메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages 1-6

IL-35: A potential therapeutic target for controlling hepatitis B virus infection

Author keywords

Hepatitis B virus; Human interleukin 35; Immunotherapy; ITr35; Regulatory T lymphocytes

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 35; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, HUMAN;

EID: 84925875466     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/1751-2980.12218     Document Type: Article
Times cited : (39)

References (84)
  • 1
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison LW, Workman CJ, Kuo TT etal. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007; 450: 566-569.
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3
  • 2
    • 36248970671 scopus 로고    scopus 로고
    • IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells
    • Niedbala W, Wei XQ, Cai B etal. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. Eur J Immunol 2007; 37: 3021-3029.
    • (2007) Eur J Immunol , vol.37 , pp. 3021-3029
    • Niedbala, W.1    Wei, X.Q.2    Cai, B.3
  • 3
    • 84864124859 scopus 로고    scopus 로고
    • IL-12 family cytokines: immunological playmakers
    • Vignali DA, Kuchroo VK. IL-12 family cytokines: immunological playmakers. Nat Immunol 2012; 13: 722-728.
    • (2012) Nat Immunol , vol.13 , pp. 722-728
    • Vignali, D.A.1    Kuchroo, V.K.2
  • 4
    • 55149104594 scopus 로고    scopus 로고
    • Interleukin-35: odd one out or part of the family?
    • Collison LW, Vignali DA. Interleukin-35: odd one out or part of the family? Immunol Rev 2008; 226: 248-262.
    • (2008) Immunol Rev , vol.226 , pp. 248-262
    • Collison, L.W.1    Vignali, D.A.2
  • 5
    • 80053573336 scopus 로고    scopus 로고
    • Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily
    • Jones LL, Vignali DA. Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily. Immunol Res 2011; 51: 5-14.
    • (2011) Immunol Res , vol.51 , pp. 5-14
    • Jones, L.L.1    Vignali, D.A.2
  • 6
    • 69749101475 scopus 로고    scopus 로고
    • The IL-12 family of cytokines in infection, inflammation and autoimmune disorders
    • Gee K, Guzzo C, Che Mat NF, Ma W, Kumar A. The IL-12 family of cytokines in infection, inflammation and autoimmune disorders. Inflamm Allergy Drug Targets 2009; 8: 40-52.
    • (2009) Inflamm Allergy Drug Targets , vol.8 , pp. 40-52
    • Gee, K.1    Guzzo, C.2    Che Mat, N.F.3    Ma, W.4    Kumar, A.5
  • 7
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B etal. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 8
    • 18444385868 scopus 로고    scopus 로고
    • IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells
    • Pflanz S, Timans JC, Cheung J etal. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity 2002; 16: 779-790.
    • (2002) Immunity , vol.16 , pp. 779-790
    • Pflanz, S.1    Timans, J.C.2    Cheung, J.3
  • 9
    • 84857193362 scopus 로고    scopus 로고
    • The composition and signaling of the IL-35 receptor are unconventional
    • Collison LW, Delgoffe GM, Guy CS etal. The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol 2012; 13: 290-299.
    • (2012) Nat Immunol , vol.13 , pp. 290-299
    • Collison, L.W.1    Delgoffe, G.M.2    Guy, C.S.3
  • 10
    • 84895534422 scopus 로고    scopus 로고
    • Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance
    • Olson BM, Sullivan JA, Burlingham WJ. Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance. Front Immunol 2013; 4: 315.
    • (2013) Front Immunol , vol.4 , pp. 315
    • Olson, B.M.1    Sullivan, J.A.2    Burlingham, W.J.3
  • 11
    • 80053602996 scopus 로고    scopus 로고
    • Interpreting mixed signals: the cell's cytokine conundrum
    • Delgoffe GM, Murray PJ, Vignali DA. Interpreting mixed signals: the cell's cytokine conundrum. Curr Opin Immunol 2011; 23: 632-638.
    • (2011) Curr Opin Immunol , vol.23 , pp. 632-638
    • Delgoffe, G.M.1    Murray, P.J.2    Vignali, D.A.3
  • 12
    • 0030067819 scopus 로고    scopus 로고
    • A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
    • Devergne O, Hummel M, Koeppen H etal. A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J Virol 1996; 70: 1143-1153.
    • (1996) J Virol , vol.70 , pp. 1143-1153
    • Devergne, O.1    Hummel, M.2    Koeppen, H.3
  • 13
    • 0030700003 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
    • Devergne O, Birkenbach M, Kieff E. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proc Natl Acad Sci U S A 1997; 94: 12041-12046.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12041-12046
    • Devergne, O.1    Birkenbach, M.2    Kieff, E.3
  • 14
    • 0036898888 scopus 로고    scopus 로고
    • Interleukin is as interleukin does
    • Schrader JW. Interleukin is as interleukin does. Trends Immunol 2002; 23: 573-574.
    • (2002) Trends Immunol , vol.23 , pp. 573-574
    • Schrader, J.W.1
  • 15
    • 59749103715 scopus 로고    scopus 로고
    • Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3
    • Allan SE, Zhao XS, Abraham T, McMurchy AN, Levings MK. Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3. Eur J Immunol 2008; 38: 3282-3289.
    • (2008) Eur J Immunol , vol.38 , pp. 3282-3289
    • Allan, S.E.1    Zhao, X.S.2    Abraham, T.3    McMurchy, A.N.4    Levings, M.K.5
  • 17
    • 79959572627 scopus 로고    scopus 로고
    • Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance
    • Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA. Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. J Immunol 2011; 186: 6661-6666.
    • (2011) J Immunol , vol.186 , pp. 6661-6666
    • Chaturvedi, V.1    Collison, L.W.2    Guy, C.S.3    Workman, C.J.4    Vignali, D.A.5
  • 18
    • 78449296907 scopus 로고    scopus 로고
    • IL-35-mediated induction of a potent regulatory T cell population
    • Collison LW, Chaturvedi V, Henderson AL etal. IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol 2010; 11: 1093-1101.
    • (2010) Nat Immunol , vol.11 , pp. 1093-1101
    • Collison, L.W.1    Chaturvedi, V.2    Henderson, A.L.3
  • 19
    • 84863376362 scopus 로고    scopus 로고
    • IL-35 is a novel responsive anti-inflammatory cytokine - a new system of categorizing anti-inflammatory cytokines
    • Li X, Mai J, Virtue A etal. IL-35 is a novel responsive anti-inflammatory cytokine - a new system of categorizing anti-inflammatory cytokines. PLoS One 2012; 7: e33628.
    • (2012) PLoS One , vol.7 , pp. e33628
    • Li, X.1    Mai, J.2    Virtue, A.3
  • 20
    • 75149158969 scopus 로고    scopus 로고
    • Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC
    • Seyerl M, Kirchberger S, Majdic O etal. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. Eur J Immunol 2010; 40: 321-329.
    • (2010) Eur J Immunol , vol.40 , pp. 321-329
    • Seyerl, M.1    Kirchberger, S.2    Majdic, O.3
  • 22
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat Rev Immunol 2005; 5: 521-531.
    • (2005) Nat Rev Immunol , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 24
    • 34247523141 scopus 로고    scopus 로고
    • Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation
    • Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu Rev Immunol 2007; 25: 221-242.
    • (2007) Annu Rev Immunol , vol.25 , pp. 221-242
    • Kastelein, R.A.1    Hunter, C.A.2    Cua, D.J.3
  • 25
    • 84866555886 scopus 로고    scopus 로고
    • From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines
    • Banchereau J, Pascual V, O'Garra A. From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines. Nat Immunol 2012; 13: 925-931.
    • (2012) Nat Immunol , vol.13 , pp. 925-931
    • Banchereau, J.1    Pascual, V.2    O'Garra, A.3
  • 26
    • 55149126024 scopus 로고    scopus 로고
    • Regulation of immune responses by interleukin-27
    • Yoshida H, Miyazaki Y. Regulation of immune responses by interleukin-27. Immunol Rev 2008; 226: 234-247.
    • (2008) Immunol Rev , vol.226 , pp. 234-247
    • Yoshida, H.1    Miyazaki, Y.2
  • 27
    • 84897027520 scopus 로고    scopus 로고
    • IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
    • Shen P, Roch T, Lampropoulou V etal. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 2014; 507: 366-370.
    • (2014) Nature , vol.507 , pp. 366-370
    • Shen, P.1    Roch, T.2    Lampropoulou, V.3
  • 28
    • 84902078796 scopus 로고    scopus 로고
    • Interleukin-35 induces regulatory B cells that suppress autoimmune disease
    • Wang RX, Yu CR, Dambuza IM etal. Interleukin-35 induces regulatory B cells that suppress autoimmune disease. Nat Med 2014; 20: 633-641.
    • (2014) Nat Med , vol.20 , pp. 633-641
    • Wang, R.X.1    Yu, C.R.2    Dambuza, I.M.3
  • 29
    • 84902074573 scopus 로고    scopus 로고
    • Interleukin-35 takes the 'B' line
    • Mauri C, Nistala K. Interleukin-35 takes the 'B' line. Nat Med 2014; 20: 580-581.
    • (2014) Nat Med , vol.20 , pp. 580-581
    • Mauri, C.1    Nistala, K.2
  • 31
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 2005; 6: 1142-1151.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 32
    • 33847153417 scopus 로고    scopus 로고
    • Foxp3-dependent programme of regulatory T-cell differentiation
    • Gavin MA, Rasmussen JP, Fontenot JD etal. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 2007; 445: 771-775.
    • (2007) Nature , vol.445 , pp. 771-775
    • Gavin, M.A.1    Rasmussen, J.P.2    Fontenot, J.D.3
  • 33
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 34
    • 84862844377 scopus 로고    scopus 로고
    • The battle against immunopathology: infectious tolerance mediated by regulatory T cells
    • Gravano DM, Vignali DA. The battle against immunopathology: infectious tolerance mediated by regulatory T cells. Cell Mol Life Sci 2012; 69: 1997-2008.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 1997-2008
    • Gravano, D.M.1    Vignali, D.A.2
  • 35
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003; 3: 253-257.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 36
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: multiple varieties of T regulatory cells
    • Shevach EM. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 2006; 25: 195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 38
    • 78449306308 scopus 로고    scopus 로고
    • Regulatory ripples
    • Belkaid Y, Chen W. Regulatory ripples. Nat Immunol 2010; 11: 1077-1078.
    • (2010) Nat Immunol , vol.11 , pp. 1077-1078
    • Belkaid, Y.1    Chen, W.2
  • 40
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
    • Chen W, Jin W, Hardegen N etal. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J Exp Med 2003; 198: 1875-1886.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 41
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M etal. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737-742.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 42
    • 33644982044 scopus 로고    scopus 로고
    • Regulation of immune responses by T cells
    • Jiang H, Chess L. Regulation of immune responses by T cells. N Engl J Med 2006; 354: 1166-1176.
    • (2006) N Engl J Med , vol.354 , pp. 1166-1176
    • Jiang, H.1    Chess, L.2
  • 43
    • 84906316259 scopus 로고    scopus 로고
    • Utilizing regulatory T cells against rheumatoid arthritis
    • Haque M, Fino K, Lei F, Xiong X, Song J. Utilizing regulatory T cells against rheumatoid arthritis. Front Oncol 2014; 4: 209.
    • (2014) Front Oncol , vol.4 , pp. 209
    • Haque, M.1    Fino, K.2    Lei, F.3    Xiong, X.4    Song, J.5
  • 44
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R, Naghavi M, Foreman K etal. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095-2128.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 45
    • 59749096640 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Liaw YF, Chu CM. Hepatitis B virus infection. Lancet 2009; 373: 582-592.
    • (2009) Lancet , vol.373 , pp. 582-592
    • Liaw, Y.F.1    Chu, C.M.2
  • 46
    • 84919848147 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Trépo C, Chan HLY, Lok A. Hepatitis B virus infection. Lancet 2014; 384: 2053-2063.
    • (2014) Lancet , vol.384 , pp. 2053-2063
    • Trépo, C.1    Chan, H.L.Y.2    Lok, A.3
  • 47
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 2005; 5: 215-229.
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 48
    • 66149166191 scopus 로고    scopus 로고
    • Hepatitis B: the virus and disease
    • Liang TJ. Hepatitis B: the virus and disease. Hepatology 2009; 49 Suppl 5: S13-21.
    • (2009) Hepatology , vol.49 , pp. S13-S21
    • Liang, T.J.1
  • 50
    • 84868702241 scopus 로고    scopus 로고
    • Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
    • Bertoletti A, Ferrari C. Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection. Gut 2012; 61: 1754-1764.
    • (2012) Gut , vol.61 , pp. 1754-1764
    • Bertoletti, A.1    Ferrari, C.2
  • 51
    • 77957353047 scopus 로고    scopus 로고
    • The host-pathogen interaction during HBV infection: immunological controversies
    • Bertoletti A, Maini MK, Ferrari C. The host-pathogen interaction during HBV infection: immunological controversies. Antivir Ther 2010; 15 Suppl 3: 15-24.
    • (2010) Antivir Ther , vol.15 , pp. 15-24
    • Bertoletti, A.1    Maini, M.K.2    Ferrari, C.3
  • 52
    • 84860337613 scopus 로고    scopus 로고
    • New insight in the pathobiology of hepatitis B virus infection
    • Dandri M, Locarnini S. New insight in the pathobiology of hepatitis B virus infection. Gut 2012; 61 Suppl 1: i6-17.
    • (2012) Gut , vol.61 , pp. i6-17
    • Dandri, M.1    Locarnini, S.2
  • 53
    • 84922478778 scopus 로고    scopus 로고
    • Immunosuppression in patients with chronic hepatitis B
    • Seetharam A, Perrillo R, Gish R. Immunosuppression in patients with chronic hepatitis B. Curr Hepatol Rep 2014; 13: 235-244.
    • (2014) Curr Hepatol Rep , vol.13 , pp. 235-244
    • Seetharam, A.1    Perrillo, R.2    Gish, R.3
  • 55
    • 77953627758 scopus 로고    scopus 로고
    • IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10
    • Kochetkova I, Golden S, Holderness K, Callis G, Pascual DW. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J Immunol 2010; 184: 7144-7153.
    • (2010) J Immunol , vol.184 , pp. 7144-7153
    • Kochetkova, I.1    Golden, S.2    Holderness, K.3    Callis, G.4    Pascual, D.W.5
  • 57
    • 84907246279 scopus 로고    scopus 로고
    • The possible role of the novel cytokines IL-35 and IL-37 in inflammatory bowel disease
    • Li Y, Wang Y, Liu Y etal. The possible role of the novel cytokines IL-35 and IL-37 in inflammatory bowel disease. Mediators Inflamm 2014; 2014: 136329.
    • (2014) Mediators Inflamm , vol.2014 , pp. 136329
    • Li, Y.1    Wang, Y.2    Liu, Y.3
  • 58
    • 80054856034 scopus 로고    scopus 로고
    • Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis
    • Wirtz S, Billmeier U, McHedlidze T, Blumberg RS, Neurath MF. Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis. Gastroenterology 2011; 141: 1875-1886.
    • (2011) Gastroenterology , vol.141 , pp. 1875-1886
    • Wirtz, S.1    Billmeier, U.2    McHedlidze, T.3    Blumberg, R.S.4    Neurath, M.F.5
  • 59
    • 79960141235 scopus 로고    scopus 로고
    • Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2
    • Zandian M, Mott KR, Allen SJ, Dumitrascu O, Kuo JZ, Ghiasi H. Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2. Gene Ther 2011; 18: 734-742.
    • (2011) Gene Ther , vol.18 , pp. 734-742
    • Zandian, M.1    Mott, K.R.2    Allen, S.J.3    Dumitrascu, O.4    Kuo, J.Z.5    Ghiasi, H.6
  • 60
    • 84862297381 scopus 로고    scopus 로고
    • Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation
    • Bai J, Qiu SL, Zhong XN etal. Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. Mediators Inflamm 2012; 2012: 410232.
    • (2012) Mediators Inflamm , vol.2012 , pp. 410232
    • Bai, J.1    Qiu, S.L.2    Zhong, X.N.3
  • 61
    • 84861851646 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35
    • Bettini M, Castellaw AH, Lennon GP, Burton AR, Vignali DA. Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35. Diabetes 2012; 61: 1519-1526.
    • (2012) Diabetes , vol.61 , pp. 1519-1526
    • Bettini, M.1    Castellaw, A.H.2    Lennon, G.P.3    Burton, A.R.4    Vignali, D.A.5
  • 62
    • 84871391940 scopus 로고    scopus 로고
    • Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases
    • Lin Y, Huang Y, Lu Z etal. Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases. PLoS One 2012; 7: e52490.
    • (2012) PLoS One , vol.7 , pp. e52490
    • Lin, Y.1    Huang, Y.2    Lu, Z.3
  • 63
    • 84859387020 scopus 로고    scopus 로고
    • Increased Th17 and regulatory T cell responses in EBV-induced gene 3-deficient mice lead to marginally enhanced development of autoimmune encephalomyelitis
    • Liu JQ, Liu Z, Zhang X etal. Increased Th17 and regulatory T cell responses in EBV-induced gene 3-deficient mice lead to marginally enhanced development of autoimmune encephalomyelitis. J Immunol 2012; 188: 3099-3106.
    • (2012) J Immunol , vol.188 , pp. 3099-3106
    • Liu, J.Q.1    Liu, Z.2    Zhang, X.3
  • 64
    • 84871110517 scopus 로고    scopus 로고
    • Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade
    • Olson BM, Jankowska-Gan E, Becker JT, Vignali DA, Burlingham WJ, McNeel DG. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol 2012; 189: 5590-5601.
    • (2012) J Immunol , vol.189 , pp. 5590-5601
    • Olson, B.M.1    Jankowska-Gan, E.2    Becker, J.T.3    Vignali, D.A.4    Burlingham, W.J.5    McNeel, D.G.6
  • 65
    • 84885436263 scopus 로고    scopus 로고
    • IL-35: a potential target for the treatment of atherosclerosis
    • Huang Y, Lin YZ, Shi Y, Ji QW. IL-35: a potential target for the treatment of atherosclerosis. Pharmazie 2013; 68: 793-795.
    • (2013) Pharmazie , vol.68 , pp. 793-795
    • Huang, Y.1    Lin, Y.Z.2    Shi, Y.3    Ji, Q.W.4
  • 66
    • 84878586670 scopus 로고    scopus 로고
    • Human placental trophoblasts express the immunosuppressive cytokine IL-35
    • Mao H, Gao W, Ma C etal. Human placental trophoblasts express the immunosuppressive cytokine IL-35. Hum Immunol 2013; 74: 872-877.
    • (2013) Hum Immunol , vol.74 , pp. 872-877
    • Mao, H.1    Gao, W.2    Ma, C.3
  • 67
    • 84876406357 scopus 로고    scopus 로고
    • Possible roles of IL-12-family cytokines in rheumatoid arthritis
    • Pope RM, Shahrara S. Possible roles of IL-12-family cytokines in rheumatoid arthritis. Nat Rev Rheumatol 2013; 9: 252-256.
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 252-256
    • Pope, R.M.1    Shahrara, S.2
  • 68
    • 84892696404 scopus 로고    scopus 로고
    • Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27
    • Kochetkova I, Thornburg T, Callis G, Holderness K, Maddaloni M, Pascual DW. Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. J Immunol 2014; 192: 804-816.
    • (2014) J Immunol , vol.192 , pp. 804-816
    • Kochetkova, I.1    Thornburg, T.2    Callis, G.3    Holderness, K.4    Maddaloni, M.5    Pascual, D.W.6
  • 69
    • 84902195117 scopus 로고    scopus 로고
    • Interleukin-35 gene therapy exacerbates experimental rheumatoid arthritis in mice
    • Thiolat A, Denys A, Petit M etal. Interleukin-35 gene therapy exacerbates experimental rheumatoid arthritis in mice. Cytokine 2014; 69: 87-93.
    • (2014) Cytokine , vol.69 , pp. 87-93
    • Thiolat, A.1    Denys, A.2    Petit, M.3
  • 70
    • 84871707047 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis
    • Tirotta E, Duncker P, Oak J etal. Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis. J Neuroimmunol 2013; 254: 110-116.
    • (2013) J Neuroimmunol , vol.254 , pp. 110-116
    • Tirotta, E.1    Duncker, P.2    Oak, J.3
  • 71
    • 84885362636 scopus 로고    scopus 로고
    • Assessing the role of IL-35 in colorectal cancer progression and prognosis
    • Zeng JC, Zhang Z, Li TY etal. Assessing the role of IL-35 in colorectal cancer progression and prognosis. Int J Clin Exp Pathol 2013; 6: 1806-1816.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 1806-1816
    • Zeng, J.C.1    Zhang, Z.2    Li, T.Y.3
  • 72
    • 84925488303 scopus 로고    scopus 로고
    • Aberrant expression of regulatory cytokine IL-35 and pattern recognition receptor NOD2 in patients with allergic asthma
    • Epub ahead of print
    • Wong CK, Leung TF, Chu IM, Dong J, Lam YY, Lam CW. Aberrant expression of regulatory cytokine IL-35 and pattern recognition receptor NOD2 in patients with allergic asthma. Inflammation 2014. [Epub ahead of print].
    • (2014) Inflammation
    • Wong, C.K.1    Leung, T.F.2    Chu, I.M.3    Dong, J.4    Lam, Y.Y.5    Lam, C.W.6
  • 73
    • 84908261914 scopus 로고    scopus 로고
    • The expression of a novel anti-inflammatory cytokine IL-35 and its possible significance in childhood asthma
    • Ma Y, Liu X, Wei Z etal. The expression of a novel anti-inflammatory cytokine IL-35 and its possible significance in childhood asthma. Immunol Lett 2014; 162: 11-17.
    • (2014) Immunol Lett , vol.162 , pp. 11-17
    • Ma, Y.1    Liu, X.2    Wei, Z.3
  • 74
    • 84911901461 scopus 로고    scopus 로고
    • Decreased concentration of IL-35 in plasma of patients with asthma and COPD
    • Chen C, Deng Y, Chen H etal. Decreased concentration of IL-35 in plasma of patients with asthma and COPD. Asian Pac J Allergy Immunol 2014; 32: 211-217.
    • (2014) Asian Pac J Allergy Immunol , vol.32 , pp. 211-217
    • Chen, C.1    Deng, Y.2    Chen, H.3
  • 75
    • 84925869842 scopus 로고    scopus 로고
    • Circulating levels of interleukin-35 in patients with multiple sclerosis: evaluation of the influences of FOXP3 gene polymorphism and treatment program
    • Epub ahead of print
    • Jafarzadeh A, Jamali M, Mahdavi R etal. Circulating levels of interleukin-35 in patients with multiple sclerosis: evaluation of the influences of FOXP3 gene polymorphism and treatment program. J Mol Neurosci 2014 [Epub ahead of print].
    • (2014) J Mol Neurosci
    • Jafarzadeh, A.1    Jamali, M.2    Mahdavi, R.3
  • 76
    • 84890170920 scopus 로고    scopus 로고
    • Circulating IL-35 in pancreatic ductal adenocarcinoma patients
    • Jin P, Ren H, Sun W, Xin W, Zhang H, Hao J. Circulating IL-35 in pancreatic ductal adenocarcinoma patients. Hum Immunol 2014; 75: 29-33.
    • (2014) Hum Immunol , vol.75 , pp. 29-33
    • Jin, P.1    Ren, H.2    Sun, W.3    Xin, W.4    Zhang, H.5    Hao, J.6
  • 77
    • 84908390756 scopus 로고    scopus 로고
    • IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor
    • Nicholl MB, Ledgewood CL, Chen X etal. IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: Evidence for a role as an autocrine growth factor. Cytokine 2014; 70: 126-133.
    • (2014) Cytokine , vol.70 , pp. 126-133
    • Nicholl, M.B.1    Ledgewood, C.L.2    Chen, X.3
  • 78
    • 84899413645 scopus 로고    scopus 로고
    • Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells
    • Pan Y, Tao Q, Wang H etal. Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells. PLoS One 2014; 9: e93591.
    • (2014) PLoS One , vol.9 , pp. e93591
    • Pan, Y.1    Tao, Q.2    Wang, H.3
  • 79
    • 84892371343 scopus 로고    scopus 로고
    • The imbalanced profile and clinical significance of T helper associated cytokines in bone marrow microenvironment of the patients with acute myeloid leukemia
    • Sun YX, Kong HL, Liu CF etal. The imbalanced profile and clinical significance of T helper associated cytokines in bone marrow microenvironment of the patients with acute myeloid leukemia. Hum Immunol 2014; 75: 113-118.
    • (2014) Hum Immunol , vol.75 , pp. 113-118
    • Sun, Y.X.1    Kong, H.L.2    Liu, C.F.3
  • 80
    • 84855557634 scopus 로고    scopus 로고
    • Regulatory T-cell-associated cytokines in systemic lupus erythematosus
    • Okamoto A, Fujio K, Okamura T, Yamamoto K. Regulatory T-cell-associated cytokines in systemic lupus erythematosus. J Biomed Biotechnol 2011; 2011: 463412.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 463412
    • Okamoto, A.1    Fujio, K.2    Okamura, T.3    Yamamoto, K.4
  • 81
    • 77954895261 scopus 로고    scopus 로고
    • Core-specific adaptive regulatory T-cells in different outcomes of hepatitis C
    • Langhans B, Braunschweiger I, Arndt S etal. Core-specific adaptive regulatory T-cells in different outcomes of hepatitis C. Clin Sci (Lond) 2010; 119: 97-109.
    • (2010) Clin Sci (Lond) , vol.119 , pp. 97-109
    • Langhans, B.1    Braunschweiger, I.2    Arndt, S.3
  • 82
    • 79953030082 scopus 로고    scopus 로고
    • Detectable expression of IL-35 in CD4+ T cells from peripheral blood of chronic hepatitis B patients
    • Liu F, Tong F, He Y, Liu H. Detectable expression of IL-35 in CD4+ T cells from peripheral blood of chronic hepatitis B patients. Clin Immunol 2011; 139: 1-5.
    • (2011) Clin Immunol , vol.139 , pp. 1-5
    • Liu, F.1    Tong, F.2    He, Y.3    Liu, H.4
  • 83
    • 84873304654 scopus 로고    scopus 로고
    • Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice
    • Tsuda M, Zhang W, Yang GX etal. Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice. Hepatology 2013; 57: 806-816.
    • (2013) Hepatology , vol.57 , pp. 806-816
    • Tsuda, M.1    Zhang, W.2    Yang, G.X.3
  • 84
    • 84899558871 scopus 로고    scopus 로고
    • Effects of phased joint intervention on IL-35 and IL-17 expression levels in patients with portal hypertension
    • Wang Y, Dong J, Meng W etal. Effects of phased joint intervention on IL-35 and IL-17 expression levels in patients with portal hypertension. Int J Mol Med 2014; 33: 1131-1139.
    • (2014) Int J Mol Med , vol.33 , pp. 1131-1139
    • Wang, Y.1    Dong, J.2    Meng, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.