KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

Journal of Hepatology

Volumn 59, Issue 6, 2013, Pages 1200-1207

  Ke, Bibo ^a   Shen, Xiu Da ^a   Zhang, Yu ^a   Ji, Haofeng ^a   Gao, Feng ^a   Yue, Shi ^a   Kamo, Naoko ^a   Zhai, Yuan ^a   Yamamoto, Masayuki ^b   Busuttil, Ronald W ^a   Kupiec Weglinski, Jerzy W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

HO 1; Keap1 Nrf2 redox system; Liver ischemia reperfusion injury; Liver transplantation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALANINE AMINOTRANSFERASE; CASPASE 3; CHLORDANE; CXCL1 CHEMOKINE; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LACTATE DEHYDROGENASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; THIOREDOXIN REDUCTASE 1; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL DAMAGE; LIVER GRAFT; LIVER ISCHEMIA; LIVER NECROSIS; LIVER PROTECTION; LIVER TRANSPLANTATION; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION;

ANTI-OXIDANT RESPONSE ELEMENT; ARE; H(2)O(2); HEME-OXYGENASE-1; HEPATOCYTE KNOCKOUT; HIF-1; HKO; HO-1; HRE; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR-1; HYPOXIA RESPONSE ELEMENT; IRI; ISCHEMIA/REPERFUSION INJURY; KEAP1; KEAP1-NRF2 REDOX SYSTEM; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LACTATE DEHYDROGENASE; LDH; LIVER ISCHEMIA/REPERFUSION INJURY; LIVER TRANSPLANTATION; NRF2; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2; OLT; ORTHOTOPIC LIVER TRANSPLANTATION; PHOSPHOINOSITIDE 3-KINASE; PI3K; SALT; SERUM ALANINE AMINOTRANSFERASE; TERMINAL DEOXYRIBONUCLEOTIDYL TRANSFERASE (TDT)-MEDIATED DUTP-DIGOXIGENIN NICK END LABELING; THIOREDOXIN 1; TRX1; TUNEL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOSKELETAL PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER; LIVER TRANSPLANTATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; NF-E2-RELATED FACTOR 2; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84887997385     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.07.016     Document Type: Article

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