Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

Environmental Health Perspectives

Volumn 119, Issue 1, 2011, Pages 56-62

  Zhao, Rui ^a,b   Hou, Yongyong ^a,b   Xue, Peng ^a,b   Woods, Courtney G ^b   Fu, Jingqi ^a,b   Feng, Bo ^a   Guan, Dawei ^a   Sun, Guifan ^a   Chan, Jefferson Y ^c   Waalkes, Michael P ^d   Andersen, Melvin E ^b   Pi, Jingbo ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Apoptosis; Arsenic; Cytotoxicity; Keap1; Keratinocyte; Nrf1; Nrf2; Oxidative stress

Indexed keywords

ARSENIC TRIOXIDE; GAMMA GLUTAMATE CYSTEINE LIGASE CATALYTIC SUBUNIT; GAMMA GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LENTIVIRUS VECTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; CELL LEVEL; CELL NUCLEUS; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME REGULATION; GENE INDUCTION; GENE SILENCING; HUMAN; HUMAN CELL; KERATINOCYTE; MOLECULAR SIZE; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANTIOXIDANTS; ARSENIC; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; HUMANS; KERATINOCYTES; NF-E2-RELATED FACTOR 1; OXIDATIVE STRESS; PROTEIN ISOFORMS; RNA, MESSENGER;

EID: 78751560531     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002304     Document Type: Article

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