Expression of T-cadherin (CDH13, H-cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells

Journal of Neurochemistry

Volumn 74, Issue 4, 2000, Pages 1489-1497

  Takeuchi, Tamotsu ^a   Misaki, Akiko ^a   Liang, Sheng Ben ^a   Tachibana, Akiko ^b   Hayashi, Nakanobu ^b   Sonobe, Hiroshi ^a   Ohtsuki, Yuji ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b Progress Technologies Co Ltd   (Japan)

Author keywords

Brain; Epidermal growth factor; MA 511; Monoclonal antibody; Neuroblastoma; T cadherin

Indexed keywords

CADHERIN; CADHERIN T; EPIDERMAL GROWTH FACTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MA 511; UNCLASSIFIED DRUG;

ARTICLE; BRAIN REGION; CELL PROLIFERATION; CONTROLLED STUDY; GROWTH REGULATION; HUMAN; HUMAN TISSUE; MITOGENESIS; NERVE CELL GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANTIBODIES, MONOCLONAL; BLOTTING, NORTHERN; BRAIN CHEMISTRY; CADHERINS; CELL DIVISION; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0034066303     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0741489.x     Document Type: Article

References (16)

1. Asano K., Kubo O., Tajika Y., Huang M. C., Takakura K., Ebina K., and Suzuki S. (1997) Expression and role of cadherins in astrocytic tumors. Brain Tumor Pathol. 14, 27-33.
2. Carter B. S., Ewing C. M., Ward W. S., Treiger B. F., Aalder T. W., Schalken J. A., Epstein J. I., and Isaacs W. B. (1990) Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proc. Natl. Acad. Sci. USA 87, 8751-8755.
3. Fredette B. J., Miller J., and Ranscht B. (1996) Inhibition of motor axon growth by T-cadherin substrata. Development 122, 3163-3171.
4. Galfre G., Howe S. C., Milstein C., Butcher G. W., and Howard J. C. (1977) Antibodies to major histocompatibility antigen produced by hybrid cell lines. Nature 266, 550-552.
5. Lee S. W. (1996) H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat. Med. 2, 776-782.
6. Ranscht B. and Dours-Zimmermann M. T. (1991) T-cadherin, a novel cadherin cell adhesion molecule in the nervous system, lacks the conserved cytoplasmic region. Neuron 7, 391-402.
7. Redies C. and Takeichi M. (1996) Cadherins in the developing central nervous system: an adhesive code for segmental and functional subdivisions. Dev. Biol. 180, 413-423.
8. Sato M., Mori Y., Sakurada A., Fukushige S., Ichikawa Y., Tsuchiya E., Saito Y., Nukiwa T., Fujimura S., and Horii A. (1998a) Identification of a 910 kb region of common allelic loss in chromosome bands 16q24.1-q24.2 in human lung cancer. Genes Chromosom. Cancer 22, 1-8.
9. Sato M., Mori Y., Sakurada A., Fujimura S., and Horii A. (1998b) The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum. Genet. 103, 96-101.
10. Takeuchi T., Chen B.-K., Qiu Y., Sonobe H., and Ohtsuki Y. (1997) Molecular cloning and expression of a novel human cDNA containing CAG repeats. Gene 204, 71-77.
11. Takeuchi T., Misaki A., Chen B.-K., and Ohtsuki Y. (1999) H-cadherin expression in breast cancer. Histopathology 35, 87-88.
12. Tanihara H., Sano K., Heimark R. L., St. John T., and Suzuki S. (1994) Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin. Cell Adhes. Commun. 2, 15-26.
13. Tkachuk V. A., Bochkov V. N., Philippova M. P., Stambolsky D. V., Kuzmenko E. S., Sidorova M. V., Molokoedov A. S., Spirov V. G., and Resink T. J. (1998) Identification of an atypical lipoprotein-binding protein from human aortic smooth muscle as T-cadherin. FEBS Lett. 421, 208-212.
14. Towbin H., Staehelin T., and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
15. Tsuda H., Zhang W., Shimosato Y., Yokota J., Terada M., Sugimura T., Miyamura T., and Hirohashi S. (1990) Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA 87, 6791-6794.
16. Tsuda H., Callen D. F., Fukutomi T., Nakamura Y., and Hirohashi S. (1994) Allelic loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread. Cancer Res. 54, 513-517.