Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 15, 2013, Pages 4472-4476

  Pan, Peiwen ^a   Vermelho, Alane Beatriz ^b   Scozzafava, Andrea ^c   Parkkila, Seppo ^a   Capasso, Clemente ^d   Supuran, Claudiu T ^c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c UNIVERSITY OF FLORENCE   (Italy)

^d INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

Author keywords

Alpha class enzyme; Anion; Carbonic anhydrase; Inhibitor; Trypanosoma cruzi

Indexed keywords

ANTITRYPANOSOMAL AGENT; ARSONIC ACID; BENZENEBORONIC ACID; BENZNIDAZOLE; CARBONATE DEHYDRATASE; CYANIC ACID; DIETHYLDITHIOCARBAMIC ACID; HYDROGENSULFIDE; IODIDE; NIFURTIMOX; SULFAMIC ACID; SULFANILAMIDE; THIOCYANATE; TRITHIOCARBONATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHAGAS DISEASE; DRUG BINDING; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; LIFE CYCLE; NONHUMAN; TRYPANOSOMA CRUZI;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 84879686974     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.05.058     Document Type: Article

References (41)

1. V. Alterio, A. Di Fiore, K. D'Ambrosio, C.T. Supuran, and G. De Simone Chem. Rev. 112 2012 4421
2. J.F. Domsic, B.S. Avvaru, C.U. Kim, S.M. Gruner, M. Agbandje-McKenna, D.N. Silverman, and R. McKenna J. Biol. Chem. 283 2008 30766
3. C.T. Supuran Nature Rev. Drug Discov. 7 2008 168
4. C.T. Supuran Front. Pharmacol. 2 2011 34
5. B.C. Tripp, C.B. Bell, F. Cruz III, Krebs C., and J.G.J. Ferry Biol. Chem. 279 2004 6683
6. Y. Xu, L. Feng, P.D. Jeffrey, Y. Shi, and F.M. Morel Nature 452 2008 56
7. V. Alterio, M. Hilvo, A. Di Fiore, C.T. Supuran, P. Pan, S. Parkkila, A. Scaloni, J. Pastorek, S. Pastorekova, C. Pedone, A. Scozzafava, S.M. Monti, and G. De Simone Proc. Natl. Acad. Sci. USA 106 2009 16233
8. D. Neri, and C.T. Supuran Nature Rev. Drug Discov. 10 2011 767
9. C. Schlicker, R.A. Hall, D. Vullo, S. Middelhaufe, M. Gertz, C.T. Supuran, F.A. Muhlschlegel, and C. Steegborn J. Mol. Biol. 385 2009 1207
10. A. Suarez Covarrubias, A.M. Larsson, M. Hogbom, J. Lindberg, T. Bergfors, C. Bjorkelid, S.L. Mowbray, T. Unge, and T.A. Jones J. Biol. Chem. 280 2005 18782
11. C. Tu, B.C. Tripp, J.G. Ferry, and D.N. Silverman J. Am. Chem. Soc. 123 2001 5861
12. A.S. Covarrubias, T. Bergfors, T.A. Jones, and M. Hogbom J. Biol. Chem. 281 2006 4993
13. C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 3467
14. P. Burghout, D. Vullo, A. Scozzafava, P.W. Hermans, and C.T. Supuran Med. Chem. 19 2011 243
15. P. Joseph, S. Ouahrani-Bettache, J.L. Montero, I. Nishimori, T. Minakuchi, D. Vullo, A. Scozzafava, J.Y. Winum, S. Kohler, and C.T. Supuran Med. Chem. 19 2011 1172
16. P. Joseph, F. Turtaut, S. Ouahrani-Bettache, J.L. Montero, I. Nishimori, T. Minakuchi, D. Vullo, A. Scozzafava, S. Kohler, J.Y. Winum, and C.T. Supuran J. Med. Chem. 53 2010 2277
17. I. Nishimori, T. Minakuchi, K. Morimoto, S. Sano, S. Onishi, H. Takeuchi, D. Vullo, A. Scozzafava, and C.T. Supuran J. Med. Chem. 49 2006 2117
18. I. Nishimori, T. Minakuchi, D. Vullo, A. Scozzafava, A. Innocenti, and C.T. Supuran J. Med. Chem. 52 2009 3116
19. C.T. Supuran Curr. Pharm. Des. 16 2010 3233
20. C.T. Supuran, A. Scozzafava, and A. Casini Med. Res. Rev. 23 2003 146
21. D. Vullo, I. Nishimori, A. Scozzafava, S. Kohler, J.Y. Winum, and C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 2178
22. J.Y. Winum, S. Kohler, and C.T. Supuran Curr. Pharm. Des. 16 2010 3310
23. J. Krungkrai, S.R. Krungkrai, and C.T. Supuran Curr. Top. Med. Chem. 7 2007 909
24. J. Krungkrai, S.R. Krungkrai, and C.T. Supuran Bioorg. Med. Chem. Lett. 18 2008 5466
25. J. Krungkrai, and C.T. Supuran Curr. Pharm. Des. 14 2008 631
26. P. Pan, A.B. Vermelho, G. Capaci Rodrigues, A. Scozzafava, M.E. Tolvanen, S. Parkkila, C. Capasso, and C.T. Supuran J. Med. Chem. 56 2013 1761
27. G. De Simone, and C.T. Supuran J. Inorg. Biochem. 111 2012 117
28. R.G. Khalifah J. Biol. Chem. 246 1971 2561
29. A. Innocenti, A. Scozzafava, and C.T. Supuran Bioorg. Med. Chem. Lett. 2009 1855 19
30. A. Innocenti, A. Scozzafava, and C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 1548
31. S. Kolayli, F. Karahalil, H. Sahin, B. Dincer, and C.T. Supuran J. Enzyme Inhib Med. Chem. 26 2011 895
32. A. Maresca, A. Scozzafava, S. Kohler, J.Y. Winum, and C.T. Supuran J. Inorg. Biochem. 110 2012 36
33. O. Ozensoy, M. Arslan, and C.T. Supuran J. Enzyme Inhib Med. Chem. 26 2011 749
34. C. Temperini, A. Scozzafava, and C.T. Supuran Bioorg. Med. Chem. Lett. 20 2010 474
35. S. Del Prete, S. Isik, D. Vullo, V. De Luca, V. Carginale, A. Scozzafava, C.T. Supuran, and C. Capasso J. Med. Chem. 55 2012 10742
36. C. Capasso, and C.T. Supuran Expert Opin. Ther. Pat. 23 2013 693
37. A. Ohradanova, D. Vullo, S. Pastorekova, J. Pastorek, D.J. Jackson, G. Worheide, and C.T. Supuran Bioorg. Med. Chem. 20 2012 1403
38. F. Carta, M. Aggarwal, A. Maresca, A. Scozzafava, R. McKenna, and C.T. Supuran Chem. Commun. 2012 1868 48
39. A. Maresca, F. Carta, D. Vullo, and C.T. Supuran J. Enzyme Inhib Med. Chem. 28 2013 407
40. F. Carta, M. Aggarwal, A. Maresca, A. Scozzafava, R. McKenna, E. Masini, and C.T. Supuran J. Med. Chem. 55 2012 1721
41. C.T. Supuran J. Enzyme Inhib Med. Chem. 27 2012 759 Superior Tecnológico Pesquisa do Estado do Rio de Janeiro