Models of depression: Unpredictable chronic mild stress in mice

Current Protocols in Pharmacology

Volumn , Issue SUPPL.61, 2013, Pages

  Nollet, Mathieu ^a,b,c   Le Guisquet, Anne Marie ^a   Belzung, Catherine ^a  

^a INSERM   (France)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Animal model; Antidepressants; Major depression

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 (2 CHLORO 4 METHOXY 5 METHYLPHENYL) N [2 CYCLOPROPYL 1 (3 FLUORO 4 METHYLPHENYL)ETHYL] 5 METHYL N (2 PROPYNYL) 2 THIAZOLAMINE; AMIBEGRON; ANTALARMIN; CHLORDIAZEPOXIDE; DESIPRAMINE; DIZOCILPINE; FLUOXETINE; IMIPRAMINE; MAPROTILINE; MORPHINE; NELIVAPTAN; PINDOLOL; RIMONABANT; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SULPIRIDE; TRAMADOL; YOHIMBINE;

ARTICLE; BEHAVIOR; BODY WEIGHT; CHRONIC STRESS; COGNITION; EXPERIMENTAL MODEL; GENETIC ASSOCIATION; MAJOR DEPRESSION; MOLECULAR PATHOLOGY; MOUSE; MOUSE STRAIN; NEUROBIOLOGY; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RISK FACTOR; UNPREDICTABLE CHRONIC MILD STRESS; ANIMAL; ANIMAL BEHAVIOR; BAGG ALBINO MOUSE; DEPRESSION; DISEASE MODEL; MENTAL STRESS; PSYCHOLOGICAL ASPECT; RAT; PSYCHOLOGY;

ANIMALS; BEHAVIOR, ANIMAL; DEPRESSION; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED BALB C; RATS; STRESS, PSYCHOLOGICAL;

EID: 84883201199     PISSN: 19348282     EISSN: 19348290     Source Type: Journal    
DOI: 10.1002/0471141755.ph0565s61     Document Type: Article

References (32)

1. Aickin, M. and Gensler, H. 1996. Adjusting for multiple testing when reporting research results: TheBonferroni vs.Holmmethods.Am. J. Public Health 86:726-728.
2. Alonso, R., Griebel, G., Pavone, G., Stemmelin, J., le, F.G., and Soubrie, P. 2004. Blockade of CRF(1) or V(1b) receptors reverses stressinduced suppression of neurogenesis in a mouse model of depression. Mol. Psychiatry 9:278-286, 224.
3. Belzung, C. and Lemoine, M. 2011. Criteria of validity for animal models of psychiatric disorders: Focus on anxiety disorders and depression. Biol. Mood Anxiety Disord. 1:9.
4. Caspi, A., Sugden, K., Moffitt, T.E., Taylor, A., Craig, I.W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., and Poulton, R. 2003. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 301:386-389.
5. Deacon, R.M. 2006. Assessing nest building in mice. Nat. Protoc. 1:1117-1119.
6. Ducottet, C. and Belzung, C. 2005. Correlations between behaviours in the elevated plus-maze and sensitivity to unpredictable subchronic mild stress: Evidence from inbred strains of mice. Behav. Brain Res. 156:153-162.
7. Ducottet, C., Griebel, G., and Belzung, C. 2003. Effects of the selective nonpeptide corticotropinreleasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry 27:625-631.
8. Griebel, G., Simiand, J., Serradeil-Le, G.C., Wagnon, J., Pascal, M., Scatton, B., Maffrand, J.P., and Soubrie, P. 2002. Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc. Natl. Acad. Sci. U.S.A 99:6370-6375.
9. Griebel, G., Stemmelin, J., and Scatton, B. 2005. Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. Biol. Psychiatry 57:261-267.
10. Ibarguen-Vargas, Y., Surget, A., Touma, C., Palme, R., and Belzung, C. 2008. Multifaceted strainspecific effects in a mouse model of depression and of antidepressant reversal. Psychoneuroendocrinology 33:1357-1368.
11. Isingrini, E., Camus, V., Le Guisquet, A.M., Pingaud, M., Devers, S., and Belzung, C. 2010. Association between repeated unpredictable chronic mild stress (UCMS) procedures with a high fat diet: A model of fluoxetine resistance in mice. PLoS One 5:e10404.
12. Kalueff, A.V. and Tuohimaa, P. 2004a. Contrasting grooming phenotypes in C57Bl/6 and 129S1/SvImJ mice. Brain Res. 1028:75-82.
13. Kalueff, A.V. and Tuohimaa, P. 2004b. Grooming analysis algorithm for neurobehavioural stress research. Brain Res. Brain Res. Protoc. 13:151-158.
14. Katz, R.J. 1982. Animal model of depression: Pharmacological sensitivity of a hedonic deficit. Pharmacol. Biochem. Behav. 16:965-968.
15. Kendler, K.S., Gardner, C.O., and Prescott, C.A. 2002. Toward a comprehensive developmental model for major depression in women. Am. J. Psychiatry 159:1133-1145.
16. Muscat, R., Papp, M., and Willner, P. 1992. Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline. Psychopharmacology 109:433-438.
17. Nollet, M., Gaillard, P., Minier, F., Tanti, A., Belzung, C., and Leman, S. 2011. Activation of orexin neurons in dorsomedial/perifornical hypothalamus and antidepressant reversal in a rodent model of depression. Neuropharmacology 61:336-346.
18. Papp, M., Willner, P., and Muscat, R. 1991. An animal model of anhedonia: Attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress. Psychopharmacology 104:255-259.
19. Papp, M.,Muscat, R., andWillner, P. 1992. Subsensitivity to dopamine agonists following chronic unpredictable mild stress. J. Psychopharmacol. 6:116.
20. Pothion, S., Bizot, J.C., Trovero, F., and Belzung, C. 2004. Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress. Behav. Brain Res. 155:135-146.
21. Sibille, E., Wang, Y., Joeyen-Waldorf, J., Gaiteri, C., Surget, A., Oh, S., Belzung, C., Tseng, G.C., and Lewis, D.A. 2009. A molecular signature of depression in the amygdala. Am. J. Psychiatry 166:1011-1024.
22. Stemmelin, J., Cohen, C., Terranova, J.P., Lopez-Grancha, M., Pichat, P., Bergis, O., Decobert, M., Santucci, V., Francon, D., Alonso, R., Stahl, S.M., Keane, P., Avenet, P., Scatton, B., le, F.G., and Griebel, G. 2008. Stimulation of the beta3-adrenoceptor as a novel treatment strategy for anxiety and depressive disorders. Neuropsychopharmacology 33:574-587.
23. Surget, A. and Belzung, C. 2009. Unpredictable chronicmild stress in mice. In Experimental Animal Models in Neurobehavioral Research (A.V. Kalueff andJ.L. LaPorte, eds.) pp. 79-112. Nova Science Publishers, New York.
24. Surget, A., Saxe, M., Leman, S., Ibarguen-Vargas, Y., Chalon, S., Griebel, G., Hen, R., and Belzung, C. 2008. Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol. Psychiatry 64:293-301.
25. Surget, A., Wang, Y., Leman, S., Ibarguen-Vargas, Y., Edgar, N., Griebel, G., Belzung, C., and Sibille, E. 2009. Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal. Neuropsychopharmacology 34:1363-1380.
26. Surget, A., Tanti, A., Leonardo, E.D., Laugeray, A., Rainer, Q., Touma, C., Palme, R., Griebel, G., Ibarguen-Vargas, Y., Hen, R., and Belzung, C. 2011. Antidepressants recruit new neurons to improve stress response regulation. Mol. Psychiatry 16:1177-1188.
27. Willner, P. 1997. Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation. Psychopharmacology 134:319-329.
28. Willner, P., and Mitchell, P.J. 2002. The validity of animal models of predisposition to depression. Behav. Pharmacol. 13:169-188.
29. Willner, P., Towell, A., Sampson, D., Sophokleous, S., and Muscat, R. 1987. Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology 93:358-364.
30. Willner, P., Muscat, R., and Papp, M. 1992. Chronic mild stress-induced anhedonia: A realistic animal model of depression. Neurosci. Biobehav. Rev. 16:525-534.
31. Yalcin, I., Aksu, F., and Belzung, C. 2005. Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol. Eur. J. Pharmacol. 514:165-174.
32. Yalcin, I., Belzung, C., and Surget, A. 2008. Mouse strain differences in the unpredictable chronic mild stress: A four-antidepressant survey. Behav. Brain Res. 193:140-143.