Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: Any single lysine or lysine pair of the small subunit is sufficient for ubiquitination

Molecular Pharmacology

Volumn 64, Issue 2, 2003, Pages 334-345

  Chen, Lei ^a,b   Smith, Lucinda ^a   Wang, Zhi ^a   Smith, Jeffrey B ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CASPASE 3; CASPASE 8; CASPASE 9; ENZYME PRECURSOR; GENOMIC DNA; GRANZYME B; INHIBITOR OF APOPTOSIS PROTEIN; LACTACYSTIN; LYSINE; PROCASPASE 3; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL VIABILITY; CONJUGATE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; UBIQUITINATION; WESTERN BLOTTING;

ACETYLCYSTEINE; APOPTOSIS; ARGININE; CASPASE 3; CASPASES; CELL LINE, TRANSFORMED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME PRECURSORS; HL-60 CELLS; HUMANS; LYSINE; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; PROTEINS; TRANSFECTION; UBIQUITIN; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 0041842553     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.2.334     Document Type: Article

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