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Volumn 15, Issue 2, 2008, Pages 50-54

Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; RECEPTOR SUBUNIT; N METHYL D ASPARTATE RECEPTOR SUBTYPE 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N-METHYL D-ASPARTATE RECEPTOR SUBTYPE 2A; UNCLASSIFIED DRUG;

EID: 39349087613     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.777308     Document Type: Article
Times cited : (131)

References (43)
  • 1
    • 0036254386 scopus 로고    scopus 로고
    • Effects of stress and hippocampal NMDA receptor antagonism on recognition memory in rats
    • Baker, K.B. and Kim, J.J. 2002. Effects of stress and hippocampal NMDA receptor antagonism on recognition memory in rats. Learn. Mem. 9: 58-65.
    • (2002) Learn. Mem , vol.9 , pp. 58-65
    • Baker, K.B.1    Kim, J.J.2
  • 2
    • 33847047813 scopus 로고    scopus 로고
    • The drugs don't work - Or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-A-containing AMPA receptors to hippocampal-dependent memory
    • Bannerman, D.M., Rawlins, J.N., and Good, M.A. 2006. The drugs don't work - Or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-A-containing AMPA receptors to hippocampal-dependent memory. Psychopharmacology 188: 552-566.
    • (2006) Psychopharmacology , vol.188 , pp. 552-566
    • Bannerman, D.M.1    Rawlins, J.N.2    Good, M.A.3
  • 4
    • 33746902947 scopus 로고    scopus 로고
    • Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice
    • Boyce-Rustay, J.M. and Holmes, A. 2006a. Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice. Neuropsychopharmacology 31: 2405-2414.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2405-2414
    • Boyce-Rustay, J.M.1    Holmes, A.2
  • 5
    • 33746918785 scopus 로고    scopus 로고
    • Ethanol-related behaviors in mice lacking the NMDA receptor NR2A subunit
    • Boyce-Rustay, J.M. and Holmes, A. 2006b. Ethanol-related behaviors in mice lacking the NMDA receptor NR2A subunit. Psychopharmacology 187: 455-466.
    • (2006) Psychopharmacology , vol.187 , pp. 455-466
    • Boyce-Rustay, J.M.1    Holmes, A.2
  • 6
    • 33747365253 scopus 로고    scopus 로고
    • Executive functions in the heterozygous reeler mouse model of schizophrenia
    • Brigman, J.L., Padukiewicz, K.E., Sutherland, M.L., and Rothblat, L.A. 2006. Executive functions in the heterozygous reeler mouse model of schizophrenia. Behav. Neurosci. 120: 984-988.
    • (2006) Behav. Neurosci , vol.120 , pp. 984-988
    • Brigman, J.L.1    Padukiewicz, K.E.2    Sutherland, M.L.3    Rothblat, L.A.4
  • 7
    • 0030828693 scopus 로고    scopus 로고
    • Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat
    • Bussey, T.J., Muir, J.L., Everitt, B.J., and Robbins, T.W. 1997. Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat. Behav. Neurosci. 111: 920-936.
    • (1997) Behav. Neurosci , vol.111 , pp. 920-936
    • Bussey, T.J.1    Muir, J.L.2    Everitt, B.J.3    Robbins, T.W.4
  • 8
    • 0034898919 scopus 로고    scopus 로고
    • Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models
    • Bussey, T.J., Saksida, L.M., and Rothblat, L.A. 2001. Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models. Behav. Neurosci. 115: 957-960.
    • (2001) Behav. Neurosci , vol.115 , pp. 957-960
    • Bussey, T.J.1    Saksida, L.M.2    Rothblat, L.A.3
  • 9
    • 0026470993 scopus 로고
    • Activity-dependent decrease in NMDA receptor responses during development of the visual cortex
    • Carmignoto, G. and Vicini, S. 1992. Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258: 1007-1011.
    • (1992) Science , vol.258 , pp. 1007-1011
    • Carmignoto, G.1    Vicini, S.2
  • 10
    • 0141758246 scopus 로고    scopus 로고
    • Dissociable contributions of the orbitofrontal and infralimbic cortex to Pavlovian autoshaping and discrimination reversal learning: Further evidence for the functional heterogeneity of the rodent frontal cortex
    • Chudasama, Y. and Robbins, T.W. 2003. Dissociable contributions of the orbitofrontal and infralimbic cortex to Pavlovian autoshaping and discrimination reversal learning: Further evidence for the functional heterogeneity of the rodent frontal cortex. J. Neurosci. 23: 8771-8780.
    • (2003) J. Neurosci , vol.23 , pp. 8771-8780
    • Chudasama, Y.1    Robbins, T.W.2
  • 11
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy, S., Brickley, S., and Farrant, M. 2001. NMDA receptor subunits: Diversity, development and disease. Curr. Opin. Neurobiol. 11: 327-335.
    • (2001) Curr. Opin. Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 13
    • 0030053773 scopus 로고    scopus 로고
    • Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor ε1 subunit
    • Ito, I., Sakimura, K., Mishina, M., and Sugiyama, H. 1996. Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor ε1 subunit. Neurosci. Lett. 203: 69-71.
    • (1996) Neurosci. Lett , vol.203 , pp. 69-71
    • Ito, I.1    Sakimura, K.2    Mishina, M.3    Sugiyama, H.4
  • 15
    • 0015380517 scopus 로고
    • Limbic lesions and the problem of stimulus-reinforcement associations
    • Jones, B. and Mishkin, M. 1972. Limbic lesions and the problem of stimulus-reinforcement associations. Exp. Neurol. 36: 362-377.
    • (1972) Exp. Neurol , vol.36 , pp. 362-377
    • Jones, B.1    Mishkin, M.2
  • 17
    • 37249062748 scopus 로고    scopus 로고
    • NMDAR LTP and LTD induction: 2B or not 2B . . . Is that the question?
    • Kash, T. and Winder, D.G. 2007. NMDAR LTP and LTD induction: 2B or not 2B . . . Is that the question? Debates Neurosci. 1: 79-84.
    • (2007) Debates Neurosci , vol.1 , pp. 79-84
    • Kash, T.1    Winder, D.G.2
  • 18
    • 0029941251 scopus 로고    scopus 로고
    • Experience-dependent modification of synaptic plasticity in visual cortex
    • Kirkwood, A., Rioult, M.C., and Bear, M.F. 1996. Experience-dependent modification of synaptic plasticity in visual cortex. Nature 381: 526-528.
    • (1996) Nature , vol.381 , pp. 526-528
    • Kirkwood, A.1    Rioult, M.C.2    Bear, M.F.3
  • 19
  • 20
    • 0032171371 scopus 로고    scopus 로고
    • Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunit
    • Kiyama, Y., Manabe, T., Sakimura, K., Kawakami, F., Mori, H., and Mishina, M. 1998. Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunit. J. Neurosci. 18: 6704-6712.
    • (1998) J. Neurosci , vol.18 , pp. 6704-6712
    • Kiyama, Y.1    Manabe, T.2    Sakimura, K.3    Kawakami, F.4    Mori, H.5    Mishina, M.6
  • 21
    • 33748921093 scopus 로고    scopus 로고
    • NMDA receptor function: Subunit composition versus spatial distribution
    • Kohr, G. 2006. NMDA receptor function: Subunit composition versus spatial distribution. Cell Tissue Res. 326: 439-446.
    • (2006) Cell Tissue Res , vol.326 , pp. 439-446
    • Kohr, G.1
  • 22
    • 39549084340 scopus 로고    scopus 로고
    • Experience-dependent changes in NMDA receptor composition at mature central synapses
    • Kopp, C., Longordo, F., and Luthi, A. 2007. Experience-dependent changes in NMDA receptor composition at mature central synapses. Neuropharmacology 326: 439-446.
    • (2007) Neuropharmacology , vol.326 , pp. 439-446
    • Kopp, C.1    Longordo, F.2    Luthi, A.3
  • 23
    • 0032523002 scopus 로고    scopus 로고
    • Evidence for a tetrameric structure of recombinant NMDA receptors
    • Laube, B., Kuhse, J., and Betz, H. 1998. Evidence for a tetrameric structure of recombinant NMDA receptors. J. Neurosci. 18: 2954-2961.
    • (1998) J. Neurosci , vol.18 , pp. 2954-2961
    • Laube, B.1    Kuhse, J.2    Betz, H.3
  • 24
    • 0035013259 scopus 로고    scopus 로고
    • Olfactory learning modifies predisposition for long-term potentiation and long-term depression induction in the rat piriform (olfactory) cortex
    • Lebel, D., Grossman, Y., and Barkai, E. 2001. Olfactory learning modifies predisposition for long-term potentiation and long-term depression induction in the rat piriform (olfactory) cortex. Cereb. Cortex 11: 485-489.
    • (2001) Cereb. Cortex , vol.11 , pp. 485-489
    • Lebel, D.1    Grossman, Y.2    Barkai, E.3
  • 25
    • 33749366150 scopus 로고    scopus 로고
    • Learning in the absence of experience-dependent regulation of NMDAR composition
    • Lebel, D., Sidhu, N., Barkai, E., and Quinlan, E.M. 2006. Learning in the absence of experience-dependent regulation of NMDAR composition. Learn. Mem. 13: 566-570.
    • (2006) Learn. Mem , vol.13 , pp. 566-570
    • Lebel, D.1    Sidhu, N.2    Barkai, E.3    Quinlan, E.M.4
  • 26
    • 5444222139 scopus 로고    scopus 로고
    • Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development
    • Liu, X.B., Murray, K.D., and Jones, E.G. 2004. Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. J. Neurosci. 24: 8885-8895.
    • (2004) J. Neurosci , vol.24 , pp. 8885-8895
    • Liu, X.B.1    Murray, K.D.2    Jones, E.G.3
  • 27
    • 0034969860 scopus 로고    scopus 로고
    • Influence of diet restriction on NMDA receptor subunits and learning during aging
    • Magnusson, K.R. 2001. Influence of diet restriction on NMDA receptor subunits and learning during aging. Neurobiol. Aging 22: 613-627.
    • (2001) Neurobiol. Aging , vol.22 , pp. 613-627
    • Magnusson, K.R.1
  • 28
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • Malenka, R.C. and Bear, M.F. 2004. LTP and LTD: An embarrassment of riches. Neuron 44: 5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 30
    • 0035862965 scopus 로고    scopus 로고
    • Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor ε1 subunit
    • Miyamoto, Y., Yamada, K., Noda, Y., Mori, H., Mishina, M., and Nabeshima, T. 2001. Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor ε1 subunit. J. Neurosci. 21: 750-757.
    • (2001) J. Neurosci , vol.21 , pp. 750-757
    • Miyamoto, Y.1    Yamada, K.2    Noda, Y.3    Mori, H.4    Mishina, M.5    Nabeshima, T.6
  • 32
    • 32544450453 scopus 로고    scopus 로고
    • Relating NMDA receptor function to receptor subunit composition: Limitations of the pharmacological approach
    • Neyton, J. and Paoletti, P. 2006. Relating NMDA receptor function to receptor subunit composition: Limitations of the pharmacological approach. J. Neurosci. 26: 1331-1333.
    • (2006) J. Neurosci , vol.26 , pp. 1331-1333
    • Neyton, J.1    Paoletti, P.2
  • 33
    • 0028900455 scopus 로고
    • Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims
    • Nowak, G., Ordway, G.A., and Paul, I.A. 1995. Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res. 675: 157-164.
    • (1995) Brain Res , vol.675 , pp. 157-164
    • Nowak, G.1    Ordway, G.A.2    Paul, I.A.3
  • 34
    • 0347418175 scopus 로고    scopus 로고
    • Development and aging of N-methyl-D-aspartate receptor expression in the prefrontal/frontal cortex of mice
    • Ontl, T., Xing, Y., Bai, L., Kennedy, E., Nelson, S., Wakeman, M., and Magnusson, K. 2004. Development and aging of N-methyl-D-aspartate receptor expression in the prefrontal/frontal cortex of mice. Neuroscience 123: 467-479.
    • (2004) Neuroscience , vol.123 , pp. 467-479
    • Ontl, T.1    Xing, Y.2    Bai, L.3    Kennedy, E.4    Nelson, S.5    Wakeman, M.6    Magnusson, K.7
  • 35
    • 0038045581 scopus 로고    scopus 로고
    • Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex
    • Philpot, B.D., Espinosa, J.S., and Bear, M.F. 2003. Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex. J. Neurosci. 23: 5583-5588.
    • (2003) J. Neurosci , vol.23 , pp. 5583-5588
    • Philpot, B.D.1    Espinosa, J.S.2    Bear, M.F.3
  • 36
    • 0033359937 scopus 로고    scopus 로고
    • Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo
    • Quinlan, E.M., Philpot, B.D., Huganir, R.L., and Bear, M.F. 1999. Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat. Neurosci. 2: 352-357.
    • (1999) Nat. Neurosci , vol.2 , pp. 352-357
    • Quinlan, E.M.1    Philpot, B.D.2    Huganir, R.L.3    Bear, M.F.4
  • 37
    • 1642452716 scopus 로고    scopus 로고
    • A molecular mechanism for stabilization of learning-induced synaptic modifications
    • Quinlan, E.M., Lebel, D., Brosh, I., and Barkai, E. 2004. A molecular mechanism for stabilization of learning-induced synaptic modifications. Neuron 41: 185-192.
    • (2004) Neuron , vol.41 , pp. 185-192
    • Quinlan, E.M.1    Lebel, D.2    Brosh, I.3    Barkai, E.4
  • 38
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund, C., Stern-Bach, Y., and Stevens, C.F. 1998. The tetrameric structure of a glutamate receptor channel. Science 280: 1596-1599.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 41
    • 0035188745 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease
    • Sze, C., Bi, H., Kleinschmidt-DeMasters, B.K., Filley, C.M., and Martin, L.J. 2001. N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease. J. Neurol. Sci. 182: 151-159.
    • (2001) J. Neurol. Sci , vol.182 , pp. 151-159
    • Sze, C.1    Bi, H.2    Kleinschmidt-DeMasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 43
    • 24944557047 scopus 로고    scopus 로고
    • Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation
    • Weitlauf, C., Honse, Y., Auberson, Y.P., Mishina, M., Lovinger, D.M., and Winder, D.G. 2005. Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation. J. Neurosci. 25: 8386-8390.
    • (2005) J. Neurosci , vol.25 , pp. 8386-8390
    • Weitlauf, C.1    Honse, Y.2    Auberson, Y.P.3    Mishina, M.4    Lovinger, D.M.5    Winder, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.