IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

European Journal of Immunology

Volumn 37, Issue 11, 2007, Pages 3021-3029

  Niedbala, Wanda ^a,b   Wei, Xiao Qing ^a,c   Cai, Beilei ^a   Hueber, Axel J ^a   Leung, Bernard P ^d   McInnes, Iain B ^a   Liew, Foo Y ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b INSTITUTE OF HUMAN GENETICS   (Poland)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Arthritis; Cytokines; IL 35; Regulatory T cells; Th17 cells

Indexed keywords

CD28 ANTIGEN; CD3 ANTIBODY; COLLAGEN; CYTOKINE; GAMMA INTERFERON; HETERODIMER; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 35; INTERLEUKIN 4; PROTEIN P35; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTHRITIS; ARTICLE; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; EFFECTOR CELL; EPSTEIN BARR VIRUS INDUCED GENE 3; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE CULTURE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REGULATORY T LYMPHOCYTE; TH17 CELL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMANS; INTERLEUKIN-12 SUBUNIT P35; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 36248970671     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737810     Document Type: Article

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