A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 14, 2013, Pages 4067-4071

  Del Prete, Sonia ^a   Vullo, Daniela ^b   De Luca, Viviana ^b   Carginale, Vincenzo ^a   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b   Capasso, Clemente ^a  

^a INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Anion; Carbonic anhydrase; Dithiocarbamate; Gamma class enzyme; Periodontitis; Porphyromonas gingivalis

Indexed keywords

AZIDE; BENZENEBORONIC ACID; CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARBONIC ACID DERIVATIVE; CYANIDE; DIETHYLDITHIOCARBAMIC ACID; HYDROGEN SULFIDE; SULFANILAMIDE; SULFUR ACID DERIVATIVE; THIOCYANATE;

ARTICLE; BACTERIAL VIRULENCE; CATALYST; CONCENTRATION RESPONSE; CRYPTOCOCCUS NEOFORMANS; ENZYME INHIBITION; HYDRATION; MICHAELIS MENTEN KINETICS; MOLECULE; NONHUMAN; OPEN READING FRAME; PERIODONTITIS; PORPHYROMONAS GINGIVALIS;

AMINO ACID SEQUENCE; ANIONS; BIOCATALYSIS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PORPHYROMONAS GINGIVALIS; PROTEIN ISOFORMS; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); METHANOSARCINA THERMOPHILA; PORPHYROMONAS GINGIVALIS;

EID: 84879412113     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.05.063     Document Type: Article

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