Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1

Biochemistry

Volumn 51, Issue 50, 2012, Pages 9995-10007

  Chowdhury, Goutam ^a   Calcutt, M Wade ^a   Nagy, Leslie D ^a   Guengerich, F Peter ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; C-H BOND; CATALYTIC EFFICIENCIES; CYTOCHROME P450; DENITROSATION; DEUTERIUM ISOTOPE EFFECT; GENERAL PATTERNS; INTRINSIC KINETICS; LAG PHASE; MINOR PRODUCTS; N-NITROSODIMETHYLAMINE; PROCESSIVITY; RAT LIVER MICROSOMES; RATE LIMITING; SINGLE MOLECULE;

ALDEHYDES; CARBOXYLIC ACIDS; CATALYTIC OXIDATION; DEUTERIUM; EXPERIMENTS; NITROSAMINES; ORGANIC COMPOUNDS; RATS;

OXIDATION;

ALDEHYDE; CARBOXYLIC ACID; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; DEUTERIUM; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE;

ARTICLE; CATALYST; CHEMICAL BOND; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HYDROGEN BOND; KINETICS; LIVER MICROSOME; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; SYNTHESIS;

ANIMALS; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; DEUTERIUM; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; HUMANS; KINETICS; MALE; MICROSOMES, LIVER; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84871260739     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301092c     Document Type: Article

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