-
2
-
-
78649389922
-
Nasopharyngeal carcinoma
-
Chan AT. Nasopharyngeal carcinoma. Ann. Oncol 2010;21 Suppl 7: vii308-12.
-
(2010)
Ann. Oncol
, vol.21
, Issue.SUPPL. 7
-
-
Chan, A.T.1
-
3
-
-
79955032392
-
Modern treatment for nasopharyngeal carcinoma: Current status and prospects
-
Rottey S, Madani I, Deron P, Van Belle S. Modern treatment for nasopharyngeal carcinoma: current status and prospects. Curr Opin Oncol 2011;23:254-8.
-
(2011)
Curr Opin Oncol
, vol.23
, pp. 254-258
-
-
Rottey, S.1
Madani, I.2
Deron, P.3
Van Belle, S.4
-
4
-
-
14544304586
-
Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: A pooled data analysis of two phase III trials
-
Chua DT,MaJ, ShamJS, Mai HQ, Choy DT, Hong MH, et al. Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: a pooled data analysis of two phase III trials. J Clin Oncol 2005;23:1118-24.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1118-1124
-
-
Dtmaj, C.1
Shamjs Mai, H.Q.2
Choy, D.T.3
Hong, M.H.4
-
5
-
-
78449250038
-
Current treatment options for recurrent nasopharyngeal cancer
-
Suarez C, Rodrigo JP, Rinaldo A, Langendijk JA, Shaha AR, Ferlito A. Current treatment options for recurrent nasopharyngeal cancer. Eur Arch Otorhinolaryngol 2010;267:1811-24.
-
(2010)
Eur Arch Otorhinolaryngol
, vol.267
, pp. 1811-1824
-
-
Suarez, C.1
Rodrigo, J.P.2
Rinaldo, A.3
Langendijk, J.A.4
Shaha, A.R.5
Ferlito, A.6
-
6
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by highthroughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, et al. Identification of selective inhibitors of cancer stem cells by highthroughput screening. Cell 2009;138:645-59.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
-
7
-
-
77956954455
-
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens
-
Smith KM, Datti A, Fujitani M, Grinshtein N, Zhang L, Morozova O, et al. Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens. EMBO Mol Med 2010;2:371-84.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 371-384
-
-
Smith, K.M.1
Datti, A.2
Fujitani, M.3
Grinshtein, N.4
Zhang, L.5
Morozova, O.6
-
8
-
-
77954218647
-
Potential therapeutic implications of cancer stem cells in glioblastoma
-
Cheng L, Bao S, Rich JN. Potential therapeutic implications of cancer stem cells in glioblastoma. Biochem Pharmacol 2010;80:654-65.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 654-665
-
-
Cheng, L.1
Bao, S.2
Rich, J.N.3
-
9
-
-
78649986150
-
TGF-βeta receptor inhibitors target the CD44(high)/ Id1(high) glioma-initiating cell population in human glioblastoma
-
Anido J, Saez-Borderias A, Gonzalez-Junca A, Rodon L, Folch G, Carmona MA, et al. TGF-βeta receptor inhibitors target the CD44(high)/ Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell 2010;18:655-68.
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
Rodon, L.4
Folch, G.5
Carmona, M.A.6
-
11
-
-
84856534355
-
Stem cell pathways contribute to clinical chemoresistance in ovarian cancer
-
Steg AD, Bevis KS, Katre AA, Ziebarth A, Alvarez RD, Zhang K, et al. Stem cell pathways contribute to clinical chemoresistance in ovarian cancer. Clin Cancer Res 2012;18:869-81.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 869-881
-
-
Steg, A.D.1
Bevis, K.S.2
Katre, A.A.3
Ziebarth, A.4
Alvarez, R.D.5
Zhang, K.6
-
12
-
-
64149101418
-
Tumor initiating cells in malignant gliomas: Biology and implications for therapy
-
Hadjipanayis CG, Van Meir EG. Tumor initiating cells in malignant gliomas: biology and implications for therapy. J Mol Med 2009;87: 363-74.
-
(2009)
J Mol Med
, vol.87
, pp. 363-374
-
-
Hadjipanayis, C.G.1
Van Meir, E.G.2
-
13
-
-
34248529666
-
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
-
Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 2007;67:3716-24.
-
(2007)
Cancer Res
, vol.67
, pp. 3716-3724
-
-
Wang, J.1
Guo, L.P.2
Chen, L.Z.3
Zeng, Y.X.4
Lu, S.H.5
-
14
-
-
78751552761
-
Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation
-
Lee TK, Castilho A, Cheung VC, Tang KH, Ma S, Ng IO. Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation. Hepatology 2011;53:160-70.
-
(2011)
Hepatology
, vol.53
, pp. 160-170
-
-
Lee, T.K.1
Castilho, A.2
Cheung, V.C.3
Tang, K.H.4
Ma, S.5
Ng, I.O.6
-
15
-
-
77951730125
-
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
-
Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, et al. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Cancer Res 2010;16:2580-90.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2580-2590
-
-
Li, Y.1
Zhang, T.2
Korkaya, H.3
Liu, S.4
Lee, H.F.5
Newman, B.6
-
16
-
-
84861995326
-
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
-
Sachlos E, Risueno RM, Laronde S, Shapovalova Z, Lee JH, Russell J, et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 2012;149:1284-97.
-
(2012)
Cell
, vol.149
, pp. 1284-1297
-
-
Sachlos, E.1
Risueno, R.M.2
Laronde, S.3
Shapovalova, Z.4
Lee, J.H.5
Russell, J.6
-
17
-
-
33745880104
-
Side population (SP) cells: Taking center stage in regeneration and liver cancer?
-
Forbes SJ, Alison MR. Side population (SP) cells: taking center stage in regeneration and liver cancer? Hepatology 2006;44:23-6.
-
(2006)
Hepatology
, vol.44
, pp. 23-26
-
-
Forbes, S.J.1
Alison, M.R.2
-
18
-
-
33744985294
-
Characterization of a side population of cancer cells from human gastrointestinal system
-
Haraguchi N, Utsunomiya T, Inoue H, Tanaka F, Mimori K, Barnard GF, et al. Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells 2006;24:506-13.
-
(2006)
Stem Cells
, vol.24
, pp. 506-513
-
-
Haraguchi, N.1
Utsunomiya, T.2
Inoue, H.3
Tanaka, F.4
Mimori, K.5
Barnard, G.F.6
-
19
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
20
-
-
70549113666
-
Apoptosis signaling in cancer stem cells
-
Fulda S, Pervaiz S. Apoptosis signaling in cancer stem cells. Int J Biochem Cell Biol 2010;42:31-8.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 31-38
-
-
Fulda, S.1
Pervaiz, S.2
-
21
-
-
79955591914
-
Recent advances in apoptosis mitochondria and drug resistance in cancer cells
-
Indran IR, Tufo G, Pervaiz S, Brenner C. Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochim Biophys Acta 2011;1807:735-45.
-
(2011)
Biochim Biophys Acta
, vol.1807
, pp. 735-745
-
-
Indran, I.R.1
Tufo, G.2
Pervaiz, S.3
Brenner, C.4
-
23
-
-
33645640920
-
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
-
Eckelman BP, Salvesen GS. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 2006; 281:3254-60.
-
(2006)
J Biol Chem
, vol.281
, pp. 3254-3260
-
-
Eckelman, B.P.1
Salvesen, G.S.2
-
24
-
-
77956692114
-
X-linked inhibitor of apoptosis: A chemoresistance factor or a hollow promise
-
Kashkar H. X-linked inhibitor of apoptosis: a chemoresistance factor or a hollow promise. Clin Cancer Res 2010;16:4496-502.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4496-4502
-
-
Kashkar, H.1
-
25
-
-
33749252583
-
Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family
-
Eckelman BP, Salvesen GS, Scott FL. Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family. EMBO Rep 2006;7:988-94.
-
(2006)
EMBO Rep
, vol.7
, pp. 988-994
-
-
Eckelman, B.P.1
Salvesen, G.S.2
Scott, F.L.3
-
26
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 2002;3:401-10.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
27
-
-
2342445559
-
Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells
-
Yang QH, Du C. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells. J Biol Chem 2004;279:16963-70.
-
(2004)
J Biol Chem
, vol.279
, pp. 16963-16970
-
-
Du Yang, Q.H.C.1
-
28
-
-
3843086358
-
Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondriaderived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site
-
Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, et al. Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondriaderived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site. J Med Chem 2004;47: 4147-50.
-
(2004)
J Med Chem
, vol.47
, pp. 4147-4150
-
-
Sun, H.1
Nikolovska-Coleska, Z.2
Yang, C.Y.3
Xu, L.4
Tomita, Y.5
Krajewski, K.6
-
29
-
-
33845919012
-
Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic
-
Sun H, Nikolovska-Coleska Z, Lu J, Qiu S, Yang CY, Gao W, et al. Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic. J Med Chem 2006;49: 7916-20.
-
(2006)
J Med Chem
, vol.49
, pp. 7916-7920
-
-
Sun, H.1
Nikolovska-Coleska, Z.2
Lu, J.3
Qiu, S.4
Yang, C.Y.5
Gao, W.6
-
30
-
-
37749037799
-
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs
-
Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, et al. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. ACS Chem Biol 2006;1:525-33.
-
(2006)
ACS Chem Biol
, vol.1
, pp. 525-533
-
-
Zobel, K.1
Wang, L.2
Varfolomeev, E.3
Franklin, M.C.4
Elliott, L.O.5
Wallweber, H.J.6
-
31
-
-
33846878524
-
Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)
-
Chauhan D, Neri P, Velankar M, Podar K, Hideshima T, Fulciniti M, et al. Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM). Blood 2007;109:1220-7.
-
(2007)
Blood
, vol.109
, pp. 1220-1227
-
-
Chauhan, D.1
Neri, P.2
Velankar, M.3
Podar, K.4
Hideshima, T.5
Fulciniti, M.6
-
32
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007;131:682-93.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
-
33
-
-
62449168519
-
TRAIL agonists on clinical trials for cancer therapy - The promises and the challenges
-
Bellail AC, Qi L, Mulligan P, Chhabra V, Hao C. TRAIL agonists on clinical trials for cancer therapy- the promises and the challenges. Rev Recent Clin Trials 2009;4:34-41.
-
(2009)
Rev Recent Clin Trials
, vol.4
, pp. 34-41
-
-
Bellail, A.C.1
Qi, L.2
Mulligan, P.3
Chhabra, V.4
Hao, C.5
-
34
-
-
34247897233
-
Targeting TRAIL agonistic receptors for cancer therapy
-
Carlo-Stella C, Lavazza C, Locatelli A, Vigano L, Gianni AM, Gianni L. Targeting TRAIL agonistic receptors for cancer therapy. Clin Cancer Res 2007;13:2313-7.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2313-2317
-
-
Carlo-Stella, C.1
Lavazza, C.2
Locatelli, A.3
Vigano, L.4
Gianni, A.M.5
Gianni, L.6
-
35
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
-
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 2004;305:1471-4.
-
(2004)
Science
, vol.305
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
36
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S, Wick W, Weller M, Debatin KM. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med 2002;8:808-15.
-
(2002)
Nat Med
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
Debatin, K.M.4
-
37
-
-
79956006296
-
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment
-
Lu J, McEachern D, Sun H, Bai L, Peng Y, Qiu S, et al. Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. Mol Cancer Ther 2011;10:902-14.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 902-914
-
-
Lu, J.1
McEachern, D.2
Sun, H.3
Bai, L.4
Peng, Y.5
Qiu, S.6
-
38
-
-
56449103218
-
SM-164: A novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP
-
Lu J, Bai L, Sun H, Nikolovska-Coleska Z, McEachern D, Qiu S, et al. SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP. Cancer Res 2008;68:9384-93.
-
(2008)
Cancer Res
, vol.68
, pp. 9384-9393
-
-
Lu, J.1
Bai, L.2
Sun, H.3
Nikolovska-Coleska, Z.4
McEachern, D.5
Qiu, S.6
-
39
-
-
33751275549
-
Preparing the "soil": The primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells
-
Qian CN, Berghuis B, Tsarfaty G, Bruch M, Kort EJ, Ditlev J, et al. Preparing the "soil": the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells. Cancer Res 2006;66:10365-76.
-
(2006)
Cancer Res
, vol.66
, pp. 10365-10376
-
-
Qian, C.N.1
Berghuis, B.2
Tsarfaty, G.3
Bruch, M.4
Kort, E.J.5
Ditlev, J.6
-
40
-
-
79954504195
-
A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment
-
Cai Q, Sun H, Peng Y, Lu J, Nikolovska-Coleska Z, McEachern D, et al. A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. J Med Chem 2011;54:2714-26.
-
(2011)
J Med Chem
, vol.54
, pp. 2714-2726
-
-
Cai, Q.1
Sun, H.2
Peng, Y.3
Lu, J.4
Nikolovska-Coleska, Z.5
McEachern, D.6
-
41
-
-
35948994157
-
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis
-
Petersen SL, Wang L, Yalcin-Chin A, Li L, Peyton M, Minna J, et al. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 2007;12:445-56.
-
(2007)
Cancer Cell
, vol.12
, pp. 445-456
-
-
Petersen, S.L.1
Wang, L.2
Yalcin-Chin, A.3
Li, L.4
Peyton, M.5
Minna, J.6
-
42
-
-
84863154799
-
Initial testing (stage 1) of LCL161, a SMAC mimetic, by the Pediatric Preclinical Testing Program
-
Houghton PJ, Kang MH, Reynolds CP, Morton CL, Kolb EA, Gorlick R, et al. Initial testing (stage 1) of LCL161, a SMAC mimetic, by the Pediatric Preclinical Testing Program. Pediatr Blood Cancer 2012; 58:636-9.
-
(2012)
Pediatr Blood Cancer
, vol.58
, pp. 636-639
-
-
Houghton, P.J.1
Kang, M.H.2
Reynolds, C.P.3
Morton, C.L.4
Kolb, E.A.5
Gorlick, R.6
-
43
-
-
0346792725
-
TRAIL and apoptosis induction by TNF-family death receptors
-
Wang S, El-Deiry WS. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 2003;22:8628-33.
-
(2003)
Oncogene
, vol.22
, pp. 8628-8633
-
-
Wang, S.1
El-Deiry, W.S.2
-
44
-
-
41049112098
-
TRAIL and cancer therapy
-
Kruyt FA. TRAIL and cancer therapy. Cancer Lett 2008;263:14-25.
-
(2008)
Cancer Lett
, vol.263
, pp. 14-25
-
-
Kruyt, F.A.1
-
45
-
-
77956414973
-
Phase i dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer
-
Herbst RS, Eckhardt SG, Kurzrock R, Ebbinghaus S, O'Dwyer PJ, Gordon MS, et al. Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer. J Clin Oncol 2010;28:2839-46.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2839-2846
-
-
Herbst, R.S.1
Eckhardt, S.G.2
Kurzrock, R.3
Ebbinghaus, S.4
O'Dwyer, P.J.5
Gordon, M.S.6
-
46
-
-
78549284338
-
Smacmimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells
-
Metwalli AR, Khanbolooki S, Jinesh G, Sundi D, Shah JB, Shrader M, et al. Smacmimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells. Cancer Biol Ther 2010;10:885-92.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 885-892
-
-
Metwalli, A.R.1
Khanbolooki, S.2
Jinesh, G.3
Sundi, D.4
Shah, J.B.5
Shrader, M.6
|