메뉴 건너뛰기




Volumn 98, Issue 2, 2015, Pages 200-207

Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis

Author keywords

Burkitt lymphoma; Decitabine; DNMT1; DNMT3A; DNMT3B; MiR 29 family

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MICRORNA 29; MICRORNA 29A; MICRORNA 29B; MICRORNA 29C; UNCLASSIFIED DRUG; 5-AZA-2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE; AZACITIDINE; CYTIDINE TRIPHOSPHATE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; MESSENGER RNA; MICRORNA; MIRN29 MICRORNA, HUMAN;

EID: 84924662962     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2015.03.006     Document Type: Article
Times cited : (64)

References (70)
  • 1
    • 84888134905 scopus 로고    scopus 로고
    • DNMT3B7 expression related to MENT expression and its promoter methylation in human lymphomas
    • Alkebsi L., et al. DNMT3B7 expression related to MENT expression and its promoter methylation in human lymphomas. Leuk. Res. 2013, 37:1662-1667.
    • (2013) Leuk. Res. , vol.37 , pp. 1662-1667
    • Alkebsi, L.1
  • 2
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T.H. The DNA methyltransferases of mammals. Hum. Mol. Genet. 2000, 9:2395-2402.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 3
    • 0037355506 scopus 로고    scopus 로고
    • Unanswered questions about the role of promoter methylation in carcinogenesis
    • Bestor T.H. Unanswered questions about the role of promoter methylation in carcinogenesis. Ann. N. Y. Acad. Sci. 2003, 983:22-27.
    • (2003) Ann. N. Y. Acad. Sci. , vol.983 , pp. 22-27
    • Bestor, T.H.1
  • 4
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Broske A.M., et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat. Genet. 2009, 41:1207-1215.
    • (2009) Nat. Genet. , vol.41 , pp. 1207-1215
    • Broske, A.M.1
  • 5
    • 79959383011 scopus 로고    scopus 로고
    • Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway
    • Bueno M.J., et al. Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway. Blood 2011, 117:6255-6266.
    • (2011) Blood , vol.117 , pp. 6255-6266
    • Bueno, M.J.1
  • 6
    • 79952694643 scopus 로고    scopus 로고
    • Myc: maestro of microRNAs
    • Bui T.V., Mendell J.T. Myc: maestro of microRNAs. Genes Cancer 2010, 1:568-575.
    • (2010) Genes Cancer , vol.1 , pp. 568-575
    • Bui, T.V.1    Mendell, J.T.2
  • 7
    • 37549008310 scopus 로고    scopus 로고
    • Widespread microRNA repression by Myc contributes to tumorigenesis
    • Chang T.C., et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat. Genet. 2008, 40:43-50.
    • (2008) Nat. Genet. , vol.40 , pp. 43-50
    • Chang, T.C.1
  • 8
    • 0037255729 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases in multistep hepatocarcinogenesis
    • Choi M.S., et al. Expression of DNA methyltransferases in multistep hepatocarcinogenesis. Hum. Pathol. 2003, 34:11-17.
    • (2003) Hum. Pathol. , vol.34 , pp. 11-17
    • Choi, M.S.1
  • 9
    • 84855718050 scopus 로고    scopus 로고
    • TET2 and DNMT3A mutations in human T-cell lymphoma
    • Couronne L., et al. TET2 and DNMT3A mutations in human T-cell lymphoma. N. Engl. J. Med. 2012, 366:95-96.
    • (2012) N. Engl. J. Med. , vol.366 , pp. 95-96
    • Couronne, L.1
  • 11
    • 0000538165 scopus 로고
    • Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
    • Dalla-Favera R., et al. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl. Acad. Sci. U. S. A. 1982, 79:7824-7827.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 7824-7827
    • Dalla-Favera, R.1
  • 12
    • 84859171807 scopus 로고    scopus 로고
    • MYC on the path to cancer
    • Dang C.V. MYC on the path to cancer. Cell 2012, 149:22-35.
    • (2012) Cell , vol.149 , pp. 22-35
    • Dang, C.V.1
  • 13
    • 33645279862 scopus 로고    scopus 로고
    • Molecular diagnosis of Burkitt's lymphoma
    • Dave S.S., et al. Molecular diagnosis of Burkitt's lymphoma. N. Engl. J. Med. 2006, 354:2431-2442.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2431-2442
    • Dave, S.S.1
  • 14
    • 84873519286 scopus 로고    scopus 로고
    • Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity
    • De S., et al. Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity. PLoS Genet. 2013, 9:e1003137.
    • (2013) PLoS Genet. , vol.9 , pp. e1003137
    • De, S.1
  • 15
    • 79959990071 scopus 로고    scopus 로고
    • Regulation of mammalian DNA methyltransferases: a route to new mechanisms
    • Denis H., et al. Regulation of mammalian DNA methyltransferases: a route to new mechanisms. EMBO Rep. 2011, 12:647-656.
    • (2011) EMBO Rep. , vol.12 , pp. 647-656
    • Denis, H.1
  • 16
    • 84865790633 scopus 로고    scopus 로고
    • The role of miRNAs in the pathogenesis and diagnosis of B-cell lymphomas
    • Di Lisio L., et al. The role of miRNAs in the pathogenesis and diagnosis of B-cell lymphomas. Blood 2012, 120:1782-1790.
    • (2012) Blood , vol.120 , pp. 1782-1790
    • Di Lisio, L.1
  • 17
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • Fabbri M., et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:15805-15810.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 15805-15810
    • Fabbri, M.1
  • 18
    • 84856555311 scopus 로고    scopus 로고
    • A DNA methylation fingerprint of 1628 human samples
    • Fernandez A.F., et al. A DNA methylation fingerprint of 1628 human samples. Genome Res. 2012, 22:407-419.
    • (2012) Genome Res. , vol.22 , pp. 407-419
    • Fernandez, A.F.1
  • 19
    • 47149109822 scopus 로고    scopus 로고
    • MicroRNAs in normal and malignant hematopoiesis
    • Garzon R., Croce C.M. MicroRNAs in normal and malignant hematopoiesis. Curr. Opin. Hematol. 2008, 15:352-358.
    • (2008) Curr. Opin. Hematol. , vol.15 , pp. 352-358
    • Garzon, R.1    Croce, C.M.2
  • 20
    • 73949118737 scopus 로고    scopus 로고
    • MicroRNA 29b functions in acute myeloid leukemia
    • Garzon R., et al. MicroRNA 29b functions in acute myeloid leukemia. Blood 2009, 114:5331-5341.
    • (2009) Blood , vol.114 , pp. 5331-5341
    • Garzon, R.1
  • 21
    • 67650588646 scopus 로고    scopus 로고
    • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
    • Garzon R., et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009, 113:6411-6418.
    • (2009) Blood , vol.113 , pp. 6411-6418
    • Garzon, R.1
  • 22
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I., et al. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin. Cancer Res. 2003, 9:4415-4422.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4415-4422
    • Girault, I.1
  • 23
    • 0034327890 scopus 로고    scopus 로고
    • Molecular biology of Burkitt's lymphoma
    • Hecht J.L., Aster J.C. Molecular biology of Burkitt's lymphoma. J. Clin. Oncol. 2000, 18:3707-3721.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3707-3721
    • Hecht, J.L.1    Aster, J.C.2
  • 24
    • 9144256125 scopus 로고    scopus 로고
    • The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
    • Hermann A., et al. The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J. Biol. Chem. 2004, 279:48350-48359.
    • (2004) J. Biol. Chem. , vol.279 , pp. 48350-48359
    • Hermann, A.1
  • 25
    • 58149382688 scopus 로고    scopus 로고
    • Classification of lymphoid neoplasms: the microscope as a tool for disease discovery
    • Jaffe E.S., et al. Classification of lymphoid neoplasms: the microscope as a tool for disease discovery. Blood 2008, 112:4384-4399.
    • (2008) Blood , vol.112 , pp. 4384-4399
    • Jaffe, E.S.1
  • 26
    • 84883258954 scopus 로고    scopus 로고
    • MicroRNAs in lymphoma, from diagnosis to targeted therapy
    • Jardin F., Figeac M. MicroRNAs in lymphoma, from diagnosis to targeted therapy. Curr. Opin. Oncol. 2013, 25:480-486.
    • (2013) Curr. Opin. Oncol. , vol.25 , pp. 480-486
    • Jardin, F.1    Figeac, M.2
  • 27
    • 77956902023 scopus 로고    scopus 로고
    • Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    • Ji H., et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010, 467:338-342.
    • (2010) Nature , vol.467 , pp. 338-342
    • Ji, H.1
  • 28
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • Jones P.A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 2012, 13:484-492.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 29
    • 78751470921 scopus 로고    scopus 로고
    • Structure and function of mammalian DNA methyltransferases
    • Jurkowska R.Z., et al. Structure and function of mammalian DNA methyltransferases. Chembiochem 2011, 12:206-222.
    • (2011) Chembiochem , vol.12 , pp. 206-222
    • Jurkowska, R.Z.1
  • 30
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
    • Kasinski A.L., Slack F.J. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11:849-864.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 31
    • 33747891190 scopus 로고    scopus 로고
    • Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer
    • Kim H., et al. Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer. Cancer 2006, 107:1042-1049.
    • (2006) Cancer , vol.107 , pp. 1042-1049
    • Kim, H.1
  • 32
    • 79955060261 scopus 로고    scopus 로고
    • Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells
    • Kinney S.R., Pradhan S. Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells. Prog. Mol. Biol. Transl. Sci. 2011, 101:311-333.
    • (2011) Prog. Mol. Biol. Transl. Sci. , vol.101 , pp. 311-333
    • Kinney, S.R.1    Pradhan, S.2
  • 33
    • 0043130362 scopus 로고    scopus 로고
    • DNA sequence profile of TP53 gene mutations in childhood B-cell non-Hodgkin's lymphomas: prognostic implications
    • Klumb C.E., et al. DNA sequence profile of TP53 gene mutations in childhood B-cell non-Hodgkin's lymphomas: prognostic implications. Eur. J. Haematol. 2003, 71:81-90.
    • (2003) Eur. J. Haematol. , vol.71 , pp. 81-90
    • Klumb, C.E.1
  • 34
    • 0344825121 scopus 로고    scopus 로고
    • Geographic variation in Epstein-Barr virus-associated Burkitt's lymphoma in children from Brazil
    • Klumb C.E., et al. Geographic variation in Epstein-Barr virus-associated Burkitt's lymphoma in children from Brazil. Int. J. Cancer 2004, 108:66-70.
    • (2004) Int. J. Cancer , vol.108 , pp. 66-70
    • Klumb, C.E.1
  • 35
    • 3543147868 scopus 로고    scopus 로고
    • Treatment of children with B-cell non-Hodgkin's lymphoma in developing countries: the experience of a single center in Brazil
    • Klumb C.E., et al. Treatment of children with B-cell non-Hodgkin's lymphoma in developing countries: the experience of a single center in Brazil. J. Pediatr. Hematol. Oncol. 2004, 26:462-468.
    • (2004) J. Pediatr. Hematol. Oncol. , vol.26 , pp. 462-468
    • Klumb, C.E.1
  • 36
    • 84890450749 scopus 로고    scopus 로고
    • DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation
    • Lai A.Y., et al. DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation. Genome Res. 2013, 23:2030-2041.
    • (2013) Genome Res. , vol.23 , pp. 2030-2041
    • Lai, A.Y.1
  • 37
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley T.J., et al. DNMT3A mutations in acute myeloid leukemia. N. Engl. J. Med. 2010, 363:2424-2433.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 2424-2433
    • Ley, T.J.1
  • 38
    • 84875304496 scopus 로고    scopus 로고
    • DNA methyltransferases in hematologic malignancies
    • Li K.K., et al. DNA methyltransferases in hematologic malignancies. Semin. Hematol. 2013, 50:48-60.
    • (2013) Semin. Hematol. , vol.50 , pp. 48-60
    • Li, K.K.1
  • 39
    • 84867021989 scopus 로고    scopus 로고
    • Transcriptional amplification in tumor cells with elevated c-Myc
    • Lin C.Y., et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012, 151:56-67.
    • (2012) Cell , vol.151 , pp. 56-67
    • Lin, C.Y.1
  • 40
    • 0036392058 scopus 로고    scopus 로고
    • Role of genetic and epigenetic changes in Burkitt lymphoma
    • Lindstrom M.S., Wiman K.G. Role of genetic and epigenetic changes in Burkitt lymphoma. Semin. Cancer Biol. 2002, 12:381-387.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 381-387
    • Lindstrom, M.S.1    Wiman, K.G.2
  • 41
    • 0035283201 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    • Mizuno S., et al. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 2001, 97:1172-1179.
    • (2001) Blood , vol.97 , pp. 1172-1179
    • Mizuno, S.1
  • 42
    • 80051544985 scopus 로고    scopus 로고
    • DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer
    • Mutze K., et al. DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. Eur. J. Cancer 2011, 47:1817-1825.
    • (2011) Eur. J. Cancer , vol.47 , pp. 1817-1825
    • Mutze, K.1
  • 43
    • 79952421239 scopus 로고    scopus 로고
    • Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma
    • Nguyen T., et al. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics 2011, 6:388-394.
    • (2011) Epigenetics , vol.6 , pp. 388-394
    • Nguyen, T.1
  • 44
    • 66649097032 scopus 로고    scopus 로고
    • DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer
    • Nosho K., et al. DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clin. Cancer Res. 2009, 15:3663-3671.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3663-3671
    • Nosho, K.1
  • 45
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M., et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1
  • 46
    • 34547935029 scopus 로고    scopus 로고
    • Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins
    • Ostler K.R., et al. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene 2007, 26:5553-5563.
    • (2007) Oncogene , vol.26 , pp. 5553-5563
    • Ostler, K.R.1
  • 47
    • 37549068541 scopus 로고    scopus 로고
    • AID is required for germinal center-derived lymphomagenesis
    • Pasqualucci L., et al. AID is required for germinal center-derived lymphomagenesis. Nat. Genet. 2008, 40:108-112.
    • (2008) Nat. Genet. , vol.40 , pp. 108-112
    • Pasqualucci, L.1
  • 48
    • 23844472366 scopus 로고    scopus 로고
    • Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas
    • Peng D.F., et al. Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas. Cancer Sci. 2005, 96:403-408.
    • (2005) Cancer Sci. , vol.96 , pp. 403-408
    • Peng, D.F.1
  • 49
    • 84886924910 scopus 로고    scopus 로고
    • Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas
    • Peters S.L., et al. Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. Mol. Cell. Biol. 2013, 33:4321-4333.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 4321-4333
    • Peters, S.L.1
  • 50
    • 84899917808 scopus 로고    scopus 로고
    • Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis
    • Peters S.L., et al. Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis. Leukemia 2014, 28:1138-1142.
    • (2014) Leukemia , vol.28 , pp. 1138-1142
    • Peters, S.L.1
  • 52
    • 84924679211 scopus 로고    scopus 로고
    • Quantitative analysis of CDKN2A methylation, mRNA, and p16 protein expression in children and adolescents with Burkitt lymphoma: biological and clinical implications
    • Robaina M.C., et al. Quantitative analysis of CDKN2A methylation, mRNA, and p16 protein expression in children and adolescents with Burkitt lymphoma: biological and clinical implications. Leuk. Res. 2014.
    • (2014) Leuk. Res.
    • Robaina, M.C.1
  • 53
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson K.D., et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res. 1999, 27:2291-2298.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 2291-2298
    • Robertson, K.D.1
  • 54
    • 77952730045 scopus 로고    scopus 로고
    • MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma
    • Robertus J.L., et al. MiRNA profiling in B non-Hodgkin lymphoma: a MYC-related miRNA profile characterizes Burkitt lymphoma. Br. J. Haematol. 2010, 149:896-899.
    • (2010) Br. J. Haematol. , vol.149 , pp. 896-899
    • Robertus, J.L.1
  • 55
    • 39649104991 scopus 로고    scopus 로고
    • DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
    • Roll J.D., et al. DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol. Cancer 2008, 7:15.
    • (2008) Mol. Cancer , vol.7 , pp. 15
    • Roll, J.D.1
  • 56
    • 84865114403 scopus 로고    scopus 로고
    • Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis
    • Sander S., et al. Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis. Cancer Cell 2012, 22:167-179.
    • (2012) Cancer Cell , vol.22 , pp. 167-179
    • Sander, S.1
  • 57
    • 84867051939 scopus 로고    scopus 로고
    • Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    • Schmitz R., et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012, 490:116-120.
    • (2012) Nature , vol.490 , pp. 116-120
    • Schmitz, R.1
  • 58
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer A.L., et al. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 2000, 13:199-212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1
  • 59
    • 77955038710 scopus 로고    scopus 로고
    • DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis
    • Shah M.Y., et al. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res. 2010, 70:5840-5850.
    • (2010) Cancer Res. , vol.70 , pp. 5840-5850
    • Shah, M.Y.1
  • 60
    • 80053376487 scopus 로고    scopus 로고
    • DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation
    • Shaknovich R., et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood 2011, 118:3559-3569.
    • (2011) Blood , vol.118 , pp. 3559-3569
    • Shaknovich, R.1
  • 61
    • 84856990498 scopus 로고    scopus 로고
    • Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation
    • Song J., et al. Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science 2012, 335:709-712.
    • (2012) Science , vol.335 , pp. 709-712
    • Song, J.1
  • 62
    • 84904647822 scopus 로고    scopus 로고
    • DNA methyltransferases: a novel target for prevention and therapy
    • Subramaniam D., et al. DNA methyltransferases: a novel target for prevention and therapy. Front. Oncol. 2014, 4:80.
    • (2014) Front. Oncol. , vol.4 , pp. 80
    • Subramaniam, D.1
  • 63
    • 2342575723 scopus 로고    scopus 로고
    • RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells
    • Suzuki M., et al. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells. Cancer Res. 2004, 64:3137-3143.
    • (2004) Cancer Res. , vol.64 , pp. 3137-3143
    • Suzuki, M.1
  • 64
    • 84880742480 scopus 로고    scopus 로고
    • Role of microRNA in the pathogenesis of malignant lymphoma
    • Tagawa H., et al. Role of microRNA in the pathogenesis of malignant lymphoma. Cancer Sci. 2013, 104:801-809.
    • (2013) Cancer Sci. , vol.104 , pp. 801-809
    • Tagawa, H.1
  • 65
    • 0001292985 scopus 로고
    • Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
    • Taub R., et al. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl. Acad. Sci. U. S. A. 1982, 79:7837-7841.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 7837-7841
    • Taub, R.1
  • 66
    • 84893874694 scopus 로고    scopus 로고
    • AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine
    • Tsai C.T., et al. AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine. Oncotarget 2014, 5:211-223.
    • (2014) Oncotarget , vol.5 , pp. 211-223
    • Tsai, C.T.1
  • 67
    • 72449174826 scopus 로고    scopus 로고
    • The role of microRNAs in normal and malignant hematopoiesis
    • Vasilatou D., et al. The role of microRNAs in normal and malignant hematopoiesis. Eur. J. Haematol. 2010, 84:1-16.
    • (2010) Eur. J. Haematol. , vol.84 , pp. 1-16
    • Vasilatou, D.1
  • 68
    • 84875381512 scopus 로고    scopus 로고
    • The role of miRNA-29 family in cancer
    • Wang Y., et al. The role of miRNA-29 family in cancer. Eur. J. Cell Biol. 2013, 92:123-128.
    • (2013) Eur. J. Cell Biol. , vol.92 , pp. 123-128
    • Wang, Y.1
  • 69
    • 77950602604 scopus 로고    scopus 로고
    • Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    • Xiong Y., et al. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 2010, 51:836-845.
    • (2010) Hepatology , vol.51 , pp. 836-845
    • Xiong, Y.1
  • 70
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N., et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006, 9:189-198.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.