Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts

Environmental Science and Technology

Volumn 47, Issue 21, 2013, Pages 12514-12523

  Pals, Justin ^a   Attene Ramos, Matias S ^b   Xia, Menghang ^b   Wagner, Elizabeth D ^a   Plewa, Michael J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT RESPONSE ELEMENTS; DRINKING WATER DISINFECTION; FUNCTIONAL ASSOCIATIONS; INTESTINAL EPITHELIAL CELLS; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATES; REACTIVE OXYGEN SPECIES; THIOREDOXIN REDUCTASE 1; TRANSCRIPTOME PROFILES;

ANTIOXIDANTS; CELL CULTURE; DISINFECTION; OXIDATIVE STRESS; OXYGEN; TOXICITY; TRANSCRIPTION;

BYPRODUCTS;

ACETIC ACID; BROMOACETIC ACID; CHLOROACETIC ACID; DRINKING WATER; IODOACETIC ACID; MESSENGER RNA; MONOHALOACETIC ACID; PEROXIREDOXIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOREDOXIN REDUCTASE 1; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; BETA LACTAMASE;

ACETIC ACID; ANTIOXIDANT; CANCER; CELL ORGANELLE; DISINFECTION; DRINKING WATER; ENZYME ACTIVITY; GENOMICS; HEALTH RISK; METABOLISM; OXIDATION; OXYGEN; POLLUTION EXPOSURE; TOXICITY;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISINFECTION; GENOTOXICITY; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; OXIDATIVE STRESS; TOXICOGENETICS; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; METABOLISM; REPORTER GENE;

ACETATES; BETA-LACTAMASES; CELL LINE; DISINFECTION; DRINKING WATER; GENE EXPRESSION REGULATION; GENES, REPORTER; HEP G2 CELLS; HUMANS; IODOACETIC ACID; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TOXICOGENETICS;

EID: 84887966475     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es403171b     Document Type: Article

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