Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism

Psychopharmacology

Volumn 228, Issue 1, 2013, Pages 157-166

  Gigliucci, Valentina ^a   O'Dowd, Grainne ^a   Casey, Sheena ^a   Egan, Danielle ^a   Gibney, Sinead ^a   Harkin, Andrew ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Antidepressant; Behaviour; Depression; Forced swimming test; Ketamine; NMDA receptor; Serotonin

Indexed keywords

KETAMINE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; FORCED SWIMMING TEST; FRONTAL CORTEX; IMMOBILIZATION STRESS; LOCOMOTION; MALE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; SEROTONIN BRAIN LEVEL;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID ANTAGONISTS; KETAMINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; STRESS, PSYCHOLOGICAL; SWIMMING; TIME FACTORS;

EID: 84879242876     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3024-x     Document Type: Article

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