1H-[ 13C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism

Biological Psychiatry

Volumn 71, Issue 11, 2012, Pages 1022-1025

  Chowdhury, Golam M I ^a   Behar, Kevin L ^a   Cho, William ^b   Thomas, Monique A ^a   Rothman, Douglas L ^a   Sanacora, Gerard ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

GABA; glutamate glutamine cycle; ketamine; magnetic resonance spectroscopy; medial prefrontal cortex; NMDA

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; KETAMINE; SODIUM CHLORIDE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AMINO ACID RECEPTOR BLOCKING AGENT; CARBON; DIAGNOSTIC AGENT; HYDROGEN;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN NERVE CELL; CARBON NUCLEAR MAGNETIC RESONANCE; COGNITION; CONTROLLED STUDY; DRUG EFFECT; ENERGY METABOLISM; EX VIVO STUDY; GLIA CELL; HEAD MOVEMENT; HIPPOCAMPUS; HYPERACTIVITY; IMMOBILIZATION; MALE; MOOD; NONHUMAN; PERCEPTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STEREOTYPY; AFFECT; ANIMAL; GLIA; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SCINTISCANNING; SPRAGUE DAWLEY RAT;

AFFECT; ANIMALS; CARBON ISOTOPES; COGNITION; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; HIPPOCAMPUS; HYDROGEN; KETAMINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEUROGLIA; NEUROTRANSMITTER AGENTS; PERCEPTION; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84861093240     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.11.006     Document Type: Article

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