Family-based genome-wide association scan of attention-deficit/ hyperactivity disorder

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 49, Issue 9, 2010, Pages

  Mick, Eric ^a   Todorov, Alexandre ^b   Smalley, Susan ^c   Hu, Xiaolan ^d   Loo, Sandra ^c   Todd, Richard D ^b   Biederman, Joseph ^a   Byrne, Deirdre ^a   Dechairo, Bryan ^d   Guiney, Allan ^a   McCracken, James ^c   McGough, James ^c   Nelson, Stanley F ^c   Reiersen, Angela M ^b   Wilens, Timothy E ^a   Wozniak, Janet ^a   Neale, Benjamin M ^a   Faraone, Stephen V ^e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d PFIZER INC   (United States)

^e SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

ADHD; genome wide association study; SLC9A9

Indexed keywords

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FAMILY; FEMALE; FOLLOW UP; GENE; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITY CONTROL; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 77955668718     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1016/j.jaac.2010.02.014     Document Type: Article

References (29)

1. E. Mick, and S.V. Faraone Genetics of attention deficit hyperactivity disorder Child Adolesc Psychiatr Clin North Am 17 2008 261 284
2. K. Zhou, A. Dempfle, and M. Arcos-Burgos Meta-analysis of genomewide linkage scans of attention deficit hyperactivity disorder Am J Med Genet B Neuropsychiatr Genet 147B 2008 1392 1398
3. K. Brookes, X. Xu, and W. Chen The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes Mol Psychiatry 11 2006 934 953
4. K.P. Lesch, N. Timmesfeld, and T.J. Renner Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies J Neural Transm 115 2008 1573 1585
5. B.M. Neale, J. Lasky-Su, and R. Anney Genome-wide association scan of attention deficit hyperactivity disorder Am J Med Genet B Neuropsychiatr Genet 147B 2008 1337 1344
6. J. Lasky-Su, B.M. Neale, and B. Franke Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations Am J Med Genet B Neuropsychiatr Genet 147B 2008 1345 1354
7. R.D. Todd, N. Sitdhiraksa, and W. Reich Discrimination of DSM-IV and latent class attention-deficit/hyperactivity disorder subtypes by educational and cognitive performance in a population-based sample of child and adolescent twins J Am Acad Child Adolesc Psychiatry 41 2002 820 828
8. R.J. Neuman, N. Sitdhiraksa, and W. Reich Estimation of prevalence of DSM-IV and latent class-defined ADHD subtypes in a population-based sample of child and adolescent twins Twin Res Hum Genet 8 2005 392 401
9. R.D. Todd, C.A. Joyner, A.C. Heath, R.J. Neuman, and W. Reich Reliability and stability of a semistructured DSM-IV interview designed for family studies J Am Acad Child Adolesc Psychiatry 42 2003 1460 1468
10. S.L. Smalley, J.J. McGough, and M. Del'Homme Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder J Am Acad Child Adolesc Psychiatry 39 2000 1135 1143
11. D.J. Cutler, M.E. Zwick, and M.M. Carrasquillo High-throughput variation detection and genotyping using microarrays Genome Res 11 2001 1913 1925
12. D. Gordon, S.J. Finch, M. Nothnagel, and J. Ott Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms Hum Hered 54 2002 22 33
13. J.N. Hirschhorn, and M.J. Daly Genome-wide association studies for common diseases and complex traits Nat Rev Genet 6 2005 95 108
14. S. Purcell, B. Neale, and K. Todd-Brown PLINK: a tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575
15. F. Dudbridge, and A. Gusnanto Estimation of significance thresholds for genomewide association scans Genet Epidemiol 32 2008 227 234
16. I. Pe'er, R. Yelensky, D. Altshuler, and M.J. Daly Estimation of the multiple testing burden for genomewide association studies of nearly all common variants Genet Epidemiol 32 2008 381 385
17. I.R. Gizer, C. Ficks, and I.D. Waldman Candidate gene studies of ADHD: a meta-analytic review Hum Genet 126 2009 51 90
18. M.G. de Silva, K. Elliott, and H.H. Dahl Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype J Med Genet 40 2003 733 740
19. J. Lasky-Su, R.J. Anney, and B.M. Neale Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder Am J Med Genet B Neuropsychiatr Genet 147B 2008 1355 1358
20. S.V. Faraone, R.H. Perlis, and A.E. Doyle Molecular genetics of attention deficit hyperactivity disorder Biol Psychiatry 57 2005 1313 1323
21. D. Levy, G.B. Ehret, and K. Rice Genome-wide association study of blood pressure and hypertension Nat Genet 41 2009 677 687
22. C. Newton-Cheh, T. Johnson, and V. Gateva Genome-wide association study identifies eight loci associated with blood pressure Nat Genet 41 2009 666 676
23. S.V. Faraone, J. Biederman, and E. Mick The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies Psychol Med 36 2006 159 165
24. S.V. Faraone, J. Biederman, and M.C. Monuteaux Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder Genet Epidemiol 18 2000 1 16
25. E.J. Sonuga-Barke, J. Lasky-Su, and B.M. Neale Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan Am J Med Genet B Neuropsychiatr Genet 147B 2008 1359 1368
26. R.J. Anney, J. Lasky-Su, and C. O'Dushlaine Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study Am J Med Genet B Neuropsychiatr Genet 147B 2008 1369 1378
27. Elia J, Gai X, Xie HM, et al. Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes [published online ahead of print June 23, 2009]. Mol Psychiatry. doi: 10.1038/mp.2009.57.
28. B.M. Neale, and S. Purcell The positives, protocols, and perils of genome-wide association Am J Med Genet B Neuropsychiatr Genet 147B 2008 1288 1294
29. A framework for interpreting genome-wide association studies of psychiatric disorders Mol Psychiatry 14 2009 10 17