Internal motions prime cIAP1 for rapid activation

Nature Structural and Molecular Biology

Volumn 21, Issue 12, 2014, Pages 1068-1074

  Phillips, Aaron H ^a,c   Schoeffler, Allyn J ^a   Matsui, Tsutomu ^b   Weiss, Thomas M ^b   Blankenship, John W ^a,d   Zobel, Kerry ^a   Giannetti, Anthony M ^a   Dueber, Erin C ^a   Fairbrother, Wayne J ^a  

^a GENENTECH INC   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d Emergent Biosolutions   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF APOPTOSIS PROTEIN 1; MONOMER; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; BIRC2 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CARBON NUCLEAR MAGNETIC RESONANCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; GEL PERMEATION CHROMATOGRAPHY; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; MOLECULAR MODEL; NITROGEN NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; KINETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; X RAY DIFFRACTION;

HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SCATTERING, SMALL ANGLE; UBIQUITIN; UBIQUITIN-ACTIVATING ENZYMES; X-RAY DIFFRACTION;

EID: 84925552884     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2916     Document Type: Article

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