Reduced somatostatin in subgenual anterior cingulate cortex in major depression

Neurobiology of Disease

Volumn 42, Issue 1, 2011, Pages 116-124

  Tripp, Adam ^a   Kota, Rama S ^a   Lewis, David A ^a,b   Sibille, Etienne ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Age; Cingulate; Female; GABA; Interneuron; Major depression; Male; Postmortem; Somatostatin

Indexed keywords

MESSENGER RNA; SOMATOSTATIN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ANTERIOR CINGULATE; ARTICLE; AUTOPSY; BRAIN LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; SUBGENUAL ANTERIOR CINGULATE CORTEX; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; COHORT STUDIES; DEPRESSIVE DISORDER, MAJOR; DOWN-REGULATION; FEMALE; GYRUS CINGULI; HUMANS; MALE; MIDDLE AGED; NEURAL PATHWAYS; PROTEIN PRECURSORS; SOMATOSTATIN; YOUNG ADULT;

EID: 79751538430     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.01.014     Document Type: Article

References (57)

1. Agid Y., Buzsaki G., Diamond D.M., Frackowiak R., Giedd J., Girault J.A., et al. How can drug discovery for psychiatric disorders be improved?. Nat. Rev. Drug Discov. 2007, 6:189-201.
2. Baraban S.C., Tallent M.K. Interneuron diversity series: interneuronal neuropeptides - endogenous regulators of neuronal excitability. Trends Neurosci. 2004, 27:135-142.
3. Beasley C.L., Zhang Z.J., Patten I., Reynolds G.P. Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins. Biol. Psychiatry 2002, 52:708-715.
4. Cotter D., Landau S., Beasley C., Stevenson R., Chana G., MacMillan L., et al. The density and spatial distribution of GABAergic neurons, labelled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia. Biol. Psychiatry 2002, 51:377-386.
5. Erraji-Benchekroun L., Underwood M.D., Arango V., Galfalvy H., Pavlidis P., Smyrniotopoulos P., et al. Molecular aging in human prefrontal cortex is selective and continuous throughout adult life. Biol. Psychiatry 2005, 57:549-558.
6. Fiske A., Wetherell J.L., Gatz M. Depression in older adults. Annu. Rev. Clin. Psychol. 2009, 5:363-389.
7. Frieboes R.M., Murck H., Schier T., Holsboer F., Steiger A. Somatostatin impairs sleep in elderly human subjects. Neuropsychopharmacology 1997, 16:339-345.
8. Fung S.J., Webster M.J., Sivagnanasundaram S., Duncan C., Elashoff M., Weickert C.S. Expression of Interneuron Markers in the Dorsolateral Prefrontal Cortex of the Developing Human and in Schizophrenia. Am. J. Psychiatry 2010, 167(12):1479-1488.
9. George M.S., Nahas Z., Kozel F.A., Goldman J., Molloy M., Oliver N. Improvement of depression following transcranial magnetic stimulation. Curr. Psychiatry Rep. 1999, 1:114-124.
10. Glantz L.A., Austin M.C., Lewis D.A. Normal cellular levels of synaptophysin mRNA expression in the prefrontal cortex of subjects with schizophrenia. Biol. Psychiatry 2000, 48:389-397.
11. Glorioso C., Sabatini M., Unger T., Hashimoto T., Monteggia L.M., Lewis D.A., et al. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol. Psychiatry 2006, 11:633-648.
12. Glorioso C., Oh S., Douillard-Guilloux G., Sibille E. Brain Molecular Aging, Promotion of Neurological Disease and Modulation by Sirtuin5 Longevity Gene Polymorphism. Neurobiol Dis. 2011, 41(2):279-290.
13. Hashimoto T., Volk D.W., Eggan S.M., Mirnics K., Pierri J.N., Sun Z., et al. Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J. Neurosci. 2003, 23:6315-6326.
14. Hashimoto T., Bergen S.E., Nguyen Q.L., Xu B., Monteggia L.M., Pierri J.N., et al. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J. Neurosci. 2005, 25:372-383.
15. Hashimoto T., Bazmi H.H., Mirnics K., Wu Q., Sampson A.R., Lewis D.A. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am. J. Psychiatry 2008, 165:479-489.
16. Hayashi M., Yamashita A., Shimizu K. Somatostatin and brain-derived neurotrophic factor mRNA expression in the primate brain: decreased levels of mRNAs during aging. Brain Res. 1997, 749:283-289.
17. Hayes T.L., Cameron J.L., Fernstrom J.D., Lewis D.A. A comparative analysis of the distribution of prosomatostatin-derived peptides in human and monkey neocortex. J. Comp. Neurol. 1991, 303:584-599.
18. Hoffman G.E., Sladek J.R. Age-related changes in dopamine, LHRH and somatostatin in the rat hypothalamus. Neurobiol. Aging 1980, 1:27-37.
19. Imbeaud S., Graudens E., Boulanger V., Barlet X., Zaborski P., Eveno E., et al. Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Res. 2005, 33:e56.
20. Jin X., Hu H., Mathers P.H., Agmon A. Brain-derived neurotrophic factor mediates activity-dependent dendritic growth in nonpyramidal neocortical interneurons in developing organotypic cultures. J. Neurosci. 2003, 23:5662-5673.
21. Kessler R.C., Berglund P., Demler O., Jin R., Koretz D., Merikangas K.R., et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003, 289:3095-3105.
22. Kupfer D.J., Jarrett D.B., Ehlers C.L. The effect of SRIF on the EEG sleep of normal men. Psychoneuroendocrinology 1992, 17:37-43.
23. Levinson A.J., Fitzgerald P.B., Favalli G., Blumberger D.M., Daigle M., Daskalakis Z.J. Evidence of cortical inhibitory deficits in major depressive disorder. Biol. Psychiatry 2010, 67:458-464.
24. Lewis D.A., Gonzalez-Burgos G. Pathophysiologically based treatment interventions in schizophrenia. Nat. Med. 2006, 12:1016-1022.
25. Lewis D.A., Cruz D.A., Melchitzky D.S., Pierri J.N. Lamina-specific deficits in parvalbumin-immunoreactive varicosities in the prefrontal cortex of subjects with schizophrenia: evidence for fewer projections from the thalamus. Am. J. Psychiatry 2001, 158:1411-1422.
26. Maciag D., Hughes J., O'Dwyer G., Pride Y., Stockmeier C.A., Sanacora G., et al. Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies. Biol. Psychiatry 2010, 67:465-470.
27. Mayberg H.S. Modulating limbic-cortical circuits in depression: targets of antidepressant treatments. Semin. Clin. Neuropsychiatry 2002, 7:255-268.
28. Mayberg H.S., Liotti M., Brannan S.K., McGinnis S., Mahurin R.K., Jerabek P.A., et al. Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am. J. Psychiatry 1999, 156:675-682.
29. Mellios N., Huang H.S., Baker S.P., Galdzicka M., Ginns E., Akbarian S. Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia. Biol. Psychiatry 2009, 65(12):1006-1014.
30. Morris H.M., Hashimoto T., Lewis D.A. Alterations in somatostatin mRNA expression in the dorsolateral prefrontal cortex of subjects with schizophrenia or schizoaffective disorder. Cereb. Cortex 2008, 18:1575-1587.
31. Newton S.S., Collier E.F., Hunsberger J., Adams D., Terwilliger R., Selvanayagam E., et al. Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors. J. Neurosci. 2003, 23:10841-10851.
32. Nobler M.S., Oquendo M.A., Kegeles L.S., Malone K.M., Campbell C.C., Sackeim H.A., et al. Decreased regional brain metabolism after ect. Am. J. Psychiatry 2001, 158:305-308.
33. Pallis E., Vasilaki A., Fehlmann D., Kastellakis A., Hoyer D., Spyraki C., et al. Antidepressants influence somatostatin levels and receptor pharmacology in brain. Neuropsychopharmacology 2009, 34:952-963.
34. Pantazopoulos H., Lange N., Baldessarini R.J., Berretta S. Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia. Biol. Psychiatry 2007, 61:640-652.
35. Post R.M., Rubinow D.R., Kling M.A., Berrettini W., Gold P.W. Neuroactive substances in cerebrospinal fluid. Normal and pathological regulatory mechanisms. Ann. N. Y. Acad. Sci. 1988, 531:15-28.
36. Rage F., Riteau B., Alonso G., Tapia-Arancibia L. Brain-derived neurotrophic factor and neurotrophin-3 enhance somatostatin gene expression through a likely direct effect on hypothalamic somatostatin neurons. Endocrinology 1999, 140:909-916.
37. Rajkowska G., Miguel-Hidalgo J.J., Wei J., Dilley G., Pittman S.D., Meltzer H.Y., et al. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol. Psychiatry 1999, 45:1085-1098.
38. Rajkowska G., O'Dwyer G., Teleki Z., Stockmeier C.A., Miguel-Hidalgo J.J. GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depression. Neuropsychopharmacology 2007, 32:471-482.
39. Rubinow D.R., Davis C.L., Post R.M. Somatostatin in neuropsychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 1988, 12:S137-S155. (Suppl.).
40. Sakai T., Oshima A., Nozaki Y., Ida I., Haga C., Akiyama H., et al. Changes in density of calcium-binding-protein-immunoreactive GABAergic neurons in prefrontal cortex in schizophrenia and bipolar disorder. Neuropathology 2008, 28:143-150.
41. Sanacora G., Mason G.F., Rothman D.L., Behar K.L., Hyder F., Petroff O.A., et al. Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch. Gen. Psychiatry 1999, 56:1043-1047.
42. Sanacora G., Mason G.F., Rothman D.L., Krystal J.H. Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. Am. J. Psychiatry 2002, 159:663-665.
43. Sanacora G., Mason G.F., Rothman D.L., Hyder F., Ciarcia J.J., Ostroff R.B., et al. Increased cortical GABA concentrations in depressed patients receiving ECT. Am. J. Psychiatry 2003, 160:577-579.
44. Sanacora G., Gueorguieva R., Epperson C.N., Wu Y.T., Appel M., Rothman D.L., et al. Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Arch. Gen. Psychiatry 2004, 61:705-713.
45. Seminowicz D.A., Mayberg H.S., McIntosh A.R., Goldapple K., Kennedy S., Segal Z., et al. Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage 2004, 22:409-418.
46. Sharma R.P., Bissette G., Janicak P.G., Davis J.M., Nemeroff C.B. Elevation of CSF somatostatin concentrations in mania. Am. J. Psychiatry 1995, 152:1807-1809.
47. Sibille E., Wang Y., Joeyen-Waldorf J., Gaiteri C., Surget A., Oh S., et al. A molecular signature of depression in the amygdala. Am. J. Psychiatry 2009, 166:1011-1024.
48. Sibille E., Morris H.M., Kota R., Lewis D.A. GABA-related Transcripts in the Dorsolateral Prefrontal Cortex in Mood Disorders. Int J. Neuropsychopharmacol. 2011, Jan 13, 1-14. (Electronic publication ahead of print).
49. Spier A.D., de Lecea L. Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions. Brain Res. Brain Res. Rev. 2000, 33:228-241.
50. Spitzer R.L., Williams J.B., Gibbon M., First M.B. The structured clinical interview for DSM-III-R (SCID). I: History, rationale, and description. Arch. Gen. Psychiatry 1992, 49:624-629.
51. Surget A., Wang Y., Leman S., Ibarguen-Vargas Y., Edgar N., Griebel G., et al. Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal. Neuropsychopharmacology 2009, 34:1363-1380.
52. Talbot P.S., Cooper S.J. Anterior cingulate and subgenual prefrontal blood flow changes following tryptophan depletion in healthy males. Neuropsychopharmacology 2006, 31:1757-1767.
53. Valentine G.W., Sanacora G. Targeting glial physiology and glutamate cycling in the treatment of depression. Biochem. Pharmacol. 2009, 78:431-439.
54. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3. (RESEARCH0034).
55. Viollet C., Lepousez G., Loudes C., Videau C., Simon A., Epelbaum J. Somatostatinergic systems in brain: networks and functions. Mol. Cell. Endocrinol. 2008, 286:75-87.
56. Volk D.W., Austin M.C., Pierri J.N., Sampson A.R., Lewis D.A. Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch. Gen. Psychiatry 2000, 57:237-245.
57. Whitlock M.C. Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. J. Evol. Biol. 2005, 18:1368-1373.