BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-strand breaks during DNA replication

DNA Repair

Volumn 30, Issue , 2015, Pages 11-20

  Fridlich, Ram ^a   Annamalai, Devi ^a   Roy, Rohini ^a   Bernheim, Giana ^a   Powell, Simon N ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

BRCA; Cancer; Chromosome aberrations; Homologous recombination; Oxidative stress

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; HYDROGEN PEROXIDE; RAD51 PROTEIN; 8-HYDROXYGUANINE; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN, HUMAN; DNA; GUANINE; RAD51 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CELL CYCLE S PHASE; CELL GROWTH; CELL METABOLISM; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; FEMALE; HUMAN; HUMAN CELL; INTERSTITIAL CHROMOSOME DELETION; OXIDATIVE STRESS; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CHROMOSOME ABERRATION; DNA REPAIR; DRUG EFFECTS; GENETICS; MCF 7 CELL LINE; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; BRCA1 PROTEIN; BRCA2 PROTEIN; CHROMOSOME ABERRATIONS; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPLICATION; FEMALE; GUANINE; HUMANS; HYDROGEN PEROXIDE; MCF-7 CELLS; MUTATION; OXIDATIVE STRESS; RAD51 RECOMBINASE; S PHASE;

EID: 84925950305     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2015.03.002     Document Type: Article

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