메뉴 건너뛰기




Volumn 20, Issue 3, 2015, Pages 377-387

Somatostatin, neuronal vulnerability and behavioral emotionality

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; CORTISTATIN; GLUTAMATE DECARBOXYLASE 67; INITIATION FACTOR 2; SOMATOSTATIN; TRANSCRIPTOME; 7-METHYL-5-(1-((3-(TRIFLUOROMETHYL)PHENYL)ACETYL)-2,3-DIHYDRO-1H-INDOL-5-YL)-7H-PYRROLO(2,3-D)PYRIMIDIN-4-AMINE; ADENINE; ANTIDEPRESSANT AGENT; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; GREEN FLUORESCENT PROTEIN; INDOLE DERIVATIVE;

EID: 84924748164     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2014.184     Document Type: Article
Times cited : (136)

References (85)
  • 1
    • 0141567810 scopus 로고    scopus 로고
    • The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women
    • Kendler KS, Prescott CA, Myers J, Neale MC. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 2003; 60: 929-937
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 929-937
    • Kendler, K.S.1    Prescott, C.A.2    Myers, J.3    Neale, M.C.4
  • 3
    • 84876670027 scopus 로고    scopus 로고
    • The neuroprogressive nature of major depressive disorder: Pathways to disease evolution and resistance, and therapeutic implications
    • Moylan S, Maes M, Wray NR, Berk M. The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications. Mol Psychiatry 2012; 18: 595-606
    • (2012) Mol Psychiatry , vol.18 , pp. 595-606
    • Moylan, S.1    Maes, M.2    Wray, N.R.3    Berk, M.4
  • 4
    • 33751338530 scopus 로고    scopus 로고
    • Acute and longer-Term outcomes in depressed outpatients requiring one or several treatment steps: A
    • STAR D report
    • Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, et al. Acute and longer-Term outcomes in depressed outpatients requiring one or several treatment steps: a STAR.D report. Am J Psychiatry 2006; 163: 1905-1917
    • (2006) Am J Psychiatry , vol.163 , pp. 1905-1917
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Stewart, J.W.5    Warden, D.6
  • 5
    • 84885350213 scopus 로고    scopus 로고
    • Reduced brain somatostatin in mood disorders: A common pathophysiological substrate and drug target?
    • Lin LC, Sibille E. Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target? Front Pharmacol 2013; 4: 110
    • (2013) Front Pharmacol , vol.4 , pp. 110
    • Lin, L.C.1    Sibille, E.2
  • 6
    • 84874443445 scopus 로고    scopus 로고
    • Somatostatinergic systems: An update on brain functions in normal and pathological aging
    • Martel G, Dutar P, Epelbaum J, Viollet C. Somatostatinergic systems: an update on brain functions in normal and pathological aging. Front Endocrinol (Lausanne) 2012; 3: 154
    • (2012) Front Endocrinol (Lausanne , vol.3 , pp. 154
    • Martel, G.1    Dutar, P.2    Epelbaum, J.3    Viollet, C.4
  • 7
    • 84868599247 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder
    • Tripp A, Oh H, Guilloux JP, Martinowich K, Lewis DA, Sibille E. Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. Am J Psychiatry 2012; 169: 1194-1202
    • (2012) Am J Psychiatry , vol.169 , pp. 1194-1202
    • Tripp, A.1    Oh, H.2    Guilloux, J.P.3    Martinowich, K.4    Lewis, D.A.5    Sibille, E.6
  • 8
    • 79958864636 scopus 로고    scopus 로고
    • Gaba-related transcripts in the dorsolateral prefrontal cortex in mood disorders
    • Sibille E, Morris HM, Kota RS, Lewis DA. GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders. Int J Neuropsychopharmacol 2011; 14: 721-734
    • (2011) Int J Neuropsychopharmacol , vol.14 , pp. 721-734
    • Sibille, E.1    Morris, H.M.2    Kota, R.S.3    Lewis, D.A.4
  • 9
    • 84867898404 scopus 로고    scopus 로고
    • Molecular evidence for bdnf- and gaba-related dysfunctions in the amygdala of female subjects with major depression
    • Guilloux JP, Douillard-Guilloux G, Kota R, Wang X, Gardier AM, Martinowich K, et al. Molecular evidence for BDNF- And GABA-related dysfunctions in the amygdala of female subjects with major depression. Mol Psychiatry 2012; 17: 1130-1142
    • (2012) Mol Psychiatry , vol.17 , pp. 1130-1142
    • Guilloux, J.P.1    Douillard-Guilloux, G.2    Kota, R.3    Wang, X.4    Gardier, A.M.5    Martinowich, K.6
  • 10
    • 79751538430 scopus 로고    scopus 로고
    • Reduced somatostatin in subgenual anterior cingulate cortex in major depression
    • Tripp A, Kota RS, Lewis DA, Sibille E. Reduced somatostatin in subgenual anterior cingulate cortex in major depression. Neurobiol Dis 2011; 42: 116-124
    • (2011) Neurobiol Dis , vol.42 , pp. 116-124
    • Tripp, A.1    Kota, R.S.2    Lewis, D.A.3    Sibille, E.4
  • 11
    • 0021137464 scopus 로고
    • Morphology, distribution, and synaptic relations of somatostatin- and neuropeptide y-immunoreactive neurons in rat and monkey neocortex
    • Hendry SH, Jones EG, Emson PC. Morphology, distribution, and synaptic relations of somatostatin- And neuropeptide Y-immunoreactive neurons in rat and monkey neocortex. J Neurosci 1984; 4: 2497-2517
    • (1984) J Neurosci , vol.4 , pp. 2497-2517
    • Hendry, S.H.1    Jones, E.G.2    Emson, P.C.3
  • 12
    • 42949122457 scopus 로고    scopus 로고
    • Dendritic-Targeting gaba neurons in monkey prefrontal cortex: Comparison of somatostatin- and calretinin-immunoreactive axon terminals
    • Melchitzky DS, Lewis DA. Dendritic-Targeting GABA neurons in monkey prefrontal cortex: comparison of somatostatin- And calretinin-immunoreactive axon terminals. Synapse 2008; 62: 456-465
    • (2008) Synapse , vol.62 , pp. 456-465
    • Melchitzky, D.S.1    Lewis, D.A.2
  • 13
    • 77649268157 scopus 로고    scopus 로고
    • Immunochemical characterization of inhibitory mouse cortical neurons: Three chemically distinct classes of inhibitory cells
    • Xu X, Roby KD, Callaway EM. Immunochemical characterization of inhibitory mouse cortical neurons: three chemically distinct classes of inhibitory cells. J Comp Neurol 2010; 518: 389-404
    • (2010) J Comp Neurol , vol.518 , pp. 389-404
    • Xu, X.1    Roby, K.D.2    Callaway, E.M.3
  • 14
    • 84859217484 scopus 로고    scopus 로고
    • Unique functional properties of somatostatin-expressing gabaergic neurons in mouse barrel cortex
    • Gentet LJ, Kremer Y, Taniguchi H, Huang ZJ, Staiger JF, Petersen CC. Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex. Nat Neurosci 2012; 15: 607-612
    • (2012) Nat Neurosci , vol.15 , pp. 607-612
    • Gentet, L.J.1    Kremer, Y.2    Taniguchi, H.3    Huang, Z.J.4    Staiger, J.F.5    Petersen, C.C.6
  • 15
    • 84873307579 scopus 로고    scopus 로고
    • Gabaergic interneurons shape the functional maturation of the cortex
    • Le Magueresse C, Monyer H. GABAergic interneurons shape the functional maturation of the cortex. Neuron 2013; 77: 388-405
    • (2013) Neuron , vol.77 , pp. 388-405
    • Le Magueresse, C.1    Monyer, H.2
  • 18
    • 0021215764 scopus 로고
    • Low levels of somatostatin in human csf mark depressive episodes
    • Agren H, Lundqvist G. Low levels of somatostatin in human CSF mark depressive episodes. Psychoneuroendocrinology 1984; 9: 233-248
    • (1984) Psychoneuroendocrinology , vol.9 , pp. 233-248
    • Agren, H.1    Lundqvist, G.2
  • 20
    • 0027470020 scopus 로고
    • Cerebrospinal fluid immunoreactive somatostatin concentrations in patients with cushing's disease and major depression: Relationship to indices of corticotropinreleasing hormone and cortisol secretion
    • Kling MA, Rubinow DR, Doran AR, Roy A, Davis CL, Calabrese JR, et al. Cerebrospinal fluid immunoreactive somatostatin concentrations in patients with Cushing's disease and major depression: relationship to indices of corticotropinreleasing hormone and cortisol secretion. Neuroendocrinology 1993; 57: 79-88
    • (1993) Neuroendocrinology , vol.57 , pp. 79-88
    • Kling, M.A.1    Rubinow, D.R.2    Doran, A.R.3    Roy, A.4    Davis, C.L.5    Calabrese, J.R.6
  • 21
    • 0027375983 scopus 로고
    • Csf somatostatin in alzheimer's disease and major depression: Relationship to hypothalamic-pituitary-Adrenal axis and clinical measures
    • Molchan SE, Hill JL, Martinez RA, Lawlor BA, Mellow AM, Rubinow DR, et al. CSF somatostatin in Alzheimer's disease and major depression: relationship to hypothalamic-pituitary-Adrenal axis and clinical measures. Psychoneuroendocrinology 1993; 18: 509-519
    • (1993) Psychoneuroendocrinology , vol.18 , pp. 509-519
    • Molchan, S.E.1    Hill, J.L.2    Martinez, R.A.3    Lawlor, B.A.4    Mellow, A.M.5    Rubinow, D.R.6
  • 22
    • 23644431529 scopus 로고    scopus 로고
    • The stress system in the human brain in depression and neurodegeneration
    • Swaab DF, Bao AM, Lucassen PJ. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 2005; 4: 141-194
    • (2005) Ageing Res Rev , vol.4 , pp. 141-194
    • Swaab, D.F.1    Bao, A.M.2    Lucassen, P.J.3
  • 23
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000; 23: 477-501
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 24
    • 38049081662 scopus 로고    scopus 로고
    • Major depressive disorder
    • Belmaker RH, Agam G. Major depressive disorder. N Engl J Med 2008; 358: 55-68
    • (2008) N Engl J Med , vol.358 , pp. 55-68
    • Belmaker, R.H.1    Agam, G.2
  • 25
    • 84873958606 scopus 로고    scopus 로고
    • Central actions of somatostatin-28 and oligosomatostatin agonists to prevent components of the endocrine, autonomic and visceral responses to stress through interaction with different somatostatin receptor subtypes
    • Stengel A, Rivier J, Tache Y. Central actions of somatostatin-28 and oligosomatostatin agonists to prevent components of the endocrine, autonomic and visceral responses to stress through interaction with different somatostatin receptor subtypes. Curr Pharm Des 2013; 19: 98-105
    • (2013) Curr Pharm des , vol.19 , pp. 98-105
    • Stengel, A.1    Rivier, J.2    Tache, Y.3
  • 26
    • 0018833223 scopus 로고
    • Somatostatin analog: Plasma catecholamine suppression mediated by the central nervous system
    • Fisher DA, Brown MR. Somatostatin analog: plasma catecholamine suppression mediated by the central nervous system. Endocrinology 1980; 107: 714-718
    • (1980) Endocrinology , vol.107 , pp. 714-718
    • Fisher, D.A.1    Brown, M.R.2
  • 27
    • 0021341532 scopus 로고
    • Central nervous system regulation of adrenocorticotropin secretion: Role of somatostatins
    • Brown MR, Rivier C, Vale W. Central nervous system regulation of adrenocorticotropin secretion: role of somatostatins. Endocrinology 1984; 114: 1546-1549
    • (1984) Endocrinology , vol.114 , pp. 1546-1549
    • Brown, M.R.1    Rivier, C.2    Vale, W.3
  • 28
    • 79959324854 scopus 로고    scopus 로고
    • Central administration of pan-somatostatin agonist odt8-sst prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats
    • Stengel A, Goebel-Stengel M, Wang L, Luckey A, Hu E, Rivier J, et al. Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats. Neurogastroenterol Motil 2011; 23: e294-e308
    • (2011) Neurogastroenterol Motil , vol.23 , pp. e294-e308
    • Stengel, A.1    Goebel-Stengel, M.2    Wang, L.3    Luckey, A.4    Hu, E.5    Rivier, J.6
  • 29
    • 35748938777 scopus 로고    scopus 로고
    • Association of different adverse life events with distinct patterns of depressive symptoms
    • quiz 1622
    • Keller MC, Neale MC, Kendler KS. Association of different adverse life events with distinct patterns of depressive symptoms. Am J Psychiatry 2007; 164: 1521-1529, quiz 1622
    • (2007) Am J Psychiatry , vol.164 , pp. 1521-1529
    • Keller, M.C.1    Neale, M.C.2    Kendler, K.S.3
  • 30
    • 0032726641 scopus 로고    scopus 로고
    • Brain somatostatin: A candidate inhibitory role in seizures and epileptogenesis
    • Vezzani A, Hoyer D. Brain somatostatin: a candidate inhibitory role in seizures and epileptogenesis. Eur J Neurosci 1999; 11: 3767-3776
    • (1999) Eur J Neurosci , vol.11 , pp. 3767-3776
    • Vezzani, A.1    Hoyer, D.2
  • 31
    • 77951097223 scopus 로고    scopus 로고
    • Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder
    • Ponomarev I, Rau V, Eger EI, Harris RA, Fanselow MS. Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder. Neuropsychopharmacology 2010; 35: 1402-1411
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1402-1411
    • Ponomarev, I.1    Rau, V.2    Eger, E.I.3    Harris, R.A.4    Fanselow, M.S.5
  • 32
    • 79952325340 scopus 로고    scopus 로고
    • Activitydependent brain-derived neurotrophic factor expression regulates cortistatininterneurons and sleep behavior
    • Martinowich K, Schloesser RJ, Jimenez DV, Weinberger DR, Lu B. Activitydependent brain-derived neurotrophic factor expression regulates cortistatininterneurons and sleep behavior. Mol Brain 2011; 4: 11
    • (2011) Mol Brain , vol.4 , pp. 11
    • Martinowich, K.1    Schloesser, R.J.2    Jimenez, D.V.3    Weinberger, D.R.4    Lu, B.5
  • 33
    • 33745632036 scopus 로고    scopus 로고
    • Specificity and timing of neocortical transcriptome changes in response to bdnf gene ablation during embryogenesis or adulthood
    • Glorioso C, Sabatini M, Unger T, Hashimoto T, Monteggia LM, Lewis DA, et al. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol Psychiatry 2006; 11: 633-648
    • (2006) Mol Psychiatry , vol.11 , pp. 633-648
    • Glorioso, C.1    Sabatini, M.2    Unger, T.3    Hashimoto, T.4    Monteggia, L.M.5    Lewis, D.A.6
  • 34
    • 23644450220 scopus 로고    scopus 로고
    • Area-specific effects of brain-derived neurotrophic factor (bdnf) genetic ablation on various neuronal subtypes of the mouse brain
    • Grosse G, Djalali S, Deng DR, Holtje M, Hinz B, Schwartzkopff K, et al. Area-specific effects of brain-derived neurotrophic factor (BDNF) genetic ablation on various neuronal subtypes of the mouse brain. Brain Res Dev Brain Res 2005; 156: 111-126
    • (2005) Brain Res Dev Brain Res , vol.156 , pp. 111-126
    • Grosse, G.1    Djalali, S.2    Deng, D.R.3    Holtje, M.4    Hinz, B.5    Schwartzkopff, K.6
  • 37
    • 79961168730 scopus 로고    scopus 로고
    • Anxiolytic-like effects of somatostatin isoforms sst 14 and sst 28 in two animal models (rattus norvegicus) after intra-Amygdalar and intra-septal microinfusions
    • Yeung M, Engin E, Treit D. Anxiolytic-like effects of somatostatin isoforms SST 14 and SST 28 in two animal models (Rattus norvegicus) after intra-Amygdalar and intra-septal microinfusions. Psychopharmacology (Berl) 2011; 216: 557-567
    • (2011) Psychopharmacology (Berl , vol.216 , pp. 557-567
    • Yeung, M.1    Engin, E.2    Treit, D.3
  • 38
    • 84855775642 scopus 로고    scopus 로고
    • The anxiolytic effects of somatostatin following intra-septal and intra-Amygdalar microinfusions are reversed by the selective sst2 antagonist prl2903
    • Yeung M, Treit D. The anxiolytic effects of somatostatin following intra-septal and intra-Amygdalar microinfusions are reversed by the selective sst2 antagonist PRL2903. Pharmacol Biochem Behav 2012; 101: 88-92
    • (2012) Pharmacol Biochem Behav , vol.101 , pp. 88-92
    • Yeung, M.1    Treit, D.2
  • 39
    • 84904463587 scopus 로고    scopus 로고
    • Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice
    • Soumier A, Sibille E. Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice. Neuropsychopharmacology 2014; 39: 2252-2262
    • (2014) Neuropsychopharmacology , vol.39 , pp. 2252-2262
    • Soumier, A.1    Sibille, E.2
  • 40
    • 80053128156 scopus 로고    scopus 로고
    • A resource of cre driver lines for genetic targeting of gabaergic neurons in cerebral cortex
    • Taniguchi H, He M, Wu P, Kim S, Paik R, Sugino K, et al. A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron 2011; 71: 995-1013
    • (2011) Neuron , vol.71 , pp. 995-1013
    • Taniguchi, H.1    He, M.2    Wu, P.3    Kim, S.4    Paik, R.5    Sugino, K.6
  • 41
    • 64949179797 scopus 로고    scopus 로고
    • Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal
    • Surget A, Wang Y, Leman S, Ibarguen-Vargas Y, Edgar N, Griebel G, et al. Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal. Neuropsychopharmacology 2009; 34: 1363-1380
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1363-1380
    • Surget, A.1    Wang, Y.2    Leman, S.3    Ibarguen-Vargas, Y.4    Edgar, N.5    Griebel, G.6
  • 42
    • 0034655423 scopus 로고    scopus 로고
    • Genetic inactivation of the serotonin(1a) receptor in mice results in downregulation of major gaba(a) receptor alpha subunits, reduction of gaba(a) receptor binding, and benzodiazepine-resistant anxiety
    • Sibille E, Pavlides C, Benke D, Toth M. Genetic inactivation of the serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety. J Neurosci 2000; 20: 2758-2765
    • (2000) J Neurosci , vol.20 , pp. 2758-2765
    • Sibille, E.1    Pavlides, C.2    Benke, D.3    Toth, M.4
  • 43
    • 79953055982 scopus 로고    scopus 로고
    • Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex
    • Guilloux JP, Seney M, Edgar N, Sibille E. Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex. J Neurosci Methods 2011; 197: 21-31
    • (2011) J Neurosci Methods , vol.197 , pp. 21-31
    • Guilloux, J.P.1    Seney, M.2    Edgar, N.3    Sibille, E.4
  • 44
    • 65649125633 scopus 로고    scopus 로고
    • Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
    • David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009; 62: 479-493
    • (2009) Neuron , vol.62 , pp. 479-493
    • David, D.J.1    Samuels, B.A.2    Rainer, Q.3    Wang, J.W.4    Marsteller, D.5    Mendez, I.6
  • 45
    • 79955498437 scopus 로고    scopus 로고
    • A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism
    • Lin LC, Lewis DA, Sibille E. A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism. Mol Brain 2011; 4: 18
    • (2011) Mol Brain , vol.4 , pp. 18
    • Lin, L.C.1    Lewis, D.A.2    Sibille, E.3
  • 46
    • 84883453343 scopus 로고    scopus 로고
    • Suppression of eif2alpha kinases alleviates alzheimer's disease-related plasticity and memory deficits
    • Ma T, Trinh MA, Wexler AJ, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2alpha kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci 2013; 16: 1299-1305
    • (2013) Nat Neurosci , vol.16 , pp. 1299-1305
    • Ma, T.1    Trinh, M.A.2    Wexler, A.J.3    Bourbon, C.4    Gatti, E.5    Pierre, P.6
  • 47
    • 84885463900 scopus 로고    scopus 로고
    • Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice
    • 206ra138
    • Moreno JA, Halliday M, Molloy C, Radford H, Verity N, Axten JM, et al. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Sci Transl Med 2013; 5: 206ra138
    • (2013) Sci Transl Med , vol.5
    • Moreno, J.A.1    Halliday, M.2    Molloy, C.3    Radford, H.4    Verity, N.5    Axten, J.M.6
  • 48
    • 84895822652 scopus 로고    scopus 로고
    • Therapeutic modulation of eif2alpha phosphorylation rescues tdp-43 toxicity in amyotrophic lateral sclerosis disease models
    • Kim HJ, Raphael AR, Ladow ES, McGurk L, Weber RA, Trojanowski JQ, et al. Therapeutic modulation of eIF2alpha phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Nat Genet 2014; 46: 152-160
    • (2014) Nat Genet , vol.46 , pp. 152-160
    • Kim, H.J.1    Raphael, A.R.2    Ladow, E.S.3    McGurk, L.4    Weber, R.A.5    Trojanowski, J.Q.6
  • 49
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-htt gene
    • Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301: 386-389
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3    Taylor, A.4    Craig, I.W.5    Harrington, H.6
  • 51
    • 84883201199 scopus 로고    scopus 로고
    • Models of depression: Unpredictable chronic mild stress in mice
    • Chapter 5, Unit 5
    • Nollet M, Le Guisquet AM, Belzung C. Models of depression: unpredictable chronic mild stress in mice. Curr Protoc Pharmacol 2013 (Chapter 5, Unit 5): 65
    • (2013) Curr Protoc Pharmacol , pp. 65
    • Nollet, M.1    Le Guisquet, A.M.2    Belzung, C.3
  • 52
    • 0031877371 scopus 로고    scopus 로고
    • Somatostatin administration modifies food intake, body weight, and gut motility in rat
    • Scalera G, Tarozzi G. Somatostatin administration modifies food intake, body weight, and gut motility in rat. Peptides 1998; 19: 991-997
    • (1998) Peptides , vol.19 , pp. 991-997
    • Scalera, G.1    Tarozzi, G.2
  • 53
    • 0024412917 scopus 로고
    • Somatostatin inhibits the effect of secretin on bile flow and on hepatic bilirubin transport in the rat
    • Ricci GL, Fevery J. Somatostatin inhibits the effect of secretin on bile flow and on hepatic bilirubin transport in the rat. Gut 1989; 30: 1266-1269
    • (1989) Gut , vol.30 , pp. 1266-1269
    • Ricci, G.L.1    Fevery, J.2
  • 56
    • 43549085498 scopus 로고    scopus 로고
    • Cortistatin-functions in the central nervous system
    • de Lecea L. Cortistatin-functions in the central nervous system. Mol Cell Endocrinol 2008; 286: 88-95
    • (2008) Mol Cell Endocrinol , vol.286 , pp. 88-95
    • De Lecea, L.1
  • 57
    • 37149031347 scopus 로고    scopus 로고
    • Increased er stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis
    • Nagata T, Ilieva H, Murakami T, Shiote M, Narai H, Ohta Y, et al. Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis. Neurol Res 2007; 29: 767-771
    • (2007) Neurol Res , vol.29 , pp. 767-771
    • Nagata, T.1    Ilieva, H.2    Murakami, T.3    Shiote, M.4    Narai, H.5    Ohta, Y.6
  • 58
    • 84894571860 scopus 로고    scopus 로고
    • Causal analysis approaches in ingenuity pathway analysis
    • Kramer A, Green J, Pollard J Jr, Tugendreich S. Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics 2014; 30: 523-530
    • (2014) Bioinformatics , vol.30 , pp. 523-530
    • Kramer, A.1    Green, J.2    Pollard, J.3    Tugendreich, S.4
  • 59
    • 33744477075 scopus 로고    scopus 로고
    • Anxiogenic-like effect of chronic corticosterone in the lightdark emergence task in mice
    • Ardayfio P, Kim KS. Anxiogenic-like effect of chronic corticosterone in the lightdark emergence task in mice. Behav Neurosci 2006; 120: 249-256
    • (2006) Behav Neurosci , vol.120 , pp. 249-256
    • Ardayfio, P.1    Kim, K.S.2
  • 60
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000; 6: 1099-1108
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6
  • 61
    • 84861450392 scopus 로고    scopus 로고
    • Sustained translational repression by eif2alpha-p mediates prion neurodegeneration
    • Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, et al. Sustained translational repression by eIF2alpha-P mediates prion neurodegeneration. Nature 2012; 485: 507-511
    • (2012) Nature , vol.485 , pp. 507-511
    • Moreno, J.A.1    Radford, H.2    Peretti, D.3    Steinert, J.R.4    Verity, N.5    Martin, M.G.6
  • 62
    • 13644256191 scopus 로고    scopus 로고
    • A selective inhibitor of eif2alpha dephosphorylation protects cells from er stress
    • Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, et al. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005; 307: 935-939
    • (2005) Science , vol.307 , pp. 935-939
    • Boyce, M.1    Bryant, K.F.2    Jousse, C.3    Long, K.4    Harding, H.P.5    Scheuner, D.6
  • 63
    • 84866905708 scopus 로고    scopus 로고
    • Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1h-indol-5-yl)-7h-pyrrolo[ 2,3-d]pyrimidin-4-Amine (gsk2606414), a potent and selective first-in-class inhibitor of protein kinase r (pkr)-like endoplasmic reticulum kinase (perk
    • Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW, et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[ 2,3-d]pyrimidin-4-Amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem 2012; 55: 7193-7207
    • (2012) J Med Chem , vol.55 , pp. 7193-7207
    • Axten, J.M.1    Medina, J.R.2    Feng, Y.3    Shu, A.4    Romeril, S.P.5    Grant, S.W.6
  • 64
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003; 301: 805-809
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1    Saxe, M.2    Gross, C.3    Surget, A.4    Battaglia, F.5    Dulawa, S.6
  • 66
    • 0015595922 scopus 로고
    • Primary structure of somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone
    • Burgus R, Ling N, Butcher M, Guillemin R. Primary structure of somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone. Proc Natl Acad Sci USA 1973; 70: 684-688
    • (1973) Proc Natl Acad Sci USA , vol.70 , pp. 684-688
    • Burgus, R.1    Ling, N.2    Butcher, M.3    Guillemin, R.4
  • 67
    • 46349088792 scopus 로고    scopus 로고
    • Everything has rhythm: Focus on glucocorticoid pulsatility
    • de Kloet ER, Sarabdjitsingh RA. Everything has rhythm: focus on glucocorticoid pulsatility. Endocrinology 2008; 149: 3241-3243
    • (2008) Endocrinology , vol.149 , pp. 3241-3243
    • De Kloet, E.R.1    Sarabdjitsingh, R.A.2
  • 68
    • 0142042993 scopus 로고    scopus 로고
    • Neurobiology of emotion perception ii: Implications for major psychiatric disorders
    • Phillips ML, Drevets WC, Rauch SL, Lane R. Neurobiology of emotion perception II: implications for major psychiatric disorders. Biol Psychiatry 2003; 54: 515-528
    • (2003) Biol Psychiatry , vol.54 , pp. 515-528
    • Phillips, M.L.1    Drevets, W.C.2    Rauch, S.L.3    Lane, R.4
  • 69
    • 0032944684 scopus 로고    scopus 로고
    • Reciprocal limbic-cortical function and negative mood: Converging pet findings in depression and normal sadness
    • Mayberg HS, Liotti M, Brannan SK, McGinnis S, Mahurin RK, Jerabek PA, et al. Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am J Psychiatry 1999; 156: 675-682
    • (1999) Am J Psychiatry , vol.156 , pp. 675-682
    • Mayberg, H.S.1    Liotti, M.2    Brannan, S.K.3    McGinnis, S.4    Mahurin, R.K.5    Jerabek, P.A.6
  • 71
    • 78651496992 scopus 로고    scopus 로고
    • Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice
    • Kim SS, Wang H, Li XY, Chen T, Mercaldo V, Descalzi G, et al. Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice. Mol Brain 2011; 4: 6
    • (2011) Mol Brain , vol.4 , pp. 6
    • Kim, S.S.1    Wang, H.2    Li, X.Y.3    Chen, T.4    Mercaldo, V.5    Descalzi, G.6
  • 73
    • 33646701365 scopus 로고    scopus 로고
    • Compensatory changes in the hippocampus of somatostatin knockout mice: Upregulation of somatostatin receptor 2 and its function in the control of bursting activity and synaptic transmission
    • Cammalleri M, Cervia D, Dal Monte M, Martini D, Langenegger D, Fehlmann D, et al. Compensatory changes in the hippocampus of somatostatin knockout mice: upregulation of somatostatin receptor 2 and its function in the control of bursting activity and synaptic transmission. Eur J Neurosci 2006; 23: 2404-2422
    • (2006) Eur J Neurosci , vol.23 , pp. 2404-2422
    • Cammalleri, M.1    Cervia, D.2    Dal Monte, M.3    Martini, D.4    Langenegger, D.5    Fehlmann, D.6
  • 74
    • 4344700859 scopus 로고    scopus 로고
    • Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress
    • Pothion S, Bizot JC, Trovero F, Belzung C. Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress. Behav Brain Res 2004; 155: 135-146
    • (2004) Behav Brain Res , vol.155 , pp. 135-146
    • Pothion, S.1    Bizot, J.C.2    Trovero, F.3    Belzung, C.4
  • 75
    • 0023636527 scopus 로고
    • Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
    • Willner P, Towell A, Sampson D, Sophokleous S, Muscat R. Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berl) 1987; 93: 358-364
    • (1987) Psychopharmacology (Berl , vol.93 , pp. 358-364
    • Willner, P.1    Towell, A.2    Sampson, D.3    Sophokleous, S.4    Muscat, R.5
  • 76
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8: 519-529
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 77
    • 84899844505 scopus 로고    scopus 로고
    • Control of dopaminergic neuron survival by the unfolded protein response transcription factor xbp1
    • Valdes P, Mercado G, Vidal RL, Molina C, Parsons G, Court FA, et al. Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1. Proc Natl Acad Sci USA 2014; 111: 6804-6809
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 6804-6809
    • Valdes, P.1    Mercado, G.2    Vidal, R.L.3    Molina, C.4    Parsons, G.5    Court, F.A.6
  • 78
    • 84897002606 scopus 로고    scopus 로고
    • Er stressinduced eif2-Alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin
    • Leitman J, Barak B, Benyair R, Shenkman M, Ashery U, Hartl FU, et al. ER stressinduced eIF2-Alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin. PLoS One 2014; 9: e90803
    • (2014) PLoS One , vol.9 , pp. e90803
    • Leitman, J.1    Barak, B.2    Benyair, R.3    Shenkman, M.4    Ashery, U.5    Hartl, F.U.6
  • 79
    • 67349164383 scopus 로고    scopus 로고
    • A role for motoneuron subtype-selective er stress in disease manifestations of fals mice
    • Saxena S, Cabuy E, Caroni P. A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice. Nat Neurosci 2009; 12: 627-636
    • (2009) Nat Neurosci , vol.12 , pp. 627-636
    • Saxena, S.1    Cabuy, E.2    Caroni, P.3
  • 80
    • 84897094564 scopus 로고    scopus 로고
    • Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
    • Hetz C, Mollereau B. Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat Rev Neurosci 2014; 15: 233-249
    • (2014) Nat Rev Neurosci , vol.15 , pp. 233-249
    • Hetz, C.1    Mollereau, B.2
  • 81
    • 0037011917 scopus 로고    scopus 로고
    • Ire1 couples endoplasmic reticulum load to secretory capacity by processing the xbp-1 mrna
    • Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, et al. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002; 415: 92-96
    • (2002) Nature , vol.415 , pp. 92-96
    • Calfon, M.1    Zeng, H.2    Urano, F.3    Till, J.H.4    Hubbard, S.R.5    Harding, H.P.6
  • 82
    • 0141730405 scopus 로고    scopus 로고
    • Impaired feedback regulation of xbp1 as a genetic risk factor for bipolar disorder
    • Kakiuchi C, Iwamoto K, Ishiwata M, Bundo M, Kasahara T, Kusumi I, et al. Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder. Nat Genet 2003; 35: 171-175
    • (2003) Nat Genet , vol.35 , pp. 171-175
    • Kakiuchi, C.1    Iwamoto, K.2    Ishiwata, M.3    Bundo, M.4    Kasahara, T.5    Kusumi, I.6
  • 83
    • 53449098260 scopus 로고    scopus 로고
    • Attenuated bdnf-induced upregulation of gabaergic markers in neurons lacking xbp1
    • Hayashi A, Kasahara T, Kametani M, Kato T. Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1. Biochem Biophys Res Commun 2008; 376: 758-763
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 758-763
    • Hayashi, A.1    Kasahara, T.2    Kametani, M.3    Kato, T.4
  • 84
    • 83255171042 scopus 로고    scopus 로고
    • Suppression of pkr promotes network excitability and enhanced cognition by interferongamma-mediated disinhibition
    • Zhu PJ, Huang W, Kalikulov D, Yoo JW, Placzek AN, Stoica L, et al. Suppression of PKR promotes network excitability and enhanced cognition by interferongamma-mediated disinhibition. Cell 2011; 147: 1384-1396
    • (2011) Cell , vol.147 , pp. 1384-1396
    • Zhu, P.J.1    Huang, W.2    Kalikulov, D.3    Yoo, J.W.4    Placzek, A.N.5    Stoica, L.6
  • 85
    • 84863086454 scopus 로고    scopus 로고
    • Brain-specific disruption of the eif2alpha kinase perk decreases atf4 expression and impairs behavioral flexibility
    • Trinh MA, Kaphzan H, Wek RC, Pierre P, Cavener DR, Klann E. Brain-specific disruption of the eIF2alpha kinase PERK decreases ATF4 expression and impairs behavioral flexibility. Cell Rep 2012; 1: 676-688
    • (2012) Cell Rep , vol.1 , pp. 676-688
    • Trinh, M.A.1    Kaphzan, H.2    Wek, R.C.3    Pierre, P.4    Cavener, D.R.5    Klann, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.