RNA Interference-Mediated Knockdown of DNA Methyltransferase 1 Leads to Promoter Demethylation and Gene Re-Expression in Human Lung and Breast Cancer Cells

Cancer Research

Volumn 64, Issue 9, 2004, Pages 3137-3143

  Suzuki, Makoto ^a,c   Sunaga, Noriaki ^a   Shames, David S ^a   Toyooka, Shinichi ^a   Gazdar, Adi F ^a,b   Minna, John D ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; DNA METHYLTRANSFERASE 1; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL; CANCER GENETICS; CELL STRAIN; CELL STRAIN HCC 1954; CELL STRAIN NCI H1299; CONTROLLED STUDY; DEMETHYLATION; DOWN REGULATION; EPIGENETICS; EVIDENCE BASED MEDICINE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; KNOCKOUT GENE; LUNG CANCER; LUNG CARCINOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA INTERFERENCE; RNA SEQUENCE; TUMOR CELL; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LUNG NEOPLASMS; PROMOTER REGIONS (GENETICS); RNA INTERFERENCE; RNA, MESSENGER; TRANSFECTION;

EID: 2342575723     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3046     Document Type: Article

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