Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of 8,5′-cyclopurine-2′-deoxynucleosides and 8-hydroxy-2′- deoxyguanosine

Biochemistry

Volumn 46, Issue 9, 2007, Pages 2488-2496

  Rodriguez, Henry ^a,e   Jaruga, Pawel ^b,c   Leber, Dennis ^a   Nyaga, Simon G ^d   Evans, Michele K ^d   Dizdaroglu, Miral ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b University of Marylandw Baltimore County   (United States)

^c NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CARCINOGENESIS; LYMPHOBLASTS; OVARIAN CANCER;

CELLS; DNA; GENES; IONIZING RADIATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENESIS;

TUMORS;

5',8 CYCLODEOXYGUANOSINE; 8 HYDROXYDEOXYGUANOSINE; 8,5' CYCLO 2' DEOXYADENOSINE; 8,5' CYCLOPURINE 2' DEOXYNUCLEOSIDE; BRCA1 PROTEIN; DEOXYADENOSINE DERIVATIVE; DEOXYGUANOSINE DERIVATIVE; DNA; NITROGEN 15; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; FEMALE; GAMMA IRRADIATION; GAS CHROMATOGRAPHY; GENE MUTATION; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; LYMPHOBLAST; MASS SPECTROMETRY; ONCOGENE; PRIORITY JOURNAL;

CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DEOXYGUANOSINE; DNA DAMAGE; DNA REPAIR; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENES, BRCA1; HUMANS; MALE; MASS SPECTROMETRY; MUTATION; OXIDATION-REDUCTION; PURINE NUCLEOSIDES;

EID: 33847665533     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi062022p     Document Type: Article

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