Mycobacterium tuberculosis-induced expression of granulocyte-macrophage colony stimulating factor is mediated by PI3-K/MEK1/p38 MAPK signaling pathway

BMB Reports

Volumn 46, Issue 4, 2013, Pages 213-218

  Cho, Jang Eun ^a   Park, Sangjung ^b   Lee, Hyeyoung ^b   Cho, Sang Nae ^c   Kim, Yoon Suk ^b  

^a Daegu Health College   (South Korea)

^b Yonsei University Wonju   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

GM CSF; MEK1; Mycobacterium tuberculosis; P38 MAPK; PI3 K

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR;

ARTICLE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; SIGNAL TRANSDUCTION; UPREGULATION;

CELL LINE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; MAP KINASE KINASE 1; MYCOBACTERIUM TUBERCULOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84880634088     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2013.46.4.200     Document Type: Article

References (35)

1. World Health Organization. WHO report 2007: Global tuberculosis control; surveillance, planning, financing. Geneva: WHO 2007, pp.1-277.
2. World Health Organization. WHO report 2007: Global MDR-TB and XDR-TB response plan 2007-2008. Geneva: WHO 2007, pp.1-48.
3. Fenton, M. J. (1998) Macrophages and tuberculosis. Curr. Opin. Hematol. 5, 72-78.
4. Cooper, A. M. and Khader, S. A. (2008) The role of cytokines in the initiation, expansion, and control of cellular immuniy to tuberculosis. Immunol. Rev. 226, 191-204.
5. Peters, W. and Ernst, J. D. (2003) Mechanisms of cell recruitment in the immune response to Mycobacterium tuberculosis. Microbes Infect. 5, 151-158.
6. Law, K., Weiden, M., Harkin, T., Tchou-Wong, K., Chi, C. and Rom, W. N. (1996) Increased release of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha by bronchoalveolar cells lavaged from involved sites in pulmonary tuberculosis. Am. J. Respir. Crit. Care. Med. 153, 799-804.
7. Majumder, N., Bhattacharjee, S., Bhattacharyya (Majumdar), S., Dey, R., Guha, P., Pal, N. K. and Majumdar, S. (2008) Restoration of impaired free radical generation and proinflammatory cytokines by MCP-1 in mycobacterial pathogenesis. Scand. J. Immunol. 67, 329-339.
8. Ferrara, G., Bleck, B., Richeldi, L., Reibman, J., Fabbri, L. M., Rom, W. N. and Condos, R. (2008) Mycobacterium tuberculosis induces CCL18 expression in human macrophages. Scand. J. Immunol. 68, 668-674.
9. Jin, H. T., Jeong, Y. H., Park, H. J. and Ha, S. J., (2011) Mechanism of T cell exhaustion in a chronic environment. BMB Rep. 44, 271-233.
10. Burger, J. A., Baird, S. M., Powell, H. C., Sharma, S., Eling, D. J. and Kipps, T. J. (2000) Local and systemic effects after adenoviral transfer of the murine granulocyte-macrophage colony-stimulating factor gene into mice. Br. J. Haematol. 108, 641-652.
11. Feetwood, A. J., Cook, A. D. and Hamilton, J. A. (2005) Functions of granulocyte-macrophage colony-stimulating factor. Crit. Rev. Immunol. 25, 405-428.
12. Daro, E., Butz, E., Smith, J., Teepe, M., Maliszewski, C. R. and McKenna, H. J. (2002) Comparison of the functional properties of murine dendritc cells generated in vivo with Flt3 ligand, GM-CSF and Flt3 ligand plus GM-CSF. Cytokine 17, 119-130.
13. Yuan, S., Shi, C., Han, W., Ling, R., Li, N. and Wang, T. (2009) Effective anti-tumor responses induced by recombinant bacillus Calmette-Guerin vaccines based on different tandem repeats of MUC1 and GM-CSF. Eur. J. Cancer. Prev. 18, 416-423.
14. Miller, G., Pillarisetty, V. G., Shah, A. B., Lahrs, S., Xing, Z. and Dematteo, R. P. (2002) Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function. J. Immunol. 169, 2875-2885.
15. Shibata, Y., Berclaz, P. Y., Chroneos, Z. C., Yoshida, M., Whitsett, J. A. and Trapnell, B. C. (2001) GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity 15, 557-567.
16. Shi, Y., Liu, C. H., Roberts, A. I., Das, J., Xu, G., Ren, G., Zhang, Y., Zhang, L., Yuan, Z. R., Tan, H. S., Das, G. and Devadas, S. (2006) Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res. 16, 126-133.
17. Lin, H. S., Lokeshwar, B. L. and Hsu, S. (1989) Both granulocyte-macrophage CSF and macrophage CSF control the proliferation and survival of the same subset of alveolar macrophage. J. Immunol. 142, 515-519.
18. Gonzalez-Juarrero, M., Hattle, J. M., Izzo, A., Junqueira-Kipnis, A. P., Shim, T. S., Trapnell, B. C. and Copper A. M. (2005) Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection. J. Leukoc. Biol. 77, 914-922.
19. Ordway, D., Henao-Tamayo, M., Orme, I. M. and Gonzalez-Juarrero, M. (2005) Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapototic markers of the TNF receptor-associated factor family. J. Immunol. 175, 3873-3881.
20. Shibata, Y., Berclaz, P. Y., Chroneos, Z. C., Yoshida, M., Whitsett, J. A. and Trapnell, B. C. (2001) GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity 15, 557-567.
21. Yoshie, O., Imai, T. and Nomiyama, H. (2001). Chemokines in immunity. Adv. Immunol. 78, 57-110.
22. Saukkonen, J. J., Bazydlo, B., Thomas, M., Strieter, R. M., Keane, J. and Kornfeld, H., (2002). Beta-chemokines are induced by Mycobacterium tuberculosis and inhibit its growth. Infect. Immun. 70, 1684-1693.
23. Cho, J. E., Kim, Y. S., Park, S., Cho, S. N. and Lee, H. (2010) Mycobacterium tuberculosis-induced expression of Leukotactin-1 is mediated by the PI3-K/PDK1/Akt signaling pathway. Mol. Cells 29, 35-39.
24. Cho, J. E., Park, S., Cho, S. N., Lee, H. and Kim, Y. S. (2012) c-Jun N-terminal (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) are involved in Mycobacterium tuberculosis-induced expression of Leukotactin-1. BMB Rep. 45, 583-588.
25. Elagoz, A., Henderson, D., Babu, P. S., Salter, S., Grahames, C., Bowers, L., Roy, M. O., Laplante, P., Grazzini, E., Ahmad, S. and Lembo, P. M. (2004) A truncated form of CKbeta8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor. Br. J. Pharmacol. 141, 37-46.
26. Youn, B. S., Zhang, S. M., Broxmeyer, H. E., Cooper, S., Antol, K., Fraser, M. Jr. and Kwon, B. S. (1998) Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1. Blood 91, 3118-3126.
27. Lim, Y., Gong, J., Zhang, M., Xue, W. and Barnes, P. F. (1998) Production on monocyte chemoattractant Protein 1 in Tuberculosis Patients. Infect. Immun. 66, 2319-2322.
28. Ordway, D., Harton, M., Henao-Tamayo, M., Montoya, R., Orme, I. M. and Gonzalez-Juarrero, M. (2006) Enhanced macrophage activity in granulomatous lesions of immune mice challenged with Mycobacterium tuberculosis. J. Immunol. 176, 4931-4939.
29. Soilleux, E. J., Morris, L. S., Leslie, G., Chehimi, J., Luo, Q., Levroney, E., Trowsdale, J., Montaner, L. J., Doms, R. W., Weissman, D., Coleman, N. and Lee, B. (2002) Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulation in situ and in vitro. J. Leukoc. Biol. 71, 445-457.
30. Wolf, A. J., Linas, B., Trevejo-Nunez, G. J., Kincaid, E., Tamura, T., Takatsu, K. and Ernst, J. D. (2007) Mycobacterim tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J. Immunol. 179, 2509-2519.
31. North, R. J. and Jung, Y. J. (2004) Immunity to tuberculosis. Annu. Rev. Immunol. 22, 599-623.
32. Roilides, E., Walsh, T. J., Pizzo, P. A. and Rubin, M. (1991) Granulocyte-stimulating factor enhances the phagocytic and bactericidal activity of normal and defective human neutrophil. J. Infect. Dis. 163, 579-583.
33. Chung, H. K., Kim, S. W., Byun, S. J., Ko, E. M., Chung, H. J., Woo, J. S., Yoo, J. G., Lee, H. C., Yang, B. C., Kwon, M., Park, S. B., Park, J. K. and Kim, K. W. (2011) Enhanced biological effects of Phe140Asn, a novel human granulocyte colony-stimulating factor mutant, on HL60 cells. BMB Rep. 44, 686-691.
34. Lin, H. S., Lokeshwar, B. L. and Hsu, S. (1989) Both granulocyte-macrophage CSF and macrophage CSF control the proliferation and survival of the same subset of alveolar macrophages. J. Immunol. 142, 515-519.
35. Higgins, D. M., Sanchez-Campillo, J., Rosas-Taraco, A. G., Higgins, J. R., Lee, E. J., Orme, I. M. and Gonzalez-Juarrero, M. (2008) Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis. J. Immunol. 180, 4892-4900.