The possible role of the novel cytokines IL-35 and IL-37 in inflammatory bowel disease

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Li, Yanmei ^a   Wang, Yanan ^a   Liu, Ying ^a   Wang, Yatian ^a   Zuo, Xiuli ^a   Li, Yanqing ^a   Lu, Xuefeng ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 35; INTERLEUKIN 37; UNCLASSIFIED DRUG; IL37 PROTEIN, HUMAN; INTERLEUKIN 1; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, HUMAN;

ABDOMINAL PAIN; ADULT; ARTHRITIS; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; CROHN DISEASE ACTIVITY INDEX; DIARRHEA; DISEASE MARKER; DOUBLE BALLOON ENTEROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY BOWEL DISEASE; INTESTINE EPITHELIUM CELL; MALE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; ULCERATIVE COLITIS; WESTERN BLOTTING; ADOLESCENT; AGED; BLOOD; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-1; INTERLEUKINS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84907246279     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/136329     Document Type: Article

References (31)

1. Podolsky D. K., Inflammatory bowel disease. The New England Journal of Medicine 2002 347 6 417 429 10.1056/NEJMra020831 2-s2.0-0037043658
2. MacDonald T. T., Monteleone G., Immunity, inflammation, and allergy in the gut. Science 2005 307 5717 1920 1925 10.1126/science.1106442 2-s2.0-15544382565
3. Maloy K. J., Powrie F., Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011 474 7351 298 306 10.1038/nature10208 2-s2.0-79959271087
4. Collison L. W., Workman C. J., Kuo T. T., Boyd K., Wang Y., Vignali K. M., Cross R., Sehy D., Blumberg R. S., Vignali D. A. A., The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007 450 7169 566 569 10.1038/nature06306 2-s2.0-36549030784
5. Chaturvedi V., Collison L. W., Guy C. S., Workman C. J., Vignali D. A. A., Cutting edge: human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. Journal of Immunology 2011 186 12 6661 6666 10.4049/jimmunol.1100315 2-s2.0-79959572627
6. Shen P., Roch T., Lampropoulou V., IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 2014 507 7492 366 370
7. Li X., Mai J., Virtue A., Yin Y., Gong R., Sha X., Gutchigian S., Frisch A., Hodge I., Jiang X., Wang H., Yang X., IL-35 is a novel responsive anti-inflammatory cytokine-a new system of categorizing anti-inflammatory cytokines. PLoS ONE 2012 7 3 e33628 10.1371/journal.pone.0033628 2-s2.0-84863376362
8. Lee Y. K., Mazmanian S. K., Has the microbiota played a critical role in the evolution of the adaptive immune system? Science 2010 330 6012 1768 1773 10.1126/science.1195568 2-s2.0-78650647326
9. Chen P., Fang S., The expression of human antimicrobial peptide LL-37 in the human nasal mucosa. The American Journal of Rhinology 2004 18 6 381 385 2-s2.0-13844311085
10. D'Haens G., Sandborn W. J., Feagan B. G., Geboes K., Hanauer S. B., Irvine E. J., Lémann M., Marteau P., Rutgeerts P., Schölmerich J., Sutherland L. R., A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 2007 132 2 763 786 10.1053/j.gastro.2006.12.038 2-s2.0-33847179443
11. Harvey R. F., Bradshaw J. M., A simple index of Crohn's-disease activity. The Lancet 1980 1 8167 514 2-s2.0-0019319257
12. Takahashi M., Nakamura K., Honda K., Kitamura Y., Mizutani T., Araki Y., Kabemura T., Chijiiwa Y., Harada N., Nawata H., An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis. Digestive Diseases and Sciences 2006 51 4 677 686 10.1007/s10620-006-3191-2 2-s2.0-33645891652
13. Kumar S., Hanning C. R., Brigham-Burke M. R., Rieman D. J., Lehr R., Khandekar S., Kirkpatrick R. B., Scott G. F., Lee J. C., Lynch F. J., Gao W., Gambotto A., Lotze M. T., Interleukin-1F7b (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7b binds to the IL-18 receptor but does not induce IFN- γ production. Cytokine 2002 18 2 61 71 10.1006/cyto.2002.0873 2-s2.0-0036020218
14. Bufler P., Gamboni-Robertson F., Azam T., Kim S., Dinarello C. A., Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochemical Journal 2004 381 2 503 510 10.1042/BJ20040217 2-s2.0-3242790036
15. Yu Q. T., Saruta M., Avanesyan A., Fleshner P. R., Banham A. H., Papadakis K. A., Expression and functional characterization of FOXP3+CD4 + regulatory T cells in ulcerative colitis. Inflammatory Bowel Diseases 2007 13 2 191 199 10.1002/ibd.20053 2-s2.0-34249309861
16. Bufler P., Azam T., Gamboni-Robertson F., Reznikov L. L., Kumar S., Dinarello C. A., Kim S., A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proceedings of the National Academy of Sciences of the United States of America 2002 99 21 13723 13728 10.1073/pnas.212519099 2-s2.0-0037109051
17. Sharma S., Kulk N., Nold M. F., Gräf R., Kim S., Reinhardt D., Dinarello C. A., Bufler P., The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. Journal of Immunology 2008 180 8 5477 5482 10.4049/jimmunol.180.8.5477 2-s2.0-45949111754
18. Zandian M., Mott K. R., Allen S. J., Dumitrascu O., Kuo J. Z., Ghiasi H., Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2. Gene Therapy 2011 18 7 734 742 10.1038/gt.2011.32 2-s2.0-79960141235
19. +regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. Journal of Immunology 2010 184 12 7144 7153 10.4049/jimmunol.0902739 2-s2.0-77953627758
20. Whitehead G. S., Wilson R. H., Nakano K., Burch L. H., Nakano H., Cook D. N., IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. Journal of Allergy and Clinical Immunology 2012 129 1 207 215 10.1016/j.jaci.2011.08.009 2-s2.0-84455199735
21. Wirtz S., Billmeier U., McHedlidze T., Blumberg R. S., Neurath M. F., Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis. Gastroenterology 2011 141 5 1875 1886 10.1053/j.gastro.2011.07.040 2-s2.0-80054856034
22. Devergne O., Birkenbach M., Kieff E., Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proceedings of the National Academy of Sciences of the United States of America 1997 94 22 12041 12046 10.1073/pnas.94.22.12041 2-s2.0-0030700003
23. Yang J., Yang M., Htut T. M., Ouyang X., Hanidu A., Li X., Sellati R., Jiang H., Zhang S., Li H., Zhao J., Ting A. T., Mayer L., Unkeless J. C., Labadia M. E., Hodge M., Li J., Xiong H., Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and ROR γ t. European Journal of Immunology 2008 38 5 1204 1214 10.1002/eji.200838145 2-s2.0-47049114262
24. Frank G. M., Divito S. J., Maker D. M., Xu M., Hendricks R. L., A novel P40-independent function of IL-12P35 is required for progression and maintenance of herpes stromal keratitis. Investigative Ophthalmology and Visual Science 2010 51 7 3591 3598 10.1167/iovs.09-4368 2-s2.0-77955868238
25. Ye S., Wu J., Zhou L., Lv Z., Xie H., Zheng S., Interleukin-35: the future of hyperimmune -related diseases? Journal of Interferon and Cytokine Research 2013 33 6 285 291 10.1089/jir.2012.0086 2-s2.0-84878537521
26. Collison L. W., Delgoffe G. M., Guy C. S., Vignali K. M., Chaturvedi V., Fairweather D., Satoskar A. R., Garcia K. C., Hunter C. A., Drake C. G., Murray P. J., Vignali D. A. A., The composition and signaling of the IL-35 receptor are unconventional. Nature Immunology 2012 13 3 290 299 10.1038/ni.2227 2-s2.0-84857193362
27. Nold M. F., Nold-Petry C. A., Zepp J. A., Palmer B. E., Bufler P., Dinarello C. A., IL-37 is a fundamental inhibitor of innate immunity. Nature Immunology 2010 11 11 1014 1022 10.1038/ni.1944 2-s2.0-77958149102
28. Boraschi D., Lucchesi D., Hainzl S., Leitner M., Maier E., Mangelberger D., Oostingh G. J., Pfaller T., Pixner C., Posselt G., Italiani P., Nold M. F., Nold-Petry C. A., Bufler P., Dinarello C. A., IL-37: A new anti-inflammatory cytokine of the IL-1 family. European Cytokine Network 2011 22 3 127 147 10.1684/ecn.2011.0288 2-s2.0-83055163376
29. de Smet K., Contreras R., Human antimicrobial peptides: defensins, cathelicidins and histatins. Biotechnology Letters 2005 27 18 1337 1347 10.1007/s10529-005-0936-5 2-s2.0-29144521244
30. Liu M., Guo S., Hibbert J. M., Jain V., Singh N., Wilson N. O., Stiles J. K., CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications. Cytokine and Growth Factor Reviews 2011 22 3 121 130 10.1016/j.cytogfr.2011.06.001 2-s2.0-80052314034
31. Imaeda H., Takahashi K., Fujimoto T., Kasumi E., Ban H., Bamba S., Sonoda H., Shimizu T., Fujiyama Y., Andoh A., Epithelial expression of interleukin-37b in inflammatory bowel disease. Clinical and Experimental Immunology 2013 172 3 410 416 10.1111/cei.12061 2-s2.0-84876732950