Iodoacetic acid activates Nrf2-mediated antioxidant response in Vitro and in Vivo

Environmental Science and Technology

Volumn 48, Issue 22, 2014, Pages 13478-13488

  Wang, Shu ^a   Zheng, Weiwei ^a   Liu, Xiaolin ^a   Xue, Peng ^a   Jiang, Songhui ^a   Lu, Daru ^b   Zhang, Qiang ^d   He, Gensheng ^a   Pi, Jingbo ^c   Andersen, Melvin E ^d   Tan, Hui ^a   Qu, Weidong ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

^d HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DISINFECTION; GENE EXPRESSION; POTABLE WATER; TOXICITY;

ANTI-OXIDANT RESPONSE; ANTIOXIDANT RESPONSE ELEMENTS; CONCENTRATION-DEPENDENT MANNERS; DRINKING WATER DISINFECTION; ENHANCED SENSITIVITY; IODOACETIC ACID; PROTEIN EXPRESSIONS; RELATED FACTORS;

ANTIOXIDANTS;

ANTIOXIDANT; CURCUMIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE; IODOACETIC ACID; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LUCIFERASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; ENZYME INHIBITOR; NFE2L2 PROTEIN, HUMAN;

ACETIC ACID; ANTIOXIDANT; CELL ORGANELLE; GENE EXPRESSION; GENOTOXICITY; OXIDATION; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CLINICAL EVALUATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENE EXPRESSION; GENOTOXICITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LUCIFERASE ASSAY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SENSITIVITY ANALYSIS; TOXICITY TESTING; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; OXIDATION REDUCTION REACTION; TIME;

ANIMALIA; RATTUS;

ANIMALS; ANTIOXIDANTS; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUTATHIONE; HEP G2 CELLS; HUMANS; IODOACETIC ACID; MALE; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; TIME FACTORS;

EID: 84924587788     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es502855x     Document Type: Article

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