mESC-based in vitro differentiation models to study vascular response and functionality following genotoxic insults

Toxicological Sciences

Volumn 144, Issue 1, 2015, Pages 138-150

  Hennicke, Tatiana ^a   Nieweg, Katja ^a   Brockmann, Nicole ^a   Kassack, Matthias U ^a   Gottmann, Kurt ^a   Fritz, Gerhard ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Differentiation; DNA damage response; DNA repair; Ionizing radiation; Mouse embryonic stem cells; Vascular cells

Indexed keywords

CHECKPOINT KINASE 1; HISTONE H2AX; KRAB DOMAIN ASSOCIATED PROTEIN 1; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BIOLOGICAL MARKER; CELL CYCLE PROTEIN; H2AX PROTEIN, MOUSE; HISTONE; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; BLOOD VESSEL REACTIVITY; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; EXCISION REPAIR; GENE EXPRESSION; GENOTOXICITY; IN VITRO STUDY; IONIZING RADIATION; MISMATCH REPAIR; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; SMOOTH MUSCLE FIBER; UPREGULATION; ANGIOGENESIS; ANIMAL; CELL CYCLE; CELL LINE; ENDOTHELIAL PROGENITOR CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PLURIPOTENT STEM CELL; RADIATION RESPONSE; TIME; VASCULAR SMOOTH MUSCLE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BIOMARKERS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; EMBRYONIC STEM CELLS; ENDOTHELIAL PROGENITOR CELLS; GENE EXPRESSION REGULATION; HISTONES; MICE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PLURIPOTENT STEM CELLS; RNA, MESSENGER; TIME FACTORS;

EID: 84924457091     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu264     Document Type: Article

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