Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory

Neuron

Volumn 47, Issue 6, 2005, Pages 859-872

  Zhao, Ming Gao ^a,b   Toyoda, Hiroki ^b   Lee, Yong Seok ^b,c   Wu, Long Jun ^a,b   Ko, Shanelle W ^b   Zhang, Xue Han ^a   Jia, Yongheng ^b   Shum, Fanny ^b   Xu, Hui ^b   Li, Bao Ming ^a   Kaang, Bong Kiun ^b,c   Zhuo, Min ^a,b  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF TORONTO   (Canada)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CINGULATE GYRUS; CONTROLLED STUDY; LONG TERM POTENTIATION; MALE; MEMORY; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EGTAZIC ACID; ELECTRIC STIMULATION; ELECTROPORATION; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEAR; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MEMORY; MICE; MICE, INBRED C57BL; PATCH-CLAMP TECHNIQUES; PHENOLS; PIPERIDINES; PREFRONTAL CORTEX; PROTEIN SUBUNITS; PYRAMIDAL CELLS; QUINOXALINES; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, SMALL INTERFERING;

EID: 24644506107     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2005.08.014     Document Type: Article

References (67)

1. E. Arrigoni, and R.W. Greene Schaffer collateral and perforant path inputs activate different subtypes of NMDA receptors on the same CA1 pyramidal cell Br. J. Pharmacol. 142 2004 317 322
2. A. Artola, S. Brocher, and W. Singer Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex Nature 347 1990 69 72
3. Y.P. Auberson, H. Allgeier, S. Bischoff, K. Lingenhoehl, R. Moretti, and M. Schmutz 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition Bioorg. Med. Chem. Lett. 12 2002 1099 1102
4. T. Bast, W.N. Zhang, and J. Feldon Dorsal hippocampus and classical fear conditioning to tone and context in rats: effects of local NMDA-receptor blockade and stimulation Hippocampus 13 2003 657 675
5. M.F. Bear, and A. Kirkwood Neocortical long-term potentiation Curr. Opin. Neurobiol. 3 1993 197 202
6. G.Q. Bi, and M.M. Poo Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type J. Neurosci. 18 1998 10464 10472
7. T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39
8. M.D. Cassell, and D.J. Wright Topography of projections from the medial prefrontal cortex to the amygdala in the rat Brain Res. Bull. 17 1986 321 333
9. G.L. Collingridge, and W. Singer Excitatory amino acid receptors and synaptic plasticity Trends Pharmacol. Sci. 11 1990 290 296
10. Z. Cui, H. Wang, Y. Tan, K.A. Zaia, S. Zhang, and J.Z. Tsien Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain Neuron 41 2004 781 793
11. O. Devinsky, M.J. Morrell, and B.A. Vogt Contributions of anterior cingulate cortex to behaviour Brain 118 1995 279 306
12. A.W. Dunah, and D.G. Standaert Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane J. Neurosci. 21 2001 5546 5558
13. M.S. Fanselow Contextual fear, gestalt memories, and the hippocampus Behav. Brain Res. 110 2000 73 81
14. M.S. Fanselow, J.J. Kim, J. Yipp, and B. De Oca Differential effects of the N-methyl-D-aspartate antagonist DL-2-amino-5-phosphonovalerate on acquisition of fear of auditory and contextual cues Behav. Neurosci. 108 1994 235 240
15. G. Fischer, V. Mutel, G. Trube, P. Malherbe, J.N. Kew, E. Mohacsi, M.P. Heitz, and J.A. Kemp Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro J. Pharmacol. Exp. Ther. 283 1997 1285 1292
16. P.W. Frankland, C. O'Brien, M. Ohno, A. Kirkwood, and A.J. Silva Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory Nature 411 2001 309 313
17. P.W. Frankland, B. Bontempi, L.E. Talton, L. Kaczmarek, and A.J. Silva The involvement of the anterior cingulate cortex in remote contextual fear memory Science 304 2004 881 883
18. K.B.J. Franklin, and G. Paxinos The Mouse Brain in Stereotaxic Coordinates 1997 Academic Press New York
19. Y.J. Gao, W.H. Ren, Y.Q. Zhang, and Z.Q. Zhao Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats Pain 110 2004 343 353
20. J.C. Gewirtz, W.A. Falls, and M. Davis Normal conditioned inhibition and extinction of freezing and fear-potentiated startle following electrolytic lesions of medical prefrontal cortex in rats Behav. Neurosci. 111 1997 712 726
21. C.J. Han, C.M. O'Tuathaigh, L. van Trigt, J.J. Quinn, M.S. Fanselow, R. Mongeau, C. Koch, and D.J. Anderson Trace but not delay fear conditioning requires attention and the anterior cingulate cortex Proc. Natl. Acad. Sci. USA 100 2003 13087 13092
22. C.J. Hatton, and P. Paoletti Modulation of triheteromeric NMDA receptors by N-terminal domain ligands Neuron 46 2005 261 274
23. M.L. Hayashi, S.Y. Choi, B.S. Rao, H.Y. Jung, H.K. Lee, D. Zhang, S. Chattarji, A. Kirkwood, and S. Tonegawa Altered cortical synaptic morphology and impaired memory consolidation in forebrain-specific dominant-negative PAK transgenic mice Neuron 42 2004 773 787
24. J.P. Johansen, and H.L. Fields Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal Nat. Neurosci. 7 2004 398 403
25. L.V. Kalia, J.R. Gingrich, and M.W. Salter Src in synaptic transmission and plasticity Oncogene 23 2004 8007 8016
26. Y. Kiyama, T. Manabe, K. Sakimura, F. Kawakami, H. Mori, and M. Mishina Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunit J. Neurosci. 18 1998 6704 6712
27. D.C. Knight, D.T. Cheng, C.N. Smith, E.A. Stein, and F.J. Helmstetter Neural substrates mediating human delay and trace fear conditioning J. Neurosci. 24 2004 218 228
28. G. Kohr, V. Jensen, H.J. Koester, A.L. Mihaljevic, J.K. Utvik, A. Kvello, O.P. Ottersen, P.H. Seeburg, R. Sprengel, and O. Hvalby Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction J. Neurosci. 23 2003 10791 10799
29. J. Lisman Long-term potentiation: outstanding questions and attempted synthesis Philos. Trans. R. Soc. Lond. B Biol. Sci. 358 2003 829 842
30. L. Liu, T.P. Wong, M.F. Pozza, K. Lingenhoehl, Y. Wang, M. Sheng, Y.P. Auberson, and Y.T. Wang Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity Science 304 2004 1021 1024
31. J.M. Loftis, and A. Janowsky The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications Pharmacol. Ther. 97 2003 55 85
32. Y.M. Lu, J.C. Roder, J. Davidow, and M.W. Salter Src activation in the induction of long-term potentiation in CA1 hippocampal neurons Science 279 1998 1363 1367
33. R.C. Malenka, and R.A. Nicoll NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms Trends Neurosci. 16 1993 521 527
34. A.P. Mallon, Y.P. Auberson, and T.W. Stone Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-D: -aspartate receptors in hippocampal slices Exp. Brain Res. 162 2005 374 383
35. H. Markram, J. Lubke, M. Frotscher, and B. Sakmann Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs Science 275 1997 213 215
36. P.V. Massey, B.E. Johnson, P.R. Moult, Y.P. Auberson, M.W. Brown, E. Molnar, G.L. Collingridge, and Z.I. Bashir Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression J. Neurosci. 24 2004 7821 7828
37. T. Maviel, T.P. Durkin, F. Menzaghi, and B. Bontempi Sites of neocortical reorganization critical for remote spatial memory Science 305 2004 96 99
38. T.J. McHugh, K.I. Blum, J.Z. Tsien, S. Tonegawa, and M.A. Wilson Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice Cell 87 1996 1339 1349
39. M.R. Milad, and G.J. Quirk Neurons in medial prefrontal cortex signal memory for fear extinction Nature 420 2002 70 74
40. H. Monyer, N. Burnashev, D.J. Laurie, B. Sakmann, and P.H. Seeburg Developmental and regional expression in the rat brain and functional properties of four NMDA receptors Neuron 12 1994 529 540
41. M.A. Morgan, and J.E. LeDoux Contribution of ventrolateral prefrontal cortex to the acquisition and extinction of conditioned fear in rats Neurobiol. Learn. Mem. 72 1999 244 251
42. B.A. Morrow, J.D. Elsworth, F.M. Inglis, and R.H. Roth An antisense oligonucleotide reverses the footshock-induced expression of fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility J. Neurosci. 19 1999 5666 5673
43. A. Munoz, T.M. Woods, and E.G. Jones Laminar and cellular distribution of AMPA, kainate, and NMDA receptor subunits in monkey sensory-motor cortex J. Comp. Neurol. 407 1999 472 490
44. R.A. Nicoll, and R.C. Malenka Contrasting properties of two forms of long-term potentiation in the hippocampus Nature 377 1995 115 118
45. L.M. Ritter, D.M. Vazquez, and J.H. Meador-Woodruff Ontogeny of ionotropic glutamate receptor subunit expression in the rat hippocampus Brain Res. Dev. Brain Res. 139 2002 227 236
46. S.M. Rodrigues, G.E. Schafe, and J.E. LeDoux Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning J. Neurosci. 21 2001 6889 6896
47. S.M. Rodrigues, G.E. Schafe, and J.E. LeDoux Molecular mechanisms underlying emotional learning and memory in the lateral amygdala Neuron 44 2004 75 91
48. M.T. Rogan, U.V. Staubli, and J.E. LeDoux Fear conditioning induces associative long-term potentiation in the amygdala Nature 390 1997 604 607
49. P. Sah, and R.A. Nicoll Mechanisms underlying potentiation of synaptic transmission in rat anterior cingulate cortex in vitro J. Physiol. 433 1991 615 630
50. E. Santini, H. Ge, K. Ren, S. Pena de Ortiz, and G.J. Quirk Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex J. Neurosci. 24 2004 5704 5710
51. T. Shallice, P. Fletcher, C.D. Frith, P. Grasby, R.S. Frackowiak, and R.J. Dolan Brain regions associated with acquisition and retrieval of verbal episodic memory Nature 368 1994 633 635
52. M. Sheng, J. Cummings, L.A. Roldan, Y.N. Jan, and L.Y. Jan Changing subunit composition of heteromeric NMDA receptors during development of rat cortex Nature 368 1994 144 147
53. Y.P. Tang, E. Shimizu, G.R. Dube, C. Rampon, G.A. Kerchner, M. Zhuo, G. Liu, and J.Z. Tsien Genetic enhancement of learning and memory in mice Nature 401 1999 63 69
54. J. Tang, S. Ko, H.K. Ding, C.-S. Qiu, A.A. Calejesan, and M. Zhuo Pavlovian fear memory induced by activation in the anterior cingulate cortex Molecular Pain 1 2005 6
55. E. Tsvetkov, W.A. Carlezon, F.M. Benes, E.R. Kandel, and V.Y. Bolshakov Fear conditioning occludes LTP-induced presynaptic enhancement of synaptic transmission in the cortical pathway to the lateral amygdala Neuron 34 2002 289 300
56. E. Tsvetkov, R.M. Shin, and V.Y. Bolshakov Glutamate uptake determines pathway specificity of long-term potentiation in the neural circuitry of fear conditioning Neuron 41 2004 139 151
57. Y.T. Wang, and M.W. Salter Regulation of NMDA receptors by tyrosine kinases and phosphatases Nature 369 1994 233 235
58. F. Wei, P. Li, and M. Zhuo Loss of synaptic depression in mammalian anterior cingulate cortex after amputation J. Neurosci. 19 1999 9346 9354
59. F. Wei, G.D. Wang, G.A. Kerchner, S.J. Kim, H.M. Xu, Z.F. Chen, and M. Zhuo Genetic enhancement of inflammatory pain by forebrain NR2B overexpression Nat. Neurosci. 4 2001 164 169
60. F. Wei, C.S. Qiu, J. Liauw, D.A. Robinson, N. Ho, T. Chatila, and M. Zhuo Calcium calmodulin-dependent protein kinase IV is required for fear memory Nat. Neurosci. 5 2002 573 579
61. F. Wei, X.M. Xia, J. Tang, H. Ao, S. Ko, J. Liauw, C.S. Qiu, and M. Zhuo Calmodulin regulates synaptic plasticity in the anterior cingulate cortex and behavioral responses: a microelectroporation study in adult rodents J. Neurosci. 23 2003 8402 8409
62. K. Williams Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors Mol. Pharmacol. 44 1993 851 859
63. B.J. Wiltgen, R.A. Brown, L.E. Talton, and A.J. Silva New circuits for old memories: the role of the neocortex in consolidation Neuron 44 2004 101 108
64. R.W. Wong, M. Setou, J. Teng, Y. Takei, and N. Hirokawa Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice Proc. Natl. Acad. Sci. USA 99 2002 14500 14505
65. L.J. Wu, M.G. Zhao, H. Toyoda, S. Ko, and M. Zhuo Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex J. Neurophysiol. 94 2005 1805 1813
66. R.A. Zalutsky, and R.A. Nicoll Comparison of two forms of long-term potentiation in single hippocampal neurons Science 248 1990 1619 1624
67. M. Zhuo Glutamate receptors and persistent pain: targeting forebrain NR2B subunits Drug Discov. Today 7 2002 259 267