-
1
-
-
0034733910
-
Sphingosine-1-phosphate: signaling inside and out
-
COI: 1:CAS:528:DC%2BD3cXktlKqsbs%3D, PID: 10878250
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: signaling inside and out. FEBS Lett. 2000;476(1–2):55–7.
-
(2000)
FEBS Lett
, vol.476
, Issue.1-2
, pp. 55-57
-
-
Spiegel, S.1
Milstien, S.2
-
2
-
-
4344706187
-
The ins and outs of lysophosphatidic acid signaling
-
COI: 1:CAS:528:DC%2BD2cXnt1CqtLg%3D, PID: 15273989
-
Moolenaar WH, van Meeteren LA, Giepmans BN. The ins and outs of lysophosphatidic acid signaling. Bioessays. 2004;26(8):870–81. doi:10.1002/bies.20081.
-
(2004)
Bioessays
, vol.26
, Issue.8
, pp. 870-881
-
-
Moolenaar, W.H.1
van Meeteren, L.A.2
Giepmans, B.N.3
-
3
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein coupled receptor EDG-1
-
COI: 1:CAS:528:DyaK1cXhs1Kls7s%3D, PID: 9488656
-
Lee MJ, Van Brocklyn JR, Thangada S, Liu CH, Hand AR, Menzeleev R, et al. Sphingosine-1-phosphate as a ligand for the G protein coupled receptor EDG-1. Science. 1998;279(5356):1552–5.
-
(1998)
Science
, vol.279
, Issue.5356
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
-
4
-
-
0030829750
-
Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids
-
COI: 1:CAS:528:DyaK2sXnt1ektL8%3D, PID: 9409733
-
An S, Bleu T, Huang W, Hallmark OG, Coughlin SR, Goetzl EJ. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. FEBS Lett. 1997;417(3):279–82.
-
(1997)
FEBS Lett
, vol.417
, Issue.3
, pp. 279-282
-
-
An, S.1
Bleu, T.2
Huang, W.3
Hallmark, O.G.4
Coughlin, S.R.5
Goetzl, E.J.6
-
5
-
-
0032031519
-
Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1
-
COI: 1:CAS:528:DyaK1cXit1Kns7c%3D, PID: 9480864
-
Zondag GC, Postma FR, Etten IV, Verlaan I, Moolenaar WH. Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochem J. 1998;330(2):605–9.
-
(1998)
Biochem J
, vol.330
, Issue.2
, pp. 605-609
-
-
Zondag, G.C.1
Postma, F.R.2
Etten, I.V.3
Verlaan, I.4
Moolenaar, W.H.5
-
6
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
COI: 1:CAS:528:DC%2BD38XjtVWhsrc%3D, PID: 11923495
-
Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science. 2002;296(5566):346–9. doi:10.1126/science.1070238.
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
-
7
-
-
0033053652
-
Sphingosine 1-phosphate: a prototype of a new class of second messengers
-
COI: 1:CAS:528:DyaK1MXhslSqsbs%3D, PID: 10080537
-
Spiegel S. Sphingosine 1-phosphate: a prototype of a new class of second messengers. J Leukoc Biol. 1999;65(3):341–4.
-
(1999)
J Leukoc Biol
, vol.65
, Issue.3
, pp. 341-344
-
-
Spiegel, S.1
-
8
-
-
0033604620
-
Bioactive lysophospholipids and their G protein-coupled receptors
-
COI: 1:CAS:528:DyaK1MXnsF2it7c%3D, PID: 10579925
-
Moolenaar WH. Bioactive lysophospholipids and their G protein-coupled receptors. Exp Cell Res. 1999;253(1):230–8.
-
(1999)
Exp Cell Res
, vol.253
, Issue.1
, pp. 230-238
-
-
Moolenaar, W.H.1
-
9
-
-
0032245902
-
Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles
-
COI: 1:CAS:528:DyaK1cXmtF2qtr4%3D, PID: 9821862
-
Igarashi Y, Yatomi Y. Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. Acta Biochim Pol. 1998;45(2):299–309.
-
(1998)
Acta Biochim Pol
, vol.45
, Issue.2
, pp. 299-309
-
-
Igarashi, Y.1
Yatomi, Y.2
-
10
-
-
0033566338
-
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
-
COI: 1:CAS:528:DyaK1MXjvF2qu7k%3D, PID: 10423159
-
Hla T, Lee MJ, Ancellin N, Liu CH, Thangada S, Thompson BD, et al. Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? Biochem Pharmacol. 1999;58(2):201–7.
-
(1999)
Biochem Pharmacol
, vol.58
, Issue.2
, pp. 201-207
-
-
Hla, T.1
Lee, M.J.2
Ancellin, N.3
Liu, C.H.4
Thangada, S.5
Thompson, B.D.6
-
11
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
-
COI: 1:CAS:528:DC%2BD1MXhtVOmsrjJ, PID: 19729656
-
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, et al. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science. 2009;325(5945):1254–7. doi:10.1126/science.1176709.
-
(2009)
Science
, vol.325
, Issue.5945
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
Singh, S.K.6
-
12
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
COI: 1:CAS:528:DC%2BC3cXnvFSgs7s%3D, PID: 20577214
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, et al. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature. 2010;465(7301):1084–8. doi:10.1038/nature09128.
-
(2010)
Nature
, vol.465
, Issue.7301
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
-
13
-
-
0032429270
-
Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate
-
An SZ, Goetz EJ, Lee HY. Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate. J Cell Biochem. 1998;147–57.
-
(1998)
J Cell Biochem
, pp. 147-157
-
-
An, S.Z.1
Goetz, E.J.2
Lee, H.Y.3
-
14
-
-
0036266101
-
International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature
-
COI: 1:CAS:528:DC%2BD38XltVOiu7Y%3D, PID: 12037142
-
Chun J, Goetzl EJ, Hla T, Igarashi Y, Lynch KR, Moolenaar W, et al. International union of pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev. 2002;54(2):265–9.
-
(2002)
Pharmacol Rev
, vol.54
, Issue.2
, pp. 265-269
-
-
Chun, J.1
Goetzl, E.J.2
Hla, T.3
Igarashi, Y.4
Lynch, K.R.5
Moolenaar, W.6
-
15
-
-
0033615537
-
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
-
COI: 1:CAS:528:DyaK1MXnt1Gqs7o%3D, PID: 10555146
-
Lee MJ, Thangada S, Claffey KP, Ancellin N, Liu CH, Kluk M, et al. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell. 1999;99(3):301–12.
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 301-312
-
-
Lee, M.J.1
Thangada, S.2
Claffey, K.P.3
Ancellin, N.4
Liu, C.H.5
Kluk, M.6
-
16
-
-
57649194902
-
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells
-
COI: 1:CAS:528:DC%2BD1cXht1yntLzM, PID: 18765664
-
Estrada R, Zeng Q, Lu H, Sarojini H, Lee JF, Mathis SP, et al. Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. J Biol Chem. 2008;283(44):30363–75. doi:10.1074/jbc.M804392200.
-
(2008)
J Biol Chem
, vol.283
, Issue.44
, pp. 30363-30375
-
-
Estrada, R.1
Zeng, Q.2
Lu, H.3
Sarojini, H.4
Lee, J.F.5
Mathis, S.P.6
-
17
-
-
40749117727
-
Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells
-
COI: 1:CAS:528:DC%2BD1cXotlKgtA%3D%3D, PID: 18209079
-
Eskan MA, Rose BG, Benakanakere MR, Lee MJ, Kinane DF. Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells. J Immunol. 2008;180(3):1818–25.
-
(2008)
J Immunol
, vol.180
, Issue.3
, pp. 1818-1825
-
-
Eskan, M.A.1
Rose, B.G.2
Benakanakere, M.R.3
Lee, M.J.4
Kinane, D.F.5
-
18
-
-
84860293201
-
Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells
-
COI: 1:CAS:528:DC%2BC38XmtlGlur4%3D, PID: 22344462
-
Hsu A, Zhang W, Lee JF, An J, Ekambaram P, Liu J, et al. Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. Int J Oncol. 2012;40(5):1619–26. doi:10.3892/ijo.2012.1379.
-
(2012)
Int J Oncol
, vol.40
, Issue.5
, pp. 1619-1626
-
-
Hsu, A.1
Zhang, W.2
Lee, J.F.3
An, J.4
Ekambaram, P.5
Liu, J.6
-
19
-
-
84887467273
-
ETS-1-mediated transcriptional up-regulation of CD44 is required for sphingosine-1-phosphate receptor subtype 3-stimulated chemotaxis
-
COI: 1:CAS:528:DC%2BC3sXhslCnu7vL, PID: 24064218, This study characterized a novel ETS-1/CD44 pathway in S1P-stimulated chemotaxis
-
Zhang W, Zhao J, Lee JF, Gartung A, Jawadi H, Lambiv WL, et al. ETS-1-mediated transcriptional up-regulation of CD44 is required for sphingosine-1-phosphate receptor subtype 3-stimulated chemotaxis. J Biol Chem. 2013;288(45):32126–37. doi:10.1074/jbc.M113.495218. This study characterized a novel ETS-1/CD44 pathway in S1P-stimulated chemotaxis.
-
(2013)
J Biol Chem
, vol.288
, Issue.45
, pp. 32126-32137
-
-
Zhang, W.1
Zhao, J.2
Lee, J.F.3
Gartung, A.4
Jawadi, H.5
Lambiv, W.L.6
-
20
-
-
17944363486
-
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis
-
COI: 1:CAS:528:DC%2BD3MXnslGmt7o%3D, PID: 11583630
-
Lee MJ, Thangada S, Paik JH, Sapkota GP, Ancellin N, Chae SS, et al. Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol Cell. 2001;8(3):693–704.
-
(2001)
Mol Cell
, vol.8
, Issue.3
, pp. 693-704
-
-
Lee, M.J.1
Thangada, S.2
Paik, J.H.3
Sapkota, G.P.4
Ancellin, N.5
Chae, S.S.6
-
21
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
COI: 1:CAS:528:DC%2BD3cXnsVeisbw%3D, PID: 11032855
-
Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J Clin Invest. 2000;106(8):951–61. doi:10.1172/jci10905.
-
(2000)
J Clin Invest
, vol.106
, Issue.8
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
Hobson, J.P.6
-
22
-
-
0034799675
-
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
-
COI: 1:CAS:528:DC%2BD3MXmsFKrtLo%3D, PID: 11544274
-
Garcia JG, Liu F, Verin AD, Birukova A, Dechert MA, Gerthoffer WT, et al. Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J Clin Invest. 2001;108(5):689–701. doi:10.1172/jci12450.
-
(2001)
J Clin Invest
, vol.108
, Issue.5
, pp. 689-701
-
-
Garcia, J.G.1
Liu, F.2
Verin, A.D.3
Birukova, A.4
Dechert, M.A.5
Gerthoffer, W.T.6
-
23
-
-
84888874884
-
Sphingosine-1-phosphate receptor-2 mediated NFkappaB activation contributes to tumor necrosis factor-alpha induced VCAM-1 and ICAM-1 expression in endothelial cells
-
COI: 1:CAS:528:DC%2BC3sXhtVWgurzI, PID: 23770055, S1PR2 plays a key role in endothelial inflammation
-
Zhang W, An J, Jawadi H, Siow DL, Lee JF, Zhao J, et al. Sphingosine-1-phosphate receptor-2 mediated NFkappaB activation contributes to tumor necrosis factor-alpha induced VCAM-1 and ICAM-1 expression in endothelial cells. Prostaglandins Other Lipid Mediat. 2013;106:62–71. doi:10.1016/j.prostaglandins.2013.06.001. S1PR2 plays a key role in endothelial inflammation.
-
(2013)
Prostaglandins Other Lipid Mediat
, vol.106
, pp. 62-71
-
-
Zhang, W.1
An, J.2
Jawadi, H.3
Siow, D.L.4
Lee, J.F.5
Zhao, J.6
-
24
-
-
17344394207
-
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival
-
PID: 9660876
-
Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A, Edsall L, Cuvillier O, et al. Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol. 1998;142(1):229–40.
-
(1998)
J Cell Biol
, vol.142
, Issue.1
, pp. 229-240
-
-
Van Brocklyn, J.R.1
Lee, M.J.2
Menzeleev, R.3
Olivera, A.4
Edsall, L.5
Cuvillier, O.6
-
25
-
-
0029977136
-
The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway
-
COI: 1:CAS:528:DyaK28XivV2isL8%3D, PID: 8626678
-
Lee MJ, Evans M, Hla T. The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway. J Biol Chem. 1996;271(19):11272–9.
-
(1996)
J Biol Chem
, vol.271
, Issue.19
, pp. 11272-11279
-
-
Lee, M.J.1
Evans, M.2
Hla, T.3
-
26
-
-
0025311299
-
An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
-
COI: 1:CAS:528:DyaK3cXlvVykurc%3D, PID: 2160972
-
Hla T, Maciag T. An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J Biol Chem. 1990;265(16):9308–13.
-
(1990)
J Biol Chem
, vol.265
, Issue.16
, pp. 9308-9313
-
-
Hla, T.1
Maciag, T.2
-
27
-
-
0034974903
-
Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity
-
COI: 1:CAS:528:DC%2BD3MXltVWhsbc%3D, PID: 11415936
-
Liu F, Verin AD, Wang P, Day R, Wersto RP, Chrest FJ, et al. Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. Am J Respir Cell Mol Biol. 2001;24(6):711–9.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, Issue.6
, pp. 711-719
-
-
Liu, F.1
Verin, A.D.2
Wang, P.3
Day, R.4
Wersto, R.P.5
Chrest, F.J.6
-
28
-
-
0035853689
-
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins
-
COI: 1:CAS:528:DC%2BD3MXjtFylsLo%3D, PID: 11150298
-
Paik JH, Chae S, Lee MJ, Thangada S, Hla T. Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. J Biol Chem. 2001;276(15):11830–7. doi:10.1074/jbc.M009422200.
-
(2001)
J Biol Chem
, vol.276
, Issue.15
, pp. 11830-11837
-
-
Paik, J.H.1
Chae, S.2
Lee, M.J.3
Thangada, S.4
Hla, T.5
-
29
-
-
0035374461
-
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells
-
COI: 1:CAS:528:DC%2BD3MXkt12rtbg%3D, PID: 11278592
-
Morales-Ruiz M, Lee MJ, Zollner S, Gratton JP, Scotland R, Shiojima I, et al. Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J Biol Chem. 2001;276(22):19672–7. doi:10.1074/jbc.M009993200.
-
(2001)
J Biol Chem
, vol.276
, Issue.22
, pp. 19672-19677
-
-
Morales-Ruiz, M.1
Lee, M.J.2
Zollner, S.3
Gratton, J.P.4
Scotland, R.5
Shiojima, I.6
-
30
-
-
33749350938
-
Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity
-
COI: 1:CAS:528:DC%2BD28XpvFams7c%3D, PID: 16891661
-
Lee JF, Zeng Q, Ozaki H, Wang L, Hand AR, Hla T, et al. Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. J Biol Chem. 2006;281(39):29190–200. doi:10.1074/jbc.M604310200.
-
(2006)
J Biol Chem
, vol.281
, Issue.39
, pp. 29190-29200
-
-
Lee, J.F.1
Zeng, Q.2
Ozaki, H.3
Wang, L.4
Hand, A.R.5
Hla, T.6
-
31
-
-
33747307276
-
Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells
-
COI: 1:CAS:528:DC%2BD28XotFKmtb8%3D, PID: 16416022
-
Lee JF, Ozaki H, Zhan X, Wang E, Hla T, Lee MJ. Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. Histochem Cell Biol. 2006;126(3):297–304. doi:10.1007/s00418-006-0143-z.
-
(2006)
Histochem Cell Biol
, vol.126
, Issue.3
, pp. 297-304
-
-
Lee, J.F.1
Ozaki, H.2
Zhan, X.3
Wang, E.4
Hla, T.5
Lee, M.J.6
-
32
-
-
42449085294
-
Rho GTPases mediated integrin alpha v beta 3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cells
-
COI: 1:CAS:528:DC%2BD1cXkvVSiur8%3D, PID: 18247041
-
Wang L, Lee JF, Lin CY, Lee MJ. Rho GTPases mediated integrin alpha v beta 3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cells. Histochem Cell Biol. 2008;129(5):579–88. doi:10.1007/s00418-008-0389-8.
-
(2008)
Histochem Cell Biol
, vol.129
, Issue.5
, pp. 579-588
-
-
Wang, L.1
Lee, J.F.2
Lin, C.Y.3
Lee, M.J.4
-
33
-
-
79957925060
-
Engagement of S1P(1)-degradative mechanisms leads to vascular leak in mice
-
COI: 1:CAS:528:DC%2BC3MXnsVaisbk%3D, PID: 21555855, This study used an animal model to show the role of S1PR1 in maintaining vascular permeability
-
Oo ML, Chang SH, Thangada S, Wu MT, Rezaul K, Blaho V, et al. Engagement of S1P(1)-degradative mechanisms leads to vascular leak in mice. J Clin Invest. 2011;121(6):2290–300. doi:10.1172/jci45403. This study used an animal model to show the role of S1PR1 in maintaining vascular permeability.
-
(2011)
J Clin Invest
, vol.121
, Issue.6
, pp. 2290-2300
-
-
Oo, M.L.1
Chang, S.H.2
Thangada, S.3
Wu, M.T.4
Rezaul, K.5
Blaho, V.6
-
34
-
-
58149483374
-
Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature
-
COI: 1:CAS:528:DC%2BD1MXhtVOiu78%3D, PID: 19011048
-
Lee JF, Gordon S, Estrada R, Wang L, Siow DL, Wattenberg BW, et al. Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. Am J Physiol Heart Circ Physiol. 2009;296(1):H33–42. doi:10.1152/ajpheart.00097.2008.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
, Issue.1
, pp. H33-H42
-
-
Lee, J.F.1
Gordon, S.2
Estrada, R.3
Wang, L.4
Siow, D.L.5
Wattenberg, B.W.6
-
35
-
-
0037370012
-
Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
-
COI: 1:CAS:528:DC%2BD3sXhs1Shu7k%3D, PID: 12588974
-
Sugimoto N, Takuwa N, Okamoto H, Sakurada S, Takuwa Y. Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform. Mol Cell Biol. 2003;23(5):1534–45.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.5
, pp. 1534-1545
-
-
Sugimoto, N.1
Takuwa, N.2
Okamoto, H.3
Sakurada, S.4
Takuwa, Y.5
-
36
-
-
34249280944
-
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
-
COI: 1:CAS:528:DC%2BD2sXltl2iu78%3D, PID: 17431187
-
Sanchez T, Skoura A, Wu MT, Casserly B, Harrington EO, Hla T. Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler Thromb Vasc Biol. 2007;27(6):1312–8. doi:10.1161/atvbaha.107.143735.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, Issue.6
, pp. 1312-1318
-
-
Sanchez, T.1
Skoura, A.2
Wu, M.T.3
Casserly, B.4
Harrington, E.O.5
Hla, T.6
-
38
-
-
0037007075
-
Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction
-
COI: 1:CAS:528:DC%2BD38XjtlCmtLg%3D, PID: 11927518
-
Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation. 2002;105(13):1541–4.
-
(2002)
Circulation
, vol.105
, Issue.13
, pp. 1541-1544
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Ishida, Y.4
Yoshida, H.5
Komuro, I.6
-
39
-
-
1042298050
-
Vascular cell senescence and vascular aging
-
COI: 1:CAS:528:DC%2BD2cXhtVOlsLk%3D, PID: 14871544
-
Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, Komuro I. Vascular cell senescence and vascular aging. J Mol Cell Cardiol. 2004;36(2):175–83. doi:10.1016/j.yjmcc.2003.11.010.
-
(2004)
J Mol Cell Cardiol
, vol.36
, Issue.2
, pp. 175-183
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Tateno, K.4
Kunieda, T.5
Komuro, I.6
-
40
-
-
84864708402
-
Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis
-
COI: 1:CAS:528:DC%2BC38XhtFGhtrfM, PID: 22753194, This study identified SIRT1 being a target of CDK5, and characterized the critical role of CDK5/SIRT1 signaling axis in endothelial senescence and atherosclerosis
-
Bai B, Liang Y, Xu C, Lee MY, Xu A, Wu D, et al. Cyclin-dependent kinase 5-mediated hyperphosphorylation of sirtuin-1 contributes to the development of endothelial senescence and atherosclerosis. Circulation. 2012;126(6):729–40. doi:10.1161/circulationaha.112.118778. This study identified SIRT1 being a target of CDK5, and characterized the critical role of CDK5/SIRT1 signaling axis in endothelial senescence and atherosclerosis.
-
(2012)
Circulation
, vol.126
, Issue.6
, pp. 729-740
-
-
Bai, B.1
Liang, Y.2
Xu, C.3
Lee, M.Y.4
Xu, A.5
Wu, D.6
-
41
-
-
0035130153
-
Differential expression of thymosin β-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis
-
COI: 1:CAS:528:DC%2BD3MXhsFemsrs%3D, PID: 11156961
-
VASILE E, TOMITA Y, BROWN LF, KOCHER O, DVORAK HF. Differential expression of thymosin β-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB J. 2001;15(2):458–66. doi:10.1096/fj.00-0051com.
-
(2001)
FASEB J
, vol.15
, Issue.2
, pp. 458-466
-
-
VASILE, E.1
TOMITA, Y.2
BROWN, L.F.3
KOCHER, O.4
DVORAK, H.F.5
-
42
-
-
78650866759
-
Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis
-
COI: 1:CAS:528:DC%2BC3cXhsFGrurvN, PID: 20947824, This study demonstrated that S1PR2 signaling in myeloid cells plays a key role in atherosclerosis
-
Skoura A, Michaud J, Im DS, Thangada S, Xiong Y, Smith JD, et al. Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol. 2011;31(1):81–5. doi:10.1161/atvbaha.110.213496. This study demonstrated that S1PR2 signaling in myeloid cells plays a key role in atherosclerosis.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, Issue.1
, pp. 81-85
-
-
Skoura, A.1
Michaud, J.2
Im, D.S.3
Thangada, S.4
Xiong, Y.5
Smith, J.D.6
-
43
-
-
0034834895
-
Endothelial cellular response to altered shear stress
-
COI: 1:CAS:528:DC%2BD3MXmvFCntLs%3D, PID: 11504676
-
Fisher AB, Chien S, Barakat AI, Nerem RM. Endothelial cellular response to altered shear stress. Am J Physiol Lung Cell Mol Physiol. 2001;281(3):L529–33.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.281
, Issue.3
, pp. L529-L533
-
-
Fisher, A.B.1
Chien, S.2
Barakat, A.I.3
Nerem, R.M.4
-
44
-
-
23444452042
-
Molecular basis of the effects of shear stress on vascular endothelial cells
-
PID: 16084198
-
Li Y-SJ, Haga JH, Chien S. Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech. 2005;38(10):1949–71.
-
(2005)
J Biomech
, vol.38
, Issue.10
, pp. 1949-1971
-
-
Li, Y.-S.J.1
Haga, J.H.2
Chien, S.3
-
45
-
-
79954457969
-
Endothelial cell culture model for replication of physiological profiles of pressure, flow, stretch, and shear stress in vitro
-
PID: 21413699, null-null
-
Estrada R, Giridharan GA, Nguyen M-D, Roussel TJ, Shakeri M, Parichehreh V. Endothelial cell culture model for replication of physiological profiles of pressure, flow, stretch, and shear stress in vitro. Anal Chem. 2011. doi:10.1021/ac2002998. null-null.
-
(2011)
Anal Chem
-
-
Estrada, R.1
Giridharan, G.A.2
Nguyen, M.-D.3
Roussel, T.J.4
Shakeri, M.5
Parichehreh, V.6
-
47
-
-
80053439792
-
Microfluidic endothelial cell culture model to replicate disturbed flow conditions seen in atherosclerosis susceptible regions
-
Estrada R, Giridharan GA, Nguyen M-D, Prabhu SD, Sethu P. Microfluidic endothelial cell culture model to replicate disturbed flow conditions seen in atherosclerosis susceptible regions. Biomicrofluidics. 2011;5(3):032006–11.
-
(2011)
Biomicrofluidics
, vol.5
, Issue.3
, pp. 032006-032011
-
-
Estrada, R.1
Giridharan, G.A.2
Nguyen, M.-D.3
Prabhu, S.D.4
Sethu, P.5
-
48
-
-
0031944478
-
Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1
-
COI: 1:CAS:528:DyaK1cXitFeqtLw%3D, PID: 9528783
-
Cantwell CA, Sterneck E, Johnson PF. Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1. Mol Cell Biol. 1998;18(4):2108–17.
-
(1998)
Mol Cell Biol
, vol.18
, Issue.4
, pp. 2108-2117
-
-
Cantwell, C.A.1
Sterneck, E.2
Johnson, P.F.3
-
49
-
-
84898601092
-
Inflammation and atherosclerosis: a review of the role of interleukin-6 in the development of atherosclerosis and the potential for targeted drug therapy
-
PID: 24618929
-
Hartman J, Frishman WH. Inflammation and atherosclerosis: a review of the role of interleukin-6 in the development of atherosclerosis and the potential for targeted drug therapy. Cardiol Rev. 2014;22(3):147–51. doi:10.1097/crd.0000000000000021.
-
(2014)
Cardiol Rev
, vol.22
, Issue.3
, pp. 147-151
-
-
Hartman, J.1
Frishman, W.H.2
-
50
-
-
84891881346
-
The gateway theory: how regional neural activation creates a gateway for immune cells via an inflammation amplifier
-
PID: 24385068
-
Ogura H, Arima Y, Kamimura D, Murakami M. The gateway theory: how regional neural activation creates a gateway for immune cells via an inflammation amplifier. Biomed J. 2013;36(6):269–73. doi:10.4103/2319-4170.113187.
-
(2013)
Biomed J
, vol.36
, Issue.6
, pp. 269-273
-
-
Ogura, H.1
Arima, Y.2
Kamimura, D.3
Murakami, M.4
-
51
-
-
84895996306
-
Atherosclerosis, dyslipidemia, and inflammation: the significant role of polyunsaturated fatty acids
-
PID: 24049656
-
Dessi M, Noce A, Bertucci P, di Villahermosa MS, Zenobi R, Castagnola V, et al. Atherosclerosis, dyslipidemia, and inflammation: the significant role of polyunsaturated fatty acids. ISRN Inflamm. 2013;2013:191823. doi:10.1155/2013/191823.
-
(2013)
ISRN Inflamm
, vol.2013
, pp. 191823
-
-
Dessi, M.1
Noce, A.2
Bertucci, P.3
di Villahermosa, M.S.4
Zenobi, R.5
Castagnola, V.6
-
52
-
-
84904343398
-
Sphingolipids affect fibrinogen-induced caveolar transcytosis and cerebrovascular permeability
-
COI: 1:CAS:528:DC%2BC2cXht1ygsbrE, PID: 24829496, This study demonstrated a novel role of sphingolipids in fibrinogen-mediated caveolar transcytosis, leading to increase cerebrovascular permeability
-
Muradashvili N, Khundmiri SJ, Tyagi R, Gartung A, Dean WL, Lee MJ, et al. Sphingolipids affect fibrinogen-induced caveolar transcytosis and cerebrovascular permeability. Am J Physiol Cell Physiol. 2014;307(2):C169–79. doi:10.1152/ajpcell.00305.2013. This study demonstrated a novel role of sphingolipids in fibrinogen-mediated caveolar transcytosis, leading to increase cerebrovascular permeability.
-
(2014)
Am J Physiol Cell Physiol
, vol.307
, Issue.2
, pp. C169-C179
-
-
Muradashvili, N.1
Khundmiri, S.J.2
Tyagi, R.3
Gartung, A.4
Dean, W.L.5
Lee, M.J.6
-
53
-
-
84911164049
-
Adipocyte lipolysis stimulated interleukin-6 production requires sphingosine kinase 1 activity
-
Sep 24. pii: jbc.M114.601096. [Epub ahead of print]
-
Zhang W, Mottillo EP, Zhao J, Gartung A, VanHecke GC, Lee JF, et al. Adipocyte lipolysis stimulated interleukin-6 production requires sphingosine kinase 1 activity. J Biol Chem. 2014. doi:10.1074/jbc.M114.601096. Sep 24. pii: jbc.M114.601096. [Epub ahead of print].
-
(2014)
J Biol Chem
-
-
Zhang, W.1
Mottillo, E.P.2
Zhao, J.3
Gartung, A.4
VanHecke, G.C.5
Lee, J.F.6
-
54
-
-
0022003324
-
Variation in susceptibility to atherosclerosis among inbred strains of mice
-
COI: 1:STN:280:DyaL28%2FnslWrtw%3D%3D, PID: 3841001
-
Paigen B, Morrow A, Brandon C, Mitchell D, Holmes P. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis. 1985;57(1):65–73.
-
(1985)
Atherosclerosis
, vol.57
, Issue.1
, pp. 65-73
-
-
Paigen, B.1
Morrow, A.2
Brandon, C.3
Mitchell, D.4
Holmes, P.5
-
55
-
-
84859157103
-
Role of sphingosine kinase localization in sphingolipid signaling
-
PID: 21537471
-
Wattenberg BW. Role of sphingosine kinase localization in sphingolipid signaling. World J Biol Chem. 2010;1(12):362–8. doi:10.4331/wjbc.v1.i12.362.
-
(2010)
World J Biol Chem
, vol.1
, Issue.12
, pp. 362-368
-
-
Wattenberg, B.W.1
-
56
-
-
84863009089
-
The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death
-
PID: 22613819
-
Van Brocklyn JR, Williams JB. The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death. Comp Biochem Physiol B Biochem Mol Biol. 2012;163(1):26–36. doi:10.1016/j.cbpb.2012.05.006.
-
(2012)
Comp Biochem Physiol B Biochem Mol Biol
, vol.163
, Issue.1
, pp. 26-36
-
-
Van Brocklyn, J.R.1
Williams, J.B.2
-
57
-
-
0037680229
-
Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism
-
COI: 1:CAS:528:DC%2BD3sXktVyisbc%3D, PID: 12782147
-
Hanada K. Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. Biochim Biophys Acta. 2003;1632(1–3):16–30.
-
(2003)
Biochim Biophys Acta
, vol.1632
, Issue.1-3
, pp. 16-30
-
-
Hanada, K.1
-
58
-
-
0035212942
-
Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption
-
COI: 1:CAS:528:DC%2BD3MXpt1Crtr8%3D, PID: 11709083
-
Linn SC, Kim HS, Keane EM, Andras LM, Wang E, Merrill Jr AH. Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption. Biochem Soc Trans. 2001;29(Pt 6):831–5.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 831-835
-
-
Linn, S.C.1
Kim, H.S.2
Keane, E.M.3
Andras, L.M.4
Wang, E.5
Merrill, A.H.6
-
59
-
-
39749145196
-
Translating molecular discoveries into new therapies for atherosclerosis
-
COI: 1:CAS:528:DC%2BD1cXit1ynsLc%3D, PID: 18288179
-
Rader DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature. 2008;451(7181):904–13. doi:10.1038/nature06796.
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 904-913
-
-
Rader, D.J.1
Daugherty, A.2
-
60
-
-
84924802834
-
National Institute for Health and Clinical Excellence May 2008
-
Lipid modification—cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease—quick reference guide. National Institute for Health and Clinical Excellence May 2008, reissued March 2010.
-
(2010)
reissued
-
-
-
61
-
-
79952052016
-
Statins for the primary prevention of cardiovascular disease
-
PID: 21249663, Online
-
Taylor F, Ward K, Moore TH, Burke M, Davey Smith G, Casas JP, et al. Statins for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2011;1, CD004816. doi:10.1002/14651858.CD004816.pub4. Online.
-
(2011)
Cochrane Database Syst Rev
, vol.1
-
-
Taylor, F.1
Ward, K.2
Moore, T.H.3
Burke, M.4
Davey Smith, G.5
Casas, J.P.6
-
62
-
-
84884474355
-
Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials
-
Naci H, Brugts J, Ades T. Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials. Circ Cardiovasc Qual Outcome. 2013;6(4):390–9. doi:10.1161/circoutcomes.111.000071.
-
(2013)
Circ Cardiovasc Qual Outcome
, vol.6
, Issue.4
, pp. 390-399
-
-
Naci, H.1
Brugts, J.2
Ades, T.3
-
63
-
-
79955400711
-
Statin-induced myopathy: a review and update
-
COI: 1:CAS:528:DC%2BC3MXltVGltbc%3D, PID: 21342078
-
Abd TT, Jacobson TA. Statin-induced myopathy: a review and update. Expert Opin Drug Saf. 2011;10(3):373–87. doi:10.1517/14740338.2011.540568.
-
(2011)
Expert Opin Drug Saf
, vol.10
, Issue.3
, pp. 373-387
-
-
Abd, T.T.1
Jacobson, T.A.2
|