메뉴 건너뛰기




Volumn 20, Issue 3, 2015, Pages 289-297

The molecular genetic architecture of attention deficit hyperactivity disorder

Author keywords

[No Author keywords available]

Indexed keywords

ATTENTION DEFICIT DISORDER; BIOINFORMATICS; CADHERIN 13 GENE; CASE CONTROL STUDY; COPY NUMBER VARIATION; DRD4 GENE; DRD5 GENE; ENDOPHENOTYPE; GENE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC RISK; GENETIC VARIABILITY; GIT1 GENE; GLUCOSE FRUCTOSE OXIDOREDUCTASE DOMAIN 1 GENE; GLUTAMATE RECEPTOR 1 GENE; GLUTAMATE RECEPTOR 5 GENE; GLUTAMATE RECEPTOR 7 GENE; GLUTAMATE RECEPTOR 8 GENE; HTR1B GENE; HUMAN; LPHN3 GENE; MENTAL DISEASE; MOLECULAR GENETICS; NOS1 GENE; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE TRAIT; REVIEW; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM; SLC6A3 GENE; SLC6A4 GENE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25 GENE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY;

EID: 84924726491     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2014.183     Document Type: Review
Times cited : (181)

References (103)
  • 1
    • 0027272196 scopus 로고
    • Adult outcome of hyperactive boys educational achievement, occupational rank, and psychiatric status
    • Mannuzza S, Klein RG, Bessler A, Malloy P, LaPadula M. Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. Arch Gen Psychiatry 1993; 50: 565-576
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 565-576
    • Mannuzza, S.1    Klein, R.G.2    Bessler, A.3    Malloy, P.4    La Padula, M.5
  • 2
    • 84919635331 scopus 로고    scopus 로고
    • An epidemiological studysubstance use, and comorbid problems in incarcerated women of adhd, substance use, and comorbid problems in incarcerated women in sweden
    • Konstenius M, Larsson H, Lundholm L, Philips B, Glind GV, Jayaram-Lindström N, et al. An epidemiological studysubstance use, and comorbid problems in incarcerated women of ADHD, substance use, and comorbid problems in incarcerated women in Sweden. J Atten Disord 2012; 19: 44-52
    • (2012) J Atten Disord , vol.19 , pp. 44-52
    • Konstenius, M.1    Larsson, H.2    Lundholm, L.3    Philips, B.4    Glind, G.V.5    Jayaram-Lindström, N.6
  • 3
    • 0030917123 scopus 로고    scopus 로고
    • Attention-deficit hyperactivity disorder: A category or a continuum? Genetic analysis of a large-scale twin study
    • Levy F, Hay DA, McStephen M, Wood C, Waldman I. Attention-deficit hyperactivity disorder: a category or a continuum? Genetic analysis of a large-scale twin study. J Am Acad Child Adolesc Psychiatry 1997; 36: 737-744
    • (1997) J Am Acad Child Adolesc Psychiatry , vol.36 , pp. 737-744
    • Levy, F.1    Hay, D.A.2    McStephen, M.3    Wood, C.4    Waldman, I.5
  • 5
    • 0027407565 scopus 로고
    • Apolipoprotein e: High-Avidity binding to beta-Amyloid and increased frequency of type 4 allele in late-onset familial alzheimer disease
    • Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, et al. Apolipoprotein E: high-Avidity binding to beta-Amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993; 90: 1977-1981
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3    Pericak-Vance, M.4    Enghild, J.5    Salvesen, G.S.6
  • 6
    • 55549147191 scopus 로고    scopus 로고
    • Personal genomes: The case of the missing heritability
    • Maher B. Personal genomes: the case of the missing heritability. Nature 2008; 456: 18-21
    • (2008) Nature , vol.456 , pp. 18-21
    • Maher, B.1
  • 7
    • 77049120173 scopus 로고    scopus 로고
    • The genetics of autism: Key issues, recent findings, and clinical implications
    • El-Fishawy P, State MW. The genetics of autism: key issues, recent findings, and clinical implications. Psychiatr Clin North Am 2010; 33: 83-105
    • (2010) Psychiatr Clin North Am , vol.33 , pp. 83-105
    • El-Fishawy, P.1    State, M.W.2
  • 8
    • 79959503826 scopus 로고    scopus 로고
    • The international hapmap project
    • International HapMap Consortium. The International HapMap Project. Nature 2003; 426: 789-796
    • (2003) Nature , vol.426 , pp. 789-796
    • Hapmap Consortium, I.1
  • 9
    • 84905042733 scopus 로고    scopus 로고
    • Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders
    • Kenny EM, Cormican P, Furlong S, Heron E, Kenny G, Fahey C, et al. Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders. Mol Psychiatry 2013; 19: 872-879
    • (2013) Mol Psychiatry , vol.19 , pp. 872-879
    • Kenny, E.M.1    Cormican, P.2    Furlong, S.3    Heron, E.4    Kenny, G.5    Fahey, C.6
  • 10
    • 84862833585 scopus 로고    scopus 로고
    • Exome sequencing and unrelated findings in the context of complex disease research: Ethical and clinical implications
    • Lyon GJ, Jiang T, Van Wijk R, Wang W, Bodily PM, Xing J, et al. Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discov Med 2011; 12: 41-55
    • (2011) Discov Med , vol.12 , pp. 41-55
    • Lyon, G.J.1    Jiang, T.2    Van Wijk, R.3    Wang, W.4    Bodily, P.M.5    Xing, J.6
  • 11
    • 44649128381 scopus 로고    scopus 로고
    • Avenues for pharmacogenetic research in adhd
    • In Fitzgerald M, Bellgrove M, Gill M (eds John Wiley & Sons, Ltd
    • Barry E, Hawi Z, Kirlet A. Avenues for pharmacogenetic research in ADHD. In: Fitzgerald M, Bellgrove M, Gill M (eds). A handbook of Attention Deficit Hyperactivity Disorder. John Wiley & Sons, Ltd, 2007, pp 357-358
    • (2007) A Handbook of Attention Deficit Hyperactivity Disorder , pp. 357-358
    • Barry, E.1    Hawi, Z.2    Kirlet, A.3
  • 12
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 1996; 379: 606-612
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 13
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 1999; 283: 397-401
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1    Wetsel, W.C.2    Jones, S.R.3    Levin, E.D.4    Jaber, M.5    Caron, M.G.6
  • 14
    • 0033958141 scopus 로고    scopus 로고
    • The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in vitro by the superfusion slice technique
    • Russell VA. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in vitro by the superfusion slice technique. Neurosci Biobehav Rev 2000; 24: 133-136
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 133-136
    • Russell, V.A.1
  • 15
    • 0035754156 scopus 로고    scopus 로고
    • The vntr polymorphism of the human dopamine transporter (dat1) gene affects gene expression
    • Fuke S, Suo S, Takahashi N, Koike H, Sasagawa N, Ishiura S. The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression. Pharmacogenomics J 2001; 1: 152-156
    • (2001) Pharmacogenomics J , vol.1 , pp. 152-156
    • Fuke, S.1    Suo, S.2    Takahashi, N.3    Koike, H.4    Sasagawa, N.5    Ishiura, S.6
  • 16
    • 84879507861 scopus 로고    scopus 로고
    • Functional genomics of attention-deficit/hyperactivity disorder (adhd) risk alleles on dopamine transporter binding in adhd and healthy control subjects
    • Spencer TJ, Biederman J, Faraone S V, Madras BK, Bonab A, Dougherty DD, et al. Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects. Biol Psychiatry 2013; 74: 84-89
    • (2013) Biol Psychiatry , vol.74 , pp. 84-89
    • Spencer, T.J.1    Biederman, J.2    Faraone, S.V.3    Madras, B.K.4    Bonab, A.5    Dougherty, D.D.6
  • 17
    • 84893681339 scopus 로고    scopus 로고
    • Relating dopaminergic and cholinergic polymorphisms to spatial attention in infancy
    • Markant J, Cicchetti D, Hetzel S, Thomas KM. Relating dopaminergic and cholinergic polymorphisms to spatial attention in infancy. Dev Psychol 2014; 50: 360-369
    • (2014) Dev Psychol , vol.50 , pp. 360-369
    • Markant, J.1    Cicchetti, D.2    Hetzel, S.3    Thomas, K.M.4
  • 21
    • 84863116416 scopus 로고    scopus 로고
    • Investigating the contribution of common genetic variants to the risk and pathogenesis of adhd
    • Stergiakouli E, Hamshere M, Holmans P, Langley K, Zaharieva I, Hawi Z, et al. Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. Am J Psychiatry 2012; 169: 186-194
    • (2012) Am J Psychiatry , vol.169 , pp. 186-194
    • Stergiakouli, E.1    Hamshere, M.2    Holmans, P.3    Langley, K.4    Zaharieva, I.5    Hawi, Z.6
  • 22
    • 84879333186 scopus 로고    scopus 로고
    • Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome-wide association study of both common and rare variants
    • Yang L, Neale BM, Liu L, Lee SH, Wray NR, Ji N, et al. Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. Am J Med Genet B Neuropsychiatr Genet 2013; 162B: 419-430
    • (2013) Am J Med Genet B Neuropsychiatr Genet , vol.162 B , pp. 419-430
    • Yang, L.1    Neale, B.M.2    Liu, L.3    Lee, S.H.4    Wray, N.R.5    Ji, N.6
  • 25
    • 57349087863 scopus 로고    scopus 로고
    • Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations
    • Lasky-Su J, Neale BM, Franke B, Anney RJL, Zhou K, Maller JB, et al. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 1345-1354
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1345-1354
    • Lasky-Su, J.1    Neale, B.M.2    Franke, B.3    Anney, R.J.L.4    Zhou, K.5    Maller, J.B.6
  • 26
    • 55349128167 scopus 로고    scopus 로고
    • Molecular genetics of adult adhd: Converging evidence from genome-wide association and extended pedigree linkage studies
    • Lesch K-P, Timmesfeld N, Renner TJ, Halperin R, Röser C, Nguyen TT, et al. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. J Neural Transm 2008; 115: 1573-1585
    • (2008) J Neural Transm , vol.115 , pp. 1573-1585
    • Lesch, K.-P.1    Timmesfeld, N.2    Renner, T.J.3    Halperin, R.4    Röser, C.5    Nguyen, T.T.6
  • 27
  • 29
    • 46349103630 scopus 로고    scopus 로고
    • Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings
    • Zhou K, Asherson P, Sham P, Franke B, Anney RJL, Buitelaar J, et al. Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings. Biol Psychiatry 2008; 64: 571-576
    • (2008) Biol Psychiatry , vol.64 , pp. 571-576
    • Zhou, K.1    Asherson, P.2    Sham, P.3    Franke, B.4    Anney, R.J.L.5    Buitelaar, J.6
  • 30
    • 0034066303 scopus 로고    scopus 로고
    • Expression of t-cadherin (cdh13, h-cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells
    • Takeuchi T, Misaki A, Liang SB, Tachibana A, Hayashi N, Sonobe H, et al. Expression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells. J Neurochem 2000; 74: 1489-1497
    • (2000) J Neurochem , vol.74 , pp. 1489-1497
    • Takeuchi, T.1    Misaki, A.2    Liang, S.B.3    Tachibana, A.4    Hayashi, N.5    Sonobe, H.6
  • 31
    • 34249785945 scopus 로고    scopus 로고
    • Meta-Analysis of structural imaging findings in attention-deficit/hyperactivity disorder
    • Valera EM, Faraone S V, Murray KE, Seidman LJ. Meta-Analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biol Psychiatry 2007; 61: 1361-1369
    • (2007) Biol Psychiatry , vol.61 , pp. 1361-1369
    • Valera, E.M.1    Faraone, S.V.2    Murray, K.E.3    Seidman, L.J.4
  • 32
    • 84655176643 scopus 로고    scopus 로고
    • Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder
    • Elia J, Glessner JT, Wang K, Takahashi N, Shtir CJ, Hadley D, et al. Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nat Genet 2012; 44: 78-84
    • (2012) Nat Genet , vol.44 , pp. 78-84
    • Elia, J.1    Glessner, J.T.2    Wang, K.3    Takahashi, N.4    Shtir, C.J.5    Hadley, D.6
  • 33
    • 79959923522 scopus 로고    scopus 로고
    • G:profiler-A web server for functional interpretation of gene lists (2011 update
    • Reimand J, Arak T, Vilo J. g:Profiler-A web server for functional interpretation of gene lists (2011 update). Nucleic Acids Res 2011; 39: W307-W315
    • (2011) Nucleic Acids Res , vol.39 , pp. W307-W315
    • Reimand, J.1    Arak, T.2    Vilo, J.3
  • 34
    • 79955135758 scopus 로고    scopus 로고
    • Integrated genome-wide association study findings: Identification of a neurodevelopmental network for attention deficit hyperactivity disorder
    • Poelmans G, Pauls DL, Buitelaar JK, Franke B. Integrated genome-wide association study findings: identification of a neurodevelopmental network for attention deficit hyperactivity disorder. Am J Psychiatry 2011; 168: 365-377
    • (2011) Am J Psychiatry , vol.168 , pp. 365-377
    • Poelmans, G.1    Pauls, D.L.2    Buitelaar, J.K.3    Franke, B.4
  • 35
    • 77949831756 scopus 로고    scopus 로고
    • Structural variation in the human genome and its role in disease
    • Stankiewicz P, Lupski JR. Structural variation in the human genome and its role in disease. Annu Rev Med 2010; 61: 437-455
    • (2010) Annu Rev Med , vol.61 , pp. 437-455
    • Stankiewicz, P.1    Lupski, J.R.2
  • 36
    • 54049144653 scopus 로고    scopus 로고
    • Copy-number variations associated with neuropsychiatric conditions
    • Cook EH, Scherer SW. Copy-number variations associated with neuropsychiatric conditions. Nature 2008; 455: 919-923
    • (2008) Nature , vol.455 , pp. 919-923
    • Cook, E.H.1    Scherer, S.W.2
  • 37
    • 77952887857 scopus 로고    scopus 로고
    • Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes
    • Elia J, Gai X, Xie HM, Perin JC, Geiger E, Glessner JT, et al. Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Mol Psychiatry 2010; 15: 637-646
    • (2010) Mol Psychiatry , vol.15 , pp. 637-646
    • Elia, J.1    Gai, X.2    Xie, H.M.3    Perin, J.C.4    Geiger, E.5    Glessner, J.T.6
  • 38
    • 78049303903 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis
    • Williams NM, Zaharieva I, Martin A, Langley K, Mantripragada K, Fossdal R, et al. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet 2010; 376: 1401-1408
    • (2010) Lancet , vol.376 , pp. 1401-1408
    • Williams, N.M.1    Zaharieva, I.2    Martin, A.3    Langley, K.4    Mantripragada, K.5    Fossdal, R.6
  • 40
    • 84863116701 scopus 로고    scopus 로고
    • Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: The role of rare variants and duplications at 15q13.3
    • Williams NM, Franke B, Mick E, Anney RJL, Freitag CM, Gill M, et al. Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry 2012; 169: 195-204
    • (2012) Am J Psychiatry , vol.169 , pp. 195-204
    • Williams, N.M.1    Franke, B.2    Mick, E.3    Anney, R.J.L.4    Freitag, C.M.5    Gill, M.6
  • 41
    • 84891165697 scopus 로고    scopus 로고
    • Genome-wide analysis of rare copy number variations reveals park2 as a candidate gene for attention-deficit/hyperactivity disorder
    • Jarick I, Volckmar AL, Pütter C, Pechlivanis S, Nguyen TT, Dauvermann MR, et al. Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder. Mol Psychiatry 2014; 19: 115-121
    • (2014) Mol Psychiatry , vol.19 , pp. 115-121
    • Jarick, I.1    Volckmar, A.L.2    Pütter, C.3    Pechlivanis, S.4    Nguyen, T.T.5    Dauvermann, M.R.6
  • 42
    • 79955470881 scopus 로고    scopus 로고
    • Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: Association with neuropeptide y gene dosage in an extended pedigree
    • Lesch K-P, Selch S, Renner TJ, Jacob C, Nguyen TT, Hahn T, et al. Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree. Mol Psychiatry 2011; 16: 491-503
    • (2011) Mol Psychiatry , vol.16 , pp. 491-503
    • Lesch, K.-P.1    Selch, S.2    Renner, T.J.3    Jacob, C.4    Nguyen, T.T.5    Hahn, T.6
  • 44
    • 84866366581 scopus 로고    scopus 로고
    • Leveraging the cortical cholinergic system to enhance attention
    • Demeter E, Sarter M. Leveraging the cortical cholinergic system to enhance attention. Neuropharmacology 2013; 64: 294-304
    • (2013) Neuropharmacology , vol.64 , pp. 294-304
    • Demeter, E.1    Sarter, M.2
  • 48
    • 58149163446 scopus 로고    scopus 로고
    • Tissue-specific genetic control of splicing: Implications for the study of complex traits
    • Heinzen EL, Ge D, Cronin KD, Maia JM, Shianna K V, Gabriel WN, et al. Tissue-specific genetic control of splicing: implications for the study of complex traits. PLoS Biol 2008; 6: e1
    • (2008) PLoS Biol , vol.6 , pp. e1
    • Heinzen, E.L.1    Ge, D.2    Cronin, K.D.3    Maia, J.M.4    Shianna, K.V.5    Gabriel, W.N.6
  • 49
    • 84860210990 scopus 로고    scopus 로고
    • Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity
    • Tovo-Rodrigues L, Rohde LA, Roman T, Schmitz M, Polanczyk G, Zeni C, et al. Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity. Mol Psychiatry 2012; 17: 520-526
    • (2012) Mol Psychiatry , vol.17 , pp. 520-526
    • Tovo-Rodrigues, L.1    Rohde, L.A.2    Roman, T.3    Schmitz, M.4    Polanczyk, G.5    Zeni, C.6
  • 50
    • 84894068787 scopus 로고    scopus 로고
    • Drd4 rare variants in attention-deficit/hyperactivity disorder (adhd): Further evidence from a birth cohort study
    • Tovo-Rodrigues L, Rohde L, Menezes AMB, Polanczyk GV, Kieling C, Genro JP, et al. DRD4 rare variants in Attention-Deficit/Hyperactivity Disorder (ADHD): further evidence from a birth cohort study. PLoS One 2013; 8: e85164
    • (2013) PLoS One , vol.8 , pp. e85164
    • Tovo-Rodrigues, L.1    Rohde, L.2    Menezes, A.M.B.3    Polanczyk, G.V.4    Kieling, C.5    Genro, J.P.6
  • 52
    • 41849124886 scopus 로고    scopus 로고
    • Evidence for overlapping genetic influences on autistic and adhd behaviours in a community twin sample
    • Ronald A, Simonoff E, Kuntsi J, Asherson P, Plomin R. Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry 2008; 49: 535-542
    • (2008) J Child Psychol Psychiatry , vol.49 , pp. 535-542
    • Ronald, A.1    Simonoff, E.2    Kuntsi, J.3    Asherson, P.4    Plomin, R.5
  • 55
    • 38349106160 scopus 로고    scopus 로고
    • Comparative genome hybridization suggests a role for nrxn1 and apba2 in schizophrenia
    • Kirov G, Gumus D, Chen W, Norton N, Georgieva L, Sari M, et al. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet 2008; 17: 458-465
    • (2008) Hum Mol Genet , vol.17 , pp. 458-465
    • Kirov, G.1    Gumus, D.2    Chen, W.3    Norton, N.4    Georgieva, L.5    Sari, M.6
  • 56
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium 9875
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders : a genome-wide analysis. Lancet 2013; 381(9875): 1371-1379
    • (2013) Lancet , vol.381 , pp. 1371-1379
  • 57
    • 78549252909 scopus 로고    scopus 로고
    • Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility
    • O'Dushlaine C, Kenny E, Heron E, Donohoe G, Gill M, Morris D, et al. Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility. Mol Psychiatry 2011; 16: 286-292
    • (2011) Mol Psychiatry , vol.16 , pp. 286-292
    • O'Dushlaine, C.1    Kenny, E.2    Heron, E.3    Donohoe, G.4    Gill, M.5    Morris, D.6
  • 58
    • 0012789869 scopus 로고    scopus 로고
    • Allelic variation in gene expression is common in the human genome
    • Lo HS, Wang Z, Hu Y, Yang HH, Gere S, Buetow KH, et al. Allelic variation in gene expression is common in the human genome. Genome Res 2003; 13: 1855-1862
    • (2003) Genome Res , vol.13 , pp. 1855-1862
    • Lo, H.S.1    Wang, Z.2    Hu, Y.3    Yang, H.H.4    Gere, S.5    Buetow, K.H.6
  • 60
    • 57749200718 scopus 로고    scopus 로고
    • Promoter polymorphisms in ace (angiotensin i-converting enzyme) associated with clinical outcomes in hypertension
    • Johnson A D, Gong Y, Wang D, Langaee TY, Shin J, Cooper-Dehoff RM, et al. Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. Clin Pharmacol Ther 2009; 85: 36-44
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 36-44
    • Johnson, A.D.1    Gong, Y.2    Wang, D.3    Langaee, T.Y.4    Shin, J.5    Cooper-Dehoff, R.M.6
  • 61
    • 42649123990 scopus 로고    scopus 로고
    • Sizing up human height variation
    • Visscher PM. Sizing up human height variation. Nat Genet 2008; 40: 489-490
    • (2008) Nat Genet , vol.40 , pp. 489-490
    • Visscher, P.M.1
  • 65
    • 0035825219 scopus 로고    scopus 로고
    • Endophenotypes as quantitative risk factors for psychiatric disease: Rationale and study design
    • Almasy L, Blangero J. Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet 2001; 105: 42-44
    • (2001) Am J Med Genet , vol.105 , pp. 42-44
    • Almasy, L.1    Blangero, J.2
  • 66
    • 0036674495 scopus 로고    scopus 로고
    • Neuroscience of attention-deficit/hyperactivity disorder: The search for endophenotypes
    • Castellanos FX, Tannock R. Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes. Nat Rev Neurosci 2002; 3: 617-628
    • (2002) Nat Rev Neurosci , vol.3 , pp. 617-628
    • Castellanos, F.X.1    Tannock, R.2
  • 67
    • 84897058188 scopus 로고    scopus 로고
    • Explaining additional genetic variation in complex traits
    • Robinson MR, Wray NR, Visscher PM. Explaining additional genetic variation in complex traits. Trends Genet 2014; 30: 124-132
    • (2014) Trends Genet , vol.30 , pp. 124-132
    • Robinson, M.R.1    Wray, N.R.2    Visscher, P.M.3
  • 68
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636-645
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 69
    • 1642327634 scopus 로고    scopus 로고
    • Familial clustering of latent class and dsm-iv defined attention-deficit/hyperactivity disorder (adhd) subtypes
    • Rasmussen ER, Neuman RJ, Heath AC, Levy F, Hay DA, Todd RD. Familial clustering of latent class and DSM-IV defined attention-deficit/hyperactivity disorder (ADHD) subtypes. J Child Psychol Psychiatry 2004; 45: 589-598
    • (2004) J Child Psychol Psychiatry , vol.45 , pp. 589-598
    • Rasmussen, E.R.1    Neuman, R.J.2    Heath, A.C.3    Levy, F.4    Hay, D.A.5    Todd, R.D.6
  • 70
    • 0031469587 scopus 로고    scopus 로고
    • Genetic analysis of simulated oligogenic traits in nuclear and extended pedigrees: Summary of gaw10 contributions
    • Wijsman EM, Amos CI. Genetic analysis of simulated oligogenic traits in nuclear and extended pedigrees: summary of GAW10 contributions. Genet Epidemiol 1997; 14: 719-735
    • (1997) Genet Epidemiol , vol.14 , pp. 719-735
    • Wijsman, E.M.1    Amos, C.I.2
  • 72
    • 20444423267 scopus 로고    scopus 로고
    • Statistical approaches to complex phenotypes: Evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder
    • Waldman ID. Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder. Biol Psychiatry 2005; 57: 1347-1356
    • (2005) Biol Psychiatry , vol.57 , pp. 1347-1356
    • Waldman, I.D.1
  • 74
    • 0035085502 scopus 로고    scopus 로고
    • Psychological mechanisms in hyperactivity: II. The role of genetic factors
    • Kuntsi J, Stevenson J. Psychological mechanisms in hyperactivity: II. The role of genetic factors. J Child Psychol Psychiatry 2001; 42: 211-219
    • (2001) J Child Psychol Psychiatry , vol.42 , pp. 211-219
    • Kuntsi, J.1    Stevenson, J.2
  • 75
    • 36048957548 scopus 로고    scopus 로고
    • Reaction time performance in adhd: Improvement under fast-incentive condition and familial effects
    • Andreou P, Neale BM, Chen W, Christiansen H, Gabriels I, Heise A, et al. Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects. Psychol Med 2007; 37: 1703-1715
    • (2007) Psychol Med , vol.37 , pp. 1703-1715
    • Andreou, P.1    Neale, B.M.2    Chen, W.3    Christiansen, H.4    Gabriels, I.5    Heise, A.6
  • 76
    • 0035171492 scopus 로고    scopus 로고
    • Deficient inhibition as a marker for familial adhd
    • Crosbie J, Schachar R. Deficient inhibition as a marker for familial ADHD. Am J Psychiatry 2001; 158: 1884-1890
    • (2001) Am J Psychiatry , vol.158 , pp. 1884-1890
    • Crosbie, J.1    Schachar, R.2
  • 77
    • 84879463049 scopus 로고    scopus 로고
    • Response inhibition and adhd traits: Correlates and heritability in a community sample
    • Crosbie J, Arnold P, Paterson A, Swanson J, Dupuis A, Li X, et al. Response inhibition and ADHD traits: correlates and heritability in a community sample. J Abnorm Child Psychol 2013; 41: 497-507
    • (2013) J Abnorm Child Psychol , vol.41 , pp. 497-507
    • Crosbie, J.1    Arnold, P.2    Paterson, A.3    Swanson, J.4    Dupuis, A.5    Li, X.6
  • 78
    • 84894493490 scopus 로고    scopus 로고
    • The persistence of cognitive deficits in remitted and unremitted adhd: A case for the state-independence of response inhibition
    • McAuley T, Crosbie J, Charach A, Schachar R. The persistence of cognitive deficits in remitted and unremitted ADHD: a case for the state-independence of response inhibition. J Child Psychol Psychiatry 2014; 55: 292-300
    • (2014) J Child Psychol Psychiatry , vol.55 , pp. 292-300
    • McAuley, T.1    Crosbie, J.2    Charach, A.3    Schachar, R.4
  • 79
    • 70449625249 scopus 로고    scopus 로고
    • Duration discrimination in the range of milliseconds and seconds in children with adhd and their unaffected siblings
    • Himpel S, Banaschewski T, Grüttner A, Becker A, Heise A, Uebel H, et al. Duration discrimination in the range of milliseconds and seconds in children with ADHD and their unaffected siblings. Psychol Med 2009; 39: 1745-1751
    • (2009) Psychol Med , vol.39 , pp. 1745-1751
    • Himpel, S.1    Banaschewski, T.2    Grüttner, A.3    Becker, A.4    Heise, A.5    Uebel, H.6
  • 80
    • 84939889205 scopus 로고    scopus 로고
    • Moderators of neuropsychological mechanism in attention- deficit hyperactivity disorder
    • e-pub ahead of print July
    • Nikolas MA, Nigg JT. Nikolas MA, Nigg JT. Moderators of neuropsychological mechanism in attention- deficit hyperactivity disorder. J Abnorm Child Psychol; e-pub ahead of print July 20 2014
    • (2014) J Abnorm Child Psychol , vol.20
    • Nikolas, M.A.1    Nigg, J.T.2    Nikolas, M.A.3    Nigg, J.T.4
  • 83
    • 78649895019 scopus 로고    scopus 로고
    • Atypical default network connectivity in youth with attention-deficit/hyperactivity disorder
    • Fair DA, Posner J, Nagel BJ, Bathula D, Dias TGC, Mills KL, et al. Atypical default network connectivity in youth with attention-deficit/hyperactivity disorder. Biol Psychiatry 2010; 68: 1084-1091
    • (2010) Biol Psychiatry , vol.68 , pp. 1084-1091
    • Fair, D.A.1    Posner, J.2    Nagel, B.J.3    Bathula, D.4    Dias, T.G.C.5    Mills, K.L.6
  • 85
    • 24944521591 scopus 로고    scopus 로고
    • Dissecting the attention deficit hyperactivity disorder (adhd) phenotype: Sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (dat1) genotype
    • Bellgrove MA, Hawi Z, Kirley A, Gill M, Robertson IH. Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: Sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype. Neuropsychologia 2005; 43: 1847-1857
    • (2005) Neuropsychologia , vol.43 , pp. 1847-1857
    • Bellgrove, M.A.1    Hawi, Z.2    Kirley, A.3    Gill, M.4    Robertson, I.H.5
  • 86
    • 51449092787 scopus 로고    scopus 로고
    • Absence of the 7-repeat variant of the drd4 vntr is associated with drifting sustained attention in children with adhd but not in controls
    • Johnson KA, Kelly SP, Robertson IH, Barry E, Mulligan A, Daly M, et al. Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 927-937
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 927-937
    • Johnson, K.A.1    Kelly, S.P.2    Robertson, I.H.3    Barry, E.4    Mulligan, A.5    Daly, M.6
  • 87
    • 57349101889 scopus 로고    scopus 로고
    • Snps in dopamine d2 receptor gene (drd2) and norepinephrine transporter gene (net) are associated with continuous performance task (cpt) phenotypes in adhd children and their families
    • Kollins SH, Anastopoulos AD, Lachiewicz AM, FitzGerald D, Morrissey-Kane E, Garrett ME, et al. SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 1580-1588
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 1580-1588
    • Kollins, S.H.1    Anastopoulos, A.D.2    Lachiewicz, A.M.3    Fitzgerald, D.4    Morrissey-Kane, E.5    Garrett, M.E.6
  • 88
    • 84855856978 scopus 로고    scopus 로고
    • Neuropsychological intra-individual variability explains unique genetic variance of adhd and shows suggestive linkage to chromosomes 12, 13, and 17
    • Frazier-Wood AC, Bralten J, Arias-Vasquez A, Luman M, Ooterlaan J, Sergeant J, et al. Neuropsychological intra-individual variability explains unique genetic variance of ADHD and shows suggestive linkage to chromosomes 12, 13, and 17. Am J Med Genet B Neuropsychiatr Genet 2012; 159B: 131-140
    • (2012) Am J Med Genet B Neuropsychiatr Genet , vol.159 B , pp. 131-140
    • Frazier-Wood, A.C.1    Bralten, J.2    Arias-Vasquez, A.3    Luman, M.4    Ooterlaan, J.5    Sergeant, J.6
  • 89
    • 84927174433 scopus 로고    scopus 로고
    • Alpha-2a adrenergic receptor gene variants are associated with increased intraindividual variability in response time
    • Cummins TDR, Jacoby O, Hawi Z, Nandam LS, Byrne MA V, Kim B-N, et al. Alpha-2A adrenergic receptor gene variants are associated with increased intraindividual variability in response time. Mol Psychiatry 2013; 19: 1031-1036
    • (2013) Mol Psychiatry , vol.19 , pp. 1031-1036
    • Cummins, T.D.R.1    Jacoby, O.2    Hawi, Z.3    Nandam, L.S.4    Byrne Ma, V.5    Kim, B.-N.6
  • 90
    • 84860148937 scopus 로고    scopus 로고
    • Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with adhd
    • Fair DA, Bathula D, Nikolas MA, Nigg JT. Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proc Natl Acad Sci USA 2012; 109: 6769-6774
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 6769-6774
    • Fair, D.A.1    Bathula, D.2    Nikolas, M.A.3    Nigg, J.T.4
  • 92
    • 67651121684 scopus 로고    scopus 로고
    • Candidate gene studies of adhd: A metaanalytic review
    • Gizer IR, Ficks C, Waldman ID. Candidate gene studies of ADHD: a metaanalytic review. Hum Genet 2009; 126: 51-90
    • (2009) Hum Genet , vol.126 , pp. 51-90
    • Gizer, I.R.1    Ficks, C.2    Waldman, I.D.3
  • 93
    • 0030133840 scopus 로고    scopus 로고
    • Dopamine d4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder
    • LaHoste GJ, Swanson JM, Wigal SB, Glabe C, Wigal T, King N, et al. Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder. Mol Psychiatry 1996; 1: 121-124
    • (1996) Mol Psychiatry , vol.1 , pp. 121-124
    • Lahoste, G.J.1    Swanson, J.M.2    Wigal, S.B.3    Glabe, C.4    Wigal, T.5    King, N.6
  • 94
    • 0032910655 scopus 로고    scopus 로고
    • Mapping susceptibility loci in attention deficit hyperactivity disorder: Preferential transmission of parental alleles at dat1
    • Daly G, Hawi Z, Fitzgerald M, Gill M. Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children. Mol Psychiatry 1999; 4: 192-196
    • (1999) DBH and DRD5 to Affected Children. Mol Psychiatry , vol.4 , pp. 192-196
    • Daly, G.1    Hawi, Z.2    Fitzgerald, M.3    Gill, M.4
  • 95
    • 0036024267 scopus 로고    scopus 로고
    • Family- based and association studies of monoamine oxidase a and attention deficit hyperactivity disorder (adhd preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (tova
    • Manor I, Tyano S, Mel E, Eisenberg J, Bachner-Melman R, Kotler M, et al. Family- based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (TOVA). Mol Psychiatry 2002; 7: 626-632
    • (2002) Mol Psychiatry , vol.7 , pp. 626-632
    • Manor, I.1    Tyano, S.2    Mel, E.3    Eisenberg, J.4    Bachner-Melman, R.5    Kotler, M.6
  • 96
    • 0036364966 scopus 로고    scopus 로고
    • Serotonergic system and attention deficit hyperactivity disorder (adhd): A potential susceptibility locus at the 5-ht(1b) receptor gene in 273 nuclear families from a multicentre sample
    • Hawi Z, Dring M, Kirley A, Foley D, Kent L, Craddock N, et al. Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multicentre sample. Mol Psychiatry 2002; 7: 718-725
    • (2002) Mol Psychiatry , vol.7 , pp. 718-725
    • Hawi, Z.1    Dring, M.2    Kirley, A.3    Foley, D.4    Kent, L.5    Craddock, N.6
  • 97
    • 0036384288 scopus 로고    scopus 로고
    • Synaptosomal-Associated protein 25 (snap-25) and attention deficit hyperactivity disorder (adhd): Evidence of linkage and association in the irish population
    • Brophy K, Hawi Z, Kirley A, Fitzgerald M, Gill M. Synaptosomal-Associated protein 25 (SNAP-25) and attention deficit hyperactivity disorder (ADHD): evidence of linkage and association in the Irish population. Mol Psychiatry 2002; 7: 913-917
    • (2002) Mol Psychiatry , vol.7 , pp. 913-917
    • Brophy, K.1    Hawi, Z.2    Kirley, A.3    Fitzgerald, M.4    Gill, M.5
  • 98
    • 0142178047 scopus 로고    scopus 로고
    • Disruption of a novel member of a sodium/hydrogen exchanger family and dock3 is associated with an attention deficit hyperactivity disorder-like phenotype
    • De Silva MG, Elliott K, Dahl H-H, Fitzpatrick E, Wilcox S, Delatycki M, et al. Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype. J Med Genet 2003; 40: 733-740
    • (2003) J Med Genet , vol.40 , pp. 733-740
    • De Silva, M.G.1    Elliott, K.2    Dahl, H.-H.3    Fitzpatrick, E.4    Wilcox, S.5    Delatycki, M.6
  • 99
    • 77954902187 scopus 로고    scopus 로고
    • A common variant of the latrophilin 3 gene, lphn3, confers susceptibility to adhd and predicts effectiveness of stimulant medication
    • Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, et al. A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication. Mol Psychiatry 2010; 15: 1053-1066
    • (2010) Mol Psychiatry , vol.15 , pp. 1053-1066
    • Arcos-Burgos, M.1    Jain, M.2    Acosta, M.T.3    Shively, S.4    Stanescu, H.5    Wallis, D.6
  • 101
    • 85027947415 scopus 로고    scopus 로고
    • Git1 is associated with adhd in humans and adhd-like behaviors in mice
    • Won H, Mah W, Kim E, Kim J-W, Hahm E-K, Kim M-H, et al. GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice. Nat Med 2011; 17: 566-572
    • (2011) Nat Med , vol.17 , pp. 566-572
    • Won, H.1    Mah, W.2    Kim, E.3    Kim, J.-W.4    Hahm, E.-K.5    Kim, M.-H.6
  • 102
    • 58149512668 scopus 로고    scopus 로고
    • Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans
    • Reif A, Jacob CP, Rujescu D, Herterich S, Lang S, Gutknecht L, et al. Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans. Arch Gen Psychiatry 2009; 66: 41-50
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 41-50
    • Reif, A.1    Jacob, C.P.2    Rujescu, D.3    Herterich, S.4    Lang, S.5    Gutknecht, L.6
  • 103
    • 67651113905 scopus 로고    scopus 로고
    • Genome-wide association studies in adhd
    • Franke B, Neale BM, Faraone S V. Genome-wide association studies in ADHD. Hum Genet 2009; 126: 13-50
    • (2009) Hum Genet , vol.126 , pp. 13-50
    • Franke, B.1    Neale, B.M.2    Faraone, S.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.