9 H -purine scaffold reveals induced-fit pocket plasticity of the brd9 bromodomain

Journal of Medicinal Chemistry

Volumn 58, Issue 6, 2015, Pages 2718-2736

  Picaud, Sarah ^a   Strocchia, Maria ^b   Terracciano, Stefania ^b   Lauro, Gianluigi ^b   Mendez, Jacqui ^c   Daniels, Danette L ^c   Riccio, Raffaele ^b   Bifulco, Giuseppe ^b   Bruno, Ines ^b   Filippakopoulos, Panagis ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SALERNO   (Italy)

^c PROMEGA CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINE 9H PURINE; PROTEOME; PURINE DERIVATIVE; UNCLASSIFIED DRUG; BRD9 PROTEIN, HUMAN; CHROMATIN; HISTONE; PURINE; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; BIOLUMINESCENCE; CHROMATIN; CYTOTOXICITY; ISOTHERMAL TITRATION CALORIMETRY; PLASTICITY; PROTEIN DOMAIN; PROTEIN STRUCTURE; SUZUKI REACTION; AMINATION; BINDING SITE; CHEMISTRY; HEK293 CELL LINE; HUMAN; METABOLISM; X RAY CRYSTALLOGRAPHY;

AMINATION; BINDING SITES; CHROMATIN; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HISTONES; HUMANS; PURINES; TRANSCRIPTION FACTORS;

EID: 84925938831     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm501893k     Document Type: Article

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