A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference

Addiction Biology

Volumn 16, Issue 3, 2011, Pages 428-439

  Camp, Marguerite C ^a   Feyder, Michael ^a   Ihne, Jessica ^a   Palachick, Benjamin ^a   Hurd, Benita ^a   Karlsson, Rose Marie ^a   Noronha, Bianca ^a   Chen, Yi Chyan ^b   Coba, Marcelo P ^c   Grant, Seth G N ^c   Holmes, Andrew ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Alcohol; Alcoholism; Glutamate; MAGUK; Mouse; Synapse

Indexed keywords

DIZOCILPINE; LITHIUM CHLORIDE; POSTSYNAPTIC DENSITY PROTEIN 95;

ALCOHOL INTOXICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; CONTROLLED STUDY; DRINKING BEHAVIOR; FEMALE; HYPERSENSITIVITY; HYPNOSIS; HYPOTHERMIA; MALE; MOUSE; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SEDATION; TASTE AVERSION;

ALCOHOL DRINKING; ALCOHOLIC INTOXICATION; ANIMALS; ANTIMANIC AGENTS; ASSOCIATION LEARNING; CHOICE BEHAVIOR; CONDITIONING, CLASSICAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GUANYLATE KINASE; INJECTIONS, INTRAPERITONEAL; LITHIUM CHLORIDE; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SOCIAL ENVIRONMENT; TASTE;

EID: 79959825736     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2010.00282.x     Document Type: Article

References (41)

1. Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL (2009) PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. J Neurosci 29:7124-7136.
2. Boyce-Rustay JM, Cameron HA, Holmes A (2007) Chronic swim stress alters sensitivity to acute behavioral effects of ethanol in mice. Physiol Behav 91:77-86. (Pubitemid 46616879)
3. Boyce-Rustay JM, Holmes A (2005) Functional roles of NMDA receptor NR2A and NR2B subunits in the acute intoxicating effects of ethanol in mice. Synapse 56:222-225. (Pubitemid 40656645)
4. Boyce-Rustay JM, Holmes A (2006) Ethanol-related behaviors in mice lacking the NMDA receptor NR2A subunit. Psychopharmacology (Berl) 187:455-466. (Pubitemid 44200517)
5. Boyce-Rustay JM, Wiedholz LM, Millstein RA, Carroll J, Murphy DL, Daws LC, Holmes A (2006) Ethanol-related behaviors in serotonin transporter knockout mice. Alcohol Clin Exp Res 30:1957-1965. (Pubitemid 44749521)
6. Carpenter-Hyland EP, Chandler LJ (2006) Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines. Eur J Neurosci 24:3496-3506.
7. Chandler LJ (2003) Ethanol and brain plasticity: receptors and molecular networks of the postsynaptic density as targets of ethanol. Pharmacol Ther 99:311-326.
8. Chen YC, Holmes A (2009) Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: modulation by genetic strain and stress. Neuropsychopharmacology 34:1454-1466.
9. Coba MP, Pocklington AJ, Collins MO, Kopanitsa MV, Uren RT, Swamy S, Croning MD, Choudhary JS, Grant SG (2009) Neurotransmitters drive combinatorial multistate postsynaptic density networks. Sci Signal 2:ra19.
10. Crabbe J, Cameron A, Munn E, Bunning M, Wahlsten D (2008) Overview of mouse assays of ethanol intoxication. Curr Protoc Neurosci; suppl 42: 9.26.1-9.26.19.
11. Crabbe JC, Phillips TJ, Harris RA, Arends MA, Koob GF (2006) Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol 11:195-269. (Pubitemid 46696913)
12. Cunningham CL, Henderson CM, Bormann NM (1998) Extinction of ethanol-induced conditioned place preference and conditioned place aversion: effects of naloxone. Psychopharmacology (Berl) 139:62-70. (Pubitemid 28416883)
13. Cunningham CL, Niehus DR, Malott DH, Prather LK (1992) Genetic differences in the rewarding and activating effects of morphine and ethanol. Psychopharmacology (Berl) 107:385-393.
14. Daws LC, Montanez S, Munn JL, Owens WA, Baganz NL, Boyce-Rustay JM, Millstein RA, Wiedholz LM, Murphy DL, Holmes A (2006) Ethanol inhibits clearance of brain serotonin by a serotonin transporter-independent mechanism. J Neurosci 26:6431-6438. (Pubitemid 44318324)
15. Elias GM, Nicoll RA (2007) Synaptic trafficking of glutamate receptors by MAGUK scaffolding proteins. Trends Cell Biol 17:343-352. (Pubitemid 47102201)
16. Elkobi A, Ehrlich I, Belelovsky K, Barki-Harrington L, Rosenblum K (2008) ERK-dependent PSD-95 induction in the gustatory cortex is necessary for taste learning, but not retrieval. Nat Neurosci 11:1149-1151.
17. Everitt BJ, Robbins TW (2005) Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 8:1481-1489. (Pubitemid 41573659)
18. Fernandez E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, Croning MD, Zografos L, Armstrong JD, Choudhary JS, Grant SG (2009) Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol 5:269.
19. Feyder M, Karlsson RM, Mathur P, Lyman M, Bock R, Momezan R, Munasinghe J, Scattoni ML, Ihne J, Camp M, Graybeal C, Strathdee DJ, Begg A, Alvarez VA, Kirsch P, Rietschel M, Cichon S, Walter H, Meyer-Lindenberg A, Grant SGN, Holmes A (2010) Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism-spectrum disorders and Williams' (e.g. Williams') syndrome. Am J Psychiatry 2010; 167:1508-1517.
20. Gass JT, Olive MF (2008) Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol 75:218-265. (Pubitemid 350235390)
21. George DT, Gilman J, Hersh J, Thorsell A, Herion D, Geyer C, Peng X, Kielbasa W, Rawlings R, Brandt JE, Gehlert DR, Tauscher JT, Hunt SP, Hommer D, Heilig M (2008) Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science 319:1536-1539. (Pubitemid 351398184)
22. Grant SG, Marshall MC, Page KL, Cumiskey MA, Armstrong JD (2005) Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases. Hum Mol Genet 14 Spec No 2:R225-R234. (Pubitemid 41631891)
23. Hefner K, Holmes A (2007) An investigation of the behavioral actions of ethanol across adolescence in mice. Psychopharmacology (Berl) 191:311-322. (Pubitemid 46354607)
24. Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson RM, Saksida LM, Bussey TJ, Singewald N, Holmes A (2008) Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain. J Neurosci 28:8074-8085.
25. Kalivas PW, O'Brien C (2008) Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacology 33:166-180. (Pubitemid 350191316)
26. Karlsson RM, Hefner KR, Sibley DR, Holmes A (2008) Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization. Psychopharmacology (Berl) 200:117-127.
27. Khisti RT, Wolstenholme J, Shelton KL, Miles MF (2006) Characterization of the ethanol-deprivation effect in substrains of C57BL/6 mice. Alcohol 40:119-126. (Pubitemid 46329323)
28. Kim E, Sheng M (2004) PDZ domain proteins of synapses. Nat Rev Neurosci 5:771-781. (Pubitemid 39336214)
29. Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Souza DC (2003) N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Ther 99:79-94. (Pubitemid 36694751)
30. Lovinger DM, White G, Weight FF (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243:1721-1724. (Pubitemid 19106970)
31. Malenka RC, Bear MF (2004) LTP and LTD: an embarrassment of riches. Neuron 44:5-21. (Pubitemid 39348827)
32. Millstein RA, Ralph RJ, Yang RJ, Holmes A (2006) Effects of repeated maternal separation on prepulse inhibition of startle across inbred mouse strains. Genes Brain Behav 5:346-354. (Pubitemid 43794817)
33. Newlin DB, Thomson JB (1990) Alcohol challenge with sons of alcoholics: a critical review and analysis. Psychol Bull 108:383-402.
34. Newton PM, Messing RO (2006) Intracellular signaling pathways that regulate behavioral responses to ethanol. Pharmacol Ther 109:227-237. (Pubitemid 41740823)
35. Palachick B, Chen YC, Enoch AJ, Karlsson RM, Mishina M, Holmes A (2008) Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication. Alcohol Clin Exp Res 32:1479-1492.
36. Ron D (2004) Signaling cascades regulating NMDA receptor sensitivity to ethanol. Neuroscientist 10:325-336.
37. Rustay NR, Wahlsten D, Crabbe JC (2003) Influence of task parameters on rotarod performance and sensitivity to ethanol in mice. Behav Brain Res 141:237-249. (Pubitemid 36542972)
38. Schuckit MA (1994) Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151:184-189.
39. Shen EH, Phillips TJ (1998) MK-801 potentiates ethanol's effects on locomotor activity in mice. Pharmacol Biochem Behav 59:135-143. (Pubitemid 28053691)
40. Woodward JJ (2000) Ethanol and NMDA receptor signaling. Crit Rev Neurobiol 14:69-89.
41. Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG (2004) Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron 41:625-638. (Pubitemid 38253073)