-
1
-
-
79961032414
-
Liver ischemia and reperfusion injury: New insights into mechanisms of innate-Adaptive immune-mediated tissue inflammation
-
Zhai Y, Busuttil RW, Kupiec-Weglinski JW. Liver ischemia and reperfusion injury: new insights into mechanisms of innate-Adaptive immune-mediated tissue inflammation. Am J Transplant 2011; 11: 1563.
-
(2011)
Am J Transplant
, vol.11
, pp. 1563
-
-
Zhai, Y.1
Busuttil, R.W.2
Kupiec-Weglinski, J.W.3
-
2
-
-
10344264453
-
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway
-
Zhai Y, Shen XD, O'Connell R, et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol 2004; 173: 7115.
-
(2004)
J Immunol
, vol.173
, pp. 7115
-
-
Zhai, Y.1
Shen, X.D.2
O'Connell, R.3
-
3
-
-
28244489599
-
Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells
-
Tsung A, Hoffman RA, Izuishi K, et al. Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J Immunol 2005; 175: 7661.
-
(2005)
J Immunol
, vol.175
, pp. 7661
-
-
Tsung, A.1
Hoffman, R.A.2
Izuishi, K.3
-
4
-
-
0042330074
-
Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: Reassessment of the ARE consensus sequence
-
Nioi P, McMahonM, Itoh K, et al. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: Reassessment of the ARE consensus sequence. Biochem J 2003; 374(Pt 2): 337.
-
(2003)
Biochem J
, vol.374
, pp. 337
-
-
Nioi, P.1
McMahon, M.2
Itoh, K.3
-
5
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M, Itoh K, Yamamoto M, et al. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem 2003; 278: 21592.
-
(2003)
J Biol Chem
, vol.278
, pp. 21592
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
-
6
-
-
67449168081
-
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice
-
Reddy NM, Kleeberger SR, Kensler TW, et al. Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice. J Immunol 2009; 182: 7264.
-
(2009)
J Immunol
, vol.182
, pp. 7264
-
-
Reddy, N.M.1
Kleeberger, S.R.2
Kensler, T.W.3
-
7
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
-
Lee JM, Calkins MJ, Chan K, et al. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J Biol Chem 2003; 278: 12029.
-
(2003)
J Biol Chem
, vol.278
, pp. 12029
-
-
Lee, J.M.1
Calkins, M.J.2
Chan, K.3
-
8
-
-
70350115341
-
Nrf2 protects against maladaptive cardiac responses to hemodynamic stress
-
Li J, Ichikawa T, Villacorta L, et al. Nrf2 protects against maladaptive cardiac responses to hemodynamic stress. Arterioscler Thromb Vasc Biol 2009; 29: 1843.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1843
-
-
Li, J.1
Ichikawa, T.2
Villacorta, L.3
-
9
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili D, Arden KC. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 2004; 117: 421.
-
(2004)
Cell
, vol.117
, pp. 421
-
-
Accili, D.1
Arden, K.C.2
-
10
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005; 24: 7410.
-
(2005)
Oncogene
, vol.24
, pp. 7410
-
-
Greer, E.L.1
Brunet, A.2
-
11
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96: 857.
-
(1999)
Cell
, vol.96
, pp. 857
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
-
12
-
-
0033560896
-
Direct control of the Forkhead transcription factor AFX by protein kinase B
-
Kops GJ, de Ruiter ND, De Vries-Smits AM, et al. Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 1999; 398: 630.
-
(1999)
Nature
, vol.398
, pp. 630
-
-
Kops, G.J.1
De Ruiter, N.D.2
De Vries-Smits, A.M.3
-
13
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
-
Ramaswamy S, Nakamura N, Sansal I, et al. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2002; 2: 81.
-
(2002)
Cancer Cell
, vol.2
, pp. 81
-
-
Ramaswamy, S.1
Nakamura, N.2
Sansal, I.3
-
14
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002; 419: 316.
-
(2002)
Nature
, vol.419
, pp. 316
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
-
15
-
-
41449088342
-
Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors
-
Evans-Anderson HJ, Alfieri CM, Yutzey KE. Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors. Circ Res 2008; 102: 686.
-
(2008)
Circ Res
, vol.102
, pp. 686
-
-
Evans-Anderson, H.J.1
Alfieri, C.M.2
Yutzey, K.E.3
-
16
-
-
79953186624
-
FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress
-
Sengupta A, Molkentin JD, Paik JH, et al. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J Biol Chem 2011; 286: 7468.
-
(2011)
J Biol Chem
, vol.286
, pp. 7468
-
-
Sengupta, A.1
Molkentin, J.D.2
Paik, J.H.3
-
17
-
-
84873549572
-
FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells
-
Seiler F, Hellberg J, Lepper PM, et al. FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells. J Immunol 2013; 190: 1603.
-
(2013)
J Immunol
, vol.190
, pp. 1603
-
-
Seiler, F.1
Hellberg, J.2
Lepper, P.M.3
-
18
-
-
0036677208
-
CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection
-
Shen XD, Ke B, Zhai Y, et al. CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection. Transplantation 2002; 74: 315.
-
(2002)
Transplantation
, vol.74
, pp. 315
-
-
Shen, X.D.1
Ke, B.2
Zhai, Y.3
-
19
-
-
33845655925
-
Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin
-
Shan Y, Lambrecht RW, Donohue SE, et al. Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin. FASEB J 2006; 20: 2651.
-
(2006)
FASEB J
, vol.20
, pp. 2651
-
-
Shan, Y.1
Lambrecht, R.W.2
Donohue, S.E.3
-
20
-
-
70350539525
-
FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages
-
Su D, Coudriet GM, Hyun Kim D, et al. FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages. Diabetes 2009; 58: 2624.
-
(2009)
Diabetes
, vol.58
, pp. 2624
-
-
Su, D.1
Coudriet, G.M.2
Hyun, K.D.3
-
21
-
-
84872140886
-
PTEN-mediated Akt/beta-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury
-
Kamo N, Ke B, Busuttil RW, et al. PTEN-mediated Akt/beta-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury. Hepatology 2013; 57: 289.
-
(2013)
Hepatology
, vol.57
, pp. 289
-
-
Kamo, N.1
Ke, B.2
Busuttil, R.W.3
-
22
-
-
84887997385
-
KEAP1-NRF2 complex in ischemiainduced hepatocellular damage of mouse liver transplants
-
Ke B, Shen XD, Zhang Y, et al. KEAP1-NRF2 complex in ischemiainduced hepatocellular damage of mouse liver transplants. J Hepatol 2013; 59: 1200.
-
(2013)
J Hepatol
, vol.59
, pp. 1200
-
-
Ke, B.1
Shen, X.D.2
Zhang, Y.3
-
23
-
-
41849150779
-
FOXOs, cancer and regulation of apoptosis
-
Fu Z, Tindall DJ. FOXOs, cancer and regulation of apoptosis. Oncogene 2008; 27: 2312.
-
(2008)
Oncogene
, vol.27
, pp. 2312
-
-
Fu, Z.1
Tindall, D.J.2
-
24
-
-
0036629251
-
Cell cycle and death control: Long live Forkheads
-
Burgering BM, Kops GJ. Cell cycle and death control: long live Forkheads. Trends Biochem Sci 2002; 27: 352.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 352
-
-
Burgering, B.M.1
Kops, G.J.2
-
25
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2: 675.
-
(2001)
Nat Immunol
, vol.2
, pp. 675
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
26
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West AP, Brodsky IE, Rahner C, et al. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011; 472: 476.
-
(2011)
Nature
, vol.472
, pp. 476
-
-
West, A.P.1
Brodsky, I.E.2
Rahner, C.3
-
28
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K, Chiba T, Takahashi S, et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 1997; 236: 313.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
-
29
-
-
84882236393
-
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease
-
Ruiz S, Pergola PE, Zager RA, et al. Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease. Kidney Int 2013; 83: 1029.
-
(2013)
Kidney Int
, vol.83
, pp. 1029
-
-
Ruiz, S.1
Pergola, P.E.2
Zager, R.A.3
-
30
-
-
70449723401
-
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice
-
Reddy NM, Suryanarayana V, Kalvakolanu DV, et al. Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice. J Immunol 2009; 183: 4601.
-
(2009)
J Immunol
, vol.183
, pp. 4601
-
-
Reddy, N.M.1
Suryanarayana, V.2
Kalvakolanu, D.V.3
-
31
-
-
77956193657
-
NADPH oxidasedependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice
-
Kong X, Thimmulappa R, Kombairaju P, et al. NADPH oxidasedependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice. J Immunol 2010; 185: 569.
-
(2010)
J Immunol
, vol.185
, pp. 569
-
-
Kong, X.1
Thimmulappa, R.2
Kombairaju, P.3
-
32
-
-
66049098514
-
Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFNbeta production
-
Tzima S, Victoratos P, Kranidioti K, et al. Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFNbeta production. J Exp Med 2009; 206: 1167.
-
(2009)
J Exp Med
, vol.206
, pp. 1167
-
-
Tzima, S.1
Victoratos, P.2
Kranidioti, K.3
-
33
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
Alam J, Stewart D, Touchard C, et al. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem 1999; 274: 26071.
-
(1999)
J Biol Chem
, vol.274
, pp. 26071
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
-
35
-
-
84866890498
-
The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)/NRF2 signaling pathway and cytokine release
-
Cai C, Teng L, Vu D, et al. The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)/NRF2 signaling pathway and cytokine release. J Biol Chem 2012; 287: 33720.
-
(2012)
J Biol Chem
, vol.287
, pp. 33720
-
-
Cai, C.1
Teng, L.2
Vu, D.3
-
36
-
-
75149154705
-
FOXO-dependent regulation of innate immune homeostasis
-
Becker T, Loch G, Beyer M, et al. FOXO-dependent regulation of innate immune homeostasis. Nature 2010; 463: 369.
-
(2010)
Nature
, vol.463
, pp. 369
-
-
Becker, T.1
Loch, G.2
Beyer, M.3
-
37
-
-
80054713581
-
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis
-
Kong X, Thimmulappa R, Craciun F, et al. Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. Am J Respir Crit Care Med 2011; 184: 928.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 928
-
-
Kong, X.1
Thimmulappa, R.2
Craciun, F.3
-
38
-
-
84895910708
-
Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-kappaB-mediated inflammatory response
-
Jiang T, Tian F, Zheng H, et al. Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-kappaB-mediated inflammatory response. Kidney Int 2013; 85: 333.
-
(2013)
Kidney Int
, vol.85
, pp. 333
-
-
Jiang, T.1
Tian, F.2
Zheng, H.3
-
39
-
-
1642471831
-
PI3K/Akt and apoptosis: Size matters
-
Franke TF, Hornik CP, Segev L, et al. PI3K/Akt and apoptosis: Size matters. Oncogene 2003; 22: 8983.
-
(2003)
Oncogene
, vol.22
, pp. 8983
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
-
40
-
-
78650266432
-
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
-
Fan W, Morinaga H, Kim JJ, et al. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J 2010; 29: 4223.
-
(2010)
EMBO J
, vol.29
, pp. 4223
-
-
Fan, W.1
Morinaga, H.2
Kim, J.J.3
-
41
-
-
84902262307
-
Nrf2 activation protects the liver from ischemia/reperfusion injury in mice
-
Kudoh K, Uchinami H, Yoshioka M, et al. Nrf2 activation protects the liver from ischemia/reperfusion injury in mice. Ann Surg 2013; 260: 118.
-
(2013)
Ann Surg
, vol.260
, pp. 118
-
-
Kudoh, K.1
Uchinami, H.2
Yoshioka, M.3
-
42
-
-
84905911897
-
Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell cycle control and apoptosis
-
Kohler UA, Kurinna S, Schwitter D, et al. Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell cycle control and apoptosis. Hepatology 2013.
-
(2013)
Hepatology
-
-
Kohler, U.A.1
Kurinna, S.2
Schwitter, D.3
-
43
-
-
0027319824
-
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine
-
Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, et al. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 1993; 55: 1265.
-
(1993)
Transplantation
, vol.55
, pp. 1265
-
-
Suzuki, S.1
Toledo-Pereyra, L.H.2
Rodriguez, F.J.3
-
44
-
-
84855958437
-
HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling
-
Ke B, Shen XD, Ji H, et al. HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling. J Hepatol 2012; 56: 359.
-
(2012)
J Hepatol
, vol.56
, pp. 359
-
-
Ke, B.1
Shen, X.D.2
Ji, H.3
|