Anti-inflammatory activities of gouania leptostachya methanol extract and its constituent resveratrol

Phytotherapy Research

Volumn 29, Issue 3, 2015, Pages 381-392

  Dung, To Thi Mai ^a   Lee, Jongsung ^b   Kim, Eunji ^a   Yoo, Byong Chul ^c   Ha, Van Thai ^a   Kim, Yong ^a   Yoon, Deok Hyo ^d   Hong, Sungyoul ^a   Baek, Kwang Soo ^a   Sung, Nak Yoon ^a   Kim, Tae Woong ^a,d   Kim, Jong Hoon ^e   Cho, Jae Youl ^a  

^a Sungkyunkwan University   (South Korea)

^b Eulji University   (South Korea)

^c National Cancer Center   (South Korea)

^d Kangwon National University   (South Korea)

^e Chonbuk National University   (South Korea)

Author keywords

anti inflammatory; gastritis; Gouania leptostachya DC. var. tonkinensis Pitard; NF B; Rhamnaceae; Src

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GOUANIA LEPTOSTACHYA EXTRACT; I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; METHANOL; NITRIC OXIDE; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RESVERATROL; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NF-KAPPAB INHIBITOR ALPHA; NOS2 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE; STILBENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANALYSIS; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GASTRITIS; GOUANIA LEPTOSTACHYA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHYTOCHEMISTRY; PLANT LEAF; PROTEIN EXPRESSION; RHAMNACEAE; SHOOT; SOLVENT EXTRACTION; THAILAND; TRADITIONAL MEDICINE; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

GOUANIA; MUS; RHAMNACEAE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; GASTRITIS; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; RHAMNACEAE; STILBENES; THAILAND;

EID: 84924333790     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5262     Document Type: Article

References (48)

1. Almela L, Sanchez-Munoz B, Fernandez-Lopez JA, Roca MJ, Rabe V,. 2006. Liquid chromatograpic-mass spectrometric analysis of phenolics and free radical scavenging activity of rosemary extract from different raw material. J Chromatogr A 1120: 221-229.
2. Arlt A, Muerkoster SS, Schafer H,. 2013. Targeting apoptosis pathways in pancreatic cancer. Cancer Lett 332: 346-358.
3. Ayele Y, Kim JA, Park E, et al,. 2013. A Methanol Extract of Adansonia digitata L. Leaves Inhibits Pro-Inflammatory iNOS Possibly via the Inhibition of NF-kappaB Activation. Biomol Ther (Seoul) 21: 146-152.
4. Back SS, Kim J, Choi D, Lee ES, Choi SY, Han K,. 2013. Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor. BMB Rep 46: 322-327.
5. Bognar E, Sarszegi Z, Szabo A, et al,. 2013. Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol. PLoS One 8: e65355.
6. Byeon SE, Yi YS, Oh J, Yoo BC, Hong S, Cho JY,. 2012. The role of Src kinase in macrophage-mediated inflammatory responses. Mediators Inflamm 2012: 512926.
7. Byeon SE, Yu T, Yang Y, et al,. 2013. Hydroquinone regulates hemeoxygenase-1 expression via modulation of Src kinase activity through thiolation of cysteine residues. Free Radic Biol Med 57: 105-118.
8. Chiurchiu V, Maccarrone M,. 2011. Chronic inflammatory disorders and their redox control: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 15: 2605-2641.
9. Cho JE, Park S, Lee H, Cho SN, Kim YS,. 2013. Mycobacterium tuberculosis-induced expression of granulocyte-macrophage colony stimulating factor is mediated by PI3-K/MEK1/p38 MAPK signaling pathway. BMB Rep 46: 213-218.
10. Chu AJ,. 2014. Antagonism by bioactive polyphenols against inflammation: a systematic view. Inflamm Allergy Drug Targets 13: 34-64.
11. Endale M, Park SC, Kim S, et al,. 2013. Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-kappaB-induced inflammatory mediators production in RAW 264.7 cells. Immunobiology 218: 1452-1467.
12. Fukata M, Abreu MT,. 2009. Pathogen recognition receptors, cancer and inflammation in the gut. Curr Opin Pharmacol 9: 680-687.
13. Hyun B, Shin S, Lee A, et al,. 2013. Metformin Down-regulates TNF-alpha Secretion via Suppression of Scavenger Receptors in Macrophages. Immune Netw 13: 123-132.
14. Ibrahim Abdelwahab S, Syaed Koko W, Mohamed Elhassan Taha M, et al,. 2012. In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-kappaB translocation. Eur J Pharmacol 678: 61-70.
15. Jeong D, Yang WS, Yang Y, et al,. 2013. In vitro and in vivo anti-inflammatory effect of Rhodomyrtus tomentosa methanol extract. J Ethnopharmacol 146: 205-213.
16. Jutras I, Desjardins M,. 2005. Phagocytosis: at the crossroads of innate and adaptive immunity. Annu Rev Cell Dev Biol 21: 511-527.
17. Kennelly EJ, Lewis WH, Winter RE, Johnson S, Elvin-Lewis M, Gossling J,. 1993. Triterpenoid saponins from Gouania lupuloides. J Nat Prod 56: 402-410.
18. Kim DH, Chung JH, Yoon JS, et al,. 2013a. Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-kappaB in LPS-stimulated RAW264.7 cells and mouse liver. J Ginseng Res 37: 54-63.
19. Kim HJ, Park GM, Kim JK,. 2013b. Anti-inflammatory effect of pristimerin on lipopolysaccharide-induced inflammatory responses in murine macrophages. Arch Pharm Res 36: 495-500.
20. Kim M, Lim SJ, Oidovsambuu S, Nho CW,. 2014. Gnetin H isolated from Paeonia anomala inhibits FcepsilonRI-mediated mast cell signaling and degranulation. J Ethnopharmacol 154: 798-806.
21. Kim MH, Son YJ, Lee SY, et al,. 2013c. JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide. Biochem Pharmacol 86: 1747-1761.
22. Kim MY, Cho JY,. 2013a. 20S-dihydroprotopanaxadiol, a ginsenoside derivative, boosts innate immune responses of monocytes and macrophages. J Ginseng Res 37: 293-299.
23. Kim MY, Cho JY,. 2013b. 20S-dihydroprotopanaxatriol modulates functional activation of monocytes and macrophages. J Ginseng Res 37: 300-307.
24. Kim YM, Kim JH, Kwon HM, et al,. 2013d. Korean Red Ginseng protects endothelial cells from serum-deprived apoptosis by regulating Bcl-2 family protein dynamics and caspase S-nitrosylation. J Ginseng Res 37: 413-424.
25. Klausen K, Mortensen AG, Laursen B, Haselmann KF, Jespersen BM, Fomsgaard IS,. 2010. Phenolic compounds in different barley varieties: identification by tandem mass spectrometry (QStar) and NMR; quantification by liquid chromatography triple quadrupole-linear ion trap mass spectrometry (Q-Trap). Nat Prod Commun 5: 407-414.
26. Kuka M, Baronio R, Valentini S, et al,. 2010. Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists. PLoS One 5: e11491.
27. Kwon DJ, Bae YS, Ju SM, Youn GS, Choi SY, Park J,. 2014. Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-kappaB and JNK activation in RAW 264.7 macrophages. BMB Rep 47: 318-323.
28. Liu G, Place AT, Chen Z, et al,. 2012. ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration. Blood 120: 1942-1952.
29. Luskova P, Draber P,. 2004. Modulation of the Fcepsilon receptor I signaling by tyrosine kinase inhibitors: search for therapeutic targets of inflammatory and allergy diseases. Curr Pharm Des 10: 1727-1737.
30. Mukhopadhyay S, Malik P, Arora SK, Mukherjee TK,. 2014. Intercellular adhesion molecule-1 as a drug target in asthma and rhinitis. Respirology 19: 508-513.
31. Nagata M,. 2005. Inflammatory cells and oxygen radicals. Curr Drug Targets Inflamm Allergy 4: 503-504.
32. Panyaphu K, On TV, Sirisa-ard P, Srisa-nga P, ChansaKaow S, Nathakarnkitkul S,. 2011. Medicinal plants of the Mien (Yao) in Northern Thailand and their potential value in the primary healthcare of postpartum women. J Ethnopharmacol 135: 226-237.
33. Pradhan BK, Badola HK,. 2008. Ethnomedicinal plant use by Lepcha tribe of Dzongu valley, bordering Khangchendzonga Biosphere Reserve, in North Sikkim, India. J Ethnobiol Ethnomed 4: 22.
34. Rasul A, Khan M, Yu B, et al,. 2013. Isoalantolactone, a sesquiterpene lactone, induces apoptosis in SGC-7901 cells via mitochondrial and phosphatidylinositol 3-kinase/Akt signaling pathways. Arch Pharm Res 36: 1262-1269.
35. Sapsrithong T, Kaewprem W, Tongumpai S, Nusuetrong P, Meksuriyen D,. 2012. Cissus quadrangularis ethanol extract upregulates superoxide dismutase, glutathione peroxidase and endothelial nitric oxide synthase expression in hydrogen peroxide-injured human ECV304 cells. J Ethnopharmacol 143: 664-672.
36. Seok Yang W, Lee J, Woong Kim T, et al,. 2012. Src/NF-kappaB-targeted inhibition of LPS-induced macrophage activation and dextran sodium sulphate-induced colitis by Archidendron clypearia methanol extract. J Ethnopharmacol 142: 287-293.
37. Slomiany BL, Slomiany A,. 2008. Src kinase-mediated parallel activation of prostaglandin and constitutive nitric oxide synthase pathways in leptin protection of gastric mucosa against ethanol cytotoxicity. J Physiol Pharmacol 59: 301-314.
38. Smolinska MJ, Horwood NJ, Page TH, Smallie T, Foxwell BM,. 2008. Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Mol Immunol 45: 990-1000.
39. Vogt PK, Hart JR, Gymnopoulos M, et al,. 2010. Phosphatidylinositol 3-kinase: the oncoprotein. Curr Top Microbiol Immunol 347: 79-104.
40. Xu AN, Chen XH, Tan YH, et al,. 2013. Identification of a novel circularized transcript of the AML1 gene. BMB Rep 46: 163-168.
41. Yang WS, Jeong D, Nam G, et al,. 2013a. AP-1 pathway-targeted inhibition of inflammatory responses in LPS-treated macrophages and EtOH/HCl-treated stomach by Archidendron clypearia methanol extract. J Ethnopharmacol 146: 637-644.
42. Yang WS, Lee BH, Kim SH, et al,. 2013b. Dipterocarpus tuberculatus ethanol extract strongly suppresses in vitro macrophage-mediated inflammatory responses and in vivo acute gastritis. J Ethnopharmacol 146: 873-880.
43. Yang Y, Kim SC, Yu T, et al,. 2014. Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses. Mediators Inflamm 2014: 352371.
44. Yang Y, Lee GJ, Yoon DH, et al,. 2013c. ERK1- and TBK1-targeted anti-inflammatory activity of an ethanol extract of Dryopteris crassirhizoma. J Ethnopharmacol 145: 499-508.
45. Youn CK, Park SJ, Lee MY, et al,. 2013. Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells. Biomol Ther (Seoul) 21: 258-263.
46. Yu T, Ahn HM, Shen T, et al,. 2011. Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. J Ethnopharmacol 137: 1197-1206.
47. Yu T, Lee S, Yang WS, et al,. 2012a. The ability of an ethanol extract of Cinnamomum cassia to inhibit Src and spleen tyrosine kinase activity contributes to its anti-inflammatory action. J Ethnopharmacol 139: 566-573.
48. Yu T, Yi YS, Yang Y, Oh J, Jeong D, Cho JY,. 2012b. The pivotal role of TBK1 in inflammatory responses mediated by macrophages. Mediators Inflamm 2012: 979105.