메뉴 건너뛰기




Volumn 34, Issue 5, 2015, Pages 653-668

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

Author keywords

alternative splicing; Matrin3; PTB

Indexed keywords

MATRILYSIN; MATRILYSIN 3; NUCLEAR MATRIX PROTEIN; UNCLASSIFIED DRUG; MATR3 PROTEIN, HUMAN; POLYPYRIMIDINE TRACT BINDING PROTEIN; PRIMER DNA; RNA BINDING PROTEIN; SMALL INTERFERING RNA;

EID: 84924036454     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201489852     Document Type: Article
Times cited : (113)

References (84)
  • 3
    • 0036918231 scopus 로고    scopus 로고
    • Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain
    • Bernert G, Fountoulakis M, Lubec G, (2002) Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain. Proteomics 2: 1752-1757
    • (2002) Proteomics , vol.2 , pp. 1752-1757
    • Bernert, G.1    Fountoulakis, M.2    Lubec, G.3
  • 4
    • 77952627699 scopus 로고    scopus 로고
    • MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis
    • Bimpaki EI, Iliopoulos D, Moraitis A, Stratakis CA, (2009) MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis. Clin Endocrinol (Oxf) 72: 744-751
    • (2009) Clin Endocrinol (Oxf) , vol.72 , pp. 744-751
    • Bimpaki, E.I.1    Iliopoulos, D.2    Moraitis, A.3    Stratakis, C.A.4
  • 6
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe BJ, (2006) Alternative splicing: new insights from global analyses. Cell 126: 37-47
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 7
    • 34347384211 scopus 로고    scopus 로고
    • A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
    • Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M Jr, Black DL, (2007) A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev 21: 1636-1652
    • (2007) Genes Dev , vol.21 , pp. 1636-1652
    • Boutz, P.L.1    Stoilov, P.2    Li, Q.3    Lin, C.H.4    Chawla, G.5    Ostrow, K.6    Shiue, L.7    Ares, Jr.M.8    Black, D.L.9
  • 9
    • 84861929838 scopus 로고    scopus 로고
    • TDP-43: Gumming up neurons through protein-protein and protein-RNA interactions
    • Buratti E, Baralle FE, (2012) TDP-43: gumming up neurons through protein-protein and protein-RNA interactions. Trends Biochem Sci 37: 237-247
    • (2012) Trends Biochem Sci , vol.37 , pp. 237-247
    • Buratti, E.1    Baralle, F.E.2
  • 13
    • 56749164864 scopus 로고    scopus 로고
    • Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
    • Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM, (2008) Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines. Nat Genet 40: 1416-1425
    • (2008) Nat Genet , vol.40 , pp. 1416-1425
    • Castle, J.C.1    Zhang, C.2    Shah, J.K.3    Kulkarni, A.V.4    Kalsotra, A.5    Cooper, T.A.6    Johnson, J.M.7
  • 17
    • 84934435678 scopus 로고    scopus 로고
    • Regulation of alternative pre-mRNA splicing
    • Coelho MB, Smith CW, (2014) Regulation of alternative pre-mRNA splicing. Methods Mol Biol 1126: 55-82
    • (2014) Methods Mol Biol , vol.1126 , pp. 55-82
    • Coelho, M.B.1    Smith, C.W.2
  • 19
    • 34250363024 scopus 로고    scopus 로고
    • SR proteins function in coupling RNAP II transcription to pre-mRNA splicing
    • Das R, Yu J, Zhang Z, Gygi MP, Krainer AR, Gygi SP, Reed R, (2007) SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol Cell 26: 867-881
    • (2007) Mol Cell , vol.26 , pp. 867-881
    • Das, R.1    Yu, J.2    Zhang, Z.3    Gygi, M.P.4    Krainer, A.R.5    Gygi, S.P.6    Reed, R.7
  • 21
    • 80054757242 scopus 로고    scopus 로고
    • Direct identification of insulator components by insertional chromatin immunoprecipitation
    • Fujita T, Fujii H, (2011) Direct identification of insulator components by insertional chromatin immunoprecipitation. PLoS One 6: e26109
    • (2011) PLoS One , vol.6 , pp. e26109
    • Fujita, T.1    Fujii, H.2
  • 26
    • 0026683289 scopus 로고
    • Affinity of a highly repetitive bent DNA for nuclear scaffold proteins from rat liver
    • Hibino Y, Nakamura K, Asano S, Sugano N, (1992) Affinity of a highly repetitive bent DNA for nuclear scaffold proteins from rat liver. Biochem Biophys Res Commun 184: 853-858
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 853-858
    • Hibino, Y.1    Nakamura, K.2    Asano, S.3    Sugano, N.4
  • 27
    • 0034627115 scopus 로고    scopus 로고
    • Transcription modulation by a rat nuclear scaffold protein, P130, and a rat highly repetitive DNA component or various types of animal and plant matrix or scaffold attachment regions
    • Hibino Y, Ohzeki H, Sugano N, Hiraga K, (2000) Transcription modulation by a rat nuclear scaffold protein, P130, and a rat highly repetitive DNA component or various types of animal and plant matrix or scaffold attachment regions. Biochem Biophys Res Commun 279: 282-287
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 282-287
    • Hibino, Y.1    Ohzeki, H.2    Sugano, N.3    Hiraga, K.4
  • 28
  • 32
  • 34
    • 82955205878 scopus 로고    scopus 로고
    • Crystallographic analysis of polypyrimidine tract-binding protein-Raver1 interactions involved in regulation of alternative splicing
    • Joshi A, Coelho MB, Kotik-Kogan O, Simpson PJ, Matthews SJ, Smith CW, Curry S, (2011) Crystallographic analysis of polypyrimidine tract-binding protein-Raver1 interactions involved in regulation of alternative splicing. Structure 19: 1816-1825
    • (2011) Structure , vol.19 , pp. 1816-1825
    • Joshi, A.1    Coelho, M.B.2    Kotik-Kogan, O.3    Simpson, P.J.4    Matthews, S.J.5    Smith, C.W.6    Curry, S.7
  • 36
    • 84862679962 scopus 로고    scopus 로고
    • Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2
    • Keppetipola N, Sharma S, Li Q, Black DL, (2012) Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2. Crit Rev Biochem Mol Biol 47: 360-378
    • (2012) Crit Rev Biochem Mol Biol , vol.47 , pp. 360-378
    • Keppetipola, N.1    Sharma, S.2    Li, Q.3    Black, D.L.4
  • 39
    • 79960558747 scopus 로고    scopus 로고
    • Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function
    • Kula A, Guerra J, Knezevich A, Kleva D, Myers MP, Marcello A, (2011) Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology 8: 60
    • (2011) Retrovirology , vol.8 , pp. 60
    • Kula, A.1    Guerra, J.2    Knezevich, A.3    Kleva, D.4    Myers, M.P.5    Marcello, A.6
  • 40
    • 84871676628 scopus 로고    scopus 로고
    • HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3
    • Kula A, Gharu L, Marcello A, (2012) HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3. Virology 435: 329-340
    • (2012) Virology , vol.435 , pp. 329-340
    • Kula, A.1    Gharu, L.2    Marcello, A.3
  • 42
    • 72849106592 scopus 로고    scopus 로고
    • RNA processing and its regulation: Global insights into biological networks
    • Licatalosi DD, Darnell RB, (2010) RNA processing and its regulation: global insights into biological networks. Nat Rev Genet 11: 75-87
    • (2010) Nat Rev Genet , vol.11 , pp. 75-87
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 43
    • 0036214013 scopus 로고    scopus 로고
    • Mutations in RRM4 uncouple the splicing repression and RNA-binding activities of polypyrimidine tract binding protein
    • Liu H, Zhang W, Reed RB, Liu W, Grabowski PJ, (2002) Mutations in RRM4 uncouple the splicing repression and RNA-binding activities of polypyrimidine tract binding protein. RNA 8: 137-149
    • (2002) RNA , vol.8 , pp. 137-149
    • Liu, H.1    Zhang, W.2    Reed, R.B.3    Liu, W.4    Grabowski, P.J.5
  • 46
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev EV, Zhang J, Carrasco MA, Maniatis T, (2007) The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27: 435-448
    • (2007) Mol Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 47
    • 54849442463 scopus 로고    scopus 로고
    • Identifying functional neighborhoods within the cell nucleus: Proximity analysis of early S-phase replicating chromatin domains to sites of transcription, RNA polymerase II, HP1gamma, matrin 3 and SAF-A
    • Malyavantham KS, Bhattacharya S, Barbeitos M, Mukherjee L, Xu J, Fackelmayer FO, Berezney R, (2008) Identifying functional neighborhoods within the cell nucleus: proximity analysis of early S-phase replicating chromatin domains to sites of transcription, RNA polymerase II, HP1gamma, matrin 3 and SAF-A. J Cell Biochem 105: 391-403
    • (2008) J Cell Biochem , vol.105 , pp. 391-403
    • Malyavantham, K.S.1    Bhattacharya, S.2    Barbeitos, M.3    Mukherjee, L.4    Xu, J.5    Fackelmayer, F.O.6    Berezney, R.7
  • 48
    • 84892511644 scopus 로고    scopus 로고
    • Large-scale gene function analysis with the PANTHER classification system
    • Mi H, Muruganujan A, Casagrande JT, Thomas PD, (2013) Large-scale gene function analysis with the PANTHER classification system. Nat Protoc 8: 1551-1566
    • (2013) Nat Protoc , vol.8 , pp. 1551-1566
    • Mi, H.1    Muruganujan, A.2    Casagrande, J.T.3    Thomas, P.D.4
  • 50
    • 0032529163 scopus 로고    scopus 로고
    • The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3? End formation by two distinct mechanisms
    • Moreira A, Takagaki Y, Brackenridge S, Wollerton M, Manley JL, Proudfoot NJ, (1998) The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3? end formation by two distinct mechanisms. Genes Dev 12: 2522-2534
    • (1998) Genes Dev , vol.12 , pp. 2522-2534
    • Moreira, A.1    Takagaki, Y.2    Brackenridge, S.3    Wollerton, M.4    Manley, J.L.5    Proudfoot, N.J.6
  • 51
    • 0025790440 scopus 로고
    • Nuclear matrins: Identification of the major nuclear matrix proteins
    • Nakayasu H, Berezney R, (1991) Nuclear matrins: identification of the major nuclear matrix proteins. Proc Natl Acad Sci USA 88: 10312-10316
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10312-10316
    • Nakayasu, H.1    Berezney, R.2
  • 52
    • 75849145292 scopus 로고    scopus 로고
    • Expansion of the eukaryotic proteome by alternative splicing
    • Nilsen TW, Graveley BR, (2010) Expansion of the eukaryotic proteome by alternative splicing. Nature 463: 457-463
    • (2010) Nature , vol.463 , pp. 457-463
    • Nilsen, T.W.1    Graveley, B.R.2
  • 55
    • 0041372953 scopus 로고    scopus 로고
    • Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein
    • Perez I, McAfee JG, Patton JG, (1997) Multiple RRMs contribute to RNA binding specificity and affinity for polypyrimidine tract binding protein. Biochemistry 36: 11881-11890
    • (1997) Biochemistry , vol.36 , pp. 11881-11890
    • Perez, I.1    McAfee, J.G.2    Patton, J.G.3
  • 56
    • 0034612372 scopus 로고    scopus 로고
    • A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing
    • Polydorides AD, Okano HJ, Yang YY, Stefani G, Darnell RB, (2000) A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proc Natl Acad Sci USA 97: 6350-6355
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6350-6355
    • Polydorides, A.D.1    Okano, H.J.2    Yang, Y.Y.3    Stefani, G.4    Darnell, R.B.5
  • 57
    • 79952185328 scopus 로고    scopus 로고
    • Matrin 3 as a key regulator of endothelial cell survival
    • Przygodzka P, Boncela J, Cierniewski CS, (2010) Matrin 3 as a key regulator of endothelial cell survival. Exp Cell Res 317: 802-811
    • (2010) Exp Cell Res , vol.317 , pp. 802-811
    • Przygodzka, P.1    Boncela, J.2    Cierniewski, C.S.3
  • 58
    • 84863304598 scopus 로고    scopus 로고
    • R Development Core Team. R Foundation for Statistical Computing Vienna, Austria: ISBN 3-900051-07-0, URL.
    • R Development Core Team (2011) R: A language and Environment for Statistical Computing. R Foundation for Statistical Computing Vienna, Austria: ISBN 3-900051-07-0, URL http://www.R-project.org/.
    • (2011) R: A Language and Environment for Statistical Computing
  • 61
    • 33644861782 scopus 로고    scopus 로고
    • A splicing repressor domain in polypyrimidine tract-binding protein
    • Robinson F, Smith CW, (2006) A splicing repressor domain in polypyrimidine tract-binding protein. J Biol Chem 281: 800-806
    • (2006) J Biol Chem , vol.281 , pp. 800-806
    • Robinson, F.1    Smith, C.W.2
  • 62
    • 77953564663 scopus 로고    scopus 로고
    • Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response
    • Salton M, Lerenthal Y, Wang SY, Chen DJ, Shiloh Y, (2010) Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response. Cell Cycle 9: 1568-1576
    • (2010) Cell Cycle , vol.9 , pp. 1568-1576
    • Salton, M.1    Lerenthal, Y.2    Wang, S.Y.3    Chen, D.J.4    Shiloh, Y.5
  • 64
    • 49349112872 scopus 로고    scopus 로고
    • Polypyrimidine-tract-binding protein: A multifunctional RNA-binding protein
    • Sawicka K, Bushell M, Spriggs KA, Willis AE, (2008) Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein. Biochem Soc Trans 36: 641-647
    • (2008) Biochem Soc Trans , vol.36 , pp. 641-647
    • Sawicka, K.1    Bushell, M.2    Spriggs, K.A.3    Willis, A.E.4
  • 68
    • 0029055472 scopus 로고
    • Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
    • Singh R, Valcarcel J, Green MR, (1995) Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science 268: 1173-1176
    • (1995) Science , vol.268 , pp. 1173-1176
    • Singh, R.1    Valcarcel, J.2    Green, M.R.3
  • 70
    • 34547205013 scopus 로고    scopus 로고
    • Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1
    • Spellman R, Llorian M, Smith CW, (2007) Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1. Mol Cell 27: 420-434
    • (2007) Mol Cell , vol.27 , pp. 420-434
    • Spellman, R.1    Llorian, M.2    Smith, C.W.3
  • 71
    • 0035038207 scopus 로고    scopus 로고
    • Polypyrimidine tract binding protein antagonizes exon definition
    • Wagner EJ, Garcia-Blanco MA, (2001) Polypyrimidine tract binding protein antagonizes exon definition. Mol Cell Biol 21: 3281-3288
    • (2001) Mol Cell Biol , vol.21 , pp. 3281-3288
    • Wagner, E.J.1    Garcia-Blanco, M.A.2
  • 74
    • 79952105381 scopus 로고    scopus 로고
    • Understanding splicing regulation through RNA splicing maps
    • Witten JT, Ule J, (2011) Understanding splicing regulation through RNA splicing maps. Trends Genet 27: 89-97
    • (2011) Trends Genet , vol.27 , pp. 89-97
    • Witten, J.T.1    Ule, J.2
  • 75
    • 0034977633 scopus 로고    scopus 로고
    • Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB)
    • Wollerton MC, Gooding C, Robinson F, Brown EC, Jackson RJ, Smith CW, (2001) Differential alternative splicing activity of isoforms of polypyrimidine tract binding protein (PTB). RNA 7: 819-832
    • (2001) RNA , vol.7 , pp. 819-832
    • Wollerton, M.C.1    Gooding, C.2    Robinson, F.3    Brown, E.C.4    Jackson, R.J.5    Smith, C.W.6
  • 76
    • 0346124413 scopus 로고    scopus 로고
    • Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay
    • Wollerton MC, Gooding C, Wagner EJ, Garcia-Blanco MA, Smith CW, (2004) Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol Cell 13: 91-100
    • (2004) Mol Cell , vol.13 , pp. 91-100
    • Wollerton, M.C.1    Gooding, C.2    Wagner, E.J.3    Garcia-Blanco, M.A.4    Smith, C.W.5
  • 77
    • 72149117411 scopus 로고    scopus 로고
    • Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping
    • Xue Y, Zhou Y, Wu T, Zhu T, Ji X, Kwon YS, Zhang C, Yeo G, Black DL, Sun H, Fu XD, Zhang Y, (2009) Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell 36: 996-1006
    • (2009) Mol Cell , vol.36 , pp. 996-1006
    • Xue, Y.1    Zhou, Y.2    Wu, T.3    Zhu, T.4    Ji, X.5    Kwon, Y.S.6    Zhang, C.7    Yeo, G.8    Black, D.L.9    Sun, H.10    Fu, X.D.11    Zhang, Y.12
  • 79
    • 79960558040 scopus 로고    scopus 로고
    • Matrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expression
    • Yedavalli VS, Jeang KT, (2011) Matrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expression. Retrovirology 8: 61
    • (2011) Retrovirology , vol.8 , pp. 61
    • Yedavalli, V.S.1    Jeang, K.T.2
  • 82
    • 84881493949 scopus 로고    scopus 로고
    • Prediction of clustered RNA-binding protein motif sites in the mammalian genome
    • Zhang C, Lee KY, Swanson MS, Darnell RB, (2013) Prediction of clustered RNA-binding protein motif sites in the mammalian genome. Nucleic Acids Res 41: 6793-6807
    • (2013) Nucleic Acids Res , vol.41 , pp. 6793-6807
    • Zhang, C.1    Lee, K.Y.2    Swanson, M.S.3    Darnell, R.B.4
  • 83
    • 0035943347 scopus 로고    scopus 로고
    • The fate of dsRNA in the nucleus: A p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs
    • Zhang Z, Carmichael GG, (2001) The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs. Cell 106: 465-475
    • (2001) Cell , vol.106 , pp. 465-475
    • Zhang, Z.1    Carmichael, G.G.2
  • 84
    • 0035691667 scopus 로고    scopus 로고
    • Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins
    • Zhu J, Mayeda A, Krainer AR, (2001) Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins. Mol Cell 8: 1351-1361
    • (2001) Mol Cell , vol.8 , pp. 1351-1361
    • Zhu, J.1    Mayeda, A.2    Krainer, A.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.