Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles

Acta Biochimica Polonica

Volumn 45, Issue 2, 1998, Pages 299-309

  Igarashi, Yasuyuki ^a,c   Yatomi, Yutaka ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF YAMANASHI   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Intercellular messenger; Platelet activation; Platelet corrected count increment; Platelet transfusion reaction; Sphingosine 1 phosphate; Thrombosis

Indexed keywords

DRUG DERIVATIVE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE;

ANIMAL; AUTOCRINE EFFECT; BLOOD; HUMAN; MOUSE; PHYSIOLOGY; REVIEW; THROMBOCYTE; THROMBOCYTE ACTIVATION;

ANIMALS; AUTOCRINE COMMUNICATION; BLOOD PLATELETS; HUMANS; LYSOPHOSPHOLIPIDS; MICE; PLATELET ACTIVATION; SPHINGOSINE;

EID: 0032245902     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.1998_4226     Document Type: Review

References (29)

1. Spiegel, S., Foster, D. & Kolesnick, R. (1996) Signal transduction through lipid second messengers. Curr. Opin. Cell Biol. 8, 159-167.
2. Spiegel, S. & Milstien, S. (1995) Sphingolipid metabolites: Members of a new class of lipid second messengers. J. Membr. Biol. 146, 225-237.
3. Van Veldhoven, P.P. & Mannaerts, G.P. (1991) Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver. J. Biol. Chem. 266, 12502-12507.
4. Zhang, H., Desai, N.N., Olivera, A., Seki, T., Brooker, G. & Spiegel, S. (1991) Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 114, 155-167.
5. Olivera, A. & Spiegel, S. (1993) Sphingosine-1-phosphate as messenger in cell proliferation induced by PDGF and FCS mitogens. Nature (London) 365, 557-560.
6. Sadahira, Y., Ruan, F., Hakomori, S. & Igarashi, Y. (1992) Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. Proc. Natl. Acad. Sci. U.S.A. 89, 9686-9690.
7. Bornfeldt, K.E., Graves, L.M., Raines, E.W., Igarashi, Y., Wayman, G., Yamamura, S., Yatomi, Y., Sidhu, J.S., Krebs, E.G., Hakomori, S. & Ross, R. (1995) Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol. 130, 193-206.
8. + current in guinea-pig atrial myocytes by sphingosine-1-phosphate. J. Physiol. 489, 701-707.
9. van Koppen, C.J., Meyer zu Heringdorf, D., Laser, K.T., Zhang, C., Jakobs, K.H., Bunemann, M. & Pott, L. (1996) Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate. J. Biol. Chem. 271, 2082-2087.
10. Postma, F.R., Jalink, K., Hengeveld, T. & Moolenaar, W.H. (1996) Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. EMBO J. 15, 2388-2395.
11. Choi, O.H., Kim, J.-H. & Kinet, J.-P. (1996) Calcium mobilization via sphingosine kinase in signaling by the FcεRI antigen receptor Nature (London) 380, 634-636.
12. Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P.G., Coso, O.A., Gutkind, J.S. & Spiegel, S. (1996) Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature (London) 381, 800-803.
13. Yatomi, Y., Ruan, F., Hakomori, S. & Igarashi, Y. (1995) Sphingosine-1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood 86, 193-202.
14. Yatomi, Y., Ruan, F., Ohta, H., Welch, R.J., Hakomori, S. & Igarashi, Y. (1995) Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride. Anal. Biochem. 230, 315-320.
15. Yatomi, Y., Yamamura, S., Ruan, F. & Igarashi, Y. (1997) Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. J. Biol. Chem. 272, 5291-5297.
16. Stoffel, W., Heimann, G. & Hellenbroich, B. (1973) Sphingosine kinase in blood platelets. Hoppe-Seyler's Z. Physiol. Chem. 354, 562-566.
17. Stoffel, W., Hellenbroich, B. & Heimann, G. (1973) Properties and specificity of sphingosine kinase from blood platelets. Hoppe-Seyler's Z. Physiol. Chem. 354, 1311-1316.
18. Buehrer, B.M. & Bell, R.M. (1992) Inhibition of sphingosine kinase in vitro and in platelets. J. Biol. Chem. 267, 3154-3159.
19. Van Veldhoven, P.P. & Mannaerts, G.P. (1994) Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: Evidence for the existence of a sphingosine phosphatase. Biochem. J. 299, 597-601.
20. Ross, R. (1993) The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature (London) 362, 801-809.
21. Gasic, G.J., Gasic, T.B. & Stewart, C.C. (1968) Antimetastatic effects associated with platelet reduction. Proc. Natl. Acad. Sci. U.S.A. 61, 46-52.
22. Okoshi, H., Hakomori, S., Nisar, M., Zhou, Q., Kimura, S., Tashiro, K. & Igarashi, Y. (1991) Cell membrane signaling as target in cancer therapy II: Inhibitory effect of N,N,N-trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell-dependent platelet aggregation. Cancer Res. 51, 6019-6024.
23. Zahavi, J. & Kakkar, V.V. (1980) β-Thromboglobulin-a specific marker of in vivo platelet release reaction. Thromb. Haemostas. 44, 23-29.
24. Kaplan, K.L. & Owen, J. (1981) Plasma levels of β-thromboglobulin and platelet factor 4 as indices of platelet activation in vivo. Blood 57, 199-202.
25. Park, Y.S., Ruan, F., Hakomori, S. & Igarashi, Y. (1995) Cooperative inhibitory effect of N,N,N-trimethylsphingosine and sphingosine-1-phosphate, co-incorporated in liposomes, on B16 melanoma cell metastasis: Cell membrane signaling as a target in cancer therapy IV. Int. J. Oncol. 7, 487-494.
26. Krown, A.K., Page, M.T., Nguyen, C., Zechner, D., Gutierrez, V., Comstock, K.L., Glembotski, C., Quintana, J.E. & Sabbadini, R.A. (1996). Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. J. Clin. Invest. 98, 2854-2865.
27. Stack, G. & Snyder, E.L. (1994) Cytokine generation in stored platelet concentrates. Transfusion 34, 20-25.
28. Mangano, M.M., Chambers, L.A. & Kruskall, M.S. (1991) Limited efficacy of leukopoor platelets for prevention of febrile transfusion reactions. Am. J. Clin. Pathol. 95, 733-738.
29. Yatomi, Y., Ruan, F., Megidish, T., Toyokuni, T., Hakomori, S. & Igarashi, Y. (1996) N,N-D-imethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets. Biochemistry 35, 626-633.