메뉴 건너뛰기




Volumn 34, Issue 3, 2012, Pages 218-225

Purinergic signalling: Its unpopular beginning, its acceptance and its exciting future

Author keywords

ATP release and breakdown; Neurodegenerative diseases; P1; P2X; P2Y; Pain; Purinergic neuropathology; Purinoceptors

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; CALCITONIN GENE RELATED PEPTIDE; DOPAMINE; GLUTAMIC ACID; NEUROPEPTIDE Y; NITRIC OXIDE; NORADRENALIN; PURINERGIC P2 RECEPTOR; PURINERGIC P2X1 RECEPTOR; PURINERGIC P2X2 RECEPTOR; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X5 RECEPTOR; PURINERGIC P2X6 RECEPTOR; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC P2Y4 RECEPTOR; PURINERGIC P2Y6 RECEPTOR; PURINERGIC RECEPTOR; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 84857045446     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201100130     Document Type: Review
Times cited : (181)

References (112)
  • 1
    • 0001627970 scopus 로고
    • Inhibition of the smooth muscle of the taenia coli
    • Burnstock G, Campbell G, Bennett M, Holman ME. 1963. Inhibition of the smooth muscle of the taenia coli. Nature 200: 581- 2.
    • (1963) Nature , vol.200 , pp. 581-582
    • Burnstock, G.1    Campbell, G.2    Bennett, M.3    Holman, M.E.4
  • 2
    • 62749138840 scopus 로고    scopus 로고
    • A moment of excitement. Living History Series. The discovery of non-adrenergic, non-cholinergic neurotransmission
    • Burnstock G. 2004. A moment of excitement. Living History Series. The discovery of non-adrenergic, non-cholinergic neurotransmission. Physiol News 56: 7- 9.
    • (2004) Physiol News , vol.56 , pp. 7-9
    • Burnstock, G.1
  • 3
    • 0000533976 scopus 로고
    • Innervation of the guinea-pig taenia coli: Are there intrinsic inhibitory nerves which are distinct from sympathetic nerves
    • Burnstock G, Campbell G, Bennett M, Holman ME. 1964. Innervation of the guinea-pig taenia coli: Are there intrinsic inhibitory nerves which are distinct from sympathetic nerves? Int J Neuropharmacol 3: 163- 6.
    • (1964) Int J Neuropharmacol , vol.3 , pp. 163-166
    • Burnstock, G.1    Campbell, G.2    Bennett, M.3    Holman, M.E.4
  • 4
    • 0013881908 scopus 로고
    • The inhibitory innervation of the taenia of the guinea-pig caecum
    • Burnstock G, Campbell G, Rand MJ. 1966. The inhibitory innervation of the taenia of the guinea-pig caecum. J Physiol 182: 504- 26.
    • (1966) J Physiol , vol.182 , pp. 504-526
    • Burnstock, G.1    Campbell, G.2    Rand, M.J.3
  • 5
    • 84940815279 scopus 로고
    • The physiological activity of adenine compounds with special reference to their action upon the mammalian heart
    • Drury AN, Szent-Györgyi A. 1929. The physiological activity of adenine compounds with special reference to their action upon the mammalian heart. J Physiol (Lond) 68: 213- 37.
    • (1929) J Physiol (Lond) , vol.68 , pp. 213-237
    • Drury, A.N.1    Szent-Györgyi, A.2
  • 6
    • 0004874748 scopus 로고
    • The stimulating action of phosphate compounds on the perfused superior cervical ganglion of the cat
    • Feldberg W, Hebb C. 1948. The stimulating action of phosphate compounds on the perfused superior cervical ganglion of the cat. J Physiol 107: 210- 21.
    • (1948) J Physiol , vol.107 , pp. 210-221
    • Feldberg, W.1    Hebb, C.2
  • 7
    • 0011731358 scopus 로고
    • The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves
    • Holton P. 1959. The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves. J Physiol 145: 494- 504.
    • (1959) J Physiol , vol.145 , pp. 494-504
    • Holton, P.1
  • 8
    • 0014891847 scopus 로고
    • Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut
    • Burnstock G, Campbell G, Satchell D, Smythe A. 1970. Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut. Br J Pharmacol 40: 668- 88.
    • (1970) Br J Pharmacol , vol.40 , pp. 668-688
    • Burnstock, G.1    Campbell, G.2    Satchell, D.3    Smythe, A.4
  • 9
    • 0015393308 scopus 로고
    • Purinergic nerves
    • Burnstock G. 1972. Purinergic nerves. Pharmacol Rev 24: 509- 81.
    • (1972) Pharmacol Rev , vol.24 , pp. 509-581
    • Burnstock, G.1
  • 10
    • 0015237341 scopus 로고
    • 3H]Adenosine triphosphate: release during stimulation of enteric nerves
    • 3H]Adenosine triphosphate: release during stimulation of enteric nerves. Science 173: 337- 9.
    • (1971) Science , vol.173 , pp. 337-339
    • Su, C.1    Bevan, J.A.2    Burnstock, G.3
  • 11
    • 0017162094 scopus 로고
    • Do some nerve cells release more than one transmitter
    • Burnstock G. 1976. Do some nerve cells release more than one transmitter? Neuroscience 1: 239- 48.
    • (1976) Neuroscience , vol.1 , pp. 239-248
    • Burnstock, G.1
  • 12
    • 72849155337 scopus 로고
    • The transmission of excitation from autonomic nerve to smooth muscle
    • Burnstock G, Holman ME. 1961. The transmission of excitation from autonomic nerve to smooth muscle. J Physiol 155: 115- 33.
    • (1961) J Physiol , vol.155 , pp. 115-133
    • Burnstock, G.1    Holman, M.E.2
  • 13
    • 0020404352 scopus 로고
    • The use of the slowly degradable analog, α,β-methylene ATP, to produce desensitisation of the P2-purinoceptor: effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder
    • Kasakov L, Burnstock G. 1983. The use of the slowly degradable analog, α, β-methylene ATP, to produce desensitisation of the P2-purinoceptor: effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder. Eur J Pharmacol 86: 291- 4.
    • (1983) Eur J Pharmacol , vol.86 , pp. 291-294
    • Kasakov, L.1    Burnstock, G.2
  • 14
    • 0021321004 scopus 로고
    • Inhibition of excitatory junction potentials in guinea-pig vas deferens by α,β-methylene-ATP: further evidence for ATP and noradrenaline as cotransmitters
    • Sneddon P, Burnstock G. 1984. Inhibition of excitatory junction potentials in guinea-pig vas deferens by α, β-methylene-ATP: further evidence for ATP and noradrenaline as cotransmitters. Eur J Pharmacol 100: 85- 90.
    • (1984) Eur J Pharmacol , vol.100 , pp. 85-90
    • Sneddon, P.1    Burnstock, G.2
  • 15
    • 34248576759 scopus 로고    scopus 로고
    • Physiology and pathophysiology of purinergic neurotransmission
    • Burnstock G. 2007. Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87: 659- 797.
    • (2007) Physiol Rev , vol.87 , pp. 659-797
    • Burnstock, G.1
  • 16
    • 0026771094 scopus 로고
    • ATP mediates fast synaptic transmission in mammalian neurons
    • Evans RJ, Derkach V, Surprenant A. 1992. ATP mediates fast synaptic transmission in mammalian neurons. Nature 357: 503- 5.
    • (1992) Nature , vol.357 , pp. 503-505
    • Evans, R.J.1    Derkach, V.2    Surprenant, A.3
  • 17
    • 0026650238 scopus 로고
    • ATP mediates excitatory synaptic transmission in mammalian neurones
    • Silinsky EM, Gerzanich V, Vanner SM. 1992. ATP mediates excitatory synaptic transmission in mammalian neurones. Br J Pharmacol 106: 762- 3.
    • (1992) Br J Pharmacol , vol.106 , pp. 762-763
    • Silinsky, E.M.1    Gerzanich, V.2    Vanner, S.M.3
  • 18
    • 0026648857 scopus 로고
    • ATP receptor-mediated synaptic currents in the central nervous system
    • Edwards FA, Gibb AJ, Colquhoun D. 1992. ATP receptor-mediated synaptic currents in the central nervous system. Nature 359: 144- 7.
    • (1992) Nature , vol.359 , pp. 144-147
    • Edwards, F.A.1    Gibb, A.J.2    Colquhoun, D.3
  • 19
    • 0000179693 scopus 로고
    • A basis for distinguishing two types of purinergic receptor.
    • Straub RW, Bolis L, eds. New York: Raven Press.
    • Burnstock G. 1978. A basis for distinguishing two types of purinergic receptor. In Straub RW, Bolis L, eds; Cell Membrane Receptors for Drugs and Hormones: A Multidisciplinary Approach. New York: Raven Press. p. 107- 18.
    • (1978) Cell Membrane Receptors for Drugs and Hormones: A Multidisciplinary Approach , pp. 107-118
    • Burnstock, G.1
  • 20
    • 0022178232 scopus 로고
    • Is there a basis for distinguishing two types of P2-purinoceptor
    • Burnstock G, Kennedy C. 1985. Is there a basis for distinguishing two types of P2-purinoceptor? Gen Pharmacol 16: 433- 40.
    • (1985) Gen Pharmacol , vol.16 , pp. 433-440
    • Burnstock, G.1    Kennedy, C.2
  • 21
    • 0027312496 scopus 로고
    • Expression cloning of an ATP receptor from mouse neuroblastoma cells
    • Lustig KD, Shiau AK, Brake AJ, Julius D. 1993. Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci USA 90: 5113- 7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5113-5117
    • Lustig, K.D.1    Shiau, A.K.2    Brake, A.J.3    Julius, D.4
  • 22
    • 0027310852 scopus 로고
    • Cloning and functional expression of a brain G-protein-coupled ATP receptor
    • Webb TE, Simon J, Krishek BJ, Bateson AN, et al. 1993. Cloning and functional expression of a brain G-protein-coupled ATP receptor. FEBS Lett 324: 219- 25.
    • (1993) FEBS Lett , vol.324 , pp. 219-225
    • Webb, T.E.1    Simon, J.2    Krishek, B.J.3    Bateson, A.N.4
  • 23
    • 0028025001 scopus 로고
    • New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
    • Brake AJ, Wagenbach MJ, Julius D. 1994. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371: 519- 23.
    • (1994) Nature , vol.371 , pp. 519-523
    • Brake, A.J.1    Wagenbach, M.J.2    Julius, D.3
  • 24
    • 0028030797 scopus 로고
    • A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP
    • Valera S, Hussy N, Evans RJ, Adani N, et al. 1994. A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 371: 516- 9.
    • (1994) Nature , vol.371 , pp. 516-519
    • Valera, S.1    Hussy, N.2    Evans, R.J.3    Adani, N.4
  • 26
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G. 1998. Receptors for purines and pyrimidines. Pharmacol Rev 50: 413- 92.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 27
    • 34250719722 scopus 로고    scopus 로고
    • Purine and pyrimidine receptors
    • Burnstock G. 2007. Purine and pyrimidine receptors. Cell Mol Life Sci 64: 1471- 83.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1471-1483
    • Burnstock, G.1
  • 28
    • 0032089620 scopus 로고    scopus 로고
    • 3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels
    • 3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. EMBO J 17: 3016- 28.
    • (1998) EMBO J , vol.17 , pp. 3016-3028
    • Nicke, A.1    Baumert, H.G.2    Rettinger, J.3    Eichele, A.4
  • 30
    • 9144269934 scopus 로고    scopus 로고
    • Cellular distribution and functions of P2 receptor subtypes in different systems
    • Burnstock G, Knight GE. 2004. Cellular distribution and functions of P2 receptor subtypes in different systems. Int Rev Cytol 240: 31- 304.
    • (2004) Int Rev Cytol , vol.240 , pp. 31-304
    • Burnstock, G.1    Knight, G.E.2
  • 31
    • 53049107855 scopus 로고    scopus 로고
    • Purinergic systems in microglia
    • Inoue K. 2008. Purinergic systems in microglia. Cell Mol Life Sci 65: 3074- 80.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3074-3080
    • Inoue, K.1
  • 33
    • 77954308978 scopus 로고    scopus 로고
    • P2Y nucleotide receptors: promise of therapeutic applications
    • Jacobson KA, Boeynaems JM. 2010. P2Y nucleotide receptors: promise of therapeutic applications. Drug Discov Today 15: 570- 8.
    • (2010) Drug Discov Today , vol.15 , pp. 570-578
    • Jacobson, K.A.1    Boeynaems, J.M.2
  • 34
    • 77951590103 scopus 로고    scopus 로고
    • P2X purinergic receptor ligands: recently patented compounds
    • Gunosewoyo H, Kassiou M. 2010. P2X purinergic receptor ligands: recently patented compounds. Expert Opin Ther Pat 20: 625- 46.
    • (2010) Expert Opin Ther Pat , vol.20 , pp. 625-646
    • Gunosewoyo, H.1    Kassiou, M.2
  • 35
    • 77954895183 scopus 로고    scopus 로고
    • Progress towards novel adenosine receptor therapeutics gleaned from the recent patent literature
    • Press NJ, Fozard JR. 2010. Progress towards novel adenosine receptor therapeutics gleaned from the recent patent literature. Expert Opin Ther Pat 20: 987- 1005.
    • (2010) Expert Opin Ther Pat , vol.20 , pp. 987-1005
    • Press, N.J.1    Fozard, J.R.2
  • 36
    • 0035815630 scopus 로고    scopus 로고
    • A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor
    • Gu BJ, Zhang W, Worthington RA, Sluyter R, et al. 2001. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J Biol Chem 276: 11135- 42.
    • (2001) J Biol Chem , vol.276 , pp. 11135-11142
    • Gu, B.J.1    Zhang, W.2    Worthington, R.A.3    Sluyter, R.4
  • 37
    • 79953157461 scopus 로고    scopus 로고
    • 7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms
    • 7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms. J Biol Chem 286: 8176- 87.
    • (2011) J Biol Chem , vol.286 , pp. 8176-8187
    • Bradley, H.J.1    Baldwin, J.M.2    Goli, G.R.3    Johnson, B.4
  • 38
    • 79955957628 scopus 로고    scopus 로고
    • P2X receptors in health and disease.
    • Jacobson KA, Linden A, eds. Burlington: Academic Press.
    • Burnstock G, Kennedy C. 2011. P2X receptors in health and disease. In Jacobson KA, Linden A, eds; Purine and Pyrimidine Receptor Pharmacology. Burlington: Academic Press. p. 333- 72.
    • (2011) Purine and Pyrimidine Receptor Pharmacology , pp. 333-372
    • Burnstock, G.1    Kennedy, C.2
  • 39
    • 79960543099 scopus 로고    scopus 로고
    • Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots
    • Jiang S, Liu A, Duan H, Soo J, et al. 2011. Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots. Adv Funct Mater 21: 2776- 80.
    • (2011) Adv Funct Mater , vol.21 , pp. 2776-2780
    • Jiang, S.1    Liu, A.2    Duan, H.3    Soo, J.4
  • 40
    • 61849128446 scopus 로고    scopus 로고
    • Evolutionary origins of the purinergic signalling system
    • Burnstock G, Verkhratsky A. 2009. Evolutionary origins of the purinergic signalling system. Acta Physiol 195: 415- 47.
    • (2009) Acta Physiol , vol.195 , pp. 415-447
    • Burnstock, G.1    Verkhratsky, A.2
  • 41
    • 68349152690 scopus 로고    scopus 로고
    • An evolutionary history of P2X receptors
    • Fountain SJ, Burnstock G. 2009. An evolutionary history of P2X receptors. Purinergic Signal 5: 269- 72.
    • (2009) Purinergic Signal , vol.5 , pp. 269-272
    • Fountain, S.J.1    Burnstock, G.2
  • 42
    • 67049119566 scopus 로고    scopus 로고
    • Concept of sustained ordering and an ATP-related mechanism of life's origin
    • Galimov EM. 2009. Concept of sustained ordering and an ATP-related mechanism of life's origin. Int J Mol Sci 10: 2019- 30.
    • (2009) Int J Mol Sci , vol.10 , pp. 2019-2030
    • Galimov, E.M.1
  • 43
    • 80053294953 scopus 로고    scopus 로고
    • Evolution of neuronal signalling: transmitters and receptors
    • Hoyle CH. 2011. Evolution of neuronal signalling: transmitters and receptors. Auton Neurosci 165: 28- 53.
    • (2011) Auton Neurosci , vol.165 , pp. 28-53
    • Hoyle, C.H.1
  • 44
    • 4744370354 scopus 로고    scopus 로고
    • Functional characterization of a P2X receptor from Schistosoma mansoni
    • Agboh KC, Webb TE, Evans RJ, Ennion SJ. 2004. Functional characterization of a P2X receptor from Schistosoma mansoni. J Biol Chem 279: 41650- 7.
    • (2004) J Biol Chem , vol.279 , pp. 41650-41657
    • Agboh, K.C.1    Webb, T.E.2    Evans, R.J.3    Ennion, S.J.4
  • 45
    • 34447503350 scopus 로고    scopus 로고
    • An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum
    • Fountain SJ, Parkinson K, Young MT, Cao L, et al. 2007. An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum. Nature 448: 200- 3.
    • (2007) Nature , vol.448 , pp. 200-203
    • Fountain, S.J.1    Parkinson, K.2    Young, M.T.3    Cao, L.4
  • 46
    • 47249090581 scopus 로고    scopus 로고
    • Permeation properties of a P2X receptor in the green algae Ostreococcus tauri
    • Fountain SJ, Cao L, Young MT, North RA. 2008. Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. J Biol Chem 283: 15122- 6.
    • (2008) J Biol Chem , vol.283 , pp. 15122-15126
    • Fountain, S.J.1    Cao, L.2    Young, M.T.3    North, R.A.4
  • 48
    • 67651097634 scopus 로고    scopus 로고
    • Extracellular nucleotides: ancient signaling molecules
    • Clark G, Roux SJ. 2009. Extracellular nucleotides: ancient signaling molecules. Plant Sci 177: 239- 44.
    • (2009) Plant Sci , vol.177 , pp. 239-244
    • Clark, G.1    Roux, S.J.2
  • 49
    • 33751088273 scopus 로고    scopus 로고
    • Extracellular ATP in plants. Visualization, localization, and analysis of physiological significance in growth and signaling
    • Kim SY, Sivaguru M, Stacey G. 2006. Extracellular ATP in plants. Visualization, localization, and analysis of physiological significance in growth and signaling. Plant Physiol 142: 984- 92.
    • (2006) Plant Physiol , vol.142 , pp. 984-992
    • Kim, S.Y.1    Sivaguru, M.2    Stacey, G.3
  • 50
    • 79961199560 scopus 로고    scopus 로고
    • Extracellular nucleotides and apyrases regulate stomatal aperture in Arabidopsis
    • Clark G, Fraley D, Steinebrunner I, Cervantes A, et al. 2011. Extracellular nucleotides and apyrases regulate stomatal aperture in Arabidopsis. Plant Physiol 156: 1740- 53.
    • (2011) Plant Physiol , vol.156 , pp. 1740-1753
    • Clark, G.1    Fraley, D.2    Steinebrunner, I.3    Cervantes, A.4
  • 51
    • 70350485008 scopus 로고    scopus 로고
    • Extracellular ATP is a regulator of pathogen defence in plants
    • Chivasa S, Murphy AM, Hamilton JM, Lindsey K, et al. 2009. Extracellular ATP is a regulator of pathogen defence in plants. Plant J 60: 436- 48.
    • (2009) Plant J , vol.60 , pp. 436-448
    • Chivasa, S.1    Murphy, A.M.2    Hamilton, J.M.3    Lindsey, K.4
  • 52
    • 77349106961 scopus 로고    scopus 로고
    • Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression
    • Sreedharan S, Shaik JH, Olszewski PK, Levine AS, et al. 2010. Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression. BMC Genomics 11: 17.
    • (2010) BMC Genomics , vol.11 , pp. 17
    • Sreedharan, S.1    Shaik, J.H.2    Olszewski, P.K.3    Levine, A.S.4
  • 53
    • 0031770379 scopus 로고    scopus 로고
    • Purinergic signalling: pathophysiological roles
    • Abbracchio MP, Burnstock G. 1998. Purinergic signalling: pathophysiological roles. Jpn J Pharmacol 78: 113- 45.
    • (1998) Jpn J Pharmacol , vol.78 , pp. 113-145
    • Abbracchio, M.P.1    Burnstock, G.2
  • 54
    • 77951217576 scopus 로고    scopus 로고
    • Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death
    • Burnstock G, Verkhratsky A. 2010. Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death. Cell Death Dis 1: e9.
    • (2010) Cell Death Dis , vol.1
    • Burnstock, G.1    Verkhratsky, A.2
  • 55
    • 0036118418 scopus 로고    scopus 로고
    • Purinergic signalling and vascular cell proliferation and death
    • Burnstock G. 2002. Purinergic signalling and vascular cell proliferation and death. Arterioscler Thromb Vasc 22: 364- 73.
    • (2002) Arterioscler Thromb Vasc , vol.22 , pp. 364-373
    • Burnstock, G.1
  • 56
    • 38549129745 scopus 로고    scopus 로고
    • P2 receptors in cardiovascular physiology and disease
    • Erlinge D, Burnstock G. 2008. P2 receptors in cardiovascular physiology and disease. Purinergic Signal 4: 1- 20.
    • (2008) Purinergic Signal , vol.4 , pp. 1-20
    • Erlinge, D.1    Burnstock, G.2
  • 57
    • 35548943233 scopus 로고    scopus 로고
    • Purine-mediated signalling triggers eye development
    • Massé K, Bhamra S, Eason R, Dale N, et al. 2007. Purine-mediated signalling triggers eye development. Nature 449: 1058- 62.
    • (2007) Nature , vol.449 , pp. 1058-1062
    • Massé, K.1    Bhamra, S.2    Eason, R.3    Dale, N.4
  • 58
    • 59049106946 scopus 로고    scopus 로고
    • Novel perspectives of neural stem cell differentiation: from neurotransmitters to therapeutics
    • Trujillo CA, Schwindt TT, Martins AH, Alves JM, et al. 2009. Novel perspectives of neural stem cell differentiation: from neurotransmitters to therapeutics. Cytometry A 75: 38- 53.
    • (2009) Cytometry A , vol.75 , pp. 38-53
    • Trujillo, C.A.1    Schwindt, T.T.2    Martins, A.H.3    Alves, J.M.4
  • 59
    • 69649083601 scopus 로고    scopus 로고
    • Coordinate pathways for nucleotide and EGF signaling in cultured adult neural progenitor cells
    • Grimm I, Messemer N, Stanke M, Gachet C, et al. 2009. Coordinate pathways for nucleotide and EGF signaling in cultured adult neural progenitor cells. J Cell Sci 122: 2524- 33.
    • (2009) J Cell Sci , vol.122 , pp. 2524-2533
    • Grimm, I.1    Messemer, N.2    Stanke, M.3    Gachet, C.4
  • 60
    • 79953704482 scopus 로고    scopus 로고
    • Purinergic signalling in embryonic and stem cell development
    • Burnstock G, Ulrich H. 2011. Purinergic signalling in embryonic and stem cell development. Cell Mol Life Sci 68: 1369- 94.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1369-1394
    • Burnstock, G.1    Ulrich, H.2
  • 61
    • 79651472245 scopus 로고    scopus 로고
    • Nucleotides affect neurogenesis and dopaminergic differentiation of mouse fetal midbrain-derived neural precursor cells
    • Delic J, Zimmermann H. 2010. Nucleotides affect neurogenesis and dopaminergic differentiation of mouse fetal midbrain-derived neural precursor cells. Purinergic Signal 6: 417- 28.
    • (2010) Purinergic Signal , vol.6 , pp. 417-428
    • Delic, J.1    Zimmermann, H.2
  • 62
    • 0034764244 scopus 로고    scopus 로고
    • Purinergic signalling: ATP release
    • Bodin P, Burnstock G. 2001. Purinergic signalling: ATP release. Neurochem Res 26: 959- 69.
    • (2001) Neurochem Res , vol.26 , pp. 959-969
    • Bodin, P.1    Burnstock, G.2
  • 64
    • 44449149786 scopus 로고    scopus 로고
    • Identification of a vesicular nucleotide transporter
    • Sawada K, Echigo N, Juge N, Miyaji T, et al. 2008. Identification of a vesicular nucleotide transporter. Proc Natl Acad Sci USA 105: 5683- 6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5683-5686
    • Sawada, K.1    Echigo, N.2    Juge, N.3    Miyaji, T.4
  • 65
    • 84862993885 scopus 로고    scopus 로고
    • Imaging single photons and intrinsic optical signals for studies of vesicular and non-vesicular ATP release from axons
    • Fields RD. 2011. Imaging single photons and intrinsic optical signals for studies of vesicular and non-vesicular ATP release from axons. Front Neuroanat 5: 32.
    • (2011) Front Neuroanat , vol.5 , pp. 32
    • Fields, R.D.1
  • 66
    • 35548942342 scopus 로고    scopus 로고
    • Ecto-nucleotidases, molecular properties and functional impact
    • Zimmermann H, Mishra SK, Shukla V, Langer D, et al. 2007. Ecto-nucleotidases, molecular properties and functional impact. An R Acad Nac Farm 73: 537- 66.
    • (2007) An R Acad Nac Farm , vol.73 , pp. 537-566
    • Zimmermann, H.1    Mishra, S.K.2    Shukla, V.3    Langer, D.4
  • 67
    • 41949083203 scopus 로고    scopus 로고
    • Nucleotide- and nucleoside-converting ectoenzymes: important modulators of purinergic signalling cascade
    • Yegutkin GG. 2008. Nucleotide- and nucleoside-converting ectoenzymes: important modulators of purinergic signalling cascade. Biochim Biophys Acta 1783: 673- 94.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 673-694
    • Yegutkin, G.G.1
  • 68
    • 79955960780 scopus 로고    scopus 로고
    • Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity.
    • Jacobson KA, Linden J, eds. San Diego: Academic Press.
    • Deaglio S, Robson SC. 2011. Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity. In: Jacobson KA, Linden J, eds; Advances in Pharmacology. Pharmacology of Purine and Pyrimidine Receptors. San Diego: Academic Press. p. 301- 32.
    • (2011) Advances in Pharmacology. Pharmacology of Purine and Pyrimidine Receptors , pp. 301-332
    • Deaglio, S.1    Robson, S.C.2
  • 69
    • 80052855507 scopus 로고    scopus 로고
    • Purinergic signalling: from normal behaviour to pathological brain function
    • Burnstock G, Krügel U, Abbracchio MP, Illes P. 2011. Purinergic signalling: from normal behaviour to pathological brain function. Prog Neurobiol 95: 229- 74.
    • (2011) Prog Neurobiol , vol.95 , pp. 229-274
    • Burnstock, G.1    Krügel, U.2    Abbracchio, M.P.3    Illes, P.4
  • 70
    • 33644607461 scopus 로고    scopus 로고
    • Pathophysiology and therapeutic potential of purinergic signaling
    • Burnstock G. 2006. Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 58: 58- 86.
    • (2006) Pharmacol Rev , vol.58 , pp. 58-86
    • Burnstock, G.1
  • 71
    • 0030974128 scopus 로고    scopus 로고
    • Early expression of a novel nucleotide receptor in the neural plate of Xenopus embryos
    • Bogdanov YD, Dale L, King BF, Whittock N, et al. 1997. Early expression of a novel nucleotide receptor in the neural plate of Xenopus embryos. J Biol Chem 272: 12583- 90.
    • (1997) J Biol Chem , vol.272 , pp. 12583-12590
    • Bogdanov, Y.D.1    Dale, L.2    King, B.F.3    Whittock, N.4
  • 73
    • 0034957479 scopus 로고    scopus 로고
    • Sequential expression of three receptor subtypes for extracellular ATP in developing rat skeletal muscle
    • Ryten M, Hoebertz A, Burnstock G. 2001. Sequential expression of three receptor subtypes for extracellular ATP in developing rat skeletal muscle. Dev Dyn 221: 331- 41.
    • (2001) Dev Dyn , vol.221 , pp. 331-341
    • Ryten, M.1    Hoebertz, A.2    Burnstock, G.3
  • 74
    • 20444437170 scopus 로고    scopus 로고
    • Expression of P2X receptors during rat brain development and their inhibitory role on motor axon outgrowth in neural tube explant cultures
    • Cheung K-K, Chan WY, Burnstock G. 2005. Expression of P2X receptors during rat brain development and their inhibitory role on motor axon outgrowth in neural tube explant cultures. Neuroscience 133: 937- 45.
    • (2005) Neuroscience , vol.133 , pp. 937-945
    • Cheung, K.-K.1    Chan, W.Y.2    Burnstock, G.3
  • 75
    • 0026737899 scopus 로고
    • Implantation of the myenteric plexus into the corpus striatum of adult rats: survival of the neurones and glia and interactions with host brain
    • Tew EMM, Anderson PN, Burnstock G. 1992. Implantation of the myenteric plexus into the corpus striatum of adult rats: survival of the neurones and glia and interactions with host brain. Restor Neurol Neurosci 4: 311- 21.
    • (1992) Restor Neurol Neurosci , vol.4 , pp. 311-321
    • Tew, E.M.M.1    Anderson, P.N.2    Burnstock, G.3
  • 76
    • 0030198559 scopus 로고    scopus 로고
    • Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth promoting effect of myenteric plexus explants
    • Höpker VH, Saffrey MJ, Burnstock G. 1996. Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth promoting effect of myenteric plexus explants. Int J Dev Neurosci 14: 439- 51.
    • (1996) Int J Dev Neurosci , vol.14 , pp. 439-451
    • Höpker, V.H.1    Saffrey, M.J.2    Burnstock, G.3
  • 77
    • 0018235052 scopus 로고
    • Direct evidence for ATP release from non-adrenergic, non-cholinergic ("purinergic") nerves in the guinea-pig taenia coli and bladder
    • Burnstock G, Cocks T, Kasakov L, Wong HK. 1978. Direct evidence for ATP release from non-adrenergic, non-cholinergic ("purinergic") nerves in the guinea-pig taenia coli and bladder. Eur J Pharmacol 49: 145- 9.
    • (1978) Eur J Pharmacol , vol.49 , pp. 145-149
    • Burnstock, G.1    Cocks, T.2    Kasakov, L.3    Wong, H.K.4
  • 79
    • 0022612522 scopus 로고
    • Differential effects of α,β-methylene ATP on responses to nerve stimulation in SHR and WKY tail arteries
    • Vidal M, Hicks PE, Langer SZ. 1986. Differential effects of α, β-methylene ATP on responses to nerve stimulation in SHR and WKY tail arteries. Naunyn Schmiedebergs Arch Pharmacol 332: 384- 90.
    • (1986) Naunyn Schmiedebergs Arch Pharmacol , vol.332 , pp. 384-390
    • Vidal, M.1    Hicks, P.E.2    Langer, S.Z.3
  • 80
    • 0029102288 scopus 로고
    • A P2X purinoceptor expressed by a subset of sensory neurons
    • Chen CC, Akopian AN, Sivilotti L, Colquhoun D, et al. 1995. A P2X purinoceptor expressed by a subset of sensory neurons. Nature 377: 428- 31.
    • (1995) Nature , vol.377 , pp. 428-431
    • Chen, C.C.1    Akopian, A.N.2    Sivilotti, L.3    Colquhoun, D.4
  • 81
    • 0031593393 scopus 로고    scopus 로고
    • 3 purinoceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor
    • 3 purinoceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor. Mol Cell Neurosci 12: 256- 68.
    • (1998) Mol Cell Neurosci , vol.12 , pp. 256-268
    • Bradbury, E.J.1    Burnstock, G.2    McMahon, S.B.3
  • 82
    • 0029892771 scopus 로고    scopus 로고
    • A unifying purinergic hypothesis for the initiation of pain
    • Burnstock G. 1996. A unifying purinergic hypothesis for the initiation of pain. Lancet 347: 1604- 5.
    • (1996) Lancet , vol.347 , pp. 1604-1605
    • Burnstock, G.1
  • 83
    • 0033016798 scopus 로고    scopus 로고
    • Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction
    • Burnstock G. 1999. Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction. J Anat 194: 335- 42.
    • (1999) J Anat , vol.194 , pp. 335-342
    • Burnstock, G.1
  • 84
    • 0035413364 scopus 로고    scopus 로고
    • 3 knockout mice reveal a major sensory role for urothelially released ATP
    • 3 knockout mice reveal a major sensory role for urothelially released ATP. J Neurosci 21: 5670- 7.
    • (2001) J Neurosci , vol.21 , pp. 5670-5677
    • Vlaskovska, M.1    Kasakov, L.2    Rong, W.3    Bodin, P.4
  • 85
    • 8844263063 scopus 로고    scopus 로고
    • Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig
    • Rong W, Burnstock G. 2004. Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig. Neuropharmacology 47: 1093- 101.
    • (2004) Neuropharmacology , vol.47 , pp. 1093-1101
    • Rong, W.1    Burnstock, G.2
  • 86
    • 33748534159 scopus 로고    scopus 로고
    • Adenosine 5′-triphosphate and its relationship with other mediators that activate pelvic afferent neurons in the rat colorectum
    • Wynn G, Burnstock G. 2006. Adenosine 5′-triphosphate and its relationship with other mediators that activate pelvic afferent neurons in the rat colorectum. Purinergic Signal 2: 517- 26.
    • (2006) Purinergic Signal , vol.2 , pp. 517-526
    • Wynn, G.1    Burnstock, G.2
  • 88
    • 33947629663 scopus 로고    scopus 로고
    • P2 receptors and chronic pain
    • Inoue K. 2007. P2 receptors and chronic pain. Purinergic Signal 3: 135- 44.
    • (2007) Purinergic Signal , vol.3 , pp. 135-144
    • Inoue, K.1
  • 89
    • 67650590969 scopus 로고    scopus 로고
    • Purinergic receptors and pain
    • Burnstock G. 2009. Purinergic receptors and pain. Curr Pharm Design 15: 1717- 35.
    • (2009) Curr Pharm Design , vol.15 , pp. 1717-1735
    • Burnstock, G.1
  • 90
    • 33745738972 scopus 로고    scopus 로고
    • Purinergic signalling in neuron-glial interactions
    • Fields D, Burnstock G. 2006. Purinergic signalling in neuron-glial interactions. Nat Rev Neurosci 7: 423- 36.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 423-436
    • Fields, D.1    Burnstock, G.2
  • 91
    • 46449134214 scopus 로고    scopus 로고
    • Purinergic signalling and disorders of the central nervous system
    • Burnstock G. 2008. Purinergic signalling and disorders of the central nervous system. Nat Rev Drug Discov 7: 575- 90.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 575-590
    • Burnstock, G.1
  • 92
    • 84857061358 scopus 로고    scopus 로고
    • Eds: Special Issue. Purinergic signalling in epilepsy
    • Boisson D, Burnstock G. 2010. Eds: Special Issue. Purinergic signalling in epilepsy. Open Neurosci J 4: 23- 113.
    • (2010) Open Neurosci J , vol.4 , pp. 23-113
    • Boisson, D.1    Burnstock, G.2
  • 93
    • 78651059794 scopus 로고    scopus 로고
    • Therapeutic potential of purinergic signalling for diseases of the urinary tract
    • Burnstock G. 2011. Therapeutic potential of purinergic signalling for diseases of the urinary tract. BJU Int 107: 192- 204.
    • (2011) BJU Int , vol.107 , pp. 192-204
    • Burnstock, G.1
  • 94
    • 9444244400 scopus 로고    scopus 로고
    • Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures
    • Ryten M, Yang SY, Dunn PM, Goldspink G, et al. 2004. Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures. FASEB J 18: 1404- 6.
    • (2004) FASEB J , vol.18 , pp. 1404-1406
    • Ryten, M.1    Yang, S.Y.2    Dunn, P.M.3    Goldspink, G.4
  • 95
    • 50249107634 scopus 로고    scopus 로고
    • Commentary. Purinergic receptors as future targets for treatment of functional GI disorders
    • Burnstock G. 2008. Commentary. Purinergic receptors as future targets for treatment of functional GI disorders. Gut 57: 1193- 4.
    • (2008) Gut , vol.57 , pp. 1193-1194
    • Burnstock, G.1
  • 100
    • 41049087422 scopus 로고    scopus 로고
    • A functional study of purinergic signalling in the normal and pathological rabbit corpus cavernosum
    • Calvert RC, Khan MA, Thompson CS, Mikhailidis DP, et al. 2008. A functional study of purinergic signalling in the normal and pathological rabbit corpus cavernosum. BJU Int 101: 1043- 7.
    • (2008) BJU Int , vol.101 , pp. 1043-1047
    • Calvert, R.C.1    Khan, M.A.2    Thompson, C.S.3    Mikhailidis, D.P.4
  • 101
    • 64449083384 scopus 로고    scopus 로고
    • Management of erectile function by purinergic P2 receptors in diabetic rat
    • Gür S, Kadowitz PJ, Abdel-Mageed AS, Kendirci M, et al. 2009. Management of erectile function by purinergic P2 receptors in diabetic rat. J Urol 181: 2382.
    • (2009) J Urol , vol.181 , pp. 2382
    • Gür, S.1    Kadowitz, P.J.2    Abdel-Mageed, A.S.3    Kendirci, M.4
  • 102
    • 80054840705 scopus 로고    scopus 로고
    • Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection
    • Séror C, Melki MT, Subra F, Raza SQ, et al. 2011. Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection. J Exp Med 208: 1823- 34.
    • (2011) J Exp Med , vol.208 , pp. 1823-1834
    • Séror, C.1    Melki, M.T.2    Subra, F.3    Raza, S.Q.4
  • 104
    • 44849136452 scopus 로고    scopus 로고
    • Effect of extracellular ATP on the growth of hormone refractory prostate cancer in vivo
    • Shabbir M, Thompson CS, Jarmulowicz M, Mikhailidis DP, et al. 2008. Effect of extracellular ATP on the growth of hormone refractory prostate cancer in vivo. BJU Int 102: 108- 12.
    • (2008) BJU Int , vol.102 , pp. 108-112
    • Shabbir, M.1    Thompson, C.S.2    Jarmulowicz, M.3    Mikhailidis, D.P.4
  • 105
    • 60349123127 scopus 로고    scopus 로고
    • Purinergic receptor-mediated effects of adenosine 5′-triphosphate in urological malignant diseases
    • Shabbir M, Burnstock G. 2009. Purinergic receptor-mediated effects of adenosine 5′-triphosphate in urological malignant diseases. Int J Urol 16: 143- 50.
    • (2009) Int J Urol , vol.16 , pp. 143-150
    • Shabbir, M.1    Burnstock, G.2
  • 107
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg J, Smyth MJ. 2010. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 29: 5346- 58.
    • (2010) Oncogene , vol.29 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.J.2
  • 108
    • 0020683915 scopus 로고
    • Treatment of human tumor cells with ADP or ATP yields arrest of growth in the S phase of the cell cycle
    • Rapaport E. 1983. Treatment of human tumor cells with ADP or ATP yields arrest of growth in the S phase of the cell cycle. J Cell Physiol 114: 279- 83.
    • (1983) J Cell Physiol , vol.114 , pp. 279-283
    • Rapaport, E.1
  • 109
    • 79955153842 scopus 로고    scopus 로고
    • Altered purinergic signaling in CD73-deficient mice inhibits tumor progression
    • Yegutkin GG, Marttila-Ichihara F, Karikoski M, Niemela J, et al. 2011. Altered purinergic signaling in CD73-deficient mice inhibits tumor progression. Eur J Immunol 41: 1231- 41.
    • (2011) Eur J Immunol , vol.41 , pp. 1231-1241
    • Yegutkin, G.G.1    Marttila-Ichihara, F.2    Karikoski, M.3    Niemela, J.4
  • 110
    • 79960453380 scopus 로고    scopus 로고
    • P2X7 receptor-deficient mice are susceptible to bone cancer pain
    • Hansen RR, Nielsen CK, Nasser A, Thomsen SI, et al. 2011. P2X7 receptor-deficient mice are susceptible to bone cancer pain. Pain 152: 1766- 76.
    • (2011) Pain , vol.152 , pp. 1766-1776
    • Hansen, R.R.1    Nielsen, C.K.2    Nasser, A.3    Thomsen, S.I.4
  • 111
    • 69249220030 scopus 로고    scopus 로고
    • Acupuncture: a novel hypothesis for the involvement of purinergic signalling
    • Burnstock G. 2009. Acupuncture: a novel hypothesis for the involvement of purinergic signalling. Med Hypotheses 73: 470- 2.
    • (2009) Med Hypotheses , vol.73 , pp. 470-472
    • Burnstock, G.1
  • 112
    • 36148972023 scopus 로고    scopus 로고
    • Introduction: ATP and its metabolites as potent extracellular agonists.
    • Schwiebert EM, ed. San Diego: Academic Press.
    • Burnstock G. 2003. Introduction: ATP and its metabolites as potent extracellular agonists. In Schwiebert EM, ed; Current Topics in Membranes, Vol 54. Purinergic Receptors and Signalling. San Diego: Academic Press. p. 1- 27.
    • (2003) Current Topics in Membranes, Vol 54. Purinergic Receptors and Signalling , pp. 1-27
    • Burnstock, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.