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Volumn 8, Issue 11, 2009, Pages 3140-3150

Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CASPASE; COLLAGEN TYPE 4; FIBRONECTIN; G 5; GLUTATHIONE; PROTEASOME INHIBITOR; PROTEIN MCL 1; PROTEIN NOXA; TENASCIN; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 70949102233     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0431     Document Type: Article
Times cited : (20)

References (41)
  • 2
    • 0036675901 scopus 로고    scopus 로고
    • The molecular and genetic basis of neurological tumours
    • DOI 10.1038/nrc866
    • Zhu Y, Parada LF. The molecular and genetic basis of neurological tumours. Nat Rev Cancer 2002;2:616-626 (Pubitemid 37328928)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.8 , pp. 616-626
    • Zhu, Y.1    Parada, L.F.2
  • 3
    • 33644824608 scopus 로고    scopus 로고
    • Altering protein turnover in tumor cells: New opportunities for anti-cancer therapies
    • DOI 10.1016/j.drup.2005.12.001, PII S1368764605001032
    • Demarchi F, Brancolini C. Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies. Drug Resist Updat 2005; 8:359-368 (Pubitemid 43358059)
    • (2005) Drug Resistance Updates , vol.8 , Issue.6 , pp. 359-368
    • Demarchi, F.1    Brancolini, C.2
  • 4
    • 67649752135 scopus 로고    scopus 로고
    • Inhibitors of the ubiquitin-proteasome system and the cell death machinery: How many pathways are activated?
    • Brancolini C. Inhibitors of the ubiquitin-proteasome system and the cell death machinery: how many pathways are activated? Curr Mol Pharm 2008;1:24-37.
    • (2008) Curr Mol Pharm , vol.1 , pp. 24-37
    • Brancolini, C.1
  • 5
    • 35348931646 scopus 로고    scopus 로고
    • Mechanisms, biology and inhibitors of deubiquitinating enzymes
    • DOI 10.1038/nchembio.2007.43, PII NCHEMBIO200743
    • Love KR, Catic A, Schlieker C, Ploegh HL. Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat Chem Biol 2007;3: 697-705. (Pubitemid 47609116)
    • (2007) Nature Chemical Biology , vol.3 , Issue.11 , pp. 697-705
    • Love, K.R.1    Catic, A.2    Schlieker, C.3    Ploegh, H.L.4
  • 6
    • 9644268864 scopus 로고    scopus 로고
    • Mechanism and function of deubiquitinating enzymes
    • Amerik AY, Hochstrasser M. Mechanism and function of deubiquitinating enzymes. Biochim. Biophys Acta 2004;1695:189-207.
    • (2004) Biochim. Biophys Acta , vol.1695 , pp. 189-207
    • Amerik, A.Y.1    Hochstrasser, M.2
  • 7
    • 33847705665 scopus 로고    scopus 로고
    • Role of ubiquitin- and Ubl-binding proteins in cell signaling
    • DOI 10.1016/j.ceb.2007.02.002, PII S0955067407000166
    • Kirkin V, Dikic I. Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr Opin Cell Biol 2007;19:199-205. (Pubitemid 46386400)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.2 , pp. 199-205
    • Kirkin, V.1    Dikic, I.2
  • 8
    • 33749482993 scopus 로고    scopus 로고
    • Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis
    • DOI 10.1158/0008-5472.CAN-06-0702
    • Aleo E, Henderson CJ, Fontanini A, Solazzo B, Brancolini C. Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res 2006;66:9235-9244 (Pubitemid 44521145)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9235-9244
    • Aleo, E.1    Henderson, C.J.2    Fontanini, A.3    Solazzo, B.4    Brancolini, C.5
  • 9
    • 0036070772 scopus 로고    scopus 로고
    • Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death
    • Mullally JE, Fitzpatrick FA. Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death. Mol Pharmacol 2002;62:351-358
    • (2002) Mol Pharmacol , vol.62 , pp. 351-358
    • Mullally, J.E.1    Fitzpatrick, F.A.2
  • 11
    • 66349117098 scopus 로고    scopus 로고
    • The isopeptidase inhibitor G5 triggers a caspase-independent necrotic death in cells resistant to apoptosis: A comparative study with the proteasome inhibitor bortezomib
    • Fontanini A, Foti C, Potu H, et al. The isopeptidase inhibitor G5 triggers a caspase-independent necrotic death in cells resistant to apoptosis: a comparative study with the proteasome inhibitor bortezomib. J Biol Chem 2009;284:8369-8381
    • (2009) J Biol Chem , vol.284 , pp. 8369-8381
    • Fontanini, A.1    Foti, C.2    Potu, H.3
  • 13
    • 51049112961 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis
    • Opel D, Westhoff MA, Bender A, Braun V, Debatin KM, Fulda S. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis. Cancer Res 2008; 68:6271-6280
    • (2008) Cancer Res , vol.68 , pp. 6271-6280
    • Opel, D.1    Westhoff, M.A.2    Bender, A.3    Braun, V.4    Debatin, K.M.5    Fulda, S.6
  • 14
    • 0242432345 scopus 로고    scopus 로고
    • Many cuts to ruin: A comprehensive update of caspase substrates
    • DOI 10.1038/sj.cdd.4401160
    • Fischer U, Janicke RU, Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ 2003; 10:76-100. (Pubitemid 36511834)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.1 , pp. 76-100
    • Fischer, U.1    Janicke, R.U.2    Schulze-Osthoff, K.3
  • 15
    • 37549042449 scopus 로고    scopus 로고
    • Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: P53 determines the switch by regulating xpc,dd b2, and DNA double-strand breaks
    • Batista LF, Roos WP, Christmann M, Menck CF, Kaina B. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc,dd b2, and DNA double-strand breaks. Cancer Res 2007;67:11886-11895
    • (2007) Cancer Res , vol.67 , pp. 11886-11895
    • Batista, L.F.1    Roos, W.P.2    Christmann, M.3    Menck, C.F.4    Kaina, B.5
  • 16
    • 40749111022 scopus 로고    scopus 로고
    • Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas
    • Li A, Walling J, Kotliarov Y, et al. Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas. Mol Cancer Res 2008;6:21-30.
    • (2008) Mol Cancer Res , vol.6 , pp. 21-30
    • Li, A.1    Walling, J.2    Kotliarov, Y.3
  • 17
    • 0026683968 scopus 로고
    • Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas
    • Olopade OI, Jenkins RB, Ransom DT, et al. Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas. Cancer Res 1992;52:2523-2529
    • (1992) Cancer Res , vol.52 , pp. 2523-2529
    • Olopade, O.I.1    Jenkins, R.B.2    Ransom, D.T.3
  • 19
    • 4644303022 scopus 로고    scopus 로고
    • Human glutamate cysteine ligase gene regulation through the electrophile response element
    • Dickinson DA, Levonen AL, Moellering DR, et al. Human glutamate cysteine ligase gene regulation through the electrophile response element. Free Radic Biol Med 2004;37:1152-1159
    • (2004) Free Radic Biol Med , vol.37 , pp. 1152-1159
    • Dickinson, D.A.1    Levonen, A.L.2    Moellering, D.R.3
  • 20
    • 0035861744 scopus 로고    scopus 로고
    • Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U- 937 human promonocytic cells. The role of intracellular oxidation
    • Troyano A, Fernández C, Sancho P, De Blas E, Aller P. Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U- 937 human promonocytic cells. The role of intracellular oxidation. J Biol Chem 2001;276:47107-47115
    • (2001) J Biol Chem , vol.276 , pp. 47107-47115
    • Troyano, A.1    Fernández, C.2    Sancho, P.3    De Blas, E.4    Aller, P.5
  • 21
    • 4644364745 scopus 로고    scopus 로고
    • Effect of curcumin on normal and tumor cells: Role of glutathione and bcl-2
    • Syng-Ai C, Kumari AL, Khar A. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol Cancer Ther 2004;3:1101-1108 (Pubitemid 39295007)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.9 , pp. 1101-1108
    • Syng-Ai, C.1    Kumari, A.L.2    Khar, A.3
  • 22
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith OW, Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem 1979;254:7558-7560 (Pubitemid 10230219)
    • (1979) Journal of Biological Chemistry , vol.254 , Issue.16 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 23
    • 33644976378 scopus 로고    scopus 로고
    • GSH depletion, protein S-glutathionylation and mitochondrial transmembrane potential hyperpolarization are early events in initiation of cell death induced by a mixture of isothiazolinones in HL60 cells
    • Di Stefano A, Frosali S, Leonini A, et al. GSH depletion, protein S-glutathionylation and mitochondrial transmembrane potential hyperpolarization are early events in initiation of cell death induced by a mixture of isothiazolinones in HL60 cells. Biochim Biophys Acta 2006;1763:214-225
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 214-225
    • Di Stefano, A.1    Frosali, S.2    Leonini, A.3
  • 26
    • 33846018602 scopus 로고    scopus 로고
    • Cell death by necrosis: Towards a molecular definition
    • DOI 10.1016/j.tibs.2006.11.001, PII S0968000406003185
    • Golstein P, Kroemer G. Cell death by necrosis: towards a molecular definition. Trends Biochem Sci 2007;32:37-43. (Pubitemid 46043552)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.1 , pp. 37-43
    • Golstein, P.1    Kroemer, G.2
  • 27
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • Zong WX, Thompson CB. Necrotic death as a cell fate. Genes Dev 2006;20:1-15.
    • (2006) Genes Dev , vol.20 , pp. 1-15
    • Zong, W.X.1    Thompson, C.B.2
  • 28
    • 57649181391 scopus 로고    scopus 로고
    • Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
    • Hitomi J, Christofferson DE, Ng A, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008;135:1311-1323
    • (2008) Cell , vol.135 , pp. 1311-1323
    • Hitomi, J.1    Christofferson, D.E.2    Ng, A.3
  • 29
    • 13244262655 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM)
    • DOI 10.1038/sj.onc.1208225
    • Yin D, Zhou H, Kumagai T, et al. Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM). Oncogene 2005;24:344-354 (Pubitemid 40188583)
    • (2005) Oncogene , vol.24 , Issue.3 , pp. 344-354
    • Yin, D.1    Zhou, H.2    Kumagai, T.3    Liu, G.4    Ong, J.M.5    Black, K.L.6    Koeffler, H.P.7
  • 30
    • 33846491404 scopus 로고    scopus 로고
    • NF-κB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition
    • DOI 10.1038/sj.onc.1209841, PII 1209841
    • La Ferla-Bruhl K, Westhoff MA, Karl S, et al. NF-kB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. Oncogene 2007;26:571-582 (Pubitemid 46160970)
    • (2007) Oncogene , vol.26 , Issue.4 , pp. 571-582
    • La Ferla-Bruhl, K.1    Westhoff, M.A.2    Karl, S.3    Kasperczyk, H.4    Zwacka, R.M.5    Debatin, K.M.6    Fulda, S.7
  • 31
    • 0027990215 scopus 로고
    • Apoptosis or necrosis: Intracellular levels of glutathione influence the mode of cell death
    • Fernandes RS, Cotter TG. Apoptosis or necrosis: intracellular levels of glutathione influence the mode of cell death. Biochem. Pharmacol 1994; 48:675-681
    • (1994) Biochem. Pharmacol , vol.48 , pp. 675-681
    • Fernandes, R.S.1    Cotter, T.G.2
  • 32
    • 33845794791 scopus 로고    scopus 로고
    • 2-terminal kinase and up-regulation of death receptors
    • DOI 10.1158/0008-5472.CAN-06-0409
    • Chen D, Chan R, Waxman S, Jing Y. Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors. Cancer Res 2006;66:11416-11423 (Pubitemid 46009973)
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11416-11423
    • Chen, D.1    Chan, R.2    Waxman, S.3    Jing, Y.4
  • 33
    • 60849086193 scopus 로고    scopus 로고
    • Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas
    • Anathy V, Aesif SW, Guala AS, et al. Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas. J Cell Biol 2009;184:241-252
    • (2009) J Cell Biol , vol.184 , pp. 241-252
    • Anathy, V.1    Aesif, S.W.2    Guala, A.S.3
  • 39
    • 0035576810 scopus 로고    scopus 로고
    • Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation
    • Huang W, Chiquet-Ehrismann R, Moyano JV, Garcia-Pardo A, Orend G. Interference of tenascin-C with syndecan-4 binding to fibronectin blocks cell adhesion and stimulates tumor cell proliferation. Cancer Res 2001;61:8586-8594 (Pubitemid 33131143)
    • (2001) Cancer Research , vol.61 , Issue.23 , pp. 8586-8594
    • Huang, W.1    Chiquet-Ehrismann, R.2    Moyano, J.V.3    Garcia-Pardo, A.4    Orend, G.5
  • 40
    • 34247242084 scopus 로고    scopus 로고
    • Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision
    • Belkaid A, Fortier S, Cao J, Borhane A. Necrosis induction in glioblastoma cells reveals a new "bioswitch" function for the MT1-MMP/G6PT signaling axis in proMMP-2 activation versus cell death decision. Neoplasia 2007;9:332-340
    • (2007) Neoplasia , vol.9 , pp. 332-340
    • Belkaid, A.1    Fortier, S.2    Cao, J.3    Borhane, A.4
  • 41
    • 71849119209 scopus 로고    scopus 로고
    • The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal
    • Chaigne-Delalande B, Guidicelli G, Couzi L, et al. The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal. J Immunol 2008;181:7630-7638
    • (2008) J Immunol , vol.181 , pp. 7630-7638
    • Chaigne-Delalande, B.1    Guidicelli, G.2    Couzi, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.