Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae

Molecular and Cellular Biology

Volumn 19, Issue 4, 1999, Pages 2929-2935

  Swanson, Rebecca L ^a   Morey, Natalie J ^a   Doetsch, Paul W ^a   Jinks Robertson, Sue ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA BASE; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; HYDROGEN PEROXIDE; LYASE; MENADIONE; NUCLEOTIDE; OXIDIZING AGENT;

APURINIC SITE; APYRIMIDINIC SITE; ARTICLE; DNA BASE COMPOSITION; DNA DAMAGE; DNA RECOMBINATION; DNA SYNTHESIS; EXCISION REPAIR; FUNGUS MUTANT; GENE DISRUPTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0032913570     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.4.2929     Document Type: Article

References (40)

1. Augeri, L., Y. M. Lee, A. B. Barton, and P. W. Doetsch. 1997. Purification, characterization, gene cloning and expression of Saccharomyces cerevisiae redoxyendonuclease, a homolog of Escherichia coli endonuclease III. Biochemistry 36:721-729.
2. Barton, A. B., and D. B. Kaback. 1994. Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUN38-MAK16-SPO7 region. J. Bacteriol. 176:1872-1880.
3. Bierne, H., and B. Michel. 1994. When replication forks stop. Mol. Microbiol. 13:17-23.
4. Boeke, J. D., J. Trueheart, G. Natsoulis, and G. R. Fink. 1987 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154: 164-175.
5. Brennan, R. J., B. E. Swoboda, and R. H. Schiestl. 1994. Oxidative mutagens induce intrachromosomal recombination in yeast. Mutat. Res. 308:159-167.
6. Cooper, P. K., T. Nouspikel, S. G. Clarkson, and S. A. Leadon. 1997. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 275:990-993.
7. Cunningham, R. P., S. M. Saporito, S. G. Spitzer, and B. Weiss. 1986. Endonuclease IV (nfo) mutants of Escherichia coli. J. Bacteriol. 168:1120-1127.
8. Cunningham, R. P., and B. Weiss. 1985. Endonuclease III (nth) mutants of Escherichia coli. Proc. Natl. Acad. Sci. USA 82:474-478.
9. Datta, A., and S. Jinks-Robertson. 1995. Association of increased spontaneous mutation rates with high levels of transcription in yeast. Science 268: 1615-1619.
10. Davies, A. A., E. C. Friedberg, A. E. Tomkinson, R. D. Wood, and S. C. West. 1995. Role of Rad1 and Rad10 proteins in nucleotide excision repair and recombination. J. Biol. Chem. 270:24638-24641.
11. Eide, L., M. Bjoras, M. Pirovano, I. Alseth, K. G. Berdal, and E. Seeberg. 1996. Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli. Proc. Natl. Acad. Sci. USA 93:10735-10740.
12. Fishman-Lobell, J., and J. E. Haber. 1992. Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science 258:480-484.
13. Friedberg, E. C., G. C. Walker, and W. Siede. 1995. DNA repair and mutagenesis. ASM Press, Washington, D.C.
14. Gietz, D., A. S. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
15. Glassner, B. J., L. J. Rasmussen, M. T. Najarian, L. M. Posnick, and L. D. Samson. 1998. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proc. Natl. Acad. Sci. USA 95:9997-10002.
16. Greene, C. N., and S. Jinks-Robertson. 1997. Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. Mol. Cell. Biol. 17:2844-2850.
17. Habraken, Y., P. Sung, L. Prakash, and S. Prakash. 1993. Yeast excision repair gene RAD2 encodes a single strand endonuclease. Nature 366:365-368.
18. Hatahet, Z., Y. W. Kow, A. A. Purmal, R. P. Cunningham, and S. S. Wallace. 1994. New substrates for old enzymes: 5-hydroxy-2′-deoxycytidine and 5-hydroxy-2′-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2′-deoxyuridine is a substrate for uracil DNA N-glycosylase. J. Biol. Chem. 269:18814-18820.
19. Huang, J. C., D. S. Hsu, A. Kazantsev, and A. Sancar. 1994. Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc. Natl. Acad. Sci. USA 91:12213-12217.
20. Jinks-Robertson, S., and T. D. Petes. 1993. Experimental determination of rates of concerted evolution. Methods Enzymol. 224:631-646.
21. Johnson, R. E., C. A. Torres-Ramos, T. Izumi, S. Mitra, S. Prakash, and L. Prakash. 1998. Identification of APN2, the Saccharomyces cerevisiae homolog of the major AP endonuclease HAP1, and its role in the repair of abasic sites. Genes Dev. 12:3137-3143.
22. Kaytor, M. D., and D. M. Livingston. 1994. Saccharomyces cerevisiae RAD52 alleles temperature-sensitive for the repair of DNA double-strand breaks. Genetics 137:933-944.
23. Lea, D. E., and C. A. Coulson. 1949. The distribution of the numbers of mutants in bacterial populations. J. Genet. 49:264-285.
24. Moller, P., and H. Wallin. 1998. Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation. Mutat. Res. 410:271-290.
25. Nelson, J. R., C. W. Lawrence, and D. C. Hinkle. 1996. Thymine-thymine dimer bypass by yeast DNA polymerase ζ. Science 272:1646-1649.
26. Nutter, L. M., E. O. Ngo, G. R. Fisher, and P. L. Gutierrez. 1992. DNA strand scission and free radical production in menadione-treated cells. J. Biol. Chem. 267:2474-2479.
27. Petes, T. D., R. E. Malone, and L. S. Symington. 1991. Recombination in yeast, p. 407-521. In J. R. Broach, J. R. Pringle, and E. W. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. I. Genome dynamics, protein synthesis, and energetics. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
28. Ramotar, D., S. C. Popoff, E. B. Gralla, and B. Demple. 1991. Cellular role of yeast Apn1 apurinic endonuclease/3′-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol. Cell. Biol. 11:4537-4544.
29. Reardon, J. T., T. Bessho, H. C. Kung, P. H. Bolton, and A. Sancar. 1997. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. USA 94:9463-9468.
30. Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281-301.
31. Saparbaev, M., L. Prakash, and S. Prakash. 1996. Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae. Genetics 142:727-736.
32. Senturker, S., P. A. van der Kemp, H. J. You, P. W. Doetsch, M. Dizdaroglu, and S. Boiteux. 1998. Substrate specificity of the Ntg1 and Ntg2 proteins of Saccharomyces cerevisiae for modified bases in oxidatively damaged DNA. Nucleic Acids Res. 26:5270-5276.
33. Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3-20.
34. Snowden, A., Y. W. Kow, and B. V. Houten. 1990. Damage repertoire of Escherichia coli UvrABC nuclease complex includes abasic sites, base-damage analogues, and lesions containing adjacent 5′ or 3′ nicks. Biochemistry 29:7254-7259.
35. Sweder, K. S., and P. C. Hanawalt. 1992. Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription. Proc. Natl. Acad. Sci. USA 89: 10696-106700.
36. Tishkoff, D. X., N. Filosi, G. M. Gaida, and R. D. Kolodner. 1997. A novel mutation avoidance mechanism dependent on Saccharomyces cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 88:253-263.
37. Wach, A., A. Brachat, R. Pohlmann, and P. Philippsen. 1994. New heterologous modules for classical PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10:1793-1808.
38. Xiao, W., and B. L. Chow. 1998. Synergism between yeast nucleotide and base excision repair pathways in the protection against DNA methylation damage. Curr. Genet. 33:92-99.
39. Yap, W. Y., and K. N. Kreuzer. 1991. Recombination hotspots in bacteriophage T4 are dependent on replication origins. Proc. Natl. Acad. Sci. USA 88:6043-6047.
40. You, H. J., R. L. Swanson, and P. W. Doetsch. 1998. Saccharomyces cerevisiae possesses two functional homologs of Escherichia coli endonuclease III. Biochemistry 37:6033-6040.