-
1
-
-
0033838716
-
Regulation of cell function by Rho family GTPases
-
Bokoch, G.M. (2000) Regulation of cell function by Rho family GTPases. Immunol. Res., 21, 139-148.
-
(2000)
Immunol. Res.
, vol.21
, pp. 139-148
-
-
Bokoch, G.M.1
-
2
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A. (1998) Rho GTPases and the actin cytoskeleton. Science, 279, 509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
3
-
-
0034715895
-
Rho GTPases: signaling, migration, and invasion
-
Schmitz, A.A. et al. (2000) Rho GTPases: signaling, migration, and invasion. Exp. Cell Res., 261, 1-12.
-
(2000)
Exp. Cell Res.
, vol.261
, pp. 1-12
-
-
Schmitz, A.A.1
-
4
-
-
50049129364
-
P21-activated kinase is required for mitotic progression and regulates Plk1
-
Maroto, B. et al. (2008) P21-activated kinase is required for mitotic progression and regulates Plk1. Oncogene, 27, 4900-4908.
-
(2008)
Oncogene
, vol.27
, pp. 4900-4908
-
-
Maroto, B.1
-
5
-
-
33846646483
-
Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes
-
Halet, G. et al. (2007) Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes. Dev. Cell, 12, 309-317.
-
(2007)
Dev. Cell
, vol.12
, pp. 309-317
-
-
Halet, G.1
-
6
-
-
55849145076
-
Transforming human blood stem and progenitor cells: a new way forward in leukemia modeling
-
Mulloy, J.C. et al. (2008) Transforming human blood stem and progenitor cells: a new way forward in leukemia modeling. Cell Cycle, 7, 3314-3319.
-
(2008)
Cell Cycle
, vol.7
, pp. 3314-3319
-
-
Mulloy, J.C.1
-
7
-
-
81155149508
-
Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia
-
Mizukawa, B. et al. (2011) Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia. Blood, 118, 5235-5245.
-
(2011)
Blood
, vol.118
, pp. 5235-5245
-
-
Mizukawa, B.1
-
8
-
-
0142116231
-
Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling
-
Walmsley, M.J. et al. (2003) Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. Science, 302, 459-462.
-
(2003)
Science
, vol.302
, pp. 459-462
-
-
Walmsley, M.J.1
-
9
-
-
1842426910
-
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration
-
Wells, C.M. et al. (2004) Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J. Cell Sci., 117, 1259-1268.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1259-1268
-
-
Wells, C.M.1
-
10
-
-
0028800305
-
Activation of Rac1, RhoA, and mitogenactivated protein kinases is required for Ras transformation
-
Khosravi-Far, R. et al. (1995) Activation of Rac1, RhoA, and mitogenactivated protein kinases is required for Ras transformation. Mol. Cell. Biol., 15, 6443-6453.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6443-6453
-
-
Khosravi-Far, R.1
-
11
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden, A. et al. (1995) Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell, 81, 1147-1157.
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
-
12
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso, O.A. et al. (1995) The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell, 81, 1137-1146.
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
-
13
-
-
0030597239
-
Three paths to stress relief
-
Canman, C.E. et al. (1996) Three paths to stress relief. Nature, 384, 213-214.
-
(1996)
Nature
, vol.384
, pp. 213-214
-
-
Canman, C.E.1
-
14
-
-
0034602967
-
Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression
-
Jefferies, C.A. et al. (2000) Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression. J. Biol. Chem., 275, 3114-3120.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3114-3120
-
-
Jefferies, C.A.1
-
15
-
-
79957580066
-
Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1
-
Ungefroren, H. et al. (2011) Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1. Mol. Cancer, 10, 67.
-
(2011)
Mol. Cancer
, vol.10
, pp. 67
-
-
Ungefroren, H.1
-
16
-
-
36348966706
-
Rho GTPases: functions and association with cancer
-
Ellenbroek, S.I. et al. (2007) Rho GTPases: functions and association with cancer. Clin. Exp. Metastasis, 24, 657-672.
-
(2007)
Clin. Exp. Metastasis
, vol.24
, pp. 657-672
-
-
Ellenbroek, S.I.1
-
17
-
-
10644286120
-
Pleiotropic effects of statins
-
Liao, J.K. et al. (2005) Pleiotropic effects of statins. Annu. Rev. Pharmacol. Toxicol., 45, 89-118.
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 89-118
-
-
Liao, J.K.1
-
18
-
-
0031409639
-
Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats
-
Inano, H. et al. (1997) Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats. Carcinogenesis, 18, 1723-1727.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1723-1727
-
-
Inano, H.1
-
19
-
-
0027978838
-
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice
-
Narisawa, T. et al. (1994) Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice. Carcinogenesis, 15, 2045-2048.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2045-2048
-
-
Narisawa, T.1
-
20
-
-
84891740035
-
Chemopreventive strategies in hepatocellular carcinoma
-
Singh, S. et al. (2014) Chemopreventive strategies in hepatocellular carcinoma. Nat. Rev. Gastroenterol. Hepatol., 11, 45-54.
-
(2014)
Nat. Rev. Gastroenterol. Hepatol.
, vol.11
, pp. 45-54
-
-
Singh, S.1
-
21
-
-
77951709095
-
Pleiotropic effects of statins - Basic research and clinical perspectives
-
Zhou, Q. et al. (2010) Pleiotropic effects of statins - Basic research and clinical perspectives. Circ. J., 74, 818-826.
-
(2010)
Circ. J.
, vol.74
, pp. 818-826
-
-
Zhou, Q.1
-
22
-
-
80054787201
-
Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors
-
Hamalukic, M. et al. (2011) Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors. PLoS One, 6, e26413.
-
(2011)
PLoS One
, vol.6
, pp. e26413
-
-
Hamalukic, M.1
-
23
-
-
80051540959
-
Early requirement of Rac1 in a mouse model of pancreatic cancer
-
730.e1-7
-
Heid, I. et al. (2011) Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology, 141, 719-730, 730.e1-7.
-
(2011)
Gastroenterology
, vol.141
, pp. 719-730
-
-
Heid, I.1
-
24
-
-
34548583283
-
Requirement for Rac1 in a K-ras induced lung cancer in the mouse
-
Kissil, J.L. et al. (2007) Requirement for Rac1 in a K-ras induced lung cancer in the mouse. Cancer Res., 67, 8089-8094.
-
(2007)
Cancer Res.
, vol.67
, pp. 8089-8094
-
-
Kissil, J.L.1
-
25
-
-
79951889870
-
K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity
-
Samuel, M.S. et al. (2011) K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity. PLoS One, 6, e17143.
-
(2011)
PLoS One
, vol.6
, pp. e17143
-
-
Samuel, M.S.1
-
26
-
-
77953480305
-
Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo
-
Wang, Z. et al. (2010) Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo. Oncogene, 29, 3362-3373.
-
(2010)
Oncogene
, vol.29
, pp. 3362-3373
-
-
Wang, Z.1
-
27
-
-
0037142034
-
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours
-
Malliri, A. et al. (2002) Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. Nature, 417, 867-871.
-
(2002)
Nature
, vol.417
, pp. 867-871
-
-
Malliri, A.1
-
28
-
-
0032585635
-
Rac1 is required for the formation of three germ layers during gastrulation
-
Sugihara, K. et al. (1998) Rac1 is required for the formation of three germ layers during gastrulation. Oncogene, 17, 3427-3433.
-
(1998)
Oncogene
, vol.17
, pp. 3427-3433
-
-
Sugihara, K.1
-
29
-
-
0034063279
-
Hepatocyte-specific expression of Cre recombinase
-
Kellendonk, C. et al. (2000) Hepatocyte-specific expression of Cre recombinase. Genesis, 26, 151-153.
-
(2000)
Genesis
, vol.26
, pp. 151-153
-
-
Kellendonk, C.1
-
30
-
-
0034059141
-
DNA excision in liver by an albumin-Cre transgene occurs progressively with age
-
Postic, C. et al. (2000) DNA excision in liver by an albumin-Cre transgene occurs progressively with age. Genesis, 26, 149-150.
-
(2000)
Genesis
, vol.26
, pp. 149-150
-
-
Postic, C.1
-
31
-
-
0025141973
-
Perinatal mouse liver carcinogenesis as a sensitive carcinogenesis model and the role of the sex hormonal environment in tumor development
-
Vesselinovitch, S.D. (1990) Perinatal mouse liver carcinogenesis as a sensitive carcinogenesis model and the role of the sex hormonal environment in tumor development. Prog. Clin. Biol. Res., 331, 53-68.
-
(1990)
Prog. Clin. Biol. Res.
, vol.331
, pp. 53-68
-
-
Vesselinovitch, S.D.1
-
32
-
-
79952118383
-
Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen
-
Rignall, B. et al. (2011) Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen. Carcinogenesis, 32, 52-57.
-
(2011)
Carcinogenesis
, vol.32
, pp. 52-57
-
-
Rignall, B.1
-
33
-
-
0027235542
-
Sex-dependent expression of class pi glutathione S-transferase during chemical hepatocarcinogenesis in B6C3F1 mice
-
Hatayama, I. et al. (1993) Sex-dependent expression of class pi glutathione S-transferase during chemical hepatocarcinogenesis in B6C3F1 mice. Carcinogenesis, 14, 537-538.
-
(1993)
Carcinogenesis
, vol.14
, pp. 537-538
-
-
Hatayama, I.1
-
34
-
-
79952562134
-
Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents
-
Fritz, G. et al. (2011) Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents. Br. Med. Bull., 97, 17-26.
-
(2011)
Br. Med. Bull.
, vol.97
, pp. 17-26
-
-
Fritz, G.1
-
35
-
-
34547805294
-
Change in expression of MGMT during maturation of human monocytes into dendritic cells
-
Briegert, M. et al. (2007) Change in expression of MGMT during maturation of human monocytes into dendritic cells. DNA Repair (Amst)., 6, 1255-1263.
-
(2007)
DNA Repair (Amst).
, vol.6
, pp. 1255-1263
-
-
Briegert, M.1
-
36
-
-
16644392782
-
Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation
-
Olive, P.L. (2004) Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation. Methods Cell Biol., 75, 355-373.
-
(2004)
Methods Cell Biol.
, vol.75
, pp. 355-373
-
-
Olive, P.L.1
-
37
-
-
0035936026
-
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors
-
Aydinlik, H. et al. (2001) Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene, 20, 7812-7816.
-
(2001)
Oncogene
, vol.20
, pp. 7812-7816
-
-
Aydinlik, H.1
-
38
-
-
0032939619
-
Rho GTPases are over-expressed in human tumors
-
Fritz, G. et al. (1999) Rho GTPases are over-expressed in human tumors. Int. J. Cancer, 81, 682-687.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 682-687
-
-
Fritz, G.1
-
39
-
-
0034659739
-
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b
-
Schnelzer, A. et al. (2000) Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b. Oncogene, 19, 3013-3020.
-
(2000)
Oncogene
, vol.19
, pp. 3013-3020
-
-
Schnelzer, A.1
-
40
-
-
0037108681
-
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital
-
Loeppen, S. et al. (2002) Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital. Cancer Res., 62, 5685-5688.
-
(2002)
Cancer Res.
, vol.62
, pp. 5685-5688
-
-
Loeppen, S.1
-
41
-
-
0037191930
-
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism
-
Cadoret, A. et al. (2002) New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism. Oncogene, 21, 8293-8301.
-
(2002)
Oncogene
, vol.21
, pp. 8293-8301
-
-
Cadoret, A.1
-
42
-
-
84857364721
-
A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells
-
Zhu, G. et al. (2012) A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells. Oncogene, 31, 1001-1012.
-
(2012)
Oncogene
, vol.31
, pp. 1001-1012
-
-
Zhu, G.1
-
43
-
-
53949096505
-
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance betacatenin/ TCF-dependent transcription in colorectal cancer cells
-
Buongiorno, P. et al. (2008) Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance betacatenin/ TCF-dependent transcription in colorectal cancer cells. Mol. Cancer, 7, 73.
-
(2008)
Mol. Cancer
, vol.7
, pp. 73
-
-
Buongiorno, P.1
-
44
-
-
41949105179
-
Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling
-
Wu, X. et al. (2008) Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling. Cell, 133, 340-353.
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
-
45
-
-
80052338841
-
A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition
-
Howard, S. et al. (2011) A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition. PLoS One, 6, e23899.
-
(2011)
PLoS One
, vol.6
, pp. e23899
-
-
Howard, S.1
-
46
-
-
38149027162
-
Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas
-
Audard, V. et al. (2008) Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas. Pancreas, 36, 80-83.
-
(2008)
Pancreas
, vol.36
, pp. 80-83
-
-
Audard, V.1
-
47
-
-
0035158750
-
RAC1 regulates adherens junctions through endocytosis of E-cadherin
-
Akhtar, N. et al. (2001) RAC1 regulates adherens junctions through endocytosis of E-cadherin. Mol. Biol. Cell, 12, 847-862.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 847-862
-
-
Akhtar, N.1
-
48
-
-
0030718609
-
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
-
Takaishi, K. et al. (1997) Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol., 139, 1047-1059.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1047-1059
-
-
Takaishi, K.1
-
49
-
-
3342986329
-
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments
-
Izumi, G. et al. (2004) Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments. J. Cell Biol., 166, 237-248.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 237-248
-
-
Izumi, G.1
-
50
-
-
77950627707
-
Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression
-
Woodcock, S.A. et al. (2010) Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression. Curr. Biol., 20, 669-675.
-
(2010)
Curr. Biol.
, vol.20
, pp. 669-675
-
-
Woodcock, S.A.1
-
51
-
-
36749022214
-
The DNA damage response: ten years after
-
Harper, J.W. et al. (2007) The DNA damage response: ten years after. Mol. Cell, 28, 739-745.
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
-
52
-
-
55249116558
-
Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
-
Kinner, A. et al. (2008) Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Res., 36, 5678-5694.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 5678-5694
-
-
Kinner, A.1
-
53
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou, E.P. et al. (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem., 273, 5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
-
54
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATRdependent manner in response to replicational stress
-
Ward, I.M. et al. (2001) Histone H2AX is phosphorylated in an ATRdependent manner in response to replicational stress. J. Biol. Chem., 276, 47759-47762.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
-
55
-
-
77951935474
-
Mechanism of p53 stabilization by ATM after DNA damage
-
Cheng, Q. et al. (2010) Mechanism of p53 stabilization by ATM after DNA damage. Cell Cycle, 9, 472-478.
-
(2010)
Cell Cycle
, vol.9
, pp. 472-478
-
-
Cheng, Q.1
-
56
-
-
33845888229
-
c-Fos is required for excision repair of UVlight induced DNA lesions by triggering the re-synthesis of XPF
-
Christmann, M. et al. (2006) c-Fos is required for excision repair of UVlight induced DNA lesions by triggering the re-synthesis of XPF. Nucleic Acids Res., 34, 6530-6539.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 6530-6539
-
-
Christmann, M.1
-
57
-
-
0242331221
-
Mechanisms of human DNA repair: an update
-
Christmann, M. et al. (2003) Mechanisms of human DNA repair: an update. Toxicology, 193, 3-34.
-
(2003)
Toxicology
, vol.193
, pp. 3-34
-
-
Christmann, M.1
-
58
-
-
34447314728
-
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
-
Kaina, B. et al. (2007) MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair (Amst)., 6, 1079-1099.
-
(2007)
DNA Repair (Amst).
, vol.6
, pp. 1079-1099
-
-
Kaina, B.1
-
59
-
-
84871260739
-
Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1
-
Chowdhury, G. et al. (2012) Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1. Biochemistry, 51, 9995-10007.
-
(2012)
Biochemistry
, vol.51
, pp. 9995-10007
-
-
Chowdhury, G.1
-
60
-
-
84875906348
-
Rac1 modulates acute and subacute genotoxininduced hepatic stress responses, fibrosis and liver aging
-
Bopp, A. et al. (2013) Rac1 modulates acute and subacute genotoxininduced hepatic stress responses, fibrosis and liver aging. Cell Death Dis., 4, e558.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e558
-
-
Bopp, A.1
-
61
-
-
0033215188
-
Rac-dependent anti-apoptotic signaling by the insulin receptor cytoplasmic domain
-
Boehm, J.E. et al. (1999) Rac-dependent anti-apoptotic signaling by the insulin receptor cytoplasmic domain. J. Biol. Chem., 274, 28632-28636.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28632-28636
-
-
Boehm, J.E.1
-
62
-
-
0030772153
-
Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase
-
Lores, P. et al. (1997) Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase. Oncogene, 15, 601-605.
-
(1997)
Oncogene
, vol.15
, pp. 601-605
-
-
Lores, P.1
-
63
-
-
0033912699
-
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase
-
Genot, E.M. et al. (2000) The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Mol. Cell. Biol., 20, 5469-5478.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5469-5478
-
-
Genot, E.M.1
-
64
-
-
41849119497
-
A brief introduction to FOXOlogy
-
Burgering, B.M. (2008) A brief introduction to FOXOlogy. Oncogene, 27, 2258-2262.
-
(2008)
Oncogene
, vol.27
, pp. 2258-2262
-
-
Burgering, B.M.1
-
65
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema, R.H. et al. (2000) AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature, 404, 782-787.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
-
66
-
-
84878532413
-
Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver
-
Konstandi, M. et al. (2013) Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver. Am. J. Physiol. Endocrinol. Metab., 304, E1118-E1128.
-
(2013)
Am. J. Physiol. Endocrinol. Metab.
, vol.304
, pp. E1118-E1128
-
-
Konstandi, M.1
-
67
-
-
43149111604
-
Functional interaction between FOXO3a and ATM regulates DNA damage response
-
Tsai, W.B. et al. (2008) Functional interaction between FOXO3a and ATM regulates DNA damage response. Nat. Cell Biol., 10, 460-467.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 460-467
-
-
Tsai, W.B.1
-
68
-
-
84869082071
-
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin
-
Min, L. et al. (2012) Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin. Nat. Cell Biol., 14, 1203-1211.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1203-1211
-
-
Min, L.1
-
69
-
-
0030883583
-
Rac1 is required for cell proliferation and G2/M progression
-
Moore, K.A. et al. (1997) Rac1 is required for cell proliferation and G2/M progression. Biochem. J., 326 (Pt 1), 17-20.
-
(1997)
Biochem. J.
, vol.326
, pp. 17-20
-
-
Moore, K.A.1
-
70
-
-
0035962664
-
Histone H3 phosphorylation and cell division
-
Hans, F. et al. (2001) Histone H3 phosphorylation and cell division. Oncogene, 20, 3021-3027.
-
(2001)
Oncogene
, vol.20
, pp. 3021-3027
-
-
Hans, F.1
-
71
-
-
0029802561
-
RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase
-
Joneson, T. et al. (1996) RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science, 274, 1374-1376.
-
(1996)
Science
, vol.274
, pp. 1374-1376
-
-
Joneson, T.1
-
72
-
-
0030298138
-
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/ SAPK MAP kinase cascade
-
Lamarche, N. et al. (1996) Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/ SAPK MAP kinase cascade. Cell, 87, 519-529.
-
(1996)
Cell
, vol.87
, pp. 519-529
-
-
Lamarche, N.1
-
73
-
-
0029101360
-
An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
-
Olson, M.F. et al. (1995) An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science, 269, 1270-1272.
-
(1995)
Science
, vol.269
, pp. 1270-1272
-
-
Olson, M.F.1
-
74
-
-
0035958923
-
Rac1 protects epithelial cells against anoikis
-
Coniglio, S.J. et al. (2001) Rac1 protects epithelial cells against anoikis. J. Biol. Chem., 276, 28113-28120.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28113-28120
-
-
Coniglio, S.J.1
-
75
-
-
33745815084
-
Nox1-dependent reactive oxygen generation is regulated by Rac1
-
Cheng, G. et al. (2006) Nox1-dependent reactive oxygen generation is regulated by Rac1. J. Biol. Chem., 281, 17718-17726.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 17718-17726
-
-
Cheng, G.1
-
76
-
-
33645285957
-
Regulation of NADPH oxidases: the role of Rac proteins
-
Hordijk, P.L. (2006) Regulation of NADPH oxidases: the role of Rac proteins. Circ. Res., 98, 453-462.
-
(2006)
Circ. Res.
, vol.98
, pp. 453-462
-
-
Hordijk, P.L.1
-
77
-
-
0023701345
-
Analysis of antioxidant defense systems during rat hepatocarcinogenesis
-
Vo, T.K. et al. (1988) Analysis of antioxidant defense systems during rat hepatocarcinogenesis. Carcinogenesis, 9, 2009-2013.
-
(1988)
Carcinogenesis
, vol.9
, pp. 2009-2013
-
-
Vo, T.K.1
-
78
-
-
84884898261
-
Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse
-
Lin, H. et al. (2013) Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse. PLoS One, 8, e74130.
-
(2013)
PLoS One
, vol.8
, pp. e74130
-
-
Lin, H.1
|