-
1
-
-
42949123365
-
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
-
Sanacora G., Zarate C.A., Krystal J.H., Manji H.K. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov 2008, 7:426-437.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 426-437
-
-
Sanacora, G.1
Zarate, C.A.2
Krystal, J.H.3
Manji, H.K.4
-
2
-
-
0036370601
-
Prolonged effect of an anesthetic dose of ketamine on behavioral despair
-
Yilmaz A., Schulz D., Aksoy A., Canbeyli R. Prolonged effect of an anesthetic dose of ketamine on behavioral despair. Pharmacol Biochem Behav 2002, 71:341-344.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 341-344
-
-
Yilmaz, A.1
Schulz, D.2
Aksoy, A.3
Canbeyli, R.4
-
3
-
-
84891684419
-
Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR
-
Akinfiresoye L., Tizabi Y. Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR. Psychopharmacology (Berl) 2013, 230:291-298.
-
(2013)
Psychopharmacology (Berl)
, vol.230
, pp. 291-298
-
-
Akinfiresoye, L.1
Tizabi, Y.2
-
4
-
-
79960057257
-
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
-
Autry A.E., Adachi M., Nosyreva E., Na E.S., Los M.F., Cheng P.F., et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 2011, 475:91-95.
-
(2011)
Nature
, vol.475
, pp. 91-95
-
-
Autry, A.E.1
Adachi, M.2
Nosyreva, E.3
Na, E.S.4
Los, M.F.5
Cheng, P.F.6
-
5
-
-
84879242876
-
Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism
-
Gigliucci V., O'Dowd G., Casey S., Egan D., Gibney S., Harkin A. Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism. Psychopharmacology (Berl) 2013, 228:157-166.
-
(2013)
Psychopharmacology (Berl)
, vol.228
, pp. 157-166
-
-
Gigliucci, V.1
O'Dowd, G.2
Casey, S.3
Egan, D.4
Gibney, S.5
Harkin, A.6
-
6
-
-
79959350106
-
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression
-
Koike H., Iijima M., Chaki S. Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression. Behav Brain Res 2011, 224:107-111.
-
(2011)
Behav Brain Res
, vol.224
, pp. 107-111
-
-
Koike, H.1
Iijima, M.2
Chaki, S.3
-
7
-
-
38349186799
-
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors
-
Maeng S., Zarate C.A., Du J., Schloesser R.J., McCammon J., Chen G., et al. Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biol Psychiatry 2008, 63:349-352.
-
(2008)
Biol Psychiatry
, vol.63
, pp. 349-352
-
-
Maeng, S.1
Zarate, C.A.2
Du, J.3
Schloesser, R.J.4
McCammon, J.5
Chen, G.6
-
8
-
-
84886722040
-
Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats
-
Parise E.M., Alcantara L.F., Warren B.L., Wright K.N., Hadad R., Sial O.K., et al. Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats. Biol Psychiatry 2013, 74:750-759.
-
(2013)
Biol Psychiatry
, vol.74
, pp. 750-759
-
-
Parise, E.M.1
Alcantara, L.F.2
Warren, B.L.3
Wright, K.N.4
Hadad, R.5
Sial, O.K.6
-
9
-
-
79953166373
-
Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
-
Li N., Liu R.J., Dwyer J.M., Banasr M., Lee B., Son H., et al. Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry 2011, 69:754-761.
-
(2011)
Biol Psychiatry
, vol.69
, pp. 754-761
-
-
Li, N.1
Liu, R.J.2
Dwyer, J.M.3
Banasr, M.4
Lee, B.5
Son, H.6
-
10
-
-
84857083262
-
Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex
-
Liu R.J., Lee F.S., Li X.Y., Bambico F., Duman R.S., Aghajanian G.K. Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biol Psychiatry 2012, 71:996-1005.
-
(2012)
Biol Psychiatry
, vol.71
, pp. 996-1005
-
-
Liu, R.J.1
Lee, F.S.2
Li, X.Y.3
Bambico, F.4
Duman, R.S.5
Aghajanian, G.K.6
-
11
-
-
84884288609
-
GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine
-
Liu R.J., Fuchikami M., Dwyer J.M., Lepack A.E., Duman R.S., Aghajanian G.K. GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology 2013, 38:2268-2277.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 2268-2277
-
-
Liu, R.J.1
Fuchikami, M.2
Dwyer, J.M.3
Lepack, A.E.4
Duman, R.S.5
Aghajanian, G.K.6
-
12
-
-
79960213948
-
CD-1 and Balb/cJ mice do not show enduring antidepressant-like effects of ketamine in tests of acute antidepressant efficacy
-
Bechtholt-Gompf A.J., Smith K.L., John C.S., Kang H.H., Carlezon W.A., Cohen B.M., et al. CD-1 and Balb/cJ mice do not show enduring antidepressant-like effects of ketamine in tests of acute antidepressant efficacy. Psychopharmacology (Berl) 2011, 215:689-695.
-
(2011)
Psychopharmacology (Berl)
, vol.215
, pp. 689-695
-
-
Bechtholt-Gompf, A.J.1
Smith, K.L.2
John, C.S.3
Kang, H.H.4
Carlezon, W.A.5
Cohen, B.M.6
-
13
-
-
84920270347
-
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine
-
Miller O.H., Yang L., Wang C.C., Hargroder E.A., Zhang Y., Delpire E., et al. GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine. Elife 2014, 3.
-
(2014)
Elife
, pp. 3
-
-
Miller, O.H.1
Yang, L.2
Wang, C.C.3
Hargroder, E.A.4
Zhang, Y.5
Delpire, E.6
-
14
-
-
84861093240
-
(1)H-[(1)(3)C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism
-
Chowdhury G.M., Behar K.L., Cho W., Thomas M.A., Rothman D.L., Sanacora G. (1)H-[(1)(3)C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism. Biol Psychiatry 2012, 71:1022-1025.
-
(2012)
Biol Psychiatry
, vol.71
, pp. 1022-1025
-
-
Chowdhury, G.M.1
Behar, K.L.2
Cho, W.3
Thomas, M.A.4
Rothman, D.L.5
Sanacora, G.6
-
15
-
-
0030900732
-
Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
-
Moghaddam B., Adams B., Verma A., Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 1997, 17:2921-2927.
-
(1997)
J Neurosci
, vol.17
, pp. 2921-2927
-
-
Moghaddam, B.1
Adams, B.2
Verma, A.3
Daly, D.4
-
16
-
-
35548991088
-
NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons
-
Homayoun H., Moghaddam B. NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J Neurosci 2007, 27:11496-11500.
-
(2007)
J Neurosci
, vol.27
, pp. 11496-11500
-
-
Homayoun, H.1
Moghaddam, B.2
-
17
-
-
84900562296
-
Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits
-
Billingslea E.N., Tatard-Leitman V.M., Anguiano J., Jutzeler C.R., Suh J., Saunders J.A., et al. Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology 2014, 39:1603-1613.
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 1603-1613
-
-
Billingslea, E.N.1
Tatard-Leitman, V.M.2
Anguiano, J.3
Jutzeler, C.R.4
Suh, J.5
Saunders, J.A.6
-
18
-
-
33746902947
-
Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice
-
Boyce-Rustay J.M., Holmes A. Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice. Neuropsychopharmacology 2006, 31:2405-2414.
-
(2006)
Neuropsychopharmacology
, vol.31
, pp. 2405-2414
-
-
Boyce-Rustay, J.M.1
Holmes, A.2
-
19
-
-
79956116531
-
2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity
-
Brown D.G., Maier D.L., Sylvester M.A., Hoerter T.N., Menhaji-Klotz E., Lasota C.C., et al. 2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity. Bioorg Med Chem Lett 2011, 21:3399-3403.
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 3399-3403
-
-
Brown, D.G.1
Maier, D.L.2
Sylvester, M.A.3
Hoerter, T.N.4
Menhaji-Klotz, E.5
Lasota, C.C.6
-
20
-
-
80052440262
-
Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm
-
Kiselycznyk C., Svenningsson P., Delpire E., Holmes A. Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm. Neuroscience 2011, 193:259-268.
-
(2011)
Neuroscience
, vol.193
, pp. 259-268
-
-
Kiselycznyk, C.1
Svenningsson, P.2
Delpire, E.3
Holmes, A.4
-
21
-
-
84878356520
-
Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain
-
Lima-Ojeda J.M., Vogt M.A., Pfeiffer N., Dormann C., Kohr G., Sprengel R., et al. Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain. Prog Neuropsychopharmacol Biol Psychiatry 2013, 45:28-33.
-
(2013)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.45
, pp. 28-33
-
-
Lima-Ojeda, J.M.1
Vogt, M.A.2
Pfeiffer, N.3
Dormann, C.4
Kohr, G.5
Sprengel, R.6
-
22
-
-
84880361652
-
Effects of ifenprodil on the antidepressant-like activity of NMDA ligands in the forced swim test in mice
-
Poleszak E., Wosko S., Serefko A., Szopa A., Wlaz A., Szewczyk B., et al. Effects of ifenprodil on the antidepressant-like activity of NMDA ligands in the forced swim test in mice. Prog Neuropsychopharmacol Biol Psychiatry 2013, 46:29-35.
-
(2013)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.46
, pp. 29-35
-
-
Poleszak, E.1
Wosko, S.2
Serefko, A.3
Szopa, A.4
Wlaz, A.5
Szewczyk, B.6
-
23
-
-
77955909841
-
MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
-
Li N., Lee B., Liu R.J., Banasr M., Dwyer J.M., Iwata M., et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010, 329:959-964.
-
(2010)
Science
, vol.329
, pp. 959-964
-
-
Li, N.1
Lee, B.2
Liu, R.J.3
Banasr, M.4
Dwyer, J.M.5
Iwata, M.6
-
24
-
-
59049098262
-
An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-d-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder
-
Preskorn S.H., Baker B., Kolluri S., Menniti F.S., Krams M., Landen J.W. An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-d-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. J Clin Psychopharmacol 2008, 28:631-637.
-
(2008)
J Clin Psychopharmacol
, vol.28
, pp. 631-637
-
-
Preskorn, S.H.1
Baker, B.2
Kolluri, S.3
Menniti, F.S.4
Krams, M.5
Landen, J.W.6
-
25
-
-
84896311638
-
Mice lacking NMDA receptors in parvalbumin neurons display normal depression-related behavior and response to antidepressant action of NMDAR antagonists
-
Pozzi L., Dorocic I.P., Wang X., Carlen M., Meletis K. Mice lacking NMDA receptors in parvalbumin neurons display normal depression-related behavior and response to antidepressant action of NMDAR antagonists. PLOS ONE 2014, 9:e83879.
-
(2014)
PLOS ONE
, vol.9
, pp. e83879
-
-
Pozzi, L.1
Dorocic, I.P.2
Wang, X.3
Carlen, M.4
Meletis, K.5
-
26
-
-
73949136265
-
Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
-
Belforte J.E., Zsiros V., Sklar E.R., Jiang Z., Yu G., Li Y., et al. Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat Neurosci 2010, 13:76-83.
-
(2010)
Nat Neurosci
, vol.13
, pp. 76-83
-
-
Belforte, J.E.1
Zsiros, V.2
Sklar, E.R.3
Jiang, Z.4
Yu, G.5
Li, Y.6
-
27
-
-
84861692754
-
Antidepressant-like effects of low ketamine dose is associated with increased hippocampal AMPA/NMDA receptor density ratio in female Wistar-Kyoto rats
-
Tizabi Y., Bhatti B.H., Manaye K.F., Das J.R., Akinfiresoye L. Antidepressant-like effects of low ketamine dose is associated with increased hippocampal AMPA/NMDA receptor density ratio in female Wistar-Kyoto rats. Neuroscience 2013, 213:72-80.
-
(2013)
Neuroscience
, vol.213
, pp. 72-80
-
-
Tizabi, Y.1
Bhatti, B.H.2
Manaye, K.F.3
Das, J.R.4
Akinfiresoye, L.5
-
28
-
-
84867227874
-
Synaptic dysfunction in depression: potential therapeutic targets
-
Duman R.S., Aghajanian G.K. Synaptic dysfunction in depression: potential therapeutic targets. Science 2012, 338:68-72.
-
(2012)
Science
, vol.338
, pp. 68-72
-
-
Duman, R.S.1
Aghajanian, G.K.2
-
29
-
-
77957762046
-
Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?
-
Fitzgerald P.J., Barkus C., Feyder M., Wiedholz L.M., Chen Y.C., Karlsson R.M., et al. Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder?. Neurobiol Dis 2010, 40:608-621.
-
(2010)
Neurobiol Dis
, vol.40
, pp. 608-621
-
-
Fitzgerald, P.J.1
Barkus, C.2
Feyder, M.3
Wiedholz, L.M.4
Chen, Y.C.5
Karlsson, R.M.6
-
30
-
-
84873567426
-
GluA1 and its PDZ-interaction: a role in experience-dependent behavioral plasticity in the forced swim test
-
Freudenberg F., Marx V., Mack V., Layer L.E., Klugmann M., Seeburg P.H., et al. GluA1 and its PDZ-interaction: a role in experience-dependent behavioral plasticity in the forced swim test. Neurobiol Dis 2013, 52:160-167.
-
(2013)
Neurobiol Dis
, vol.52
, pp. 160-167
-
-
Freudenberg, F.1
Marx, V.2
Mack, V.3
Layer, L.E.4
Klugmann, M.5
Seeburg, P.H.6
-
31
-
-
84880331865
-
NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice
-
Walker A.K., Budac D.P., Bisulco S., Lee A.W., Smith R.A., Beenders B., et al. NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice. Neuropsychopharmacology 2013, 38:1609-1616.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1609-1616
-
-
Walker, A.K.1
Budac, D.P.2
Bisulco, S.3
Lee, A.W.4
Smith, R.A.5
Beenders, B.6
-
32
-
-
26044460006
-
The ascent of mouse: advances in modelling human depression and anxiety
-
Cryan J.F., Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 2005, 4:775-790.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 775-790
-
-
Cryan, J.F.1
Holmes, A.2
-
33
-
-
0017618768
-
Depression: a new animal model sensitive to antidepressant treatments
-
Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 1977, 266:730-732.
-
(1977)
Nature
, vol.266
, pp. 730-732
-
-
Porsolt, R.D.1
Le Pichon, M.2
Jalfre, M.3
-
34
-
-
39349087613
-
Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit
-
Brigman J.L., Feyder M., Saksida L.M., Bussey T.J., Mishina M., Holmes A. Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit. Learn Mem 2008, 15:50-54.
-
(2008)
Learn Mem
, vol.15
, pp. 50-54
-
-
Brigman, J.L.1
Feyder, M.2
Saksida, L.M.3
Bussey, T.J.4
Mishina, M.5
Holmes, A.6
-
35
-
-
84873316155
-
Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR Glycine co-agonist site
-
Debrouse L., Hurd B., Kiselycznyk C., Plitt A., Todaro A., Mishina M., et al. Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR Glycine co-agonist site. Alcohol Clin Exp Res 2013, 37:223-233.
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. 223-233
-
-
Debrouse, L.1
Hurd, B.2
Kiselycznyk, C.3
Plitt, A.4
Todaro, A.5
Mishina, M.6
-
36
-
-
77951008812
-
Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability
-
Mozhui K., Karlsson R.M., Kash T.L., Ihne J., Norcross M., Patel S., et al. Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability. J Neurosci 2010, 30:5357-5367.
-
(2010)
J Neurosci
, vol.30
, pp. 5357-5367
-
-
Mozhui, K.1
Karlsson, R.M.2
Kash, T.L.3
Ihne, J.4
Norcross, M.5
Patel, S.6
-
37
-
-
0028813106
-
Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit
-
Sakimura K., Kutsuwada T., Ito I., Manabe T., Takayama C., Kushiya E., et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 1995, 373:151-155.
-
(1995)
Nature
, vol.373
, pp. 151-155
-
-
Sakimura, K.1
Kutsuwada, T.2
Ito, I.3
Manabe, T.4
Takayama, C.5
Kushiya, E.6
-
38
-
-
48749132945
-
Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication
-
Palachick B., Chen Y.C., Enoch A.J., Karlsson R.M., Mishina M., Holmes A. Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication. Alcohol Clin Exp Res 2008, 32:1479-1492.
-
(2008)
Alcohol Clin Exp Res
, vol.32
, pp. 1479-1492
-
-
Palachick, B.1
Chen, Y.C.2
Enoch, A.J.3
Karlsson, R.M.4
Mishina, M.5
Holmes, A.6
-
39
-
-
84856093776
-
Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?
-
Barkus C., Feyder M., Graybeal C., Wright T., Wiedholz L., Izquierdo A., et al. Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?. Neuropharmacology 2012, 62:1263-1272.
-
(2012)
Neuropharmacology
, vol.62
, pp. 1263-1272
-
-
Barkus, C.1
Feyder, M.2
Graybeal, C.3
Wright, T.4
Wiedholz, L.5
Izquierdo, A.6
-
40
-
-
84901985938
-
Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors
-
Feyder M., Wiedholz L., Sprengel R., Holmes A. Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors. Front Behav Neurosci 2007, 1:4.
-
(2007)
Front Behav Neurosci
, vol.1
, pp. 4
-
-
Feyder, M.1
Wiedholz, L.2
Sprengel, R.3
Holmes, A.4
-
41
-
-
43949112985
-
Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors
-
Wiedholz L.M., Owens W.A., Horton R.E., Feyder M., Karlsson R.M., Hefner K., et al. Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors. Mol Psychiatry 2008, 13:631-640.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 631-640
-
-
Wiedholz, L.M.1
Owens, W.A.2
Horton, R.E.3
Feyder, M.4
Karlsson, R.M.5
Hefner, K.6
-
42
-
-
0033546059
-
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning
-
Zamanillo D., Sprengel R., Hvalby O., Jensen V., Burnashev N., Rozov A., et al. Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science 1999, 284:1805-1811.
-
(1999)
Science
, vol.284
, pp. 1805-1811
-
-
Zamanillo, D.1
Sprengel, R.2
Hvalby, O.3
Jensen, V.4
Burnashev, N.5
Rozov, A.6
-
43
-
-
79959825736
-
A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference
-
Camp M.C., Feyder M., Ihne J., Palachick B., Hurd B., Karlsson R.M., et al. A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference. Addict Biol 2011, 16:428-439.
-
(2011)
Addict Biol
, vol.16
, pp. 428-439
-
-
Camp, M.C.1
Feyder, M.2
Ihne, J.3
Palachick, B.4
Hurd, B.5
Karlsson, R.M.6
-
44
-
-
84922986593
-
Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95
-
Daut R.A., Busch E.F., Ihne J., Fisher D., Mishina M., Grant S.G., et al. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95. Addict Biol 2014, 20:259-262.
-
(2014)
Addict Biol
, vol.20
, pp. 259-262
-
-
Daut, R.A.1
Busch, E.F.2
Ihne, J.3
Fisher, D.4
Mishina, M.5
Grant, S.G.6
-
45
-
-
84932198519
-
Durable fear memories require PSD-95
-
(in press)
-
Fitzgerald P.F., Pinard C.R., Camp M.C., Feyder M., Sah A., Bergstrom H.C., et al. Durable fear memories require PSD-95. Mol Psychiatry 2014, (in press).
-
(2014)
Mol Psychiatry
-
-
Fitzgerald, P.F.1
Pinard, C.R.2
Camp, M.C.3
Feyder, M.4
Sah, A.5
Bergstrom, H.C.6
-
46
-
-
51749119227
-
Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning
-
Yang R.J., Mozhui K., Karlsson R.M., Cameron H.A., Williams R.W., Holmes A. Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning. Neuropsychopharmacology 2008, 33:2595-2604.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2595-2604
-
-
Yang, R.J.1
Mozhui, K.2
Karlsson, R.M.3
Cameron, H.A.4
Williams, R.W.5
Holmes, A.6
-
47
-
-
36348958594
-
The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice
-
Karlsson R.M., Choe J.S., Cameron H.A., Thorsell A., Crawley J.N., Holmes A., et al. The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology (Berl) 2008, 195:547-557.
-
(2008)
Psychopharmacology (Berl)
, vol.195
, pp. 547-557
-
-
Karlsson, R.M.1
Choe, J.S.2
Cameron, H.A.3
Thorsell, A.4
Crawley, J.N.5
Holmes, A.6
-
48
-
-
82255192187
-
Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF
-
Graybeal C., Feyder M., Schulman E., Saksida L.M., Bussey T.J., Brigman J.L., et al. Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF. Nat Neurosci 2011, 14:1507-1509.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1507-1509
-
-
Graybeal, C.1
Feyder, M.2
Schulman, E.3
Saksida, L.M.4
Bussey, T.J.5
Brigman, J.L.6
-
49
-
-
84866732155
-
Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding
-
Holmes A., Fitzgerald P.J., Macpherson K.P., Debrouse L., Colacicco G., Flynn S.M., et al. Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nat Neurosci 2012, 15:1359-1361.
-
(2012)
Nat Neurosci
, vol.15
, pp. 1359-1361
-
-
Holmes, A.1
Fitzgerald, P.J.2
Macpherson, K.P.3
Debrouse, L.4
Colacicco, G.5
Flynn, S.M.6
-
50
-
-
84879412059
-
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
-
Gunduz-Cinar O., Macpherson K.P., Cinar R., Gamble-George J., Sugden K., Williams B., et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. Mol Psychiatry 2013, 18:813-823.
-
(2013)
Mol Psychiatry
, vol.18
, pp. 813-823
-
-
Gunduz-Cinar, O.1
Macpherson, K.P.2
Cinar, R.3
Gamble-George, J.4
Sugden, K.5
Williams, B.6
-
51
-
-
24644506107
-
Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory
-
Zhao M.G., Toyoda H., Lee Y.S., Wu L.J., Ko S.W., Zhang X.H., et al. Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory. Neuron 2005, 47:859-872.
-
(2005)
Neuron
, vol.47
, pp. 859-872
-
-
Zhao, M.G.1
Toyoda, H.2
Lee, Y.S.3
Wu, L.J.4
Ko, S.W.5
Zhang, X.H.6
-
52
-
-
33846408289
-
Effects of Mild Early Life Stress on Abnormal Emotion-related Behaviors in 5-HTT Knockout Mice
-
Carroll J.C., Boyce-Rustay J.M., Millstein R., Yang R., Wiedholz L.M., Murphy D.L., et al. Effects of Mild Early Life Stress on Abnormal Emotion-related Behaviors in 5-HTT Knockout Mice. Behav Genet 2007, 37:214-222.
-
(2007)
Behav Genet
, vol.37
, pp. 214-222
-
-
Carroll, J.C.1
Boyce-Rustay, J.M.2
Millstein, R.3
Yang, R.4
Wiedholz, L.M.5
Murphy, D.L.6
-
53
-
-
80054116593
-
Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice
-
Ihne J.L., Fitzgerald P.J., Hefner K.R., Holmes A. Pharmacological modulation of stress-induced behavioral changes in the light/dark exploration test in male C57BL/6J mice. Neuropharmacology 2012, 62:464-473.
-
(2012)
Neuropharmacology
, vol.62
, pp. 464-473
-
-
Ihne, J.L.1
Fitzgerald, P.J.2
Hefner, K.R.3
Holmes, A.4
-
54
-
-
84860122481
-
A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
-
Carlen M., Meletis K., Siegle J.H., Cardin J.A., Futai K., Vierling-Claassen D., et al. A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior. Mol Psychiatry 2012, 17:537-548.
-
(2012)
Mol Psychiatry
, vol.17
, pp. 537-548
-
-
Carlen, M.1
Meletis, K.2
Siegle, J.H.3
Cardin, J.A.4
Futai, K.5
Vierling-Claassen, D.6
-
55
-
-
67349124358
-
Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models
-
Engin E., Treit D., Dickson C.T. Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models. Neuroscience 2009, 161:359-369.
-
(2009)
Neuroscience
, vol.161
, pp. 359-369
-
-
Engin, E.1
Treit, D.2
Dickson, C.T.3
-
56
-
-
79952985754
-
NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine
-
Haller J., Nagy R., Toth M., Pelczer K.G., Mikics E. NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine. Behav Pharmacol 2011, 22:113-121.
-
(2011)
Behav Pharmacol
, vol.22
, pp. 113-121
-
-
Haller, J.1
Nagy, R.2
Toth, M.3
Pelczer, K.G.4
Mikics, E.5
-
57
-
-
57449089957
-
Fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: Attenuation with ageing
-
Mathur P., Graybeal C., Feyder M., Davis M.I., Holmes A. Fear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: Attenuation with ageing. Pharmacol Biochem Behav 2009, 91:453-460.
-
(2009)
Pharmacol Biochem Behav
, vol.91
, pp. 453-460
-
-
Mathur, P.1
Graybeal, C.2
Feyder, M.3
Davis, M.I.4
Holmes, A.5
-
58
-
-
84879414896
-
Small-molecule inhibitors at the PSD-95/nNOS interface have antidepressant-like properties in mice
-
Doucet M.V., Levine H., Dev K.K., Harkin A. Small-molecule inhibitors at the PSD-95/nNOS interface have antidepressant-like properties in mice. Neuropsychopharmacology 2013, 38:1575-1584.
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1575-1584
-
-
Doucet, M.V.1
Levine, H.2
Dev, K.K.3
Harkin, A.4
|