-based chemotherapy response and prognosis for patients with advanced head and neck cancer. PLoS One 2012; 7(3): e31601.
-
(2012)
PLoS One
, vol.7
, Issue.3
, pp. e31601
-
-
Yang, X.H.1
Feng, Z.E.2
Yan, M.3
Hanada, S.4
Zuo, H.5
Yang, C.Z.6
-
60
-
-
84866517256
-
Xiap as a radioresistance factor and prognostic marker for radiotherapy in human rectal adenocarcinoma
-
Moussata D, Amara S, Siddeek B, Decaussin M, Hehlgans S, Paul-Bellon R et al. XIAP as a radioresistance factor and prognostic marker for radiotherapy in human rectal adenocarcinoma. Am J Pathol 2012; 181(4): 1271-1278.
-
(2012)
Am J Pathol
, vol.181
, Issue.4
, pp. 1271-1278
-
-
Moussata, D.1
Amara, S.2
Siddeek, B.3
Decaussin, M.4
Hehlgans, S.5
Paul-Bellon, R.6
-
61
-
-
79957899075
-
X-linked inhibitor of apoptosis positive nuclear labeling: A new independent prognostic biomarker of breast invasive ductal carcinoma
-
Zhang Y, Zhu J, Tang Y, Li F, Zhou H, Peng B et al. X-linked inhibitor of apoptosis positive nuclear labeling: a new independent prognostic biomarker of breast invasive ductal carcinoma. Diagn Pathol 2011; 6: 49.
-
(2011)
Diagn Pathol
, vol.6
, pp. 49
-
-
Zhang, Y.1
Zhu, J.2
Tang, Y.3
Li, F.4
Zhou, H.5
Peng, B.6
-
62
-
-
84861523366
-
Study of survivin and x-linked inhibitor of apoptosis protein (xiap) genes in acute myeloid leukemia (aml
-
Ibrahim AM, Mansour IM, Wilson MM, Mokhtar DA, Helal AM, Al Wakeel HM. Study of survivin and X-linked inhibitor of apoptosis protein (XIAP) genes in acute myeloid leukemia (AML). Lab Hematol 2012; 18(1): 1-10.
-
(2012)
Lab Hematol
, vol.18
, Issue.1
, pp. 1-10
-
-
Ibrahim, A.M.1
Mansour, I.M.2
Wilson, M.M.3
Mokhtar, D.A.4
Helal, A.M.5
Al Wakeel, H.M.6
-
63
-
-
70349329714
-
Smac mimetics as new cancer therapeutics
-
Chen DJ, Huerta S. Smac mimetics as new cancer therapeutics. Anticancer Drugs 2009; 20(8): 646-658.
-
(2009)
Anticancer Drugs
, vol.20
, Issue.8
, pp. 646-658
-
-
Chen, D.J.1
Huerta, S.2
-
64
-
-
84884521200
-
Smac mimetics in combination with trail selectively target cancer stem cells in nasopharyngeal carcinoma
-
Wu MS, Wang GF, Zhao ZQ, Liang Y, Wang HB, Wu MY et al. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Mol Cancer Ther 2013; 12(9): 1728-1737.
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.9
, pp. 1728-1737
-
-
Wu, M.S.1
Wang, G.F.2
Zhao, Z.Q.3
Liang, Y.4
Wang, H.B.5
Wu, M.Y.6
-
65
-
-
84877095096
-
Smac mimetic birinapant induces apoptosis and enhances trail potency in inflammatory breast cancer cells in an iap-dependent and tnf-Alpha-independent mechanism
-
Allensworth JL, Sauer SJ, Lyerly HK, Morse MA, Devi GR. Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-Alpha-independent mechanism. Breast Cancer Res Treat 2013; 137(2): 359-371.
-
(2013)
Breast Cancer Res Treat
, vol.137
, Issue.2
, pp. 359-371
-
-
Allensworth, J.L.1
Sauer, S.J.2
Lyerly, H.K.3
Morse, M.A.4
Devi, G.R.5
-
66
-
-
70749151909
-
A smac-mimetic sensitizes prostate cancer cells to trail-induced apoptosis via modulating both iaps and nf-kappab
-
Dai Y, Liu M, Tang W, Li Y, Lian J, Lawrence TS et al. A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB. BMC Cancer 2009; 9: 392.
-
(2009)
BMC Cancer
, vol.9
, pp. 392
-
-
Dai, Y.1
Liu, M.2
Tang, W.3
Li, Y.4
Lian, J.5
Lawrence, T.S.6
-
67
-
-
27744526342
-
A small molecule smac-mimic compound induces apoptosis and sensitizes trail-And etoposide-induced apoptosis in breast cancer cells
-
Bockbrader KM, Tan M, Sun Y. A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL-And etoposide-induced apoptosis in breast cancer cells. Oncogene 2005; 24(49): 7381-7388.
-
(2005)
Oncogene
, vol.24
, Issue.49
, pp. 7381-7388
-
-
Bockbrader, K.M.1
Tan, M.2
Sun, Y.3
-
68
-
-
71549150594
-
Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus delta24-rgd to human gliomas
-
Yong RL, Shinojima N, Fueyo J, Gumin J, Vecil GG, Marini FC et al. Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas. Cancer Res 2009; 69(23): 8932-8940.
-
(2009)
Cancer Res
, vol.69
, Issue.23
, pp. 8932-8940
-
-
Yong, R.L.1
Shinojima, N.2
Fueyo, J.3
Gumin, J.4
Vecil, G.G.5
Marini, F.C.6
-
69
-
-
30644457691
-
Combined hsv-tk/il-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
-
Colombo F, Barzon L, Franchin E, Pacenti M, Pinna V, Danieli D et al. Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results. Cancer Gene Ther 2005; 12(10): 835-848.
-
(2005)
Cancer Gene Ther
, vol.12
, Issue.10
, pp. 835-848
-
-
Colombo, F.1
Barzon, L.2
Franchin, E.3
Pacenti, M.4
Pinna, V.5
Danieli, D.6
|